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picu acute severe asthma children mechanical ventilation sepsis aiims patna functional abdominal pain functional constipation lokesh tiwari status asthmaticus bronchial asthma functional nausea pediatrics holliday segar formula hyponatremia in hospitalized children fluid therapy in children basic modes pediatric ventilation respiratory failure functional gastrointestinal disorders simd snakebite envenomation septic shock inotrop fgid