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biomechanics femur huiskes model gamma nail bone adaptation finite elements deep vein thrombosis superficial thrombophlebitis blood vessel disorders hematoglutinine influenza virus ehhs cell culture multiple bodies model human gait matlab baumgarte stabilization dynamic elasticity theory finite element method biomechanical modeling ansys deformed structure stem cell therapy movement disorders parkinsons disease deep brain stimulation ablation bioimpedance kubicek model icg