This document provides an overview of logic and legal reasoning, specifically focusing on the proper use of syllogisms in legal arguments. It explains that a valid legal argument must follow the form of a logic syllogism, consisting of a major premise stating a legal rule, a minor premise making a factual statement, and a conclusion connecting the law to the facts. The document also discusses logical fallacies that weaken arguments, specifically "fallacies of relevance" where premises fail to support the conclusion and "fallacies of ambiguity" where terms shift meaning. It provides examples of common fallacies like appealing to inappropriate authority and having disconnected premises to avoid in legal writing.
The document discusses legal reasoning and problem solving techniques for writing effective legal essays. It presents a 4-step method (CLEO) for legal analysis and writing: 1) Identify the claim, 2) Present the applicable law, 3) Evaluate the facts of the problem, and 4) Identify the outcome of the argument. Within each step, it provides guidance on how to structure arguments and effectively analyze problems using techniques like deductive, inductive, and analogical reasoning.
Various Constituents of Legal Literature
Understanding the various parts of the statutes
Relevance of General Clauses Act, 1897 in the Interpretation of statutes
Various Parts & Sections of Gazette of India
Distinctiveness of ratio decidendi & obiter dicta
Relation of Logic to Laws
Concept of Deductive and Inductive Reasoning as Tools of Legal Reasoning
The document discusses the importance of logical reasoning skills for legal studies and practice. It outlines three main forms of logical reasoning used in law: deductive reasoning, inductive generalization, and analogy. Deductive reasoning involves proving a conclusion through major and minor premises. Inductive generalization arrives at broad conclusions based on specific examples. Analogy compares two things to draw conclusions about both. Understanding these logical reasoning structures is critical for legal writing, arguments, and success in law school.
Introduction to inductive and deductive reasoningrbangerter
油
The document provides an introduction to inductive and deductive reasoning. It explains that inductive reasoning uses specific examples to derive a probable conclusion about all cases, while deductive reasoning applies a general principle to a specific instance to logically conclude. Several examples of inductive and deductive arguments are given to illustrate the concepts.
The document discusses various methods for resolving disputes, including litigation and alternative dispute resolution. It provides details on civil and criminal court processes, as well as hierarchical court structures. It also outlines pre-trial procedures, trials, judgments, and methods of enforcing judgments. Additionally, it discusses administrative law and tribunals, judicial review, and alternative dispute resolution methods like negotiation, mediation, and arbitration.
The document provides an overview of key concepts in Canadian law, including:
1) It defines law and discusses philosophical bases like natural law theory and legal positivism.
2) It outlines categories of laws like substantive and procedural law, and legal systems like civil law and common law.
3) It discusses important sources of Canadian law like the constitution, statutes, and common law, as well as the division of powers between federal and provincial governments.
4) It describes the Canadian Charter of Rights and Freedoms and how it protects individual rights and freedoms.
Drugs acting on Respiratory System: Anti-Athmatic Drugs.pptxSivaGanesh552177
油
The topic " Anti-Asthmatic Drugs" is covered under Unit I of the Pharmacology of Drugs Acting on the Respiratory System, which is included in the course of Pharmacology III with course code BP602.
Learning Objectives:
1. Explain the basis of Nernst potential and its importance in generation of resting membrane potential
2. Comprehend different mechanisms responsible for the genesis of membrane potential
3. Use the Goldman equation to explain how the relative permeability of the ions create a resting membrane potential
Understanding the Impact of Revalidation on UK Healthcare Professionals.pdfMedical Apprisal
油
Revalidation UK is a vital process ensuring healthcare professionals maintain high standards, enhancing patient safety and public trust. This mandatory assessment promotes continuous professional development, requiring practitioners to demonstrate competence, adhere to ethical guidelines, and engage in reflective practice. Despite challenges like administrative burdens and balancing clinical duties, revalidation fosters lifelong learning and accountability. Employers and regulatory bodies play a key role in supporting professionals through training, mentorship, and streamlined appraisal processes. As technology advances, revalidation UK will evolve to simplify compliance and enhance accessibility. By embracing revalidation, healthcare professionals contribute to a safer, more effective healthcare system, reinforcing trust and excellence in patient care across the UK.
Classification of Selective Alpha Agonists Based on Generation
Selective alpha agonists can be classified into first-generation, second-generation, and third-generation based on their pharmacological properties, receptor specificity, and clinical applications.
1. First-Generation Selective Alpha Agonists
(Non-subtype selective, older agents, higher side effects)
These drugs act on 留1 or 留2 receptors but with lower specificity and more systemic side effects.
Selective 留1 Agonists (Vasoconstrictors, Hypotension Treatment)
Methoxamine Used to treat hypotension.
Phenylephrine Used as a nasal decongestant and to increase blood pressure.
Midodrine Used for orthostatic hypotension.
Metaraminol Used in hypotensive states and shock.
Selective 留2 Agonists (Centrally Acting, Anti-Hypertensive Drugs)
Clonidine Used for hypertension, ADHD, and withdrawal syndromes.
Methyldopa Used for hypertension, especially in pregnancy.
Guanfacine Used in hypertension and ADHD.
2. Second-Generation Selective Alpha Agonists
(More receptor selectivity, improved safety profile, fewer side effects)
Selective 留1 Agonists (Longer Duration, Specific Targeting)
Amidephrine Used in hypotension.
Selective 留2 Agonists (Better CNS Penetration, Neurological Uses)
Brimonidine Used in glaucoma (reduces intraocular pressure).
Apraclonidine Used in short-term treatment of glaucoma.
Tizanidine Used as a muscle relaxant in spasticity.
Lofexidine Used in opioid withdrawal treatment.
3. Third-Generation Selective Alpha Agonists
(Highly selective, fewer side effects, newer therapeutic applications)
Selective 留2 Agonists (High Selectivity, Novel Applications)
Dexmedetomidine Used as a sedative in ICU and anesthesia.
Medetomidine Used in veterinary anesthesia.
Fadolmidine Investigated for pain relief with fewer cardiovascular effects.
Detomidine Used in veterinary medicine for sedation
Classification of Selective Beta Agonists Based on Generation
Selective 硫-adrenergic agonists can be classified into three generations based on their receptor selectivity, duration of action, and therapeutic advancements.
1. First-Generation Selective Beta Agonists
(Non-specific, Short-acting, Higher Side Effects)
Early 硫-agonists with partial selectivity, often affecting both 硫1 and 硫2 receptors.
Shorter duration of action, leading to frequent dosing requirements.
Key Drugs:
Isoproterenol A non-selective 硫1 and 硫2 agonist, used for bradycardia and heart block.
Dobutamine A selective 硫1 agonist, used in acute heart failure and cardiogenic shock.
Ritodrine A selective 硫2 agonist, previously used for delaying preterm labor.
2. Second-Generation Selective Beta Agonists
(More Selective, Longer Duration, Improved Safety)
These drugs show improved selectivity for either 硫1 or 硫2 receptors, reducing unwanted cardiac effects.
Longer-acting compared to first-generation.
Selective 硫1 Agonists (Primarily Cardiac Stimulants)
Denopamine Used in heart failure treatment.
Prenalte
The title "Nasal Decongestants and Respiratory Stimulants" is covered under Unit I of the Pharmacology of drugs acting on the Respiratory System, which is included in the course of Pharmacology III with course code BP602.
Drugs acting on Respiratory System: Expectorants and Antitussives.pptxSivaGanesh552177
油
The topic "Expectorants and Antitussives" is covered under Unit I of the Pharmacology of drugs acting on the Respiratory System, which is included in the course of Pharmacology III with course code BP602
PARKINSONS USMLE style question by dr ankush goyalDr Ankush goyal
油
Parkinsonism refers to a clinical syndrome characterized by a combination of motor and non-motor symptoms that resemble Parkinsons disease (PD). It results from dysfunction in the basal ganglia, particularly due to dopamine deficiency in the substantia nigra.
Key Features of Parkinsonism:
1. Bradykinesia Slowness of movement with difficulty in initiating and executing voluntary movements.
2. Rigidity Increased muscle tone, presenting as either:
Lead-pipe rigidity (uniform resistance)
Cogwheel rigidity (intermittent resistance with a ratchet-like quality)
3. Tremor Resting tremor, typically "pill-rolling" (4-6 Hz), that improves with movement.
4. Postural Instability Impaired balance leading to a higher risk of falls.
Causes of Parkinsonism:
1. Idiopathic Parkinsons Disease (PD) The most common cause, due to progressive degeneration of dopaminergic neurons in the substantia nigra.
2. Drug-Induced Parkinsonism Caused by dopamine-blocking agents (e.g., antipsychotics, metoclopramide, reserpine).
3. Atypical Parkinsonian Syndromes (Parkinson-plus syndromes) Progressive conditions with additional features beyond classic Parkinsonism, such as:
Multiple System Atrophy (MSA)
Progressive Supranuclear Palsy (PSP)
Corticobasal Degeneration (CBD)
Dementia with Lewy Bodies (DLB)
4. Vascular Parkinsonism Due to multiple small strokes affecting the basal ganglia.
5. Toxic or Metabolic Causes Includes manganese poisoning, carbon monoxide exposure, Wilsons disease.
6. Post-Encephalitic Parkinsonism Rare, seen in survivors of encephalitis lethargica.
Diagnosis:
Clinical Evaluation Based on cardinal motor symptoms.
Response to Levodopa Helps differentiate PD from other causes.
Neuroimaging (MRI, DaTscan) Useful in atypical cases.
Management:
Pharmacological Treatment:
Levodopa (with carbidopa)
Dopamine agonists (pramipexole, ropinirole)
MAO-B inhibitors (selegiline, rasagiline)
COMT inhibitors (entacapone)
Anticholinergics (for tremors)
Non-Pharmacological Treatment:
Physiotherapy, speech therapy
Deep Brain Stimulation (DBS) in selected cases
### **Acyclovir and Anti-Herpes Medications**
**Acyclovir** is an antiviral medication used to treat infections caused by herpes viruses, including:
- **Herpes simplex virus (HSV-1 & HSV-2)** Causes cold sores and genital herpes.
- **Varicella-zoster virus (VZV)** Causes chickenpox and shingles.
### **Mechanism of Action:**
Acyclovir works by inhibiting viral DNA replication. It is activated inside virus-infected cells, where it blocks viral enzymes, preventing the virus from multiplying.
### **Forms & Dosage:**
- **Oral (Tablets/Capsules/Liquid)** Used for mild to moderate infections.
- **Topical (Cream/Ointment)** For cold sores and mild skin infections.
- **Intravenous (IV)** For severe infections like herpes encephalitis.
### **Other Anti-Herpes Medications:**
- **Valacyclovir (Valtrex)** A prodrug of acyclovir with better absorption.
- **Famciclovir (Famvir)** Another antiviral with a longer duration of action.
- **Penciclovir (Denavir)** Used topically for herpes labialis (cold sores).
### **Uses:**
- Treats and manages outbreaks of herpes simplex.
- Reduces the severity and duration of symptoms.
- Used for long-term suppression to prevent recurrent infections.
- Helps in managing shingles and chickenpox.
### **Side Effects:**
- Nausea, vomiting, diarrhea.
- Headache, dizziness, fatigue.
- Rare: Kidney issues, allergic reactions.
### **Precautions:**
- Drink plenty of fluids to prevent kidney issues.
- Not a cure, but helps manage symptoms.
- Safe for most patients but should be used cautiously in people with kidney disease or weakened immune systems.
We all know that malaria is an infectious disease spread by mosquitos. Female Anopheles mosquitos spread the infection, a microorganism called a plasmodium, when taking a blood meal. But as the quotation often attributed to Mark Twain says What gets us into trouble is not what we dont know. Its what we know for sure that just aint so.
Like most residents of western Europe I thought little about Malaria until I had opportunity to travel to Africa. My destination in Southern Botswana was not on the malaria map. However, parts of the North of the country to which I intended to travel were. People told me I needed to get malaria tablets that had to be taken for a week or two in advance, then daily or weekly and for some time after leaving malaria areas. There were a few different medications and combination tablets available and I investigated which would be the lesser evil. None seemed particularly effective so I decided to check the evidence of the mosquito cause of malaria and how these tablets were supposed to act. I soon became suspicious of the complicated malaria transmission story.
I have written a book 'Malaria is Spread by Mosquitos?'.
This presentation is a short introduction to the topic. see https://usmalaria.com/
Chair, Eleonora Lad, MD, PhD, discusses geographic atrophy in this CME/COPE/IPCE activity titled Improving the Patient Experience in Geographic Atrophy: Are You Putting the Latest Advances Into Practice?. For the full presentation, downloadable Practice Aids, and complete CME/COPE/IPCE information, and to apply for credit, please visit us at https://bit.ly/49lZvbL. CME/COPE/IPCE credit will be available until March 20, 2026.
Let's Talk About It: Gynecologic Cancer (Calm Body, Calm Mind - Using Your Bo...RheannaRandazzo
油
Stress manifests in our thinking, emotions, and bodies. Recognizing those signs and building skills to address stress takes attention and effort. Cultivating skills to use your body as a tool to help you find calm and regain a sense of control can help you navigate moments of heightened anxiety. Join us on Wednesday, March 12th, to learn strategies for quieting your body and, thereby, calming your mind. Lets Talk About It.
TRAGEDIES IN PHASE 1 CLINICAL TRIAL Dr ankush goyalDr Ankush goyal
油
Phase 1 Clinical Trials: An Overview
Phase 1 clinical trials are the first stage of testing a new drug or treatment in humans. These trials primarily assess the safety, tolerability, pharmacokinetics, and pharmacodynamics of the investigational drug. Conducted on a small group of healthy volunteers (typically 20100) or, in certain cases, patients with the target disease, Phase 1 trials aim to determine:
1. Safety and Tolerability Identifying potential side effects and the maximum tolerated dose.
2. Pharmacokinetics (PK) Studying drug absorption, distribution, metabolism, and excretion (ADME).
3. Pharmacodynamics (PD) Understanding the drugs biological effects and mechanism of action.
4. Dose Escalation and Determination Establishing the optimal dosage for further trials.
These trials are usually open-label (no placebo control) and can be conducted in different designs, such as single ascending dose (SAD), multiple ascending dose (MAD), and food effect studies. While most drugs fail in this phase due to safety concerns, successful candidates proceed to Phase 2 trials, where efficacy is further evaluated.
2024 Trend Updates: What Really Works In SEO & Content MarketingSearch Engine Journal
油
The future of SEO is trending toward a more human-first and user-centric approach, powered by AI intelligence and collaboration. Are you ready?
Watch as we explore which SEO trends to prioritize to achieve sustainable growth and deliver reliable results. Well dive into best practices to adapt your strategy around industry-wide disruptions like SGE, how to navigate the top challenges SEO professionals are facing, and proven tactics for prioritizing quality and building trust.
Youll hear:
- The top SEO trends to prioritize in 2024 to achieve long-term success.
- Predictions for SGEs impact, and how to adapt.
- What E-E-A-T really means, and how to implement it holistically (hint: its never been more important).
With Zack Kadish and Alex Carchietta, well show you which SEO trends to ignore and which to focus on, along with the solution to overcoming rapid, significant and disruptive Google algorithm updates.
If youre looking to cut through the noise of constant SEO and content trends to drive success, you wont want to miss this webinar.
Storytelling For The Web: Integrate Storytelling in your Design ProcessChiara Aliotta
油
In this slides I explain how I have used storytelling techniques to elevate websites and brands and create memorable user experiences. You can discover practical tips as I showcase the elements of good storytelling and its applied to some examples of diverse brands/projects..
Drugs acting on Respiratory System: Anti-Athmatic Drugs.pptxSivaGanesh552177
油
The topic " Anti-Asthmatic Drugs" is covered under Unit I of the Pharmacology of Drugs Acting on the Respiratory System, which is included in the course of Pharmacology III with course code BP602.
Learning Objectives:
1. Explain the basis of Nernst potential and its importance in generation of resting membrane potential
2. Comprehend different mechanisms responsible for the genesis of membrane potential
3. Use the Goldman equation to explain how the relative permeability of the ions create a resting membrane potential
Understanding the Impact of Revalidation on UK Healthcare Professionals.pdfMedical Apprisal
油
Revalidation UK is a vital process ensuring healthcare professionals maintain high standards, enhancing patient safety and public trust. This mandatory assessment promotes continuous professional development, requiring practitioners to demonstrate competence, adhere to ethical guidelines, and engage in reflective practice. Despite challenges like administrative burdens and balancing clinical duties, revalidation fosters lifelong learning and accountability. Employers and regulatory bodies play a key role in supporting professionals through training, mentorship, and streamlined appraisal processes. As technology advances, revalidation UK will evolve to simplify compliance and enhance accessibility. By embracing revalidation, healthcare professionals contribute to a safer, more effective healthcare system, reinforcing trust and excellence in patient care across the UK.
Classification of Selective Alpha Agonists Based on Generation
Selective alpha agonists can be classified into first-generation, second-generation, and third-generation based on their pharmacological properties, receptor specificity, and clinical applications.
1. First-Generation Selective Alpha Agonists
(Non-subtype selective, older agents, higher side effects)
These drugs act on 留1 or 留2 receptors but with lower specificity and more systemic side effects.
Selective 留1 Agonists (Vasoconstrictors, Hypotension Treatment)
Methoxamine Used to treat hypotension.
Phenylephrine Used as a nasal decongestant and to increase blood pressure.
Midodrine Used for orthostatic hypotension.
Metaraminol Used in hypotensive states and shock.
Selective 留2 Agonists (Centrally Acting, Anti-Hypertensive Drugs)
Clonidine Used for hypertension, ADHD, and withdrawal syndromes.
Methyldopa Used for hypertension, especially in pregnancy.
Guanfacine Used in hypertension and ADHD.
2. Second-Generation Selective Alpha Agonists
(More receptor selectivity, improved safety profile, fewer side effects)
Selective 留1 Agonists (Longer Duration, Specific Targeting)
Amidephrine Used in hypotension.
Selective 留2 Agonists (Better CNS Penetration, Neurological Uses)
Brimonidine Used in glaucoma (reduces intraocular pressure).
Apraclonidine Used in short-term treatment of glaucoma.
Tizanidine Used as a muscle relaxant in spasticity.
Lofexidine Used in opioid withdrawal treatment.
3. Third-Generation Selective Alpha Agonists
(Highly selective, fewer side effects, newer therapeutic applications)
Selective 留2 Agonists (High Selectivity, Novel Applications)
Dexmedetomidine Used as a sedative in ICU and anesthesia.
Medetomidine Used in veterinary anesthesia.
Fadolmidine Investigated for pain relief with fewer cardiovascular effects.
Detomidine Used in veterinary medicine for sedation
Classification of Selective Beta Agonists Based on Generation
Selective 硫-adrenergic agonists can be classified into three generations based on their receptor selectivity, duration of action, and therapeutic advancements.
1. First-Generation Selective Beta Agonists
(Non-specific, Short-acting, Higher Side Effects)
Early 硫-agonists with partial selectivity, often affecting both 硫1 and 硫2 receptors.
Shorter duration of action, leading to frequent dosing requirements.
Key Drugs:
Isoproterenol A non-selective 硫1 and 硫2 agonist, used for bradycardia and heart block.
Dobutamine A selective 硫1 agonist, used in acute heart failure and cardiogenic shock.
Ritodrine A selective 硫2 agonist, previously used for delaying preterm labor.
2. Second-Generation Selective Beta Agonists
(More Selective, Longer Duration, Improved Safety)
These drugs show improved selectivity for either 硫1 or 硫2 receptors, reducing unwanted cardiac effects.
Longer-acting compared to first-generation.
Selective 硫1 Agonists (Primarily Cardiac Stimulants)
Denopamine Used in heart failure treatment.
Prenalte
The title "Nasal Decongestants and Respiratory Stimulants" is covered under Unit I of the Pharmacology of drugs acting on the Respiratory System, which is included in the course of Pharmacology III with course code BP602.
Drugs acting on Respiratory System: Expectorants and Antitussives.pptxSivaGanesh552177
油
The topic "Expectorants and Antitussives" is covered under Unit I of the Pharmacology of drugs acting on the Respiratory System, which is included in the course of Pharmacology III with course code BP602
PARKINSONS USMLE style question by dr ankush goyalDr Ankush goyal
油
Parkinsonism refers to a clinical syndrome characterized by a combination of motor and non-motor symptoms that resemble Parkinsons disease (PD). It results from dysfunction in the basal ganglia, particularly due to dopamine deficiency in the substantia nigra.
Key Features of Parkinsonism:
1. Bradykinesia Slowness of movement with difficulty in initiating and executing voluntary movements.
2. Rigidity Increased muscle tone, presenting as either:
Lead-pipe rigidity (uniform resistance)
Cogwheel rigidity (intermittent resistance with a ratchet-like quality)
3. Tremor Resting tremor, typically "pill-rolling" (4-6 Hz), that improves with movement.
4. Postural Instability Impaired balance leading to a higher risk of falls.
Causes of Parkinsonism:
1. Idiopathic Parkinsons Disease (PD) The most common cause, due to progressive degeneration of dopaminergic neurons in the substantia nigra.
2. Drug-Induced Parkinsonism Caused by dopamine-blocking agents (e.g., antipsychotics, metoclopramide, reserpine).
3. Atypical Parkinsonian Syndromes (Parkinson-plus syndromes) Progressive conditions with additional features beyond classic Parkinsonism, such as:
Multiple System Atrophy (MSA)
Progressive Supranuclear Palsy (PSP)
Corticobasal Degeneration (CBD)
Dementia with Lewy Bodies (DLB)
4. Vascular Parkinsonism Due to multiple small strokes affecting the basal ganglia.
5. Toxic or Metabolic Causes Includes manganese poisoning, carbon monoxide exposure, Wilsons disease.
6. Post-Encephalitic Parkinsonism Rare, seen in survivors of encephalitis lethargica.
Diagnosis:
Clinical Evaluation Based on cardinal motor symptoms.
Response to Levodopa Helps differentiate PD from other causes.
Neuroimaging (MRI, DaTscan) Useful in atypical cases.
Management:
Pharmacological Treatment:
Levodopa (with carbidopa)
Dopamine agonists (pramipexole, ropinirole)
MAO-B inhibitors (selegiline, rasagiline)
COMT inhibitors (entacapone)
Anticholinergics (for tremors)
Non-Pharmacological Treatment:
Physiotherapy, speech therapy
Deep Brain Stimulation (DBS) in selected cases
### **Acyclovir and Anti-Herpes Medications**
**Acyclovir** is an antiviral medication used to treat infections caused by herpes viruses, including:
- **Herpes simplex virus (HSV-1 & HSV-2)** Causes cold sores and genital herpes.
- **Varicella-zoster virus (VZV)** Causes chickenpox and shingles.
### **Mechanism of Action:**
Acyclovir works by inhibiting viral DNA replication. It is activated inside virus-infected cells, where it blocks viral enzymes, preventing the virus from multiplying.
### **Forms & Dosage:**
- **Oral (Tablets/Capsules/Liquid)** Used for mild to moderate infections.
- **Topical (Cream/Ointment)** For cold sores and mild skin infections.
- **Intravenous (IV)** For severe infections like herpes encephalitis.
### **Other Anti-Herpes Medications:**
- **Valacyclovir (Valtrex)** A prodrug of acyclovir with better absorption.
- **Famciclovir (Famvir)** Another antiviral with a longer duration of action.
- **Penciclovir (Denavir)** Used topically for herpes labialis (cold sores).
### **Uses:**
- Treats and manages outbreaks of herpes simplex.
- Reduces the severity and duration of symptoms.
- Used for long-term suppression to prevent recurrent infections.
- Helps in managing shingles and chickenpox.
### **Side Effects:**
- Nausea, vomiting, diarrhea.
- Headache, dizziness, fatigue.
- Rare: Kidney issues, allergic reactions.
### **Precautions:**
- Drink plenty of fluids to prevent kidney issues.
- Not a cure, but helps manage symptoms.
- Safe for most patients but should be used cautiously in people with kidney disease or weakened immune systems.
We all know that malaria is an infectious disease spread by mosquitos. Female Anopheles mosquitos spread the infection, a microorganism called a plasmodium, when taking a blood meal. But as the quotation often attributed to Mark Twain says What gets us into trouble is not what we dont know. Its what we know for sure that just aint so.
Like most residents of western Europe I thought little about Malaria until I had opportunity to travel to Africa. My destination in Southern Botswana was not on the malaria map. However, parts of the North of the country to which I intended to travel were. People told me I needed to get malaria tablets that had to be taken for a week or two in advance, then daily or weekly and for some time after leaving malaria areas. There were a few different medications and combination tablets available and I investigated which would be the lesser evil. None seemed particularly effective so I decided to check the evidence of the mosquito cause of malaria and how these tablets were supposed to act. I soon became suspicious of the complicated malaria transmission story.
I have written a book 'Malaria is Spread by Mosquitos?'.
This presentation is a short introduction to the topic. see https://usmalaria.com/
Chair, Eleonora Lad, MD, PhD, discusses geographic atrophy in this CME/COPE/IPCE activity titled Improving the Patient Experience in Geographic Atrophy: Are You Putting the Latest Advances Into Practice?. For the full presentation, downloadable Practice Aids, and complete CME/COPE/IPCE information, and to apply for credit, please visit us at https://bit.ly/49lZvbL. CME/COPE/IPCE credit will be available until March 20, 2026.
Let's Talk About It: Gynecologic Cancer (Calm Body, Calm Mind - Using Your Bo...RheannaRandazzo
油
Stress manifests in our thinking, emotions, and bodies. Recognizing those signs and building skills to address stress takes attention and effort. Cultivating skills to use your body as a tool to help you find calm and regain a sense of control can help you navigate moments of heightened anxiety. Join us on Wednesday, March 12th, to learn strategies for quieting your body and, thereby, calming your mind. Lets Talk About It.
TRAGEDIES IN PHASE 1 CLINICAL TRIAL Dr ankush goyalDr Ankush goyal
油
Phase 1 Clinical Trials: An Overview
Phase 1 clinical trials are the first stage of testing a new drug or treatment in humans. These trials primarily assess the safety, tolerability, pharmacokinetics, and pharmacodynamics of the investigational drug. Conducted on a small group of healthy volunteers (typically 20100) or, in certain cases, patients with the target disease, Phase 1 trials aim to determine:
1. Safety and Tolerability Identifying potential side effects and the maximum tolerated dose.
2. Pharmacokinetics (PK) Studying drug absorption, distribution, metabolism, and excretion (ADME).
3. Pharmacodynamics (PD) Understanding the drugs biological effects and mechanism of action.
4. Dose Escalation and Determination Establishing the optimal dosage for further trials.
These trials are usually open-label (no placebo control) and can be conducted in different designs, such as single ascending dose (SAD), multiple ascending dose (MAD), and food effect studies. While most drugs fail in this phase due to safety concerns, successful candidates proceed to Phase 2 trials, where efficacy is further evaluated.
2024 Trend Updates: What Really Works In SEO & Content MarketingSearch Engine Journal
油
The future of SEO is trending toward a more human-first and user-centric approach, powered by AI intelligence and collaboration. Are you ready?
Watch as we explore which SEO trends to prioritize to achieve sustainable growth and deliver reliable results. Well dive into best practices to adapt your strategy around industry-wide disruptions like SGE, how to navigate the top challenges SEO professionals are facing, and proven tactics for prioritizing quality and building trust.
Youll hear:
- The top SEO trends to prioritize in 2024 to achieve long-term success.
- Predictions for SGEs impact, and how to adapt.
- What E-E-A-T really means, and how to implement it holistically (hint: its never been more important).
With Zack Kadish and Alex Carchietta, well show you which SEO trends to ignore and which to focus on, along with the solution to overcoming rapid, significant and disruptive Google algorithm updates.
If youre looking to cut through the noise of constant SEO and content trends to drive success, you wont want to miss this webinar.
Storytelling For The Web: Integrate Storytelling in your Design ProcessChiara Aliotta
油
In this slides I explain how I have used storytelling techniques to elevate websites and brands and create memorable user experiences. You can discover practical tips as I showcase the elements of good storytelling and its applied to some examples of diverse brands/projects..
This presentation by Thibault Schrepel, Associate Professor of Law at Vrije Universiteit Amsterdam University, was made during the discussion Artificial Intelligence, Data and Competition held at the 143rd meeting of the OECD Competition Committee on 12 June 2024. More papers and presentations on the topic can be found at oe.cd/aicomp.
This presentation was uploaded with the authors consent.
How to Leverage AI to Boost Employee Wellness - Lydia Di Francesco - SocialHR...SocialHRCamp
油
Speaker: Lydia Di Francesco
In this workshop, participants will delve into the realm of AI and its profound potential to revolutionize employee wellness initiatives. From stress management to fostering work-life harmony, AI offers a myriad of innovative tools and strategies that can significantly enhance the wellbeing of employees in any organization. Attendees will learn how to effectively leverage AI technologies to cultivate a healthier, happier, and more productive workforce. Whether it's utilizing AI-powered chatbots for mental health support, implementing data analytics to identify internal, systemic risk factors, or deploying personalized wellness apps, this workshop will equip participants with actionable insights and best practices to harness the power of AI for boosting employee wellness. Join us and discover how AI can be a strategic partner towards a culture of wellbeing and resilience in the workplace.
2024 State of Marketing Report by HubspotMarius Sescu
油
https://www.hubspot.com/state-of-marketing
揃 Scaling relationships and proving ROI
揃 Social media is the place for search, sales, and service
揃 Authentic influencer partnerships fuel brand growth
揃 The strongest connections happen via call, click, chat, and camera.
揃 Time saved with AI leads to more creative work
揃 Seeking: A single source of truth
揃 TLDR; Get on social, try AI, and align your systems.
揃 More human marketing, powered by robots
ChatGPT is a revolutionary addition to the world since its introduction in 2022. A big shift in the sector of information gathering and processing happened because of this chatbot. What is the story of ChatGPT? How is the bot responding to prompts and generating contents? Swipe through these slides prepared by Expeed Software, a web development company regarding the development and technical intricacies of ChatGPT!
Product Design Trends in 2024 | Teenage EngineeringsPixeldarts
油
The realm of product design is a constantly changing environment where technology and style intersect. Every year introduces fresh challenges and exciting trends that mold the future of this captivating art form. In this piece, we delve into the significant trends set to influence the look and functionality of product design in the year 2024.
How Race, Age and Gender Shape Attitudes Towards Mental HealthThinkNow
油
Mental health has been in the news quite a bit lately. Dozens of U.S. states are currently suing Meta for contributing to the youth mental health crisis by inserting addictive features into their products, while the U.S. Surgeon General is touring the nation to bring awareness to the growing epidemic of loneliness and isolation. The country has endured periods of low national morale, such as in the 1970s when high inflation and the energy crisis worsened public sentiment following the Vietnam War. The current mood, however, feels different. Gallup recently reported that national mental health is at an all-time low, with few bright spots to lift spirits.
To better understand how Americans are feeling and their attitudes towards mental health in general, ThinkNow conducted a nationally representative quantitative survey of 1,500 respondents and found some interesting differences among ethnic, age and gender groups.
Technology
For example, 52% agree that technology and social media have a negative impact on mental health, but when broken out by race, 61% of Whites felt technology had a negative effect, and only 48% of Hispanics thought it did.
While technology has helped us keep in touch with friends and family in faraway places, it appears to have degraded our ability to connect in person. Staying connected online is a double-edged sword since the same news feed that brings us pictures of the grandkids and fluffy kittens also feeds us news about the wars in Israel and Ukraine, the dysfunction in Washington, the latest mass shooting and the climate crisis.
Hispanics may have a built-in defense against the isolation technology breeds, owing to their large, multigenerational households, strong social support systems, and tendency to use social media to stay connected with relatives abroad.
Age and Gender
When asked how individuals rate their mental health, men rate it higher than women by 11 percentage points, and Baby Boomers rank it highest at 83%, saying its good or excellent vs. 57% of Gen Z saying the same.
Gen Z spends the most amount of time on social media, so the notion that social media negatively affects mental health appears to be correlated. Unfortunately, Gen Z is also the generation thats least comfortable discussing mental health concerns with healthcare professionals. Only 40% of them state theyre comfortable discussing their issues with a professional compared to 60% of Millennials and 65% of Boomers.
Race Affects Attitudes
As seen in previous research conducted by ThinkNow, Asian Americans lag other groups when it comes to awareness of mental health issues. Twenty-four percent of Asian Americans believe that having a mental health issue is a sign of weakness compared to the 16% average for all groups. Asians are also considerably less likely to be aware of mental health services in their communities (42% vs. 55%) and most likely to seek out information on social media (51% vs. 35%).
AI Trends in Creative Operations 2024 by Artwork Flow.pdfmarketingartwork
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Creative operations teams expect increased AI use in 2024. Currently, over half of tasks are not AI-enabled, but this is expected to decrease in the coming year. ChatGPT is the most popular AI tool currently. Business leaders are more actively exploring AI benefits than individual contributors. Most respondents do not believe AI will impact workforce size in 2024. However, some inhibitions still exist around AI accuracy and lack of understanding. Creatives primarily want to use AI to save time on mundane tasks and boost productivity.
Organizational culture includes values, norms, systems, symbols, language, assumptions, beliefs, and habits that influence employee behaviors and how people interpret those behaviors. It is important because culture can help or hinder a company's success. Some key aspects of Netflix's culture that help it achieve results include hiring smartly so every position has stars, focusing on attitude over just aptitude, and having a strict policy against peacocks, whiners, and jerks.
PEPSICO Presentation to CAGNY Conference Feb 2024Neil Kimberley
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PepsiCo provided a safe harbor statement noting that any forward-looking statements are based on currently available information and are subject to risks and uncertainties. It also provided information on non-GAAP measures and directing readers to its website for disclosure and reconciliation. The document then discussed PepsiCo's business overview, including that it is a global beverage and convenient food company with iconic brands, $91 billion in net revenue in 2023, and nearly $14 billion in core operating profit. It operates through a divisional structure with a focus on local consumers.
Content Methodology: A Best Practices Report (Webinar)contently
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This document provides an overview of content methodology best practices. It defines content methodology as establishing objectives, KPIs, and a culture of continuous learning and iteration. An effective methodology focuses on connecting with audiences, creating optimal content, and optimizing processes. It also discusses why a methodology is needed due to the competitive landscape, proliferation of channels, and opportunities for improvement. Components of an effective methodology include defining objectives and KPIs, audience analysis, identifying opportunities, and evaluating resources. The document concludes with recommendations around creating a content plan, testing and optimizing content over 90 days.
How to Prepare For a Successful Job Search for 2024Albert Qian
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The document provides guidance on preparing a job search for 2024. It discusses the state of the job market, focusing on growth in AI and healthcare but also continued layoffs. It recommends figuring out what you want to do by researching interests and skills, then conducting informational interviews. The job search should involve building a personal brand on LinkedIn, actively applying to jobs, tailoring resumes and interviews, maintaining job hunting as a habit, and continuing self-improvement. Once hired, the document advises setting new goals and keeping skills and networking active in case of future opportunities.
A report by thenetworkone and Kurio.
The contributing experts and agencies are (in an alphabetical order): Sylwia Rytel, Social Media Supervisor, 180heartbeats + JUNG v MATT (PL), Sharlene Jenner, Vice President - Director of Engagement Strategy, Abelson Taylor (USA), Alex Casanovas, Digital Director, Atrevia (ES), Dora Beilin, Senior Social Strategist, Barrett Hoffher (USA), Min Seo, Campaign Director, Brand New Agency (KR), Desh辿 M. Gully, Associate Strategist, Day One Agency (USA), Francesca Trevisan, Strategist, Different (IT), Trevor Crossman, CX and Digital Transformation Director; Olivia Hussey, Strategic Planner; Simi Srinarula, Social Media Manager, The Hallway (AUS), James Hebbert, Managing Director, Hylink (CN / UK), Mundy lvarez, Planning Director; Pedro Rojas, Social Media Manager; Pancho Gonz叩lez, CCO, Inbrax (CH), Oana Oprea, Head of Digital Planning, Jam Session Agency (RO), Amy Bottrill, Social Account Director, Launch (UK), Gaby Arriaga, Founder, Leonardo1452 (MX), Shantesh S Row, Creative Director, Liwa (UAE), Rajesh Mehta, Chief Strategy Officer; Dhruv Gaur, Digital Planning Lead; Leonie Mergulhao, Account Supervisor - Social Media & PR, Medulla (IN), Aurelija Plioplyt, Head of Digital & Social, Not Perfect (LI), Daiana Khaidargaliyeva, Account Manager, Osaka Labs (UK / USA), Stefanie Sohnchen, Vice President Digital, PIABO Communications (DE), Elisabeth Winiartati, Managing Consultant, Head of Global Integrated Communications; Lydia Aprina, Account Manager, Integrated Marketing and Communications; Nita Prabowo, Account Manager, Integrated Marketing and Communications; Okhi, Web Developer, PNTR Group (ID), Kei Obusan, Insights Director; Daffi Ranandi, Insights Manager, Radarr (SG), Gautam Reghunath, Co-founder & CEO, Talented (IN), Donagh Humphreys, Head of Social and Digital Innovation, THINKHOUSE (IRE), Sarah Yim, Strategy Director, Zulu Alpha Kilo (CA).
Trends In Paid Search: Navigating The Digital Landscape In 2024Search Engine Journal
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The search marketing landscape is evolving rapidly with new technologies, and professionals, like you, rely on innovative paid search strategies to meet changing demands.
Its important that youre ready to implement new strategies in 2024.
Check this out and learn the top trends in paid search advertising that are expected to gain traction, so you can drive higher ROI more efficiently in 2024.
Youll learn:
- The latest trends in AI and automation, and what this means for an evolving paid search ecosystem.
- New developments in privacy and data regulation.
- Emerging ad formats that are expected to make an impact next year.
Watch Sreekant Lanka from iQuanti and Irina Klein from OneMain Financial as they dive into the future of paid search and explore the trends, strategies, and technologies that will shape the search marketing landscape.
If youre looking to assess your paid search strategy and design an industry-aligned plan for 2024, then this webinar is for you.
5 Public speaking tips from TED - Visualized summarySpeakerHub
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From their humble beginnings in 1984, TED has grown into the worlds most powerful amplifier for speakers and thought-leaders to share their ideas. They have over 2,400 filmed talks (not including the 30,000+ TEDx videos) freely available online, and have hosted over 17,500 events around the world.
With over one billion views in a year, its no wonder that so many speakers are looking to TED for ideas on how to share their message more effectively.
The article 5 Public-Speaking Tips TED Gives Its Speakers, by Carmine Gallo for Forbes, gives speakers five practical ways to connect with their audience, and effectively share their ideas on stage.
Whether you are gearing up to get on a TED stage yourself, or just want to master the skills that so many of their speakers possess, these tips and quotes from Chris Anderson, the TED Talks Curator, will encourage you to make the most impactful impression on your audience.
See the full article and more summaries like this on SpeakerHub here: https://speakerhub.com/blog/5-presentation-tips-ted-gives-its-speakers
See the original article on Forbes here:
http://www.forbes.com/forbes/welcome/?toURL=http://www.forbes.com/sites/carminegallo/2016/05/06/5-public-speaking-tips-ted-gives-its-speakers/&refURL=&referrer=#5c07a8221d9b
ChatGPT and the Future of Work - Clark Boyd Clark Boyd
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Everyone is in agreement that ChatGPT (and other generative AI tools) will shape the future of work. Yet there is little consensus on exactly how, when, and to what extent this technology will change our world.
Businesses that extract maximum value from ChatGPT will use it as a collaborative tool for everything from brainstorming to technical maintenance.
For individuals, now is the time to pinpoint the skills the future professional will need to thrive in the AI age.
Check out this presentation to understand what ChatGPT is, how it will shape the future of work, and how you can prepare to take advantage.
The document provides career advice for getting into the tech field, including:
- Doing projects and internships in college to build a portfolio.
- Learning about different roles and technologies through industry research.
- Contributing to open source projects to build experience and network.
- Developing a personal brand through a website and social media presence.
- Networking through events, communities, and finding a mentor.
- Practicing interviews through mock interviews and whiteboarding coding questions.
Google's Just Not That Into You: Understanding Core Updates & Search IntentLily Ray
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1. Core updates from Google periodically change how its algorithms assess and rank websites and pages. This can impact rankings through shifts in user intent, site quality issues being caught up to, world events influencing queries, and overhauls to search like the E-A-T framework.
2. There are many possible user intents beyond just transactional, navigational and informational. Identifying intent shifts is important during core updates. Sites may need to optimize for new intents through different content types and sections.
3. Responding effectively to core updates requires analyzing "before and after" data to understand changes, identifying new intents or page types, and ensuring content matches appropriate intents across video, images, knowledge graphs and more.