A metallurgical engineer with over 30 years of experience managing production, quality, research and development at various materials manufacturing companies. He has led teams to meet challenges and improve bottom line performance through problem identification, innovation, and statistical process improvement methods.
CD8+ T cells from asymptomatic HLA-A*02:01-positive individuals with herpes simplex virus type 1 preferentially recognize epitopes from the glycoprotein B protein. These epitopes induced polyfunctional T cell responses including cytotoxic activity and cytokine production. In contrast, symptomatic individuals recognized different glycoprotein B epitopes and their T cell responses were mainly monofunctional. Immunizing a mouse model with asymptomatic epitopes induced protective immunity against ocular herpes, while symptomatic epitopes did not. This suggests distinct human T cell epitopes are recognized in asymptomatic versus symptomatic individuals.
Infection with a host-range mutant adenovirus 5 (Ad5hr) in rhesus macaques induced both innate and adaptive immune responses. There was a delayed increase in plasmacytoid dendritic cells and their interferon-alpha production in blood 2-6 weeks after infection. Ad5hr infection also transiently increased the frequencies of regulatory T cells and activated/proliferating CD4+ T cells in blood. Expression of proinflammatory cytokines like IFN-gamma, IL-1, CCL20 and TNF in blood was suppressed after Ad5hr infection. Ad5hr induced polyfunctional CD4+ and CD8+ T cell responses specific to the adenovirus hexon protein in all
This short document promotes creating presentations using Haiku Deck, a tool for making slideshows. It encourages the reader to get started making their own Haiku Deck presentation and sharing it on 際際滷Share. In a single sentence, it pitches the idea of using Haiku Deck to easily create and publish online presentations.
Dokumen ini membahas tentang virtualisasi dan paravirtualisasi. Virtualisasi penuh atau full virtualization mengubah seluruh sistem komputer menjadi konstruksi perangkat lunak yang berfungsi sebagai perangkat keras. Paravirtualisasi lebih mudah diimplementasikan dibandingkan virtualisasi penuh dan hanya menyediakan simulasi sebagian perangkat keras. Contoh hypervisor virtualisasi penuh adalah VMware, VirtualBox, QEMU, dan KVM, sedangkan contoh paravirtual
Ryan Jay is an experienced freelance audio mixer and sound recordist with over 10 years of experience in professional audio production. He owns and operates Recall Sound Production, providing location sound recording, audio mixing, and post production services for film, television, live events and corporate clients. His resume highlights his audio equipment, software skills, and experience in live and studio recording, sound design, and working on a variety of productions.
The report summarizes the findings of consultations conducted in 9 ASEAN countries on their school safety programs as part of the ASEAN Safe Schools Initiative Phase 1. It was found that while all countries have policies on disaster management and climate change adaptation, there is a lack of common standards and guidelines for safe schools. Recommendations include developing a common guide for vulnerability assessments, improving coordination between government departments, and ensuring programs are inclusive of vulnerable children. The report aims to inform future initiatives to strengthen school safety in the ASEAN region.
The study aimed to recapitulate key findings from the Phase IIb Step Trial of a Merck Ad5 HIV-1 vaccine in rhesus macaques. Rhesus macaques were infected with Ad5hr and immunized with an Ad5 SIV vaccine or empty vector. They were then challenged with escalating doses of penile SIV exposure. The Ad5 SIV vaccine induced CD8+ T cell responses in 70% of monkeys, similar to humans in the Step Trial, but did not protect against SIV infection. At the lowest SIV dose, 2/9 Ad5-seropositive monkeys immunized with the Ad5 SIV vaccine became infected compared to 0/34 in
El documento proporciona una introducci坦n al an叩lisis de estados financieros. Define el an叩lisis financiero como el proceso de evaluar la posici坦n financiera y resultados operativos de una empresa para establecer estimaciones sobre las condiciones y resultados futuros. Explica que el an叩lisis financiero ayuda a los ejecutivos a determinar si las decisiones de financiamiento fueron adecuadas y a predecir el futuro de las inversiones de la organizaci坦n. Adem叩s, describe los principales estados financieros, m辿todos de an叩lisis e 鱈ndices financ
Ryan Jay is an experienced freelance audio mixer and sound recordist with over 10 years of experience in professional audio production. He owns and operates Recall Sound Production, providing location sound recording, audio mixing, and post production services for film, television, live events and corporate clients. His resume highlights his audio equipment, software skills, and experience in live and studio recording, sound design, and working on a variety of productions.
The report summarizes the findings of consultations conducted in 9 ASEAN countries on their school safety programs as part of the ASEAN Safe Schools Initiative Phase 1. It was found that while all countries have policies on disaster management and climate change adaptation, there is a lack of common standards and guidelines for safe schools. Recommendations include developing a common guide for vulnerability assessments, improving coordination between government departments, and ensuring programs are inclusive of vulnerable children. The report aims to inform future initiatives to strengthen school safety in the ASEAN region.
The study aimed to recapitulate key findings from the Phase IIb Step Trial of a Merck Ad5 HIV-1 vaccine in rhesus macaques. Rhesus macaques were infected with Ad5hr and immunized with an Ad5 SIV vaccine or empty vector. They were then challenged with escalating doses of penile SIV exposure. The Ad5 SIV vaccine induced CD8+ T cell responses in 70% of monkeys, similar to humans in the Step Trial, but did not protect against SIV infection. At the lowest SIV dose, 2/9 Ad5-seropositive monkeys immunized with the Ad5 SIV vaccine became infected compared to 0/34 in
El documento proporciona una introducci坦n al an叩lisis de estados financieros. Define el an叩lisis financiero como el proceso de evaluar la posici坦n financiera y resultados operativos de una empresa para establecer estimaciones sobre las condiciones y resultados futuros. Explica que el an叩lisis financiero ayuda a los ejecutivos a determinar si las decisiones de financiamiento fueron adecuadas y a predecir el futuro de las inversiones de la organizaci坦n. Adem叩s, describe los principales estados financieros, m辿todos de an叩lisis e 鱈ndices financ