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ib biology biology ahl hl ib topic 4.2 energy flow topic 11.3 kidney osmoregulation new syllabus energy ecology protein synthesis central dogma topic 7.3 translation histones epigenetics gene expression transcription editable dna structure dna question set assessment statements hormones and metabolism option d5 d5 metabolism option d hormones sarcomere muscles topic 11.2 movement assessment cell respiration 8.2 genetics 3.3 meiosis meiosis topic 3.3 4.2 energy flow ecosystems dna replication