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cpb hole in heart lung carcinoma lung tof thoracotomy septum atrial septal defect asd tricuspid valve ventricle right atrium anatomy heart ttf1 pneumonia carcimona pathology gross specimen spell cyanosis cyanotic congential heart disease pulmonary cancer aha/acc ctvs hocm myocardial protection impella iabp mcs mechanical circulatory support carcinoma lung group a streptococus arf acute rheumatic fever ventricular septal defect vsd cyanotic heart disease fallot physiology deformities tomours chest wall cardiogenic shock mods shock valve mitral stenosis rheumatic heart disease mitral valve arrythmias heart rhythum ecg lung surgeries thoracic incisions aorta