Charlesworth runs her own practice conducting speculative design projects, often collaborating with scientists, futurists, designers and academics including think tanks Foresight (UK) and the Institute for the Future (US). Alongside design collaborator Marei Wollersberger she recently exhibited a range of hypothetical scenarios and prototypes entitled Citizen Evolution:The Future of Vienna at the MAKVienna in Austria, which has now become part of their permanent collection. With this interdisciplinary approach she explores alternative futures that new technologies and science may hold.