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cancer presentation medicine student smoking cessation physiology high altitude pulmonary edema altitude physiology pht cor pulmonale pulmonary hypertension lung malignancy hepatic failure renal failure antibiotics asbestosis pleura asbestos education pneumonia invasive pulmonary aspergillosis neurogenic pulmonary edema osa obstructive sleep apnea poland syndrome pectus excavatum pectus carinatum scoliosis ankylosing spondylitis interstitial lung disease ild ventilation perfusion vq sepsis malignancy mpe malignant pleural effusion ciggarate