ºÝºÝߣshows by User: GERSTELPresentations / http://www.slideshare.net/images/logo.gif ºÝºÝߣshows by User: GERSTELPresentations / Thu, 01 Jun 2017 15:24:46 GMT ºÝºÝߣShare feed for ºÝºÝߣshows by User: GERSTELPresentations Automated sample preparation using the GERSTEL MPS Series and MAESTRO software, prior to injection into an LC or LC-QQQ system /slideshow/automated-sample-preparation-using-the-gerstel-mps-series-and-maestro-software-prior-to-injection-into-an-lc-or-lcqqq-system/76564630 053117fdfautomatedsampleprepforlcmsms-170601152446
During This Free Presentation, You Will Learn: How the GERSTEL MPS and MAESTRO software can be used to automate a variety of sample preparation techniques as well as injection of samples. Specific applications that use automated sample preparation prior to injection into an LCMSMS system. The wide variety of automated sample preparation options offered by GERSTEL. Automated Dried Blood Spot extraction and analysis using LC/MS/MS. Automated Liquid-Liquid extraction and analysis by LC/MS/MS of vitamin B compounds from fortified drinks. Automated SPE of drugs of abuse from oral fluid samples and analysis by LC/MS/MS.]]>

During This Free Presentation, You Will Learn: How the GERSTEL MPS and MAESTRO software can be used to automate a variety of sample preparation techniques as well as injection of samples. Specific applications that use automated sample preparation prior to injection into an LCMSMS system. The wide variety of automated sample preparation options offered by GERSTEL. Automated Dried Blood Spot extraction and analysis using LC/MS/MS. Automated Liquid-Liquid extraction and analysis by LC/MS/MS of vitamin B compounds from fortified drinks. Automated SPE of drugs of abuse from oral fluid samples and analysis by LC/MS/MS.]]>
Thu, 01 Jun 2017 15:24:46 GMT /slideshow/automated-sample-preparation-using-the-gerstel-mps-series-and-maestro-software-prior-to-injection-into-an-lc-or-lcqqq-system/76564630 GERSTELPresentations@slideshare.net(GERSTELPresentations) Automated sample preparation using the GERSTEL MPS Series and MAESTRO software, prior to injection into an LC or LC-QQQ system GERSTELPresentations During This Free Presentation, You Will Learn: How the GERSTEL MPS and MAESTRO software can be used to automate a variety of sample preparation techniques as well as injection of samples. Specific applications that use automated sample preparation prior to injection into an LCMSMS system. The wide variety of automated sample preparation options offered by GERSTEL. Automated Dried Blood Spot extraction and analysis using LC/MS/MS. Automated Liquid-Liquid extraction and analysis by LC/MS/MS of vitamin B compounds from fortified drinks. Automated SPE of drugs of abuse from oral fluid samples and analysis by LC/MS/MS. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/053117fdfautomatedsampleprepforlcmsms-170601152446-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> During This Free Presentation, You Will Learn: How the GERSTEL MPS and MAESTRO software can be used to automate a variety of sample preparation techniques as well as injection of samples. Specific applications that use automated sample preparation prior to injection into an LCMSMS system. The wide variety of automated sample preparation options offered by GERSTEL. Automated Dried Blood Spot extraction and analysis using LC/MS/MS. Automated Liquid-Liquid extraction and analysis by LC/MS/MS of vitamin B compounds from fortified drinks. Automated SPE of drugs of abuse from oral fluid samples and analysis by LC/MS/MS.
Automated sample preparation using the GERSTEL MPS Series and MAESTRO software, prior to injection into an LC or LC-QQQ system from GERSTEL
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Using Solid Phase Microextraction for Cannabis Testing /slideshow/using-solid-phase-microextraction-for-cannabis-testing/72752923 gerstelseminarfeb2017-170302211428
In the quickly changing landscape of cannabis testing, laboratories are faced with the challenge of providing accurate results for a variety of different tests on challenging matrices. The wide variety of matrices encountered, including both plants, foods, and oily extracts, have complex chemical compositions which include pigments, fats, proteins and sugars. The sample preparation methods used must provide analyses free of these interferences for accurate and robust testing. In this seminar, we will present simple and effective sample preparation and analysis methods using solid phase microextraction (SPME) for determination of residual solvents and terpenes. SPME is a solvent-less extraction technique that is quantitative, sensitive, cost effective, and easy to automate. We will describe how to use SPME to cleanly, accurately and quantitatively determine residual solvents from hemp extract and terpenes from cannabis plant material. For both applications, descriptions of the method procedure along with data showing accuracy and reproducibility will be presented. ]]>

In the quickly changing landscape of cannabis testing, laboratories are faced with the challenge of providing accurate results for a variety of different tests on challenging matrices. The wide variety of matrices encountered, including both plants, foods, and oily extracts, have complex chemical compositions which include pigments, fats, proteins and sugars. The sample preparation methods used must provide analyses free of these interferences for accurate and robust testing. In this seminar, we will present simple and effective sample preparation and analysis methods using solid phase microextraction (SPME) for determination of residual solvents and terpenes. SPME is a solvent-less extraction technique that is quantitative, sensitive, cost effective, and easy to automate. We will describe how to use SPME to cleanly, accurately and quantitatively determine residual solvents from hemp extract and terpenes from cannabis plant material. For both applications, descriptions of the method procedure along with data showing accuracy and reproducibility will be presented. ]]>
Thu, 02 Mar 2017 21:14:27 GMT /slideshow/using-solid-phase-microextraction-for-cannabis-testing/72752923 GERSTELPresentations@slideshare.net(GERSTELPresentations) Using Solid Phase Microextraction for Cannabis Testing GERSTELPresentations In the quickly changing landscape of cannabis testing, laboratories are faced with the challenge of providing accurate results for a variety of different tests on challenging matrices. The wide variety of matrices encountered, including both plants, foods, and oily extracts, have complex chemical compositions which include pigments, fats, proteins and sugars. The sample preparation methods used must provide analyses free of these interferences for accurate and robust testing. In this seminar, we will present simple and effective sample preparation and analysis methods using solid phase microextraction (SPME) for determination of residual solvents and terpenes. SPME is a solvent-less extraction technique that is quantitative, sensitive, cost effective, and easy to automate. We will describe how to use SPME to cleanly, accurately and quantitatively determine residual solvents from hemp extract and terpenes from cannabis plant material. For both applications, descriptions of the method procedure along with data showing accuracy and reproducibility will be presented. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/gerstelseminarfeb2017-170302211428-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> In the quickly changing landscape of cannabis testing, laboratories are faced with the challenge of providing accurate results for a variety of different tests on challenging matrices. The wide variety of matrices encountered, including both plants, foods, and oily extracts, have complex chemical compositions which include pigments, fats, proteins and sugars. The sample preparation methods used must provide analyses free of these interferences for accurate and robust testing. In this seminar, we will present simple and effective sample preparation and analysis methods using solid phase microextraction (SPME) for determination of residual solvents and terpenes. SPME is a solvent-less extraction technique that is quantitative, sensitive, cost effective, and easy to automate. We will describe how to use SPME to cleanly, accurately and quantitatively determine residual solvents from hemp extract and terpenes from cannabis plant material. For both applications, descriptions of the method procedure along with data showing accuracy and reproducibility will be presented.
Using Solid Phase Microextraction for Cannabis Testing from GERSTEL
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Chemical Assessment of Cannabis by GC-FID /slideshow/chemical-assessment-of-cannabis-by-gcfid/72240254 a-chemical-assessment-of-cannabis-by-gc-fid-170216181555
Throughout history, cannabis has been used as a panacea, an herbal remedy for nearly all medical concerns from simple headaches to severe pain. Now that many states have legalized medical cannabis, it is important to have analytical methodologies to study the compounds that the patients will be ingesting or inhaling. Terpenes are a major class of compounds found in cannabis. They are volatile hydrocarbons responsible for the plant’s aroma. These compounds are found in other plants as well. Through various clinical trials they were found to be medically relevant. In terms of cannabis, these compounds reportedly assist the cannabinoids in their effects. The cannabinoids bind to the cannabinoid receptor in the brain, and thus have medical relevance. Cannabichromene, cannabidiol, cannabigerol, and cannabinol are the main four cannabinoids that are implicated in relieving symptoms of pain, nausea, and directly reducing seizures. Delta-9-tetrahydrocannabinol is responsible for the euphoria experienced when smoked or ingested. With the increase in usage of cannabis due to its medical legalization in many states, it is important to have analytical methods for testing potency and variance of the cannabinoids and terpenes within the plant material. To do this, terpenes and cannabinoids were analyzed using a GC-FID. As the terpenes have higher volatility, several injection techniques were tested, including liquid injection, SPME, and headspace. The cannabinoid method was then applied to test the variance in subsequent doses of the same size, mimicking that of doses distributed to patients.]]>

Throughout history, cannabis has been used as a panacea, an herbal remedy for nearly all medical concerns from simple headaches to severe pain. Now that many states have legalized medical cannabis, it is important to have analytical methodologies to study the compounds that the patients will be ingesting or inhaling. Terpenes are a major class of compounds found in cannabis. They are volatile hydrocarbons responsible for the plant’s aroma. These compounds are found in other plants as well. Through various clinical trials they were found to be medically relevant. In terms of cannabis, these compounds reportedly assist the cannabinoids in their effects. The cannabinoids bind to the cannabinoid receptor in the brain, and thus have medical relevance. Cannabichromene, cannabidiol, cannabigerol, and cannabinol are the main four cannabinoids that are implicated in relieving symptoms of pain, nausea, and directly reducing seizures. Delta-9-tetrahydrocannabinol is responsible for the euphoria experienced when smoked or ingested. With the increase in usage of cannabis due to its medical legalization in many states, it is important to have analytical methods for testing potency and variance of the cannabinoids and terpenes within the plant material. To do this, terpenes and cannabinoids were analyzed using a GC-FID. As the terpenes have higher volatility, several injection techniques were tested, including liquid injection, SPME, and headspace. The cannabinoid method was then applied to test the variance in subsequent doses of the same size, mimicking that of doses distributed to patients.]]>
Thu, 16 Feb 2017 18:15:55 GMT /slideshow/chemical-assessment-of-cannabis-by-gcfid/72240254 GERSTELPresentations@slideshare.net(GERSTELPresentations) Chemical Assessment of Cannabis by GC-FID GERSTELPresentations Throughout history, cannabis has been used as a panacea, an herbal remedy for nearly all medical concerns from simple headaches to severe pain. Now that many states have legalized medical cannabis, it is important to have analytical methodologies to study the compounds that the patients will be ingesting or inhaling. Terpenes are a major class of compounds found in cannabis. They are volatile hydrocarbons responsible for the plant’s aroma. These compounds are found in other plants as well. Through various clinical trials they were found to be medically relevant. In terms of cannabis, these compounds reportedly assist the cannabinoids in their effects. The cannabinoids bind to the cannabinoid receptor in the brain, and thus have medical relevance. Cannabichromene, cannabidiol, cannabigerol, and cannabinol are the main four cannabinoids that are implicated in relieving symptoms of pain, nausea, and directly reducing seizures. Delta-9-tetrahydrocannabinol is responsible for the euphoria experienced when smoked or ingested. With the increase in usage of cannabis due to its medical legalization in many states, it is important to have analytical methods for testing potency and variance of the cannabinoids and terpenes within the plant material. To do this, terpenes and cannabinoids were analyzed using a GC-FID. As the terpenes have higher volatility, several injection techniques were tested, including liquid injection, SPME, and headspace. The cannabinoid method was then applied to test the variance in subsequent doses of the same size, mimicking that of doses distributed to patients. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/a-chemical-assessment-of-cannabis-by-gc-fid-170216181555-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> Throughout history, cannabis has been used as a panacea, an herbal remedy for nearly all medical concerns from simple headaches to severe pain. Now that many states have legalized medical cannabis, it is important to have analytical methodologies to study the compounds that the patients will be ingesting or inhaling. Terpenes are a major class of compounds found in cannabis. They are volatile hydrocarbons responsible for the plant’s aroma. These compounds are found in other plants as well. Through various clinical trials they were found to be medically relevant. In terms of cannabis, these compounds reportedly assist the cannabinoids in their effects. The cannabinoids bind to the cannabinoid receptor in the brain, and thus have medical relevance. Cannabichromene, cannabidiol, cannabigerol, and cannabinol are the main four cannabinoids that are implicated in relieving symptoms of pain, nausea, and directly reducing seizures. Delta-9-tetrahydrocannabinol is responsible for the euphoria experienced when smoked or ingested. With the increase in usage of cannabis due to its medical legalization in many states, it is important to have analytical methods for testing potency and variance of the cannabinoids and terpenes within the plant material. To do this, terpenes and cannabinoids were analyzed using a GC-FID. As the terpenes have higher volatility, several injection techniques were tested, including liquid injection, SPME, and headspace. The cannabinoid method was then applied to test the variance in subsequent doses of the same size, mimicking that of doses distributed to patients.
Chemical Assessment of Cannabis by GC-FID from GERSTEL
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Use of automation to achieve high performance solid phase extraction /slideshow/use-of-automation-to-achieve-high-performance-solid-phase-extraction/71970137 useofautomationtoachievehighperformancesolidphaseextraction-170209171158
Despite 40 years of SPE using LC sorbents, LC principles have been ignored due to the lack of flow control in SPE devices. Variable flow results in variation in results. Internal standards are used to achieve meaningful results. Measuring absolute recovery against external standards to demonstrate absence of matrix effect (gold standard) isn’t done. With a new SPE device, this is changed. It uses a syringe to achieve both automation & accurate flow. With GERSTEL, SPE & LC/MS/MS is automated in a single parallel workflow. van Deemter curves are measured & SPE performed at flow achieving >99% absolute recovery. As a micro device, sample dry down isn’t needed for enrichment up to 200x. SPE is performed efficiently, economically, & with performance matching all LC knowledge of the last 50 years. Examples of laboratory testing using reverse phase & ion exchange SPE are provided.]]>

Despite 40 years of SPE using LC sorbents, LC principles have been ignored due to the lack of flow control in SPE devices. Variable flow results in variation in results. Internal standards are used to achieve meaningful results. Measuring absolute recovery against external standards to demonstrate absence of matrix effect (gold standard) isn’t done. With a new SPE device, this is changed. It uses a syringe to achieve both automation & accurate flow. With GERSTEL, SPE & LC/MS/MS is automated in a single parallel workflow. van Deemter curves are measured & SPE performed at flow achieving >99% absolute recovery. As a micro device, sample dry down isn’t needed for enrichment up to 200x. SPE is performed efficiently, economically, & with performance matching all LC knowledge of the last 50 years. Examples of laboratory testing using reverse phase & ion exchange SPE are provided.]]>
Thu, 09 Feb 2017 17:11:58 GMT /slideshow/use-of-automation-to-achieve-high-performance-solid-phase-extraction/71970137 GERSTELPresentations@slideshare.net(GERSTELPresentations) Use of automation to achieve high performance solid phase extraction GERSTELPresentations Despite 40 years of SPE using LC sorbents, LC principles have been ignored due to the lack of flow control in SPE devices. Variable flow results in variation in results. Internal standards are used to achieve meaningful results. Measuring absolute recovery against external standards to demonstrate absence of matrix effect (gold standard) isn’t done. With a new SPE device, this is changed. It uses a syringe to achieve both automation & accurate flow. With GERSTEL, SPE & LC/MS/MS is automated in a single parallel workflow. van Deemter curves are measured & SPE performed at flow achieving >99% absolute recovery. As a micro device, sample dry down isn’t needed for enrichment up to 200x. SPE is performed efficiently, economically, & with performance matching all LC knowledge of the last 50 years. Examples of laboratory testing using reverse phase & ion exchange SPE are provided. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/useofautomationtoachievehighperformancesolidphaseextraction-170209171158-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> Despite 40 years of SPE using LC sorbents, LC principles have been ignored due to the lack of flow control in SPE devices. Variable flow results in variation in results. Internal standards are used to achieve meaningful results. Measuring absolute recovery against external standards to demonstrate absence of matrix effect (gold standard) isn’t done. With a new SPE device, this is changed. It uses a syringe to achieve both automation &amp; accurate flow. With GERSTEL, SPE &amp; LC/MS/MS is automated in a single parallel workflow. van Deemter curves are measured &amp; SPE performed at flow achieving &gt;99% absolute recovery. As a micro device, sample dry down isn’t needed for enrichment up to 200x. SPE is performed efficiently, economically, &amp; with performance matching all LC knowledge of the last 50 years. Examples of laboratory testing using reverse phase &amp; ion exchange SPE are provided.
Use of automation to achieve high performance solid phase extraction from GERSTEL
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https://cdn.slidesharecdn.com/profile-photo-GERSTELPresentations-48x48.jpg?cb=1523694821 Improve the analytical performance and productivity of your GC/MS- and LC/MS systems. GERSTEL delivers automated sample preparation and sample introduction solutions focused on your requirements. www.gerstelus.com https://cdn.slidesharecdn.com/ss_thumbnails/053117fdfautomatedsampleprepforlcmsms-170601152446-thumbnail.jpg?width=320&height=320&fit=bounds slideshow/automated-sample-preparation-using-the-gerstel-mps-series-and-maestro-software-prior-to-injection-into-an-lc-or-lcqqq-system/76564630 Automated sample prepa... https://cdn.slidesharecdn.com/ss_thumbnails/gerstelseminarfeb2017-170302211428-thumbnail.jpg?width=320&height=320&fit=bounds slideshow/using-solid-phase-microextraction-for-cannabis-testing/72752923 Using Solid Phase Micr... https://cdn.slidesharecdn.com/ss_thumbnails/a-chemical-assessment-of-cannabis-by-gc-fid-170216181555-thumbnail.jpg?width=320&height=320&fit=bounds slideshow/chemical-assessment-of-cannabis-by-gcfid/72240254 Chemical Assessment of...