際際滷shows by User: MarshallLevesque / http://www.slideshare.net/images/logo.gif 際際滷shows by User: MarshallLevesque / Sun, 17 Feb 2013 16:38:43 GMT 際際滷Share feed for 際際滷shows by User: MarshallLevesque Single-chromosome transcriptional profiling reveals chromosomal gene expression regulation /slideshow/singlechromosome-transcriptional-profiling-reveals-chromosomal-gene-expression-regulation/16589332 slidecast-icefish-130217163843-phpapp02
We report intron chromosomal expression FISH (iceFISH), a multiplex imaging method for measuring gene expression and chromosome structure simultaneously on single chromosomes. We find substantial differences in transcriptional frequency between genes on a translocated chromosome and the same genes in their normal chromosomal context in the same cell. Correlations between genes on a single chromosome pointed toward a cis chromosome-level transcriptional interaction spanning 14.3 megabases.]]>
We report intron chromosomal expression FISH (iceFISH), a multiplex imaging method for measuring gene expression and chromosome structure simultaneously on single chromosomes. We find substantial differences in transcriptional frequency between genes on a translocated chromosome and the same genes in their normal chromosomal context in the same cell. Correlations between genes on a single chromosome pointed toward a cis chromosome-level transcriptional interaction spanning 14.3 megabases.]]> Sun, 17 Feb 2013 16:38:43 GMT /slideshow/singlechromosome-transcriptional-profiling-reveals-chromosomal-gene-expression-regulation/16589332 MarshallLevesque@slideshare.net(MarshallLevesque) Single-chromosome transcriptional profiling reveals chromosomal gene expression regulation MarshallLevesque We report intron chromosomal expression FISH (iceFISH), a multiplex imaging method for measuring gene expression and chromosome structure simultaneously on single chromosomes. We find substantial differences in transcriptional frequency between genes on a translocated chromosome and the same genes in their normal chromosomal context in the same cell. Correlations between genes on a single chromosome pointed toward a cis chromosome-level transcriptional interaction spanning 14.3 megabases. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/slidecast-icefish-130217163843-phpapp02-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> We report intron chromosomal expression FISH (iceFISH), a multiplex imaging method for measuring gene expression and chromosome structure simultaneously on single chromosomes. We find substantial differences in transcriptional frequency between genes on a translocated chromosome and the same genes in their normal chromosomal context in the same cell. Correlations between genes on a single chromosome pointed toward a cis chromosome-level transcriptional interaction spanning 14.3 megabases.
Single-chromosome transcriptional profiling reveals chromosomal gene expression regulation from Marshall Levesque
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