�ݺ�ߣshows by User: PavanChittibabu

�ݺ�ߣshows by User: PavanChittibabu / http://www.slideshare.net/images/logo.gif �ݺ�ߣshows by User: PavanChittibabu / Tue, 25 Feb 2020 04:52:22 GMT �ݺ�ߣShare feed for �ݺ�ߣshows by User: PavanChittibabu Screening of Dyslipidemic drugs /slideshow/screening-of-dyslipidemic-drugs/229080300 dyslipidemia-200225045222
Dyslipidemia is a medical condition that refers to an abnormal level of blood lipids. The most common type of dyslipidemia is hyperlipidemia or high lipid levels. less common form of dyslipidemia: hypolipidemia, abnormally low lipid levels. Dyslipidemias can affect any lipid parameters including LDL cholesterol levels, HDL cholesterol levels, triglycerides, or a combination of these lipids. Two categories: Primary dyslipidemia Secondary dyslipidemia ]]>
Dyslipidemia is a medical condition that refers to an abnormal level of blood lipids. The most common type of dyslipidemia is hyperlipidemia or high lipid levels. less common form of dyslipidemia: hypolipidemia, abnormally low lipid levels. Dyslipidemias can affect any lipid parameters including LDL cholesterol levels, HDL cholesterol levels, triglycerides, or a combination of these lipids. Two categories: Primary dyslipidemia Secondary dyslipidemia ]]> Tue, 25 Feb 2020 04:52:22 GMT /slideshow/screening-of-dyslipidemic-drugs/229080300 PavanChittibabu@slideshare.net(PavanChittibabu) Screening of Dyslipidemic drugs PavanChittibabu Dyslipidemia is a medical condition that refers to an abnormal level of blood lipids. The most common type of dyslipidemia is hyperlipidemia or high lipid levels. less common form of dyslipidemia: hypolipidemia, abnormally low lipid levels. Dyslipidemias can affect any lipid parameters including LDL cholesterol levels, HDL cholesterol levels, triglycerides, or a combination of these lipids. Two categories: Primary dyslipidemia Secondary dyslipidemia <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/dyslipidemia-200225045222-thumbnail.jpg?width=120&height=120&fit=bounds" /> Dyslipidemia is a medical condition that refers to an abnormal level of blood lipids. The most common type of dyslipidemia is hyperlipidemia or high lipid levels. less common form of dyslipidemia: hypolipidemia, abnormally low lipid levels. Dyslipidemias can affect any lipid parameters including LDL cholesterol levels, HDL cholesterol levels, triglycerides, or a combination of these lipids. Two categories: Primary dyslipidemia Secondary dyslipidemia

Screening of Dyslipidemic drugs from Pavana K A

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0 Potentiometry /slideshow/potentiometry-229079562/229079562 potentiometry-200225044430
Potentiometry is an electrochemical method of Analysis deals with the measurement of electric potential or emf of an electrolyte solution under the condition of constant current. Potentiometry is the measurement of electrical potential of an electrolyte solution to determine its concentration. The principle is based on the fact that the potential of the given sample is directly proportional to the concentration of its electro active ions or its activity (pH) When the pair of electrodes is placed in the sample solution it shows the potential difference by the addition of the titrant or by the change in the concentration of the ions. The theory of potentiometry is based on the nernst equation.It gives the basic relationship between the potential generated by an electrochemical cell and the concentration of the ions. The potential E ( Half cell potential) of any electrode is given by nernst equation]]>
Potentiometry is an electrochemical method of Analysis deals with the measurement of electric potential or emf of an electrolyte solution under the condition of constant current. Potentiometry is the measurement of electrical potential of an electrolyte solution to determine its concentration. The principle is based on the fact that the potential of the given sample is directly proportional to the concentration of its electro active ions or its activity (pH) When the pair of electrodes is placed in the sample solution it shows the potential difference by the addition of the titrant or by the change in the concentration of the ions. The theory of potentiometry is based on the nernst equation.It gives the basic relationship between the potential generated by an electrochemical cell and the concentration of the ions. The potential E ( Half cell potential) of any electrode is given by nernst equation]]> Tue, 25 Feb 2020 04:44:30 GMT /slideshow/potentiometry-229079562/229079562 PavanChittibabu@slideshare.net(PavanChittibabu) Potentiometry PavanChittibabu Potentiometry is an electrochemical method of Analysis deals with the measurement of electric potential or emf of an electrolyte solution under the condition of constant current. Potentiometry is the measurement of electrical potential of an electrolyte solution to determine its concentration. The principle is based on the fact that the potential of the given sample is directly proportional to the concentration of its electro active ions or its activity (pH) When the pair of electrodes is placed in the sample solution it shows the potential difference by the addition of the titrant or by the change in the concentration of the ions. The theory of potentiometry is based on the nernst equation.It gives the basic relationship between the potential generated by an electrochemical cell and the concentration of the ions. The potential E ( Half cell potential) of any electrode is given by nernst equation <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/potentiometry-200225044430-thumbnail.jpg?width=120&height=120&fit=bounds" /> Potentiometry is an electrochemical method of Analysis deals with the measurement of electric potential or emf of an electrolyte solution under the condition of constant current. Potentiometry is the measurement of electrical potential of an electrolyte solution to determine its concentration. The principle is based on the fact that the potential of the given sample is directly proportional to the concentration of its electro active ions or its activity (pH) When the pair of electrodes is placed in the sample solution it shows the potential difference by the addition of the titrant or by the change in the concentration of the ions. The theory of potentiometry is based on the nernst equation.It gives the basic relationship between the potential generated by an electrochemical cell and the concentration of the ions. The potential E ( Half cell potential) of any electrode is given by nernst equation

Potentiometry from Pavana K A

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0 Safety Pharmacology /slideshow/safety-pharmacology-229079051/229079051 safetyharmacology-200225043858
Safety pharmacology is a branch of pharmacology with its aim to predict the potential clinical risk profile of new chemical entities (NCEs). It has the ability to predict the potential off-target drug effects on major organ systems which are associated with exposure in the therapeutic range and above. As an essential part of the spectrum of drug discovery and development, safety pharmacology studies are generally conducted to determine the relative drug effect on main organs, including respiratory system, central nervous system, and cardiovascular system.Safety pharmacology is an essential part of the drug development process that aims to identify and predict adverse effects prior to clinical trials. SP studies are described in the international conference on harmonization (ICH) S7A and S7B Guidelines. ]]>
Safety pharmacology is a branch of pharmacology with its aim to predict the potential clinical risk profile of new chemical entities (NCEs). It has the ability to predict the potential off-target drug effects on major organ systems which are associated with exposure in the therapeutic range and above. As an essential part of the spectrum of drug discovery and development, safety pharmacology studies are generally conducted to determine the relative drug effect on main organs, including respiratory system, central nervous system, and cardiovascular system.Safety pharmacology is an essential part of the drug development process that aims to identify and predict adverse effects prior to clinical trials. SP studies are described in the international conference on harmonization (ICH) S7A and S7B Guidelines. ]]> Tue, 25 Feb 2020 04:38:58 GMT /slideshow/safety-pharmacology-229079051/229079051 PavanChittibabu@slideshare.net(PavanChittibabu) Safety Pharmacology PavanChittibabu Safety pharmacology is a branch of pharmacology with its aim to predict the potential clinical risk profile of new chemical entities (NCEs). It has the ability to predict the potential off-target drug effects on major organ systems which are associated with exposure in the therapeutic range and above. As an essential part of the spectrum of drug discovery and development, safety pharmacology studies are generally conducted to determine the relative drug effect on main organs, including respiratory system, central nervous system, and cardiovascular system.Safety pharmacology is an essential part of the drug development process that aims to identify and predict adverse effects prior to clinical trials. SP studies are described in the international conference on harmonization (ICH) S7A and S7B Guidelines. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/safetyharmacology-200225043858-thumbnail.jpg?width=120&height=120&fit=bounds" /> Safety pharmacology is a branch of pharmacology with its aim to predict the potential clinical risk profile of new chemical entities (NCEs). It has the ability to predict the potential off-target drug effects on major organ systems which are associated with exposure in the therapeutic range and above. As an essential part of the spectrum of drug discovery and development, safety pharmacology studies are generally conducted to determine the relative drug effect on main organs, including respiratory system, central nervous system, and cardiovascular system.Safety pharmacology is an essential part of the drug development process that aims to identify and predict adverse effects prior to clinical trials. SP studies are described in the international conference on harmonization (ICH) S7A and S7B Guidelines.

Safety Pharmacology from Pavana K A

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0 Role of genomics and proteomics /slideshow/role-of-genomics-and-proteomics/229078825 roleofgenomicsandproteomics-200225043657
A genome is an organism’s complete set of DNA or complete genetic makeup, The entire DNA complement. It describes the identity and the sequence of genes of an organism. Genomics is the study of entire genomes(structure, function, evolution, mapping, and editing of genomes) Executing the sequencing and analysis of entire human genome enables more rapid and effective identification of disease associated genes and provide drug companies with pre validated targets. Proteomics is the systematic high-throughput separation and characterization of proteins within biological systems./ large scale study of protein and their functions. Proteomics measures protein expression directly, not via gene expression, thus achieving better accuracy. Current work uses 2-dimensional polyacrylamide gel electrophoresis(2D- PAGE) and mass spectrometry. New separation and characterization technologies, such as protein microarray and high throughput chromatography are being developed. ]]>
A genome is an organism’s complete set of DNA or complete genetic makeup, The entire DNA complement. It describes the identity and the sequence of genes of an organism. Genomics is the study of entire genomes(structure, function, evolution, mapping, and editing of genomes) Executing the sequencing and analysis of entire human genome enables more rapid and effective identification of disease associated genes and provide drug companies with pre validated targets. Proteomics is the systematic high-throughput separation and characterization of proteins within biological systems./ large scale study of protein and their functions. Proteomics measures protein expression directly, not via gene expression, thus achieving better accuracy. Current work uses 2-dimensional polyacrylamide gel electrophoresis(2D- PAGE) and mass spectrometry. New separation and characterization technologies, such as protein microarray and high throughput chromatography are being developed. ]]> Tue, 25 Feb 2020 04:36:57 GMT /slideshow/role-of-genomics-and-proteomics/229078825 PavanChittibabu@slideshare.net(PavanChittibabu) Role of genomics and proteomics PavanChittibabu A genome is an organism’s complete set of DNA or complete genetic makeup, The entire DNA complement. It describes the identity and the sequence of genes of an organism. Genomics is the study of entire genomes(structure, function, evolution, mapping, and editing of genomes) Executing the sequencing and analysis of entire human genome enables more rapid and effective identification of disease associated genes and provide drug companies with pre validated targets. Proteomics is the systematic high-throughput separation and characterization of proteins within biological systems./ large scale study of protein and their functions. Proteomics measures protein expression directly, not via gene expression, thus achieving better accuracy. Current work uses 2-dimensional polyacrylamide gel electrophoresis(2D- PAGE) and mass spectrometry. New separation and characterization technologies, such as protein microarray and high throughput chromatography are being developed. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/roleofgenomicsandproteomics-200225043657-thumbnail.jpg?width=120&height=120&fit=bounds" /> A genome is an organism’s complete set of DNA or complete genetic makeup, The entire DNA complement. It describes the identity and the sequence of genes of an organism. Genomics is the study of entire genomes(structure, function, evolution, mapping, and editing of genomes) Executing the sequencing and analysis of entire human genome enables more rapid and effective identification of disease associated genes and provide drug companies with pre validated targets. Proteomics is the systematic high-throughput separation and characterization of proteins within biological systems./ large scale study of protein and their functions. Proteomics measures protein expression directly, not via gene expression, thus achieving better accuracy. Current work uses 2-dimensional polyacrylamide gel electrophoresis(2D- PAGE) and mass spectrometry. New separation and characterization technologies, such as protein microarray and high throughput chromatography are being developed.

Role of genomics and proteomics from Pavana K A

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0 Prokinetics 1 /slideshow/prokinetics-1/229078292 prokinetics1-200225043224
Prokinetics are the type of drugs which enhances gastrointestinal motility/transit by increasing the frequency or strength of contractions. They speed up gastric emptying by enhancing coordinated propulsive motility. Treat Gastrointestinal symptoms : Abdominal discomfort, Bloating, constipation, Heart burn, nausea and vomiting. And few gastrointestinal disorders : irritable bowel Syndrome, gastritis, gastroparesis and functional dyspepsia. Increases gastric emptying Relief of gastric stasis Decreases reflux esophagitis/heart burn Decreases regurgitation of gastric contents& emesis ]]>
Prokinetics are the type of drugs which enhances gastrointestinal motility/transit by increasing the frequency or strength of contractions. They speed up gastric emptying by enhancing coordinated propulsive motility. Treat Gastrointestinal symptoms : Abdominal discomfort, Bloating, constipation, Heart burn, nausea and vomiting. And few gastrointestinal disorders : irritable bowel Syndrome, gastritis, gastroparesis and functional dyspepsia. Increases gastric emptying Relief of gastric stasis Decreases reflux esophagitis/heart burn Decreases regurgitation of gastric contents& emesis ]]> Tue, 25 Feb 2020 04:32:24 GMT /slideshow/prokinetics-1/229078292 PavanChittibabu@slideshare.net(PavanChittibabu) Prokinetics 1 PavanChittibabu Prokinetics are the type of drugs which enhances gastrointestinal motility/transit by increasing the frequency or strength of contractions. They speed up gastric emptying by enhancing coordinated propulsive motility. Treat Gastrointestinal symptoms : Abdominal discomfort, Bloating, constipation, Heart burn, nausea and vomiting. And few gastrointestinal disorders : irritable bowel Syndrome, gastritis, gastroparesis and functional dyspepsia. Increases gastric emptying Relief of gastric stasis Decreases reflux esophagitis/heart burn Decreases regurgitation of gastric contents�& emesis � <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/prokinetics1-200225043224-thumbnail.jpg?width=120&height=120&fit=bounds" /> Prokinetics are the type of drugs which enhances gastrointestinal motility/transit by increasing the frequency or strength of contractions. They speed up gastric emptying by enhancing coordinated propulsive motility. Treat Gastrointestinal symptoms : Abdominal discomfort, Bloating, constipation, Heart burn, nausea and vomiting. And few gastrointestinal disorders : irritable bowel Syndrome, gastritis, gastroparesis and functional dyspepsia. Increases gastric emptying Relief of gastric stasis Decreases reflux esophagitis/heart burn Decreases regurgitation of gastric contents�& emesis �

Prokinetics 1 from Pavana K A

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0 Gene therapy /slideshow/gene-therapy-229077624/229077624 genetherapy-200225042634
Gene therapy is the process of inserting genes into cells to prevent, treat or cure wide range of diseases. Gene therapy primarily involves genetic manipulations in animals or humans to correct a disease. Gene augmentation therapy: a DNA is inserted into the Genome to replace the missing gene product.Gene inhibition therapy: the antisense gene inhibits the expression of the dominant gene. ]]>
Gene therapy is the process of inserting genes into cells to prevent, treat or cure wide range of diseases. Gene therapy primarily involves genetic manipulations in animals or humans to correct a disease. Gene augmentation therapy: a DNA is inserted into the Genome to replace the missing gene product.Gene inhibition therapy: the antisense gene inhibits the expression of the dominant gene. ]]> Tue, 25 Feb 2020 04:26:34 GMT /slideshow/gene-therapy-229077624/229077624 PavanChittibabu@slideshare.net(PavanChittibabu) Gene therapy PavanChittibabu Gene therapy is the process of inserting genes into cells to prevent, treat or cure wide range of diseases. Gene therapy primarily involves genetic manipulations in animals or humans to correct a disease. Gene augmentation therapy: a DNA is inserted into the Genome to replace the missing gene product.Gene inhibition therapy: the antisense gene inhibits the expression of the dominant gene. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/genetherapy-200225042634-thumbnail.jpg?width=120&height=120&fit=bounds" /> Gene therapy is the process of inserting genes into cells to prevent, treat or cure wide range of diseases. Gene therapy primarily involves genetic manipulations in animals or humans to correct a disease. Gene augmentation therapy: a DNA is inserted into the Genome to replace the missing gene product.Gene inhibition therapy: the antisense gene inhibits the expression of the dominant gene.

Gene therapy from Pavana K A

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0 Cell signaling /slideshow/cell-signaling-229076073/229076073 cellsignaling-200225041302
Cell signaling / Signal Transduction / Transmembrane signaling. It is the process by which cells communicate with their environment and respond to external stimuli. When a signaling molecule(ligand) binds to its receptor, it alters the shape or activity of the receptor, triggering a change inside of the cell such as alteration in the activity of a gene / cell division. Thus the original Intercellular Signal is converted into an Intracellular Signal that triggers as a response. ]]>
Cell signaling / Signal Transduction / Transmembrane signaling. It is the process by which cells communicate with their environment and respond to external stimuli. When a signaling molecule(ligand) binds to its receptor, it alters the shape or activity of the receptor, triggering a change inside of the cell such as alteration in the activity of a gene / cell division. Thus the original Intercellular Signal is converted into an Intracellular Signal that triggers as a response. ]]> Tue, 25 Feb 2020 04:13:02 GMT /slideshow/cell-signaling-229076073/229076073 PavanChittibabu@slideshare.net(PavanChittibabu) Cell signaling PavanChittibabu Cell signaling / Signal Transduction / Transmembrane signaling. It is the process by which cells communicate with their environment and respond to external stimuli. When a signaling molecule(ligand) binds to its receptor, it alters the shape or activity of the receptor, triggering a change inside of the cell such as alteration in the activity of a gene / cell division. Thus the original Intercellular Signal is converted into an Intracellular Signal that triggers as a response. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/cellsignaling-200225041302-thumbnail.jpg?width=120&height=120&fit=bounds" /> Cell signaling / Signal Transduction / Transmembrane signaling. It is the process by which cells communicate with their environment and respond to external stimuli. When a signaling molecule(ligand) binds to its receptor, it alters the shape or activity of the receptor, triggering a change inside of the cell such as alteration in the activity of a gene / cell division. Thus the original Intercellular Signal is converted into an Intracellular Signal that triggers as a response.

Cell signaling from Pavana K A

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0 Endocrine pharmacology /slideshow/endocrine-pharmacology-165575190/165575190 endocrinepharmacology-190822150017
Introduction to the endocrine system Growth hormone: Mechanism of Action, secretion, regulation. Prolactin Sex hormones Oral contraceptives Corticosteroids ]]>
Introduction to the endocrine system Growth hormone: Mechanism of Action, secretion, regulation. Prolactin Sex hormones Oral contraceptives Corticosteroids ]]> Thu, 22 Aug 2019 15:00:16 GMT /slideshow/endocrine-pharmacology-165575190/165575190 PavanChittibabu@slideshare.net(PavanChittibabu) Endocrine pharmacology PavanChittibabu Introduction to the endocrine system Growth hormone: Mechanism of Action, secretion, regulation. Prolactin Sex hormones Oral contraceptives Corticosteroids <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/endocrinepharmacology-190822150017-thumbnail.jpg?width=120&height=120&fit=bounds" /> Introduction to the endocrine system Growth hormone: Mechanism of Action, secretion, regulation. Prolactin Sex hormones Oral contraceptives Corticosteroids

Endocrine pharmacology from Pavana K A

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0 Anti ulcer screening /slideshow/anti-ulcer-screening/165570648 antiulcerscreening-190822143415
A Brief Introduction to Ulcers: What are ulcers, its causes, and symptoms. Classification of Antiulcer drugs and their adverse effects. List of all the screening models available for Antiulcer drugs. Few of the models are explained with their Principle, procedures, Evaluation, and assessment.]]>
A Brief Introduction to Ulcers: What are ulcers, its causes, and symptoms. Classification of Antiulcer drugs and their adverse effects. List of all the screening models available for Antiulcer drugs. Few of the models are explained with their Principle, procedures, Evaluation, and assessment.]]> Thu, 22 Aug 2019 14:34:15 GMT /slideshow/anti-ulcer-screening/165570648 PavanChittibabu@slideshare.net(PavanChittibabu) Anti ulcer screening PavanChittibabu A Brief Introduction to Ulcers: What are ulcers, its causes, and symptoms. Classification of Antiulcer drugs and their adverse effects. List of all the screening models available for Antiulcer drugs. Few of the models are explained with their Principle, procedures, Evaluation, and assessment. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/antiulcerscreening-190822143415-thumbnail.jpg?width=120&height=120&fit=bounds" /> A Brief Introduction to Ulcers: What are ulcers, its causes, and symptoms. Classification of Antiulcer drugs and their adverse effects. List of all the screening models available for Antiulcer drugs. Few of the models are explained with their Principle, procedures, Evaluation, and assessment.

Anti ulcer screening from Pavana K A

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0 https://public.slidesharecdn.com/v2/images/profile-picture.png https://cdn.slidesharecdn.com/ss_thumbnails/dyslipidemia-200225045222-thumbnail.jpg?width=320&height=320&fit=bounds slideshow/screening-of-dyslipidemic-drugs/229080300 Screening of Dyslipide... https://cdn.slidesharecdn.com/ss_thumbnails/potentiometry-200225044430-thumbnail.jpg?width=320&height=320&fit=bounds slideshow/potentiometry-229079562/229079562 Potentiometry https://cdn.slidesharecdn.com/ss_thumbnails/safetyharmacology-200225043858-thumbnail.jpg?width=320&height=320&fit=bounds slideshow/safety-pharmacology-229079051/229079051 Safety Pharmacology