ºÝºÝߣshows by User: TosohBioscienceGmbH / http://www.slideshare.net/images/logo.gif ºÝºÝߣshows by User: TosohBioscienceGmbH / Mon, 02 Jun 2014 09:15:01 GMT ºÝºÝߣShare feed for ºÝºÝߣshows by User: TosohBioscienceGmbH Robustness toyopearl mx trp650 m /slideshow/robustness-toyopearl-mx-trp650-m/35387358 robustnesstoyopearlmxtrp650m-140602091501-phpapp02
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Mon, 02 Jun 2014 09:15:01 GMT /slideshow/robustness-toyopearl-mx-trp650-m/35387358 TosohBioscienceGmbH@slideshare.net(TosohBioscienceGmbH) Robustness toyopearl mx trp650 m TosohBioscienceGmbH <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/robustnesstoyopearlmxtrp650m-140602091501-phpapp02-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br>
Robustness toyopearl mx trp650 m from Tosoh Bioscience GmbH
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TSKgel SW columns for mAb separation /slideshow/product-information-sw-columns-for-m-ab-separation/29108166 productinformationswcolumnsformabseparation-131211074335-phpapp01
Features of new SEC columns: •TSKgel SuperSW mAb HR exhibits superior resolving power for IgG monomer and dimer compared to other SEC columns. •TSKgel SuperSW mAb HTP exhibits equal separation between IgG monomer and dimer in half the analysis time compared to the current gold standard for mAb SEC - TSKgel G3000SWXL (5 μm particle, 7.8 mm ID x 30 cm). •TSKgel UltraSW Aggregate possesses a larger MW exclusion limit and shows superior resolving power for multimers and aggregates of large proteins, including thyroglobulin and IgG. The performance of these columns was demonstrated by the separation of IgG monomer, dimer, aggregates and fragment. The columns show good lot-to-lot reproducibility and column durability.]]>

Features of new SEC columns: •TSKgel SuperSW mAb HR exhibits superior resolving power for IgG monomer and dimer compared to other SEC columns. •TSKgel SuperSW mAb HTP exhibits equal separation between IgG monomer and dimer in half the analysis time compared to the current gold standard for mAb SEC - TSKgel G3000SWXL (5 μm particle, 7.8 mm ID x 30 cm). •TSKgel UltraSW Aggregate possesses a larger MW exclusion limit and shows superior resolving power for multimers and aggregates of large proteins, including thyroglobulin and IgG. The performance of these columns was demonstrated by the separation of IgG monomer, dimer, aggregates and fragment. The columns show good lot-to-lot reproducibility and column durability.]]>
Wed, 11 Dec 2013 07:43:35 GMT /slideshow/product-information-sw-columns-for-m-ab-separation/29108166 TosohBioscienceGmbH@slideshare.net(TosohBioscienceGmbH) TSKgel SW columns for mAb separation TosohBioscienceGmbH Features of new SEC columns: •TSKgel SuperSW mAb HR exhibits superior resolving power for IgG monomer and dimer compared to other SEC columns. •TSKgel SuperSW mAb HTP exhibits equal separation between IgG monomer and dimer in half the analysis time compared to the current gold standard for mAb SEC - TSKgel G3000SWXL (5 μm particle, 7.8 mm ID x 30 cm). •TSKgel UltraSW Aggregate possesses a larger MW exclusion limit and shows superior resolving power for multimers and aggregates of large proteins, including thyroglobulin and IgG. The performance of these columns was demonstrated by the separation of IgG monomer, dimer, aggregates and fragment. The columns show good lot-to-lot reproducibility and column durability. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/productinformationswcolumnsformabseparation-131211074335-phpapp01-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> Features of new SEC columns: •TSKgel SuperSW mAb HR exhibits superior resolving power for IgG monomer and dimer compared to other SEC columns. •TSKgel SuperSW mAb HTP exhibits equal separation between IgG monomer and dimer in half the analysis time compared to the current gold standard for mAb SEC - TSKgel G3000SWXL (5 μm particle, 7.8 mm ID x 30 cm). •TSKgel UltraSW Aggregate possesses a larger MW exclusion limit and shows superior resolving power for multimers and aggregates of large proteins, including thyroglobulin and IgG. The performance of these columns was demonstrated by the separation of IgG monomer, dimer, aggregates and fragment. The columns show good lot-to-lot reproducibility and column durability.
TSKgel SW columns for mAb separation from Tosoh Bioscience GmbH
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New Ultra-High Capacity TOYOPEARL® Protein A Resin /TosohBioscienceGmbH/toyopearl-af-r-protein-a-hc650fproduct-information toyopearlaf-rproteinahc-650fproductinformation-131211073041-phpapp02
High capacity chromatography resin for the capture and purification of monoclonal antibodies Tosoh Bioscience, a provider of chromatographic solutions for the isolation and analysis of biomolecules, introduced a new Protein A chromatography resin designed for the purification of monoclonal antibodies (mAbs). It is well-suited for high capacity capturing of immunoglobulin out of high titer feedstock. TOYOPEARL AF-rProtein A HC-650F achieves 30% to 50% greater antibody adsorption than similar products. It exhibits dynamic binding capacities of greater than 70 g/L at residence times of 5 minutes and greater than 50 g/L at residence times of 2 minutes with feedstock titers from 1 g/L to more than 10 g/L. The recombinant ligand that is linked to the well proven methacrylic polymer backbone of TOYOPEARL media has been engineered to maintain capacity even after repeated exposure to alkaline solution. Its multipoint attachment to the TOYOPEARL matrix further enhances chemical and thermal stability. In practice this pays off for a low level of Protein A leaching and also for a high resistance to alkaline solutions applied in cleaning-in-place (CIP) procedures. Due to its rigid polymer matrix TOYOPEARL AF-rProtein A HC-650F also provides excellent pressure flow characteristics. Protein A resins constitute a substantial cost in state-of-the-art mAb purification processes. Factors such as operating cycles, capacity, and mAb titer can have an impact on total costs associated with mAb purification. The high capacity of the new TOYOPEARL AF-rProtein A HC-650F resin and its high alkaline resistance increase product throughput, reduce operating costs and increase manufacturing productivity. ]]>

High capacity chromatography resin for the capture and purification of monoclonal antibodies Tosoh Bioscience, a provider of chromatographic solutions for the isolation and analysis of biomolecules, introduced a new Protein A chromatography resin designed for the purification of monoclonal antibodies (mAbs). It is well-suited for high capacity capturing of immunoglobulin out of high titer feedstock. TOYOPEARL AF-rProtein A HC-650F achieves 30% to 50% greater antibody adsorption than similar products. It exhibits dynamic binding capacities of greater than 70 g/L at residence times of 5 minutes and greater than 50 g/L at residence times of 2 minutes with feedstock titers from 1 g/L to more than 10 g/L. The recombinant ligand that is linked to the well proven methacrylic polymer backbone of TOYOPEARL media has been engineered to maintain capacity even after repeated exposure to alkaline solution. Its multipoint attachment to the TOYOPEARL matrix further enhances chemical and thermal stability. In practice this pays off for a low level of Protein A leaching and also for a high resistance to alkaline solutions applied in cleaning-in-place (CIP) procedures. Due to its rigid polymer matrix TOYOPEARL AF-rProtein A HC-650F also provides excellent pressure flow characteristics. Protein A resins constitute a substantial cost in state-of-the-art mAb purification processes. Factors such as operating cycles, capacity, and mAb titer can have an impact on total costs associated with mAb purification. The high capacity of the new TOYOPEARL AF-rProtein A HC-650F resin and its high alkaline resistance increase product throughput, reduce operating costs and increase manufacturing productivity. ]]>
Wed, 11 Dec 2013 07:30:41 GMT /TosohBioscienceGmbH/toyopearl-af-r-protein-a-hc650fproduct-information TosohBioscienceGmbH@slideshare.net(TosohBioscienceGmbH) New Ultra-High Capacity TOYOPEARL® Protein A Resin TosohBioscienceGmbH High capacity chromatography resin for the capture and purification of monoclonal antibodies Tosoh Bioscience, a provider of chromatographic solutions for the isolation and analysis of biomolecules, introduced a new Protein A chromatography resin designed for the purification of monoclonal antibodies (mAbs). It is well-suited for high capacity capturing of immunoglobulin out of high titer feedstock. TOYOPEARL AF-rProtein A HC-650F achieves 30% to 50% greater antibody adsorption than similar products. It exhibits dynamic binding capacities of greater than 70 g/L at residence times of 5 minutes and greater than 50 g/L at residence times of 2 minutes with feedstock titers from 1 g/L to more than 10 g/L. The recombinant ligand that is linked to the well proven methacrylic polymer backbone of TOYOPEARL media has been engineered to maintain capacity even after repeated exposure to alkaline solution. Its multipoint attachment to the TOYOPEARL matrix further enhances chemical and thermal stability. In practice this pays off for a low level of Protein A leaching and also for a high resistance to alkaline solutions applied in cleaning-in-place (CIP) procedures. Due to its rigid polymer matrix TOYOPEARL AF-rProtein A HC-650F also provides excellent pressure flow characteristics. Protein A resins constitute a substantial cost in state-of-the-art mAb purification processes. Factors such as operating cycles, capacity, and mAb titer can have an impact on total costs associated with mAb purification. The high capacity of the new TOYOPEARL AF-rProtein A HC-650F resin and its high alkaline resistance increase product throughput, reduce operating costs and increase manufacturing productivity. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/toyopearlaf-rproteinahc-650fproductinformation-131211073041-phpapp02-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> High capacity chromatography resin for the capture and purification of monoclonal antibodies Tosoh Bioscience, a provider of chromatographic solutions for the isolation and analysis of biomolecules, introduced a new Protein A chromatography resin designed for the purification of monoclonal antibodies (mAbs). It is well-suited for high capacity capturing of immunoglobulin out of high titer feedstock. TOYOPEARL AF-rProtein A HC-650F achieves 30% to 50% greater antibody adsorption than similar products. It exhibits dynamic binding capacities of greater than 70 g/L at residence times of 5 minutes and greater than 50 g/L at residence times of 2 minutes with feedstock titers from 1 g/L to more than 10 g/L. The recombinant ligand that is linked to the well proven methacrylic polymer backbone of TOYOPEARL media has been engineered to maintain capacity even after repeated exposure to alkaline solution. Its multipoint attachment to the TOYOPEARL matrix further enhances chemical and thermal stability. In practice this pays off for a low level of Protein A leaching and also for a high resistance to alkaline solutions applied in cleaning-in-place (CIP) procedures. Due to its rigid polymer matrix TOYOPEARL AF-rProtein A HC-650F also provides excellent pressure flow characteristics. Protein A resins constitute a substantial cost in state-of-the-art mAb purification processes. Factors such as operating cycles, capacity, and mAb titer can have an impact on total costs associated with mAb purification. The high capacity of the new TOYOPEARL AF-rProtein A HC-650F resin and its high alkaline resistance increase product throughput, reduce operating costs and increase manufacturing productivity.
New Ultra-High Capacity TOYOPEARL速 Protein A Resin from Tosoh Bioscience GmbH
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TOYOPEARL GigaCap DEAE product information /TosohBioscienceGmbH/toyopearl-gigacap-deae-product-information toyopearlgigacapdeaeproductinformation-131024071349-phpapp02
TOYOPEARL GigaCap DEAE is a weak anion exchanger that offers a binding capacity of over 150 g/L for bovine serum albumin, which exceeds the DBC of all other commercial available DEAE anion exchange media. Besides other applications this is of special interest for the purification of plasma proteins.]]>

TOYOPEARL GigaCap DEAE is a weak anion exchanger that offers a binding capacity of over 150 g/L for bovine serum albumin, which exceeds the DBC of all other commercial available DEAE anion exchange media. Besides other applications this is of special interest for the purification of plasma proteins.]]>
Thu, 24 Oct 2013 07:13:49 GMT /TosohBioscienceGmbH/toyopearl-gigacap-deae-product-information TosohBioscienceGmbH@slideshare.net(TosohBioscienceGmbH) TOYOPEARL GigaCap DEAE product information TosohBioscienceGmbH TOYOPEARL GigaCap DEAE is a weak anion exchanger that offers a binding capacity of over 150 g/L for bovine serum albumin, which exceeds the DBC of all other commercial available DEAE anion exchange media. Besides other applications this is of special interest for the purification of plasma proteins. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/toyopearlgigacapdeaeproductinformation-131024071349-phpapp02-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> TOYOPEARL GigaCap DEAE is a weak anion exchanger that offers a binding capacity of over 150 g/L for bovine serum albumin, which exceeds the DBC of all other commercial available DEAE anion exchange media. Besides other applications this is of special interest for the purification of plasma proteins.
TOYOPEARL GigaCap DEAE product information from Tosoh Bioscience GmbH
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https://cdn.slidesharecdn.com/profile-photo-TosohBioscienceGmbH-48x48.jpg?cb=1523671691 Tosoh’s product portfolio encompasses GPC instruments and a comprehensive line of Toyopearl and TSKgel chromatography media and prepacked TSKgel HPLC columns. Tosoh Bioscience offers chromatography solutions for research, drug discovery, medicinal chemistry, environmental analysis, manufacturing and other industrial applications for all common modes of liquid chromatography, including IEC, HIC, RPC, HILIC, SEC and affinity. http://www.separations.eu.tosohbioscience.com/ https://cdn.slidesharecdn.com/ss_thumbnails/robustnesstoyopearlmxtrp650m-140602091501-phpapp02-thumbnail.jpg?width=320&height=320&fit=bounds slideshow/robustness-toyopearl-mx-trp650-m/35387358 Robustness toyopearl m... https://cdn.slidesharecdn.com/ss_thumbnails/productinformationswcolumnsformabseparation-131211074335-phpapp01-thumbnail.jpg?width=320&height=320&fit=bounds slideshow/product-information-sw-columns-for-m-ab-separation/29108166 TSKgel SW columns for ... https://cdn.slidesharecdn.com/ss_thumbnails/toyopearlaf-rproteinahc-650fproductinformation-131211073041-phpapp02-thumbnail.jpg?width=320&height=320&fit=bounds TosohBioscienceGmbH/toyopearl-af-r-protein-a-hc650fproduct-information New Ultra-High Capacit...