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Wed, 13 Mar 2019 00:43:06 GMT狠狠撸Share feed for 狠狠撸shows by User: goodbRepresenting and reasoning with biological knowledge
/slideshow/representing-and-reasoning-with-biological-knowledge/135979348
representingandreasoningwithbiologicalknowledge-us2ts-2019-190313004306 Introduces the Gene Ontology, GO Causal Activity Models, and shows how OWL reasoning is used in the project. ]]>
Introduces the Gene Ontology, GO Causal Activity Models, and shows how OWL reasoning is used in the project. ]]>
Wed, 13 Mar 2019 00:43:06 GMT/slideshow/representing-and-reasoning-with-biological-knowledge/135979348goodb@slideshare.net(goodb)Representing and reasoning with biological knowledgegoodbIntroduces the Gene Ontology, GO Causal Activity Models, and shows how OWL reasoning is used in the project. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/representingandreasoningwithbiologicalknowledge-us2ts-2019-190313004306-thumbnail.jpg?width=120&height=120&fit=bounds" /><br> Introduces the Gene Ontology, GO Causal Activity Models, and shows how OWL reasoning is used in the project.
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4324https://cdn.slidesharecdn.com/ss_thumbnails/representingandreasoningwithbiologicalknowledge-us2ts-2019-190313004306-thumbnail.jpg?width=120&height=120&fit=boundspresentationBlackhttp://activitystrea.ms/schema/1.0/posthttp://activitystrea.ms/schema/1.0/posted0Integrating Pathway Databases with Gene Ontology Causal Activity Models
/goodb/integrating-pathway-databases-with-gene-ontology-causal-activity-models
good-pathways2go-rockyaspen-2018-powerpoint-181208004827 The Gene Ontology (GO) Consortium (GOC) is developing a new knowledge representation approach called 鈥榗ausal activity models鈥� (GO-CAM). A GO-CAM describes how one or several gene products contribute to the execution of a biological process. In these models (implemented as OWL instance graphs anchored in Open Biological Ontology (OBO) classes and relations), gene products are linked to molecular activities via semantic relationships like 鈥榚nables鈥�, molecular activities are linked to each other via causal relationships such as 鈥榩ositively regulates鈥�, and sets of molecular activities are defined as 鈥榩arts鈥� of larger biological processes. This approach provides the GOC with a more complete and extensible structure for capturing knowledge of gene function. It also allows for the representation of knowledge typically seen in pathway databases.
Here, we present details and results of a rule-based transformation of pathways represented using the BioPAX exchange format into GO-CAMs. We have automatically converted all Reactome pathways into GO-CAMs and are currently working on the conversion of additional resources available through Pathway Commons. By converting pathways into GO-CAMs, we can leverage OWL description logic reasoning over OBO ontologies to infer new biological relationships and detect logical inconsistencies. Further, the conversion helps to increase standardization for the representation of biological entities and processes. The products of this work can be used to improve source databases, for example by inferring new GO annotations for pathways and reactions and can help with the formation of meta-knowledge bases that integrate content from multiple sources.]]>
The Gene Ontology (GO) Consortium (GOC) is developing a new knowledge representation approach called 鈥榗ausal activity models鈥� (GO-CAM). A GO-CAM describes how one or several gene products contribute to the execution of a biological process. In these models (implemented as OWL instance graphs anchored in Open Biological Ontology (OBO) classes and relations), gene products are linked to molecular activities via semantic relationships like 鈥榚nables鈥�, molecular activities are linked to each other via causal relationships such as 鈥榩ositively regulates鈥�, and sets of molecular activities are defined as 鈥榩arts鈥� of larger biological processes. This approach provides the GOC with a more complete and extensible structure for capturing knowledge of gene function. It also allows for the representation of knowledge typically seen in pathway databases.
Here, we present details and results of a rule-based transformation of pathways represented using the BioPAX exchange format into GO-CAMs. We have automatically converted all Reactome pathways into GO-CAMs and are currently working on the conversion of additional resources available through Pathway Commons. By converting pathways into GO-CAMs, we can leverage OWL description logic reasoning over OBO ontologies to infer new biological relationships and detect logical inconsistencies. Further, the conversion helps to increase standardization for the representation of biological entities and processes. The products of this work can be used to improve source databases, for example by inferring new GO annotations for pathways and reactions and can help with the formation of meta-knowledge bases that integrate content from multiple sources.]]>
Sat, 08 Dec 2018 00:48:27 GMT/goodb/integrating-pathway-databases-with-gene-ontology-causal-activity-modelsgoodb@slideshare.net(goodb)Integrating Pathway Databases with Gene Ontology Causal Activity ModelsgoodbThe Gene Ontology (GO) Consortium (GOC) is developing a new knowledge representation approach called 鈥榗ausal activity models鈥� (GO-CAM). A GO-CAM describes how one or several gene products contribute to the execution of a biological process. In these models (implemented as OWL instance graphs anchored in Open Biological Ontology (OBO) classes and relations), gene products are linked to molecular activities via semantic relationships like 鈥榚nables鈥�, molecular activities are linked to each other via causal relationships such as 鈥榩ositively regulates鈥�, and sets of molecular activities are defined as 鈥榩arts鈥� of larger biological processes. This approach provides the GOC with a more complete and extensible structure for capturing knowledge of gene function. It also allows for the representation of knowledge typically seen in pathway databases.
Here, we present details and results of a rule-based transformation of pathways represented using the BioPAX exchange format into GO-CAMs. We have automatically converted all Reactome pathways into GO-CAMs and are currently working on the conversion of additional resources available through Pathway Commons. By converting pathways into GO-CAMs, we can leverage OWL description logic reasoning over OBO ontologies to infer new biological relationships and detect logical inconsistencies. Further, the conversion helps to increase standardization for the representation of biological entities and processes. The products of this work can be used to improve source databases, for example by inferring new GO annotations for pathways and reactions and can help with the formation of meta-knowledge bases that integrate content from multiple sources.<img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/good-pathways2go-rockyaspen-2018-powerpoint-181208004827-thumbnail.jpg?width=120&height=120&fit=bounds" /><br> The Gene Ontology (GO) Consortium (GOC) is developing a new knowledge representation approach called 鈥榗ausal activity models鈥� (GO-CAM). A GO-CAM describes how one or several gene products contribute to the execution of a biological process. In these models (implemented as OWL instance graphs anchored in Open Biological Ontology (OBO) classes and relations), gene products are linked to molecular activities via semantic relationships like 鈥榚nables鈥�, molecular activities are linked to each other via causal relationships such as 鈥榩ositively regulates鈥�, and sets of molecular activities are defined as 鈥榩arts鈥� of larger biological processes. This approach provides the GOC with a more complete and extensible structure for capturing knowledge of gene function. It also allows for the representation of knowledge typically seen in pathway databases.
Here, we present details and results of a rule-based transformation of pathways represented using the BioPAX exchange format into GO-CAMs. We have automatically converted all Reactome pathways into GO-CAMs and are currently working on the conversion of additional resources available through Pathway Commons. By converting pathways into GO-CAMs, we can leverage OWL description logic reasoning over OBO ontologies to infer new biological relationships and detect logical inconsistencies. Further, the conversion helps to increase standardization for the representation of biological entities and processes. The products of this work can be used to improve source databases, for example by inferring new GO annotations for pathways and reactions and can help with the formation of meta-knowledge bases that integrate content from multiple sources.
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6095https://cdn.slidesharecdn.com/ss_thumbnails/good-pathways2go-rockyaspen-2018-powerpoint-181208004827-thumbnail.jpg?width=120&height=120&fit=boundspresentationBlackhttp://activitystrea.ms/schema/1.0/posthttp://activitystrea.ms/schema/1.0/posted0Pathways2GO: Converting BioPax pathways to GO-CAMs
/slideshow/pathways2go-converting-biopax-pathways-to-gocams/98000547
pathways2go-gocnyu2018-180522042203 Presentation at the Gene Ontology Consortium Annual Meeting. Describing the automatic conversion of biochemical pathways in the Reactome Knowledge Base into the Gene Ontology 'Causal Activity Model' representation. ]]>
Presentation at the Gene Ontology Consortium Annual Meeting. Describing the automatic conversion of biochemical pathways in the Reactome Knowledge Base into the Gene Ontology 'Causal Activity Model' representation. ]]>
Tue, 22 May 2018 04:22:02 GMT/slideshow/pathways2go-converting-biopax-pathways-to-gocams/98000547goodb@slideshare.net(goodb)Pathways2GO: Converting BioPax pathways to GO-CAMsgoodbPresentation at the Gene Ontology Consortium Annual Meeting. Describing the automatic conversion of biochemical pathways in the Reactome Knowledge Base into the Gene Ontology 'Causal Activity Model' representation. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/pathways2go-gocnyu2018-180522042203-thumbnail.jpg?width=120&height=120&fit=bounds" /><br> Presentation at the Gene Ontology Consortium Annual Meeting. Describing the automatic conversion of biochemical pathways in the Reactome Knowledge Base into the Gene Ontology 'Causal Activity Model' representation.
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3052https://cdn.slidesharecdn.com/ss_thumbnails/pathways2go-gocnyu2018-180522042203-thumbnail.jpg?width=120&height=120&fit=boundspresentationBlackhttp://activitystrea.ms/schema/1.0/posthttp://activitystrea.ms/schema/1.0/posted0Knowledge Beacons
/slideshow/knowledge-beacons/75514950
isvbcjaqsaegitg4hu04-signature-1c315c52f069974d47c22cba0d522b094d21eb9bd366cf13e7cb89bdbd1fe3ac-poli-170428225601 Riffing on the GA4GH Beacon concept as a path towards semantic web services for biomedical knowledge. ]]>
Riffing on the GA4GH Beacon concept as a path towards semantic web services for biomedical knowledge. ]]>
Fri, 28 Apr 2017 22:56:01 GMT/slideshow/knowledge-beacons/75514950goodb@slideshare.net(goodb)Knowledge BeaconsgoodbRiffing on the GA4GH Beacon concept as a path towards semantic web services for biomedical knowledge. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/isvbcjaqsaegitg4hu04-signature-1c315c52f069974d47c22cba0d522b094d21eb9bd366cf13e7cb89bdbd1fe3ac-poli-170428225601-thumbnail.jpg?width=120&height=120&fit=bounds" /><br> Riffing on the GA4GH Beacon concept as a path towards semantic web services for biomedical knowledge.
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6832https://cdn.slidesharecdn.com/ss_thumbnails/isvbcjaqsaegitg4hu04-signature-1c315c52f069974d47c22cba0d522b094d21eb9bd366cf13e7cb89bdbd1fe3ac-poli-170428225601-thumbnail.jpg?width=120&height=120&fit=boundspresentationBlackhttp://activitystrea.ms/schema/1.0/posthttp://activitystrea.ms/schema/1.0/posted0Building a Biomedical Knowledge Garden
/slideshow/building-a-biomedical-knowledge-garden/69777856
8cy9x6i2svctkokdozxb-signature-0013ace2833a9a83b26035006a6549480cf284ce33e4faa17ee6e18991236298-poli-161203001106 Describes the tribulations of building a large biomedical knowledge graph. Provides a comparison between the UMLS and Wikidata in terms of content and structure. Concludes with the idea of anchoring the knowledge graph in Wikidata items and properties. ]]>
Describes the tribulations of building a large biomedical knowledge graph. Provides a comparison between the UMLS and Wikidata in terms of content and structure. Concludes with the idea of anchoring the knowledge graph in Wikidata items and properties. ]]>
Sat, 03 Dec 2016 00:11:06 GMT/slideshow/building-a-biomedical-knowledge-garden/69777856goodb@slideshare.net(goodb)Building a Biomedical Knowledge Garden goodbDescribes the tribulations of building a large biomedical knowledge graph. Provides a comparison between the UMLS and Wikidata in terms of content and structure. Concludes with the idea of anchoring the knowledge graph in Wikidata items and properties. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/8cy9x6i2svctkokdozxb-signature-0013ace2833a9a83b26035006a6549480cf284ce33e4faa17ee6e18991236298-poli-161203001106-thumbnail.jpg?width=120&height=120&fit=bounds" /><br> Describes the tribulations of building a large biomedical knowledge graph. Provides a comparison between the UMLS and Wikidata in terms of content and structure. Concludes with the idea of anchoring the knowledge graph in Wikidata items and properties.
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61106https://cdn.slidesharecdn.com/ss_thumbnails/8cy9x6i2svctkokdozxb-signature-0013ace2833a9a83b26035006a6549480cf284ce33e4faa17ee6e18991236298-poli-161203001106-thumbnail.jpg?width=120&height=120&fit=boundspresentationBlackhttp://activitystrea.ms/schema/1.0/posthttp://activitystrea.ms/schema/1.0/posted0Science Game Lab
/slideshow/science-game-lab/69262152
9fwcfomwslmdjpbntuji-signature-a933cc3b912d9ffbb3ab4467ebe60cc891ac569a0531368727c06070be83451d-poli-161118170718 When the Heart BD2K grant was originally written. We proposed to build something called 鈥淏ig Data World鈥� to help advance citizen science, scientific crowdsourcing and science education 鈥� especially in bioinformatics. This past year, this idea has become Science Game Lab ( https://sciencegamelab.org ) . A collaboration between the Su laboratory at Scripps Research, Playmatics LLC, and recently the creators of WikiPathways.
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When the Heart BD2K grant was originally written. We proposed to build something called 鈥淏ig Data World鈥� to help advance citizen science, scientific crowdsourcing and science education 鈥� especially in bioinformatics. This past year, this idea has become Science Game Lab ( https://sciencegamelab.org ) . A collaboration between the Su laboratory at Scripps Research, Playmatics LLC, and recently the creators of WikiPathways.
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Fri, 18 Nov 2016 17:07:18 GMT/slideshow/science-game-lab/69262152goodb@slideshare.net(goodb)Science Game LabgoodbWhen the Heart BD2K grant was originally written. We proposed to build something called 鈥淏ig Data World鈥� to help advance citizen science, scientific crowdsourcing and science education 鈥� especially in bioinformatics. This past year, this idea has become Science Game Lab ( https://sciencegamelab.org ) . A collaboration between the Su laboratory at Scripps Research, Playmatics LLC, and recently the creators of WikiPathways.
<img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/9fwcfomwslmdjpbntuji-signature-a933cc3b912d9ffbb3ab4467ebe60cc891ac569a0531368727c06070be83451d-poli-161118170718-thumbnail.jpg?width=120&height=120&fit=bounds" /><br> When the Heart BD2K grant was originally written. We proposed to build something called 鈥淏ig Data World鈥� to help advance citizen science, scientific crowdsourcing and science education 鈥� especially in bioinformatics. This past year, this idea has become Science Game Lab ( https://sciencegamelab.org ) . A collaboration between the Su laboratory at Scripps Research, Playmatics LLC, and recently the creators of WikiPathways.
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8015https://cdn.slidesharecdn.com/ss_thumbnails/9fwcfomwslmdjpbntuji-signature-a933cc3b912d9ffbb3ab4467ebe60cc891ac569a0531368727c06070be83451d-poli-161118170718-thumbnail.jpg?width=120&height=120&fit=boundspresentationBlackhttp://activitystrea.ms/schema/1.0/posthttp://activitystrea.ms/schema/1.0/posted0Wikidata and the Semantic Web of Food
/slideshow/wikidata-and-the-semantic-web-of-food/68512410
w5d9durltfa6m3zmfdqe-signature-280947269b16f63a5ea3324e26b991309cdd8354303d8a62de82ccb706bad45f-poli-161109190121 A 10 minute introduction to Wikidata, the Gene Wiki project, and the Semantic Web. Presented at IC-Foods inaugural conference at UC Davis]]>
A 10 minute introduction to Wikidata, the Gene Wiki project, and the Semantic Web. Presented at IC-Foods inaugural conference at UC Davis]]>
Wed, 09 Nov 2016 19:01:20 GMT/slideshow/wikidata-and-the-semantic-web-of-food/68512410goodb@slideshare.net(goodb)Wikidata and the Semantic Web of FoodgoodbA 10 minute introduction to Wikidata, the Gene Wiki project, and the Semantic Web. Presented at IC-Foods inaugural conference at UC Davis<img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/w5d9durltfa6m3zmfdqe-signature-280947269b16f63a5ea3324e26b991309cdd8354303d8a62de82ccb706bad45f-poli-161109190121-thumbnail.jpg?width=120&height=120&fit=bounds" /><br> A 10 minute introduction to Wikidata, the Gene Wiki project, and the Semantic Web. Presented at IC-Foods inaugural conference at UC Davis
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56183https://cdn.slidesharecdn.com/ss_thumbnails/w5d9durltfa6m3zmfdqe-signature-280947269b16f63a5ea3324e26b991309cdd8354303d8a62de82ccb706bad45f-poli-161109190121-thumbnail.jpg?width=120&height=120&fit=boundspresentationBlackhttp://activitystrea.ms/schema/1.0/posthttp://activitystrea.ms/schema/1.0/posted0Gene Wiki and Wikimedia Foundation SPARQL workshop
/slideshow/gene-wiki-and-mediawiki-foundation-sparql-workshop/65835856
0yclehbxr62b22rc8r5q-signature-10bc0845f2943dd7378bd9ba7c9ce33897f38d17dd63d44c36dd29b81e79303b-poli-160908192118 Introduction to gene wiki project, the centralized model organism project and the use of SPARQL. ]]>
Introduction to gene wiki project, the centralized model organism project and the use of SPARQL. ]]>
Thu, 08 Sep 2016 19:21:17 GMT/slideshow/gene-wiki-and-mediawiki-foundation-sparql-workshop/65835856goodb@slideshare.net(goodb)Gene Wiki and Wikimedia Foundation SPARQL workshopgoodbIntroduction to gene wiki project, the centralized model organism project and the use of SPARQL. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/0yclehbxr62b22rc8r5q-signature-10bc0845f2943dd7378bd9ba7c9ce33897f38d17dd63d44c36dd29b81e79303b-poli-160908192118-thumbnail.jpg?width=120&height=120&fit=bounds" /><br> Introduction to gene wiki project, the centralized model organism project and the use of SPARQL.
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12764https://cdn.slidesharecdn.com/ss_thumbnails/0yclehbxr62b22rc8r5q-signature-10bc0845f2943dd7378bd9ba7c9ce33897f38d17dd63d44c36dd29b81e79303b-poli-160908192118-thumbnail.jpg?width=120&height=120&fit=boundspresentationBlackhttp://activitystrea.ms/schema/1.0/posthttp://activitystrea.ms/schema/1.0/posted0Opportunities and challenges presented by Wikidata in the context of biocuration
/slideshow/opportunities-and-challenges-presented-by-wikidata-in-the-context-of-biocuration/63827184
cecm9029ttcgrdicbucv-signature-0c8bc173267998f8f1d83d327f8a6b6012ae0acbe2bc704f99731aa7ae49a3fc-poli-160707220703 Abstract鈥擶ikidata is a world readable and writable knowledge base maintained by the Wikimedia Foundation. It offers the opportunity to collaboratively construct a fully open access knowledge graph spanning biology, medicine, and all other domains of knowledge. To meet this potential, social and technical challenges must be overcome - many of which are familiar to the biocuration community. These include community ontology building, high precision information extraction, provenance, and license management. By working together with Wikidata now, we can help shape it into a trustworthy, unencumbered central node in the Semantic Web of biomedical data.
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Abstract鈥擶ikidata is a world readable and writable knowledge base maintained by the Wikimedia Foundation. It offers the opportunity to collaboratively construct a fully open access knowledge graph spanning biology, medicine, and all other domains of knowledge. To meet this potential, social and technical challenges must be overcome - many of which are familiar to the biocuration community. These include community ontology building, high precision information extraction, provenance, and license management. By working together with Wikidata now, we can help shape it into a trustworthy, unencumbered central node in the Semantic Web of biomedical data.
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Thu, 07 Jul 2016 22:07:03 GMT/slideshow/opportunities-and-challenges-presented-by-wikidata-in-the-context-of-biocuration/63827184goodb@slideshare.net(goodb)Opportunities and challenges presented by Wikidata in the context of biocurationgoodbAbstract鈥擶ikidata is a world readable and writable knowledge base maintained by the Wikimedia Foundation. It offers the opportunity to collaboratively construct a fully open access knowledge graph spanning biology, medicine, and all other domains of knowledge. To meet this potential, social and technical challenges must be overcome - many of which are familiar to the biocuration community. These include community ontology building, high precision information extraction, provenance, and license management. By working together with Wikidata now, we can help shape it into a trustworthy, unencumbered central node in the Semantic Web of biomedical data.
<img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/cecm9029ttcgrdicbucv-signature-0c8bc173267998f8f1d83d327f8a6b6012ae0acbe2bc704f99731aa7ae49a3fc-poli-160707220703-thumbnail.jpg?width=120&height=120&fit=bounds" /><br> Abstract鈥擶ikidata is a world readable and writable knowledge base maintained by the Wikimedia Foundation. It offers the opportunity to collaboratively construct a fully open access knowledge graph spanning biology, medicine, and all other domains of knowledge. To meet this potential, social and technical challenges must be overcome - many of which are familiar to the biocuration community. These include community ontology building, high precision information extraction, provenance, and license management. By working together with Wikidata now, we can help shape it into a trustworthy, unencumbered central node in the Semantic Web of biomedical data.
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62309https://cdn.slidesharecdn.com/ss_thumbnails/cecm9029ttcgrdicbucv-signature-0c8bc173267998f8f1d83d327f8a6b6012ae0acbe2bc704f99731aa7ae49a3fc-poli-160707220703-thumbnail.jpg?width=120&height=120&fit=boundspresentationBlackhttp://activitystrea.ms/schema/1.0/posthttp://activitystrea.ms/schema/1.0/posted0Scripps bioinformatics seminar_day_2
/slideshow/scripps-bioinformatics-seminarday2/62702658
mhermy4lsookdqi6dhdq-signature-3fb35ed23d46d5ce32e8b8ba9cbfc96149fb5daa809e457c90df6f535c27891f-poli-160603172726 Part 2 of introduction to knowledge representation and applications for knowledge discovery in bioinformatics]]>
Part 2 of introduction to knowledge representation and applications for knowledge discovery in bioinformatics]]>
Fri, 03 Jun 2016 17:27:26 GMT/slideshow/scripps-bioinformatics-seminarday2/62702658goodb@slideshare.net(goodb)Scripps bioinformatics seminar_day_2goodbPart 2 of introduction to knowledge representation and applications for knowledge discovery in bioinformatics<img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/mhermy4lsookdqi6dhdq-signature-3fb35ed23d46d5ce32e8b8ba9cbfc96149fb5daa809e457c90df6f535c27891f-poli-160603172726-thumbnail.jpg?width=120&height=120&fit=bounds" /><br> Part 2 of introduction to knowledge representation and applications for knowledge discovery in bioinformatics
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33810https://cdn.slidesharecdn.com/ss_thumbnails/mhermy4lsookdqi6dhdq-signature-3fb35ed23d46d5ce32e8b8ba9cbfc96149fb5daa809e457c90df6f535c27891f-poli-160603172726-thumbnail.jpg?width=120&height=120&fit=boundspresentationBlackhttp://activitystrea.ms/schema/1.0/posthttp://activitystrea.ms/schema/1.0/posted0Computing on the shoulders of giants
/slideshow/computing-on-the-shoulders-of-giants/62583111
t4ssedhlqjey3gubzrcg-signature-1ff9e63e36e9d05e4581ee903475b496d2ebc097dd4158b0330d47700381c0d2-poli-160531163257 Computing on the shoulders of giants: how existing knowledge is represented and applied in bioinformatics.
A seminar for the TSRI graduate program.]]>
Computing on the shoulders of giants: how existing knowledge is represented and applied in bioinformatics.
A seminar for the TSRI graduate program.]]>
Tue, 31 May 2016 16:32:57 GMT/slideshow/computing-on-the-shoulders-of-giants/62583111goodb@slideshare.net(goodb)Computing on the shoulders of giantsgoodbComputing on the shoulders of giants: 锟絟ow existing knowledge is represented and applied in bioinformatics.
A seminar for the TSRI graduate program.<img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/t4ssedhlqjey3gubzrcg-signature-1ff9e63e36e9d05e4581ee903475b496d2ebc097dd4158b0330d47700381c0d2-poli-160531163257-thumbnail.jpg?width=120&height=120&fit=bounds" /><br> Computing on the shoulders of giants: 锟絟ow existing knowledge is represented and applied in bioinformatics.
A seminar for the TSRI graduate program.
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7348https://cdn.slidesharecdn.com/ss_thumbnails/t4ssedhlqjey3gubzrcg-signature-1ff9e63e36e9d05e4581ee903475b496d2ebc097dd4158b0330d47700381c0d2-poli-160531163257-thumbnail.jpg?width=120&height=120&fit=boundspresentationBlackhttp://activitystrea.ms/schema/1.0/posthttp://activitystrea.ms/schema/1.0/posted0Wikidata workshop for ISB Biocuration 2016
/slideshow/wikidata-workshop-for-isb-biocuration-2016/60855984
mkyyez0fqmuhcvbf0m1k-signature-7d782bf979f2efdb134f6c2d4e788a99259314a540eb0e187e17b9e796c6bf92-poli-160413094148 Intro to wikidata for life scientists]]>
Intro to wikidata for life scientists]]>
Wed, 13 Apr 2016 09:41:47 GMT/slideshow/wikidata-workshop-for-isb-biocuration-2016/60855984goodb@slideshare.net(goodb)Wikidata workshop for ISB Biocuration 2016goodbIntro to wikidata for life scientists<img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/mkyyez0fqmuhcvbf0m1k-signature-7d782bf979f2efdb134f6c2d4e788a99259314a540eb0e187e17b9e796c6bf92-poli-160413094148-thumbnail.jpg?width=120&height=120&fit=bounds" /><br> Intro to wikidata for life scientists
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6276https://cdn.slidesharecdn.com/ss_thumbnails/mkyyez0fqmuhcvbf0m1k-signature-7d782bf979f2efdb134f6c2d4e788a99259314a540eb0e187e17b9e796c6bf92-poli-160413094148-thumbnail.jpg?width=120&height=120&fit=boundspresentationBlackhttp://activitystrea.ms/schema/1.0/posthttp://activitystrea.ms/schema/1.0/posted0Channeling Collaborative Spirit
/slideshow/channeling-collaborative-spirit/58598065
ys3aez3pqq6rpt4qmbzw-signature-5a2d51d1d6e88a2a3d8d93188a21c558d41002fdd53105eadc19460d4591214e-poli-160223094936 The Stone Soups of Programmers (hackathons) and Data (WikiData). Presented at Heart BD2K PI meeting, EBI, Feb. 22, 2016]]>
The Stone Soups of Programmers (hackathons) and Data (WikiData). Presented at Heart BD2K PI meeting, EBI, Feb. 22, 2016]]>
Tue, 23 Feb 2016 09:49:36 GMT/slideshow/channeling-collaborative-spirit/58598065goodb@slideshare.net(goodb)Channeling Collaborative SpiritgoodbThe Stone Soups of Programmers (hackathons) and Data (WikiData). Presented at Heart BD2K PI meeting, EBI, Feb. 22, 2016<img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/ys3aez3pqq6rpt4qmbzw-signature-5a2d51d1d6e88a2a3d8d93188a21c558d41002fdd53105eadc19460d4591214e-poli-160223094936-thumbnail.jpg?width=120&height=120&fit=bounds" /><br> The Stone Soups of Programmers (hackathons) and Data (WikiData). Presented at Heart BD2K PI meeting, EBI, Feb. 22, 2016
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7005https://cdn.slidesharecdn.com/ss_thumbnails/ugdt1cbsr0itlor73ogz-signature-6023dda07b276d9dc10d2a401dccf8cc70e2c62a38e7245381f652a2bbe669fe-poli-160121065728-thumbnail.jpg?width=120&height=120&fit=boundspresentationBlackhttp://activitystrea.ms/schema/1.0/posthttp://activitystrea.ms/schema/1.0/posted0(Poster) Knowledge.Bio: an Interactive Tool for Literature-based Discovery
/slideshow/poster-knowledgebio-an-interactive-tool-for-literaturebased-discovery/54792003
knobio1bd2k112015v2-151105181433-lva1-app6892 PubMed now indexes roughly 25 million articles and is growing by more than a million per year. The scale of this 鈥淏ig Knowledge鈥� repository renders traditional, article-based modes of user interaction unsatisfactory, demanding new interfaces for integrating and summarizing widely distributed knowledge. Natural language processing (NLP) techniques coupled with rich user interfaces can help meet this demand, providing end-users with enhanced views into public knowledge, stimulating their ability to form new hypotheses.
Knowledge.Bio provides a Web interface for exploring the results from text-mining PubMed. It works with subject, predicate, object assertions (triples) extracted from individual abstracts and with predicted statistical associations between pairs of concepts. While agnostic to the NLP technology employed, the current implementation is loaded with triples from the SemRep-generated SemmedDB database and putative gene-disease pairs obtained using Leiden University Medical Center鈥檚 鈥業mplicitome鈥� technology.
Users of Knowledge.Bio begin by identifying a concept of interest using text search. Once a concept is identified, associated triples and concept-pairs are displayed in tables. These tables have text-based and semantic filters to help refine the list of triples to relations of interest. The user then selects relations for insertion into a personal knowledge graph implemented using cytoscape.js. The graph is used as a note-taking or 鈥榤ind-mapping鈥� structure that can be saved offline and then later reloaded into the application. Clicking on edges within a graph or on the 鈥榚vidence鈥� element of a triple displays the abstracts where that relation was detected, thus allowing the user to judge the veracity of the statement and to read the underlying articles.
Knowledge.Bio is a free, open-source application that can provide, deep, personal, concise, shareable views into the 鈥淏ig Knowledge鈥� scattered across the biomedical literature.
Application: http://knowledge.bio
Source code: https://bitbucket.org/sulab/kb1/
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PubMed now indexes roughly 25 million articles and is growing by more than a million per year. The scale of this 鈥淏ig Knowledge鈥� repository renders traditional, article-based modes of user interaction unsatisfactory, demanding new interfaces for integrating and summarizing widely distributed knowledge. Natural language processing (NLP) techniques coupled with rich user interfaces can help meet this demand, providing end-users with enhanced views into public knowledge, stimulating their ability to form new hypotheses.
Knowledge.Bio provides a Web interface for exploring the results from text-mining PubMed. It works with subject, predicate, object assertions (triples) extracted from individual abstracts and with predicted statistical associations between pairs of concepts. While agnostic to the NLP technology employed, the current implementation is loaded with triples from the SemRep-generated SemmedDB database and putative gene-disease pairs obtained using Leiden University Medical Center鈥檚 鈥業mplicitome鈥� technology.
Users of Knowledge.Bio begin by identifying a concept of interest using text search. Once a concept is identified, associated triples and concept-pairs are displayed in tables. These tables have text-based and semantic filters to help refine the list of triples to relations of interest. The user then selects relations for insertion into a personal knowledge graph implemented using cytoscape.js. The graph is used as a note-taking or 鈥榤ind-mapping鈥� structure that can be saved offline and then later reloaded into the application. Clicking on edges within a graph or on the 鈥榚vidence鈥� element of a triple displays the abstracts where that relation was detected, thus allowing the user to judge the veracity of the statement and to read the underlying articles.
Knowledge.Bio is a free, open-source application that can provide, deep, personal, concise, shareable views into the 鈥淏ig Knowledge鈥� scattered across the biomedical literature.
Application: http://knowledge.bio
Source code: https://bitbucket.org/sulab/kb1/
]]>
Thu, 05 Nov 2015 18:14:32 GMT/slideshow/poster-knowledgebio-an-interactive-tool-for-literaturebased-discovery/54792003goodb@slideshare.net(goodb)(Poster) Knowledge.Bio: an Interactive Tool for Literature-based Discovery goodbPubMed now indexes roughly 25 million articles and is growing by more than a million per year. The scale of this 鈥淏ig Knowledge鈥� repository renders traditional, article-based modes of user interaction unsatisfactory, demanding new interfaces for integrating and summarizing widely distributed knowledge. Natural language processing (NLP) techniques coupled with rich user interfaces can help meet this demand, providing end-users with enhanced views into public knowledge, stimulating their ability to form new hypotheses.
Knowledge.Bio provides a Web interface for exploring the results from text-mining PubMed. It works with subject, predicate, object assertions (triples) extracted from individual abstracts and with predicted statistical associations between pairs of concepts. While agnostic to the NLP technology employed, the current implementation is loaded with triples from the SemRep-generated SemmedDB database and putative gene-disease pairs obtained using Leiden University Medical Center鈥檚 鈥業mplicitome鈥� technology.
Users of Knowledge.Bio begin by identifying a concept of interest using text search. Once a concept is identified, associated triples and concept-pairs are displayed in tables. These tables have text-based and semantic filters to help refine the list of triples to relations of interest. The user then selects relations for insertion into a personal knowledge graph implemented using cytoscape.js. The graph is used as a note-taking or 鈥榤ind-mapping鈥� structure that can be saved offline and then later reloaded into the application. Clicking on edges within a graph or on the 鈥榚vidence鈥� element of a triple displays the abstracts where that relation was detected, thus allowing the user to judge the veracity of the statement and to read the underlying articles.
Knowledge.Bio is a free, open-source application that can provide, deep, personal, concise, shareable views into the 鈥淏ig Knowledge鈥� scattered across the biomedical literature.
Application: http://knowledge.bio
Source code: https://bitbucket.org/sulab/kb1/
<img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/knobio1bd2k112015v2-151105181433-lva1-app6892-thumbnail.jpg?width=120&height=120&fit=bounds" /><br> PubMed now indexes roughly 25 million articles and is growing by more than a million per year. The scale of this 鈥淏ig Knowledge鈥� repository renders traditional, article-based modes of user interaction unsatisfactory, demanding new interfaces for integrating and summarizing widely distributed knowledge. Natural language processing (NLP) techniques coupled with rich user interfaces can help meet this demand, providing end-users with enhanced views into public knowledge, stimulating their ability to form new hypotheses.
Knowledge.Bio provides a Web interface for exploring the results from text-mining PubMed. It works with subject, predicate, object assertions (triples) extracted from individual abstracts and with predicted statistical associations between pairs of concepts. While agnostic to the NLP technology employed, the current implementation is loaded with triples from the SemRep-generated SemmedDB database and putative gene-disease pairs obtained using Leiden University Medical Center鈥檚 鈥業mplicitome鈥� technology.
Users of Knowledge.Bio begin by identifying a concept of interest using text search. Once a concept is identified, associated triples and concept-pairs are displayed in tables. These tables have text-based and semantic filters to help refine the list of triples to relations of interest. The user then selects relations for insertion into a personal knowledge graph implemented using cytoscape.js. The graph is used as a note-taking or 鈥榤ind-mapping鈥� structure that can be saved offline and then later reloaded into the application. Clicking on edges within a graph or on the 鈥榚vidence鈥� element of a triple displays the abstracts where that relation was detected, thus allowing the user to judge the veracity of the statement and to read the underlying articles.
Knowledge.Bio is a free, open-source application that can provide, deep, personal, concise, shareable views into the 鈥淏ig Knowledge鈥� scattered across the biomedical literature.
Application: http://knowledge.bio
Source code: https://bitbucket.org/sulab/kb1/
]]>
9068https://cdn.slidesharecdn.com/ss_thumbnails/knobio1bd2k112015v2-151105181433-lva1-app6892-thumbnail.jpg?width=120&height=120&fit=boundspresentationBlackhttp://activitystrea.ms/schema/1.0/posthttp://activitystrea.ms/schema/1.0/posted0Gene Wiki and Mark2Cure update for BD2K
/slideshow/gene-wiki-and-mark2cure-update-for-bd2k/51223887
20150417bd2kgenewikimark2cure-150803153252-lva1-app6892 An introduction to the Gene Wiki project with an emphasis on the use of the new WikiData project. Also describes mark2cure, a citizen science initiative oriented on biomedical text mining. ]]>
An introduction to the Gene Wiki project with an emphasis on the use of the new WikiData project. Also describes mark2cure, a citizen science initiative oriented on biomedical text mining. ]]>
Mon, 03 Aug 2015 15:32:52 GMT/slideshow/gene-wiki-and-mark2cure-update-for-bd2k/51223887goodb@slideshare.net(goodb)Gene Wiki and Mark2Cure update for BD2KgoodbAn introduction to the Gene Wiki project with an emphasis on the use of the new WikiData project. Also describes mark2cure, a citizen science initiative oriented on biomedical text mining. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/20150417bd2kgenewikimark2cure-150803153252-lva1-app6892-thumbnail.jpg?width=120&height=120&fit=bounds" /><br> An introduction to the Gene Wiki project with an emphasis on the use of the new WikiData project. Also describes mark2cure, a citizen science initiative oriented on biomedical text mining.
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6766https://cdn.slidesharecdn.com/ss_thumbnails/20150417bd2kgenewikimark2cure-150803153252-lva1-app6892-thumbnail.jpg?width=120&height=120&fit=boundspresentationBlackhttp://activitystrea.ms/schema/1.0/posthttp://activitystrea.ms/schema/1.0/posted02015 6 bd2k_biobranch_knowbio
/slideshow/2015-6-bd2kbiobranchknowbio/51143798
20156bd2kbiobranchknowbio-150731143408-lva1-app6891 Update on the gene wiki project, introduction to knowledge.bio semantic search application, introduction to biobranch.org collaborative decision tree creator]]>
Update on the gene wiki project, introduction to knowledge.bio semantic search application, introduction to biobranch.org collaborative decision tree creator]]>
Fri, 31 Jul 2015 14:34:08 GMT/slideshow/2015-6-bd2kbiobranchknowbio/51143798goodb@slideshare.net(goodb)2015 6 bd2k_biobranch_knowbiogoodbUpdate on the gene wiki project, introduction to knowledge.bio semantic search application, introduction to biobranch.org collaborative decision tree creator<img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/20156bd2kbiobranchknowbio-150731143408-lva1-app6891-thumbnail.jpg?width=120&height=120&fit=bounds" /><br> Update on the gene wiki project, introduction to knowledge.bio semantic search application, introduction to biobranch.org collaborative decision tree creator
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5477https://cdn.slidesharecdn.com/ss_thumbnails/20156bd2kbiobranchknowbio-150731143408-lva1-app6891-thumbnail.jpg?width=120&height=120&fit=boundspresentationBlackhttp://activitystrea.ms/schema/1.0/posthttp://activitystrea.ms/schema/1.0/posted0(Bio)Hackathons
/slideshow/hackathon-bd2k2015-pdf/44584005
hackathonbd2k2015pdf-150212021603-conversion-gate01 A what, why and how description of hackathons for bioinformatics]]>
A what, why and how description of hackathons for bioinformatics]]>
Thu, 12 Feb 2015 02:16:03 GMT/slideshow/hackathon-bd2k2015-pdf/44584005goodb@slideshare.net(goodb)(Bio)HackathonsgoodbA what, why and how description of hackathons for bioinformatics<img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/hackathonbd2k2015pdf-150212021603-conversion-gate01-thumbnail.jpg?width=120&height=120&fit=bounds" /><br> A what, why and how description of hackathons for bioinformatics
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6533https://cdn.slidesharecdn.com/ss_thumbnails/hackathonbd2k2015pdf-150212021603-conversion-gate01-thumbnail.jpg?width=120&height=120&fit=boundspresentationBlackhttp://activitystrea.ms/schema/1.0/posthttp://activitystrea.ms/schema/1.0/posted0Citizen sciencepanel2015 pdf
/slideshow/citizen-sciencepanel2015-pdf/44582430
citizensciencepanel2015pdf-150212011224-conversion-gate01 Experiences and opportunities for citizen science in biomedical science. Talk given at #CitSci2015 citizen science conference panel.]]>
Experiences and opportunities for citizen science in biomedical science. Talk given at #CitSci2015 citizen science conference panel.]]>
Thu, 12 Feb 2015 01:12:24 GMT/slideshow/citizen-sciencepanel2015-pdf/44582430goodb@slideshare.net(goodb)Citizen sciencepanel2015 pdfgoodbExperiences and opportunities for citizen science in biomedical science. Talk given at #CitSci2015 citizen science conference panel.<img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/citizensciencepanel2015pdf-150212011224-conversion-gate01-thumbnail.jpg?width=120&height=120&fit=bounds" /><br> Experiences and opportunities for citizen science in biomedical science. Talk given at #CitSci2015 citizen science conference panel.
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6766https://cdn.slidesharecdn.com/ss_thumbnails/citizensciencepanel2015pdf-150212011224-conversion-gate01-thumbnail.jpg?width=120&height=120&fit=boundspresentationBlackhttp://activitystrea.ms/schema/1.0/posthttp://activitystrea.ms/schema/1.0/posted0https://cdn.slidesharecdn.com/profile-photo-goodb-48x48.jpg?cb=1727470129I study and build systems that use the World Wide Web to advance biomedical research.
Specialties: semantic web, ontology, OWL, machine learning, crowdsourcing, wikis, citizen science, natural language processing, knowledge basesi9606.blogspot.comhttps://cdn.slidesharecdn.com/ss_thumbnails/representingandreasoningwithbiologicalknowledge-us2ts-2019-190313004306-thumbnail.jpg?width=320&height=320&fit=boundsslideshow/representing-and-reasoning-with-biological-knowledge/135979348Representing and reaso...https://cdn.slidesharecdn.com/ss_thumbnails/good-pathways2go-rockyaspen-2018-powerpoint-181208004827-thumbnail.jpg?width=320&height=320&fit=boundsgoodb/integrating-pathway-databases-with-gene-ontology-causal-activity-modelsIntegrating Pathway Da...https://cdn.slidesharecdn.com/ss_thumbnails/pathways2go-gocnyu2018-180522042203-thumbnail.jpg?width=320&height=320&fit=boundsslideshow/pathways2go-converting-biopax-pathways-to-gocams/98000547Pathways2GO: Convertin...