際際滷shows by User: lukelightning / http://www.slideshare.net/images/logo.gif 際際滷shows by User: lukelightning / Tue, 12 Mar 2013 18:26:53 GMT 際際滷Share feed for 際際滷shows by User: lukelightning Human esterases: Chemical and Biochemical Considerations /slideshow/human-esterases-chemical-and-biochemical-considerations/17146321 humanesterases-130312182653-phpapp02
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]]> Tue, 12 Mar 2013 18:26:53 GMT /slideshow/human-esterases-chemical-and-biochemical-considerations/17146321 lukelightning@slideshare.net(lukelightning) Human esterases: Chemical and Biochemical Considerations lukelightning <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/humanesterases-130312182653-phpapp02-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br>
Human esterases: Chemical and Biochemical Considerations from Luke Lightning
]]> 12275 8 https://cdn.slidesharecdn.com/ss_thumbnails/humanesterases-130312182653-phpapp02-thumbnail.jpg?width=120&height=120&fit=bounds presentation Black http://activitystrea.ms/schema/1.0/post http://activitystrea.ms/schema/1.0/posted 0 Hydrolysis of pyrethroids by human and rat tissues /slideshow/hydrolysis-of-pyrethroids-by-human-and-rat-tissues/17146174 hydrolysisofpyrethroidsbyhumanandrattissues-130312181837-phpapp02
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]]> Tue, 12 Mar 2013 18:18:37 GMT /slideshow/hydrolysis-of-pyrethroids-by-human-and-rat-tissues/17146174 lukelightning@slideshare.net(lukelightning) Hydrolysis of pyrethroids by human and rat tissues lukelightning <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/hydrolysisofpyrethroidsbyhumanandrattissues-130312181837-phpapp02-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br>
Hydrolysis of pyrethroids by human and rat tissues from Luke Lightning
]]> 1001 4 https://cdn.slidesharecdn.com/ss_thumbnails/hydrolysisofpyrethroidsbyhumanandrattissues-130312181837-phpapp02-thumbnail.jpg?width=120&height=120&fit=bounds presentation Black http://activitystrea.ms/schema/1.0/post http://activitystrea.ms/schema/1.0/posted 0 Mass spectrometric analysis of cyp450s following mechanism based inactivation Lightning 2012 /slideshow/mass-spectrometric-analysis-of-cyp450s-following-mechanism-based-inactivation-lightning-2012/13649501 massspectrometricanalysisofcyp450sfollowingmechanismbasedinactivationlightning2012-120715195813-phpapp01
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]]> Sun, 15 Jul 2012 19:58:12 GMT /slideshow/mass-spectrometric-analysis-of-cyp450s-following-mechanism-based-inactivation-lightning-2012/13649501 lukelightning@slideshare.net(lukelightning) Mass spectrometric analysis of cyp450s following mechanism based inactivation Lightning 2012 lukelightning <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/massspectrometricanalysisofcyp450sfollowingmechanismbasedinactivationlightning2012-120715195813-phpapp01-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br>
Mass spectrometric analysis of cyp450s following mechanism based inactivation Lightning 2012 from Luke Lightning
]]> 595 3 https://cdn.slidesharecdn.com/ss_thumbnails/massspectrometricanalysisofcyp450sfollowingmechanismbasedinactivationlightning2012-120715195813-phpapp01-thumbnail.jpg?width=120&height=120&fit=bounds presentation White http://activitystrea.ms/schema/1.0/post http://activitystrea.ms/schema/1.0/posted 0 Lightning Deloitte Patheon QB3 Talk 2012 /slideshow/lightning-deloitte-patheon-qb3-talk-2012/13491372 lightningdeloittepatheonqb3talk2012-120629030727-phpapp01
Luke Lightning, ADME DMPK PKPD startups FDA ]]>
Luke Lightning, ADME DMPK PKPD startups FDA ]]> Fri, 29 Jun 2012 03:07:26 GMT /slideshow/lightning-deloitte-patheon-qb3-talk-2012/13491372 lukelightning@slideshare.net(lukelightning) Lightning Deloitte Patheon QB3 Talk 2012 lukelightning Luke Lightning, ADME DMPK PKPD startups FDA <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/lightningdeloittepatheonqb3talk2012-120629030727-phpapp01-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> Luke Lightning, ADME DMPK PKPD startups FDA
Lightning Deloitte Patheon QB3 Talk 2012 from Luke Lightning
]]> 843 8 https://cdn.slidesharecdn.com/ss_thumbnails/lightningdeloittepatheonqb3talk2012-120629030727-phpapp01-thumbnail.jpg?width=120&height=120&fit=bounds presentation White http://activitystrea.ms/schema/1.0/post http://activitystrea.ms/schema/1.0/posted 0 CYP2C9 Haplotype Structure and Association with Clinical Outcomes /slideshow/cyp2c9-haplotype-structure-and-association-with-clinical-outcomes/12736995 cyp2c9haplotypestructureandassociationwithclinicaloutcomes-120429133542-phpapp02
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]]> Sun, 29 Apr 2012 13:35:41 GMT /slideshow/cyp2c9-haplotype-structure-and-association-with-clinical-outcomes/12736995 lukelightning@slideshare.net(lukelightning) CYP2C9 Haplotype Structure and Association with Clinical Outcomes lukelightning <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/cyp2c9haplotypestructureandassociationwithclinicaloutcomes-120429133542-phpapp02-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br>
CYP2C9 Haplotype Structure and Association with Clinical Outcomes from Luke Lightning
]]> 2230 6 https://cdn.slidesharecdn.com/ss_thumbnails/cyp2c9haplotypestructureandassociationwithclinicaloutcomes-120429133542-phpapp02-thumbnail.jpg?width=120&height=120&fit=bounds presentation Black http://activitystrea.ms/schema/1.0/post http://activitystrea.ms/schema/1.0/posted 0 Butyrylcholinesterase Overview: Substrates Inhibitors Structure Mechanism Therapeutic Indications /slideshow/butyrylcholinesterase-overview-substrates-inhibitors-structure-mechanism-therapeutic-indications/12736760 butyrylcholinesteraseoverview-substratesinhibitorstherapeuticindications-120429131023-phpapp01
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]]> Sun, 29 Apr 2012 13:10:20 GMT /slideshow/butyrylcholinesterase-overview-substrates-inhibitors-structure-mechanism-therapeutic-indications/12736760 lukelightning@slideshare.net(lukelightning) Butyrylcholinesterase Overview: Substrates Inhibitors Structure Mechanism Therapeutic Indications lukelightning <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/butyrylcholinesteraseoverview-substratesinhibitorstherapeuticindications-120429131023-phpapp01-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br>
Butyrylcholinesterase Overview: Substrates Inhibitors Structure Mechanism Therapeutic Indications from Luke Lightning
]]> 10728 5 https://cdn.slidesharecdn.com/ss_thumbnails/butyrylcholinesteraseoverview-substratesinhibitorstherapeuticindications-120429131023-phpapp01-thumbnail.jpg?width=120&height=120&fit=bounds presentation Black http://activitystrea.ms/schema/1.0/post http://activitystrea.ms/schema/1.0/posted 0 Involvement of multiple P450s and UDP-GTs in the in vitro metabolism of Muraglitazar /slideshow/involvement-of-multiple-p450s-and-udpgts-in-the-in-vitro-metabolism-of-muraglitazar/12529896 involvementofmultiplep450sandudp-gtsintheinvitrometabolismofmuraglitazar-120413121034-phpapp01
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]]> Fri, 13 Apr 2012 12:10:31 GMT /slideshow/involvement-of-multiple-p450s-and-udpgts-in-the-in-vitro-metabolism-of-muraglitazar/12529896 lukelightning@slideshare.net(lukelightning) Involvement of multiple P450s and UDP-GTs in the in vitro metabolism of Muraglitazar lukelightning <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/involvementofmultiplep450sandudp-gtsintheinvitrometabolismofmuraglitazar-120413121034-phpapp01-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br>
Involvement of multiple P450s and UDP-GTs in the in vitro metabolism of Muraglitazar from Luke Lightning
]]> 590 4 https://cdn.slidesharecdn.com/ss_thumbnails/involvementofmultiplep450sandudp-gtsintheinvitrometabolismofmuraglitazar-120413121034-phpapp01-thumbnail.jpg?width=120&height=120&fit=bounds document Black http://activitystrea.ms/schema/1.0/post http://activitystrea.ms/schema/1.0/posted 0 Microscale culture of human liver cells for drug development /slideshow/microscale-culture-of-human-liver-cells-for-drug-development/12309971 microscalecultureofhumanlivercellsfordrugdevelopment-120407144920-phpapp02
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]]> Sat, 07 Apr 2012 14:49:18 GMT /slideshow/microscale-culture-of-human-liver-cells-for-drug-development/12309971 lukelightning@slideshare.net(lukelightning) Microscale culture of human liver cells for drug development lukelightning <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/microscalecultureofhumanlivercellsfordrugdevelopment-120407144920-phpapp02-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br>
Microscale culture of human liver cells for drug development from Luke Lightning
]]> 1490 5 https://cdn.slidesharecdn.com/ss_thumbnails/microscalecultureofhumanlivercellsfordrugdevelopment-120407144920-phpapp02-thumbnail.jpg?width=120&height=120&fit=bounds presentation Black http://activitystrea.ms/schema/1.0/post http://activitystrea.ms/schema/1.0/posted 0 Introduction to pharmacology and drug metabolism /slideshow/introduction-to-pharmacology-and-drug-metabolism/12249301 introductiontopharmacologyanddrugmetabolism-120401180053-phpapp02
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]]> Sun, 01 Apr 2012 18:00:51 GMT /slideshow/introduction-to-pharmacology-and-drug-metabolism/12249301 lukelightning@slideshare.net(lukelightning) Introduction to pharmacology and drug metabolism lukelightning <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/introductiontopharmacologyanddrugmetabolism-120401180053-phpapp02-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br>
Introduction to pharmacology and drug metabolism from Luke Lightning
]]> 11639 9 https://cdn.slidesharecdn.com/ss_thumbnails/introductiontopharmacologyanddrugmetabolism-120401180053-phpapp02-thumbnail.jpg?width=120&height=120&fit=bounds presentation Black http://activitystrea.ms/schema/1.0/post http://activitystrea.ms/schema/1.0/posted 0 Osteoporosis Therapy Overview /slideshow/osteoporosis-therapy-overview/12249216 osteoporosis-120401175440-phpapp01
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]]> Sun, 01 Apr 2012 17:54:39 GMT /slideshow/osteoporosis-therapy-overview/12249216 lukelightning@slideshare.net(lukelightning) Osteoporosis Therapy Overview lukelightning <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/osteoporosis-120401175440-phpapp01-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br>
Osteoporosis Therapy Overview from Luke Lightning
]]> 3930 10 https://cdn.slidesharecdn.com/ss_thumbnails/osteoporosis-120401175440-phpapp01-thumbnail.jpg?width=120&height=120&fit=bounds presentation Black http://activitystrea.ms/schema/1.0/post http://activitystrea.ms/schema/1.0/posted 0 Molecular analysis of whole body animal tissue secitions by imaging maldi ms /lukelightning/molecular-analysis-of-whole-body-animal-tissue-secitions-by-imaging-maldi-ms molecularanalysisofwholebodyanimaltissuesecitionsbyimagingmaldi-ms-120401111538-phpapp01
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]]> Sun, 01 Apr 2012 11:15:37 GMT /lukelightning/molecular-analysis-of-whole-body-animal-tissue-secitions-by-imaging-maldi-ms lukelightning@slideshare.net(lukelightning) Molecular analysis of whole body animal tissue secitions by imaging maldi ms lukelightning <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/molecularanalysisofwholebodyanimaltissuesecitionsbyimagingmaldi-ms-120401111538-phpapp01-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br>
Molecular analysis of whole body animal tissue secitions by imaging maldi ms from Luke Lightning
]]> 695 2 https://cdn.slidesharecdn.com/ss_thumbnails/molecularanalysisofwholebodyanimaltissuesecitionsbyimagingmaldi-ms-120401111538-phpapp01-thumbnail.jpg?width=120&height=120&fit=bounds presentation Black http://activitystrea.ms/schema/1.0/post http://activitystrea.ms/schema/1.0/posted 0 Kinetics of glyburide metabolism by humans and baboons using liver and placental tissues /slideshow/kinetics-of-glyburide-metabolism-by-humans-and-baboons-using-liver-and-placental-tissues/12238232 kineticsofglyburidemetabolismbyhumansandbaboonsusingliverandplacentaltissues-120331201321-phpapp02
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]]> Sat, 31 Mar 2012 20:13:20 GMT /slideshow/kinetics-of-glyburide-metabolism-by-humans-and-baboons-using-liver-and-placental-tissues/12238232 lukelightning@slideshare.net(lukelightning) Kinetics of glyburide metabolism by humans and baboons using liver and placental tissues lukelightning <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/kineticsofglyburidemetabolismbyhumansandbaboonsusingliverandplacentaltissues-120331201321-phpapp02-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br>
Kinetics of glyburide metabolism by humans and baboons using liver and placental tissues from Luke Lightning
]]> 1255 7 https://cdn.slidesharecdn.com/ss_thumbnails/kineticsofglyburidemetabolismbyhumansandbaboonsusingliverandplacentaltissues-120331201321-phpapp02-thumbnail.jpg?width=120&height=120&fit=bounds presentation Black http://activitystrea.ms/schema/1.0/post http://activitystrea.ms/schema/1.0/posted 0 https://cdn.slidesharecdn.com/profile-photo-lukelightning-48x48.jpg?cb=1666155076 15+ years in biotech and pharma profession: Research and Development team leader Preclinical PK and bioanalytical study administrator: designed preclinical DMPK and bioanalytical protocols implemented by CROs that allowed for go/no go decisions within budget Early discovery, preclinical and clinical team experience: worked on early discovery and preclinical project teams as well as on programs involving Phase 1 and Phase 2 clinical candidates Managed DMPK programs running concurrently in several therapeutic areas: cardiovascular, gastrointestinal, antiviral, and neurological disorders Entrepreneurial spirit: identified new potential therapeutic opportunities for... http://alquest.us/ https://cdn.slidesharecdn.com/ss_thumbnails/humanesterases-130312182653-phpapp02-thumbnail.jpg?width=320&height=320&fit=bounds slideshow/human-esterases-chemical-and-biochemical-considerations/17146321 Human esterases: Chemi... https://cdn.slidesharecdn.com/ss_thumbnails/hydrolysisofpyrethroidsbyhumanandrattissues-130312181837-phpapp02-thumbnail.jpg?width=320&height=320&fit=bounds slideshow/hydrolysis-of-pyrethroids-by-human-and-rat-tissues/17146174 Hydrolysis of pyrethro... https://cdn.slidesharecdn.com/ss_thumbnails/massspectrometricanalysisofcyp450sfollowingmechanismbasedinactivationlightning2012-120715195813-phpapp01-thumbnail.jpg?width=320&height=320&fit=bounds slideshow/mass-spectrometric-analysis-of-cyp450s-following-mechanism-based-inactivation-lightning-2012/13649501 Mass spectrometric ana...