際際滷shows by User: mortazavi / http://www.slideshare.net/images/logo.gif 際際滷shows by User: mortazavi / Fri, 21 Oct 2022 05:16:13 GMT 際際滷Share feed for 際際滷shows by User: mortazavi Mercury Released from Dental Amalgam Fillings in Response to Different Physical Stressors /slideshow/mercury-released-from-dental-amalgam-fillings-in-response-to-different-physical-stressorspptx/253740743 mercuryreleasedfromdentalamalgamfillingsinresponsetodifferentphysicalstressors-221021051614-c057b534
Approximately 50% of dental amalgam is elemental mercury by weight. Accumulating body of evidence now shows that not only static magnetic fields (SMF) but both ionizing and non-ionizing electromagnetic radiations can increase the rate of mercury release from dental amalgam fillings. Iranian scientists firstly addressed this issue in 2008 but more than 10 years later, it became viral worldwide after BBC released a report on this issue.]]>
Approximately 50% of dental amalgam is elemental mercury by weight. Accumulating body of evidence now shows that not only static magnetic fields (SMF) but both ionizing and non-ionizing electromagnetic radiations can increase the rate of mercury release from dental amalgam fillings. Iranian scientists firstly addressed this issue in 2008 but more than 10 years later, it became viral worldwide after BBC released a report on this issue.]]> Fri, 21 Oct 2022 05:16:13 GMT /slideshow/mercury-released-from-dental-amalgam-fillings-in-response-to-different-physical-stressorspptx/253740743 mortazavi@slideshare.net(mortazavi) Mercury Released from Dental Amalgam Fillings in Response to Different Physical Stressors mortazavi Approximately 50% of dental amalgam is elemental mercury by weight. Accumulating body of evidence now shows that not only static magnetic fields (SMF) but both ionizing and non-ionizing electromagnetic radiations can increase the rate of mercury release from dental amalgam fillings. Iranian scientists firstly addressed this issue in 2008 but more than 10 years later, it became viral worldwide after BBC released a report on this issue. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/mercuryreleasedfromdentalamalgamfillingsinresponsetodifferentphysicalstressors-221021051614-c057b534-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> Approximately 50% of dental amalgam is elemental mercury by weight. Accumulating body of evidence now shows that not only static magnetic fields (SMF) but both ionizing and non-ionizing electromagnetic radiations can increase the rate of mercury release from dental amalgam fillings. Iranian scientists firstly addressed this issue in 2008 but more than 10 years later, it became viral worldwide after BBC released a report on this issue.
Mercury Released from Dental Amalgam Fillings in Response to Different Physical Stressors from SMJ Mortazavi
]]> 77 0 https://cdn.slidesharecdn.com/ss_thumbnails/mercuryreleasedfromdentalamalgamfillingsinresponsetodifferentphysicalstressors-221021051614-c057b534-thumbnail.jpg?width=120&height=120&fit=bounds presentation Black http://activitystrea.ms/schema/1.0/post http://activitystrea.ms/schema/1.0/posted 0 Low-Dose Radiation Therapy for COVID-19 -Time reveals the truth.pptx /slideshow/lowdose-radiation-therapy-for-covid19-time-reveals-the-truthpptx/252160845 revisedupdated-low-doseradiationtherapyforcovid-19-timerevealsthetruth-220711152931-f2bdac0b
More than two years ago, we warned about the dangers of treatment methods that are based on the use of antivirals, but it took a long time for the issue of selective pressure caused by antivirals to be widely discussed in scientific societies. Now the Science report published on June 29, 2022 clearly points to this issue]]>
More than two years ago, we warned about the dangers of treatment methods that are based on the use of antivirals, but it took a long time for the issue of selective pressure caused by antivirals to be widely discussed in scientific societies. Now the Science report published on June 29, 2022 clearly points to this issue]]> Mon, 11 Jul 2022 15:29:31 GMT /slideshow/lowdose-radiation-therapy-for-covid19-time-reveals-the-truthpptx/252160845 mortazavi@slideshare.net(mortazavi) Low-Dose Radiation Therapy for COVID-19 -Time reveals the truth.pptx mortazavi More than two years ago, we warned about the dangers of treatment methods that are based on the use of antivirals, but it took a long time for the issue of selective pressure caused by antivirals to be widely discussed in scientific societies. Now the Science report published on June 29, 2022 clearly points to this issue <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/revisedupdated-low-doseradiationtherapyforcovid-19-timerevealsthetruth-220711152931-f2bdac0b-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> More than two years ago, we warned about the dangers of treatment methods that are based on the use of antivirals, but it took a long time for the issue of selective pressure caused by antivirals to be widely discussed in scientific societies. Now the Science report published on June 29, 2022 clearly points to this issue
Low-Dose Radiation Therapy for COVID-19 -Time reveals the truth.pptx from SMJ Mortazavi
]]> 219 0 https://cdn.slidesharecdn.com/ss_thumbnails/revisedupdated-low-doseradiationtherapyforcovid-19-timerevealsthetruth-220711152931-f2bdac0b-thumbnail.jpg?width=120&height=120&fit=bounds presentation Black http://activitystrea.ms/schema/1.0/post http://activitystrea.ms/schema/1.0/posted 0 Time reveals the truth.pdf /slideshow/time-reveals-the-truthpdf/252153194 timerevealsthetruth-220710052312-ade0cbbc
More than two years ago, we warned about the dangers of treatment methods that are based on the use of antivirals, but it took a long time for the issue of selective pressure caused by antivirals to be widely discussed in scientific societies. Now the Science report published on June 29, 2022 clearly points to this issue.]]>
More than two years ago, we warned about the dangers of treatment methods that are based on the use of antivirals, but it took a long time for the issue of selective pressure caused by antivirals to be widely discussed in scientific societies. Now the Science report published on June 29, 2022 clearly points to this issue.]]> Sun, 10 Jul 2022 05:23:12 GMT /slideshow/time-reveals-the-truthpdf/252153194 mortazavi@slideshare.net(mortazavi) Time reveals the truth.pdf mortazavi More than two years ago, we warned about the dangers of treatment methods that are based on the use of antivirals, but it took a long time for the issue of selective pressure caused by antivirals to be widely discussed in scientific societies. Now the Science report published on June 29, 2022 clearly points to this issue. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/timerevealsthetruth-220710052312-ade0cbbc-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> More than two years ago, we warned about the dangers of treatment methods that are based on the use of antivirals, but it took a long time for the issue of selective pressure caused by antivirals to be widely discussed in scientific societies. Now the Science report published on June 29, 2022 clearly points to this issue.
Time reveals the truth.pdf from SMJ Mortazavi
]]> 29 0 https://cdn.slidesharecdn.com/ss_thumbnails/timerevealsthetruth-220710052312-ade0cbbc-thumbnail.jpg?width=120&height=120&fit=bounds presentation Black http://activitystrea.ms/schema/1.0/post http://activitystrea.ms/schema/1.0/posted 0 Final-How Some INIRPRCs Studies Can Re-Route the Direction of Global Science (2).pdf /slideshow/finalhow-some-inirprcs-studies-can-reroute-the-direction-of-global-science-2pdf/252142423 final-howsomeinirprcsstudiescanre-routethedirectionofglobalscience2-220707200330-fc0fe398
In this presentation some of the game changer achievements of the Ionizing and Non-Ionizing Radiation Protection Research Center (INIRPRC) in the following fields are discussed: 1. Space Biology 2. COVID-19 Management 3. Ramsar high background radiation areas (HBRAs) Studies 4. Health Effects of Radiofrequency Radiation]]>
In this presentation some of the game changer achievements of the Ionizing and Non-Ionizing Radiation Protection Research Center (INIRPRC) in the following fields are discussed: 1. Space Biology 2. COVID-19 Management 3. Ramsar high background radiation areas (HBRAs) Studies 4. Health Effects of Radiofrequency Radiation]]> Thu, 07 Jul 2022 20:03:29 GMT /slideshow/finalhow-some-inirprcs-studies-can-reroute-the-direction-of-global-science-2pdf/252142423 mortazavi@slideshare.net(mortazavi) Final-How Some INIRPRCs Studies Can Re-Route the Direction of Global Science (2).pdf mortazavi In this presentation some of the game changer achievements of the Ionizing and Non-Ionizing Radiation Protection Research Center (INIRPRC) in the following fields are discussed: 1. Space Biology 2. COVID-19 Management 3. Ramsar high background radiation areas (HBRAs) Studies 4. Health Effects of Radiofrequency Radiation <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/final-howsomeinirprcsstudiescanre-routethedirectionofglobalscience2-220707200330-fc0fe398-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> In this presentation some of the game changer achievements of the Ionizing and Non-Ionizing Radiation Protection Research Center (INIRPRC) in the following fields are discussed: 1. Space Biology 2. COVID-19 Management 3. Ramsar high background radiation areas (HBRAs) Studies 4. Health Effects of Radiofrequency Radiation
Final-How Some INIRPRCs Studies Can Re-Route the Direction of Global Science (2).pdf from SMJ Mortazavi
]]> 20 0 https://cdn.slidesharecdn.com/ss_thumbnails/final-howsomeinirprcsstudiescanre-routethedirectionofglobalscience2-220707200330-fc0fe398-thumbnail.jpg?width=120&height=120&fit=bounds presentation Black http://activitystrea.ms/schema/1.0/post http://activitystrea.ms/schema/1.0/posted 0 How Crucial is the Importance of COVID-19 in Long-Term Space Missions? /mortazavi/covid19-in-space-missions covidinspacepresentation1-211207070520
How Crucial is the Importance of COVID-19 in Long-Term Space Missions? The higher fatality of COVID-19 infections in space is due to: 1) impossibility to use the so-called social distancing due to microgravity 2) immune system dysregulation 3) possibly higher mutation rates of the SARS-CoV-2 as an RNA virus 4) higher risk of reactivation of the virus 5) existence of strong selective pressure and 6) decreased maximum oxygen uptake. ]]>
How Crucial is the Importance of COVID-19 in Long-Term Space Missions? The higher fatality of COVID-19 infections in space is due to: 1) impossibility to use the so-called social distancing due to microgravity 2) immune system dysregulation 3) possibly higher mutation rates of the SARS-CoV-2 as an RNA virus 4) higher risk of reactivation of the virus 5) existence of strong selective pressure and 6) decreased maximum oxygen uptake. ]]> Tue, 07 Dec 2021 07:05:20 GMT /mortazavi/covid19-in-space-missions mortazavi@slideshare.net(mortazavi) How Crucial is the Importance of COVID-19 in Long-Term Space Missions? mortazavi How Crucial is the Importance of COVID-19 in Long-Term Space Missions? The higher fatality of COVID-19 infections in space is due to: 1) impossibility to use the so-called social distancing due to microgravity 2) immune system dysregulation 3) possibly higher mutation rates of the SARS-CoV-2 as an RNA virus 4) higher risk of reactivation of the virus 5) existence of strong selective pressure and 6) decreased maximum oxygen uptake. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/covidinspacepresentation1-211207070520-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> How Crucial is the Importance of COVID-19 in Long-Term Space Missions? The higher fatality of COVID-19 infections in space is due to: 1) impossibility to use the so-called social distancing due to microgravity 2) immune system dysregulation 3) possibly higher mutation rates of the SARS-CoV-2 as an RNA virus 4) higher risk of reactivation of the virus 5) existence of strong selective pressure and 6) decreased maximum oxygen uptake.
How Crucial is the Importance of COVID-19 in Long-Term Space Missions? from SMJ Mortazavi
]]> 22 0 https://cdn.slidesharecdn.com/ss_thumbnails/covidinspacepresentation1-211207070520-thumbnail.jpg?width=120&height=120&fit=bounds presentation Black http://activitystrea.ms/schema/1.0/post http://activitystrea.ms/schema/1.0/posted 0 Why it is of paramount importance to know the source of funding in emf research revisiting 5 g issue /slideshow/why-it-is-of-paramount-importance-to-know-the-source-of-funding-in-emf-research-revisiting-5-g-issue/248368358 whyitisofparamountimportancetoknowthesourceoffundinginemfresearch-revisiting5gissue-210520101709
Invited Talk - 1st International Conference on Bioelectromagnetics (INICBEM-2021), May 18-19, 2021 ]]>
Invited Talk - 1st International Conference on Bioelectromagnetics (INICBEM-2021), May 18-19, 2021 ]]> Thu, 20 May 2021 10:17:09 GMT /slideshow/why-it-is-of-paramount-importance-to-know-the-source-of-funding-in-emf-research-revisiting-5-g-issue/248368358 mortazavi@slideshare.net(mortazavi) Why it is of paramount importance to know the source of funding in emf research revisiting 5 g issue mortazavi Invited Talk - 1st International Conference on Bioelectromagnetics (INICBEM-2021), May 18-19, 2021 <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/whyitisofparamountimportancetoknowthesourceoffundinginemfresearch-revisiting5gissue-210520101709-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> Invited Talk - 1st International Conference on Bioelectromagnetics (INICBEM-2021), May 18-19, 2021
Why it is of paramount importance to know the source of funding in emf research revisiting 5 g issue from SMJ Mortazavi
]]> 29 0 https://cdn.slidesharecdn.com/ss_thumbnails/whyitisofparamountimportancetoknowthesourceoffundinginemfresearch-revisiting5gissue-210520101709-thumbnail.jpg?width=120&height=120&fit=bounds presentation Black http://activitystrea.ms/schema/1.0/post http://activitystrea.ms/schema/1.0/posted 0 How did we trigger scientists around the globe to uncover the low dose radiation therapy for covid 19 /slideshow/how-did-we-trigger-scientists-around-the-globe-to-uncover-the-low-dose-radiation-therapy-for-covid-19-242061037/242061037 howdidwetriggerscientistsaroundtheglobetouncoverthelowdoseradiationtherapyforcovid-19-210130191452
Any attempt to inactivate a virus exerts strong selective pressure on the virus. Given this consideration, antiviral drugs can exert strong selective pressure on SARS-COV-2. In March 2020, we proposed the concept of Low Dose Radiation Therapy (LDRT) for COVID-19 associated pneumonia. This treatment was a 100% "selective pressure-free" therapeutic approach. After our paper, tens of papers published on this issue, and now LDRT for COVID-19 is receiving rapidly increasing global attention.]]>
Any attempt to inactivate a virus exerts strong selective pressure on the virus. Given this consideration, antiviral drugs can exert strong selective pressure on SARS-COV-2. In March 2020, we proposed the concept of Low Dose Radiation Therapy (LDRT) for COVID-19 associated pneumonia. This treatment was a 100% "selective pressure-free" therapeutic approach. After our paper, tens of papers published on this issue, and now LDRT for COVID-19 is receiving rapidly increasing global attention.]]> Sat, 30 Jan 2021 19:14:51 GMT /slideshow/how-did-we-trigger-scientists-around-the-globe-to-uncover-the-low-dose-radiation-therapy-for-covid-19-242061037/242061037 mortazavi@slideshare.net(mortazavi) How did we trigger scientists around the globe to uncover the low dose radiation therapy for covid 19 mortazavi Any attempt to inactivate a virus exerts strong selective pressure on the virus. Given this consideration, antiviral drugs can exert strong selective pressure on SARS-COV-2. In March 2020, we proposed the concept of Low Dose Radiation Therapy (LDRT) for COVID-19 associated pneumonia. This treatment was a 100% "selective pressure-free" therapeutic approach. After our paper, tens of papers published on this issue, and now LDRT for COVID-19 is receiving rapidly increasing global attention. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/howdidwetriggerscientistsaroundtheglobetouncoverthelowdoseradiationtherapyforcovid-19-210130191452-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> Any attempt to inactivate a virus exerts strong selective pressure on the virus. Given this consideration, antiviral drugs can exert strong selective pressure on SARS-COV-2. In March 2020, we proposed the concept of Low Dose Radiation Therapy (LDRT) for COVID-19 associated pneumonia. This treatment was a 100% &quot;selective pressure-free&quot; therapeutic approach. After our paper, tens of papers published on this issue, and now LDRT for COVID-19 is receiving rapidly increasing global attention.
How did we trigger scientists around the globe to uncover the low dose radiation therapy for covid 19 from SMJ Mortazavi
]]> 109 0 https://cdn.slidesharecdn.com/ss_thumbnails/howdidwetriggerscientistsaroundtheglobetouncoverthelowdoseradiationtherapyforcovid-19-210130191452-thumbnail.jpg?width=120&height=120&fit=bounds presentation Black http://activitystrea.ms/schema/1.0/post http://activitystrea.ms/schema/1.0/posted 0 Low-dose radiation therapy (LDRT) for COVID-19 associated pneumonia /mortazavi/lowdose-radiation-therapy-ldrt-for-covid19-associated-pneumonia may312020-ldrt-200530174653
The efficiency of low dose radiation therapy as a potential treatment of pneumonia in COVID-19 patients has been addressed by many scientists from different parts of the world. For further reading please see the first report of Ghadimi-Moghadam et al. (COVID-19 Tragic Pandemic: Concerns over Unintentional Directed Accelerated Evolution of Novel Coronavirus (SARS-CoV-2) and Introducing a Modified Treatment Method for ARDS https://lnkd.in/dzXtqkc) and later reports by Canadian (Is low dose radiation therapy a potential treatment for COVID-19 pneumonia? https://lnkd.in/d7TQKcS), Spanish (Low Dose Lung Radiotherapy for COVID-19 Pneumonia. The Rationale for a Cost-Effective Anti-Inflammatory Treatment https://lnkd.in/dStMJKr), American (Low dose radiation therapy as a potential life saving treatment for COVID-19-induced acute respiratory distress syndrome (ARDS) https://lnkd.in/dnR8kyJ), German (Low-dose radiation therapy for COVID-19 pneumopathy: what is the evidence? https://lnkd.in/dWGCQBb) and French (Irradiation pulmonaire faible dose pour lorage de cytokines du COVID-19 : pourquoi pas ? https://lnkd.in/dsW65ew) scientists. ]]>
The efficiency of low dose radiation therapy as a potential treatment of pneumonia in COVID-19 patients has been addressed by many scientists from different parts of the world. For further reading please see the first report of Ghadimi-Moghadam et al. (COVID-19 Tragic Pandemic: Concerns over Unintentional Directed Accelerated Evolution of Novel Coronavirus (SARS-CoV-2) and Introducing a Modified Treatment Method for ARDS https://lnkd.in/dzXtqkc) and later reports by Canadian (Is low dose radiation therapy a potential treatment for COVID-19 pneumonia? https://lnkd.in/d7TQKcS), Spanish (Low Dose Lung Radiotherapy for COVID-19 Pneumonia. The Rationale for a Cost-Effective Anti-Inflammatory Treatment https://lnkd.in/dStMJKr), American (Low dose radiation therapy as a potential life saving treatment for COVID-19-induced acute respiratory distress syndrome (ARDS) https://lnkd.in/dnR8kyJ), German (Low-dose radiation therapy for COVID-19 pneumopathy: what is the evidence? https://lnkd.in/dWGCQBb) and French (Irradiation pulmonaire faible dose pour lorage de cytokines du COVID-19 : pourquoi pas ? https://lnkd.in/dsW65ew) scientists. ]]> Sat, 30 May 2020 17:46:53 GMT /mortazavi/lowdose-radiation-therapy-ldrt-for-covid19-associated-pneumonia mortazavi@slideshare.net(mortazavi) Low-dose radiation therapy (LDRT) for COVID-19 associated pneumonia mortazavi The efficiency of low dose radiation therapy as a potential treatment of pneumonia in COVID-19 patients has been addressed by many scientists from different parts of the world. For further reading please see the first report of Ghadimi-Moghadam et al. (COVID-19 Tragic Pandemic: Concerns over Unintentional Directed Accelerated Evolution of Novel Coronavirus (SARS-CoV-2) and Introducing a Modified Treatment Method for ARDS https://lnkd.in/dzXtqkc) and later reports by Canadian (Is low dose radiation therapy a potential treatment for COVID-19 pneumonia? https://lnkd.in/d7TQKcS), Spanish (Low Dose Lung Radiotherapy for COVID-19 Pneumonia. The Rationale for a Cost-Effective Anti-Inflammatory Treatment https://lnkd.in/dStMJKr), American (Low dose radiation therapy as a potential life saving treatment for COVID-19-induced acute respiratory distress syndrome (ARDS) https://lnkd.in/dnR8kyJ), German (Low-dose radiation therapy for COVID-19 pneumopathy: what is the evidence? https://lnkd.in/dWGCQBb) and French (Irradiation pulmonaire faible dose pour lorage de cytokines du COVID-19 : pourquoi pas ? https://lnkd.in/dsW65ew) scientists. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/may312020-ldrt-200530174653-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> The efficiency of low dose radiation therapy as a potential treatment of pneumonia in COVID-19 patients has been addressed by many scientists from different parts of the world. For further reading please see the first report of Ghadimi-Moghadam et al. (COVID-19 Tragic Pandemic: Concerns over Unintentional Directed Accelerated Evolution of Novel Coronavirus (SARS-CoV-2) and Introducing a Modified Treatment Method for ARDS https://lnkd.in/dzXtqkc) and later reports by Canadian (Is low dose radiation therapy a potential treatment for COVID-19 pneumonia? https://lnkd.in/d7TQKcS), Spanish (Low Dose Lung Radiotherapy for COVID-19 Pneumonia. The Rationale for a Cost-Effective Anti-Inflammatory Treatment https://lnkd.in/dStMJKr), American (Low dose radiation therapy as a potential life saving treatment for COVID-19-induced acute respiratory distress syndrome (ARDS) https://lnkd.in/dnR8kyJ), German (Low-dose radiation therapy for COVID-19 pneumopathy: what is the evidence? https://lnkd.in/dWGCQBb) and French (Irradiation pulmonaire faible dose pour lorage de cytokines du COVID-19 : pourquoi pas ? https://lnkd.in/dsW65ew) scientists.
Low-dose radiation therapy (LDRT) for COVID-19 associated pneumonia from SMJ Mortazavi
]]> 152 0 https://cdn.slidesharecdn.com/ss_thumbnails/may312020-ldrt-200530174653-thumbnail.jpg?width=120&height=120&fit=bounds presentation Black http://activitystrea.ms/schema/1.0/post http://activitystrea.ms/schema/1.0/posted 0 The Challenges of J-shaped Dose Response Models for Ionizing and Non-ionizing Radiations: 鐃The Roots of Controversy /slideshow/the-challenges-of-jshaped-dose-response-models-for-ionizing-and-nonionizing-radiations-the-roots-of-controversy/207816330 smjminvitedtalk-191219165129
An accumulating body of evidence indicates that living organisms exposed to specific windows of doses/dose rates of both ionizing and non-ionizing radiation demonstrate J-shaped dose response curves. Evaluation of these dose-response curves is of great importance in radiation biology as well as radiation protection. Studies conducted by my colleagues and I show that the general patterns of induction of phenomena such as adaptive response are similar for ionizing and non-ionizing radiations. Given this consideration, we have previously reported that the so called dose window theory that is well discussed for adaptive responses induced by ionizing radiation, is valid for non-ionizing radiation. Recently, after reviewing the current literature, we provided data indicating that in a similar pattern with ionizing radiation, the carcinogenesis of non-ionizing radiofrequency electromagnetic fields (RF-EMF) may have a nonlinear dose-response relationship. In particular, we introduced data that support the validity of a J-shaped dose-response relationship. Considering the pattern of J-shaped dose response models, ignoring the key issue of the exposure level (low levels vs. high-level exposures) can be introduced as a main root of current controversial reports regarding the carcinogenesis of RF-EMF. In this light, some studies show an association between mobile phone use and brain tumors, especially in people who used their mobile phones for long durations (e.g. 10 years). In summary, better understanding of the J-shaped dose response models for both ionizing and non-ionizing radiations can shed some light on the dark corners of current controversies about the adverse health effects of low-level exposures.]]>
An accumulating body of evidence indicates that living organisms exposed to specific windows of doses/dose rates of both ionizing and non-ionizing radiation demonstrate J-shaped dose response curves. Evaluation of these dose-response curves is of great importance in radiation biology as well as radiation protection. Studies conducted by my colleagues and I show that the general patterns of induction of phenomena such as adaptive response are similar for ionizing and non-ionizing radiations. Given this consideration, we have previously reported that the so called dose window theory that is well discussed for adaptive responses induced by ionizing radiation, is valid for non-ionizing radiation. Recently, after reviewing the current literature, we provided data indicating that in a similar pattern with ionizing radiation, the carcinogenesis of non-ionizing radiofrequency electromagnetic fields (RF-EMF) may have a nonlinear dose-response relationship. In particular, we introduced data that support the validity of a J-shaped dose-response relationship. Considering the pattern of J-shaped dose response models, ignoring the key issue of the exposure level (low levels vs. high-level exposures) can be introduced as a main root of current controversial reports regarding the carcinogenesis of RF-EMF. In this light, some studies show an association between mobile phone use and brain tumors, especially in people who used their mobile phones for long durations (e.g. 10 years). In summary, better understanding of the J-shaped dose response models for both ionizing and non-ionizing radiations can shed some light on the dark corners of current controversies about the adverse health effects of low-level exposures.]]> Thu, 19 Dec 2019 16:51:29 GMT /slideshow/the-challenges-of-jshaped-dose-response-models-for-ionizing-and-nonionizing-radiations-the-roots-of-controversy/207816330 mortazavi@slideshare.net(mortazavi) The Challenges of J-shaped Dose Response Models for Ionizing and Non-ionizing Radiations: 鐃The Roots of Controversy mortazavi An accumulating body of evidence indicates that living organisms exposed to specific windows of doses/dose rates of both ionizing and non-ionizing radiation demonstrate J-shaped dose response curves. Evaluation of these dose-response curves is of great importance in radiation biology as well as radiation protection. Studies conducted by my colleagues and I show that the general patterns of induction of phenomena such as adaptive response are similar for ionizing and non-ionizing radiations. Given this consideration, we have previously reported that the so called dose window theory that is well discussed for adaptive responses induced by ionizing radiation, is valid for non-ionizing radiation. Recently, after reviewing the current literature, we provided data indicating that in a similar pattern with ionizing radiation, the carcinogenesis of non-ionizing radiofrequency electromagnetic fields (RF-EMF) may have a nonlinear dose-response relationship. In particular, we introduced data that support the validity of a J-shaped dose-response relationship. Considering the pattern of J-shaped dose response models, ignoring the key issue of the exposure level (low levels vs. high-level exposures) can be introduced as a main root of current controversial reports regarding the carcinogenesis of RF-EMF. In this light, some studies show an association between mobile phone use and brain tumors, especially in people who used their mobile phones for long durations (e.g. 10 years). In summary, better understanding of the J-shaped dose response models for both ionizing and non-ionizing radiations can shed some light on the dark corners of current controversies about the adverse health effects of low-level exposures. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/smjminvitedtalk-191219165129-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> An accumulating body of evidence indicates that living organisms exposed to specific windows of doses/dose rates of both ionizing and non-ionizing radiation demonstrate J-shaped dose response curves. Evaluation of these dose-response curves is of great importance in radiation biology as well as radiation protection. Studies conducted by my colleagues and I show that the general patterns of induction of phenomena such as adaptive response are similar for ionizing and non-ionizing radiations. Given this consideration, we have previously reported that the so called dose window theory that is well discussed for adaptive responses induced by ionizing radiation, is valid for non-ionizing radiation. Recently, after reviewing the current literature, we provided data indicating that in a similar pattern with ionizing radiation, the carcinogenesis of non-ionizing radiofrequency electromagnetic fields (RF-EMF) may have a nonlinear dose-response relationship. In particular, we introduced data that support the validity of a J-shaped dose-response relationship. Considering the pattern of J-shaped dose response models, ignoring the key issue of the exposure level (low levels vs. high-level exposures) can be introduced as a main root of current controversial reports regarding the carcinogenesis of RF-EMF. In this light, some studies show an association between mobile phone use and brain tumors, especially in people who used their mobile phones for long durations (e.g. 10 years). In summary, better understanding of the J-shaped dose response models for both ionizing and non-ionizing radiations can shed some light on the dark corners of current controversies about the adverse health effects of low-level exposures.
The Challenges of J-shaped Dose Response Models for Ionizing and Non-ionizing Radiations: The Roots of Controversy from SMJ Mortazavi
]]> 113 2 https://cdn.slidesharecdn.com/ss_thumbnails/smjminvitedtalk-191219165129-thumbnail.jpg?width=120&height=120&fit=bounds presentation Black http://activitystrea.ms/schema/1.0/post http://activitystrea.ms/schema/1.0/posted 0 Lecture at University of Wisconsin, Madison - April 2, 2018 /slideshow/lecture-at-university-of-wisconsin-madison-april-2-2018-93124724/93124724 lectureatuniversityofwisconsinmadison-april22018-180406210146
Large SPEs, especially when the shielding is inadequate, not only increase the risk of cancer, but also the possibility of occurrence of acute radiation syndrome (ARS). As physical shielding alone cannot solve current space radiation problems, in 2003 we introduced the adaptive response as an efficient model of biological protection. The development of this model is discussed in our recent publications. A recently published paper, authored by 30 scientists from countries such as US, UK, Russia, and Belgium has confirmed the need for selection of astronauts based on their adaptive response (this paper cites our reports on how AR helps choosing the astronauts for a deep space mission). Moreover, A NASA report published in 2016 has cited our early report on the importance of radioadaptive response in space missions and states that cells can be expected to be exposed to multiple hits of protons before being traversed by an HZE particle. However, substantial evidence showing that SPEs are a real concern, indicate that our proposed model is more applicable and evidence-based. Regarding the risk of infection, change of the virulence (ability to cause disease) of microorganisms and astronauts dysregulated immune system, significantly increases the infection risk in deep space missions. ]]>
Large SPEs, especially when the shielding is inadequate, not only increase the risk of cancer, but also the possibility of occurrence of acute radiation syndrome (ARS). As physical shielding alone cannot solve current space radiation problems, in 2003 we introduced the adaptive response as an efficient model of biological protection. The development of this model is discussed in our recent publications. A recently published paper, authored by 30 scientists from countries such as US, UK, Russia, and Belgium has confirmed the need for selection of astronauts based on their adaptive response (this paper cites our reports on how AR helps choosing the astronauts for a deep space mission). Moreover, A NASA report published in 2016 has cited our early report on the importance of radioadaptive response in space missions and states that cells can be expected to be exposed to multiple hits of protons before being traversed by an HZE particle. However, substantial evidence showing that SPEs are a real concern, indicate that our proposed model is more applicable and evidence-based. Regarding the risk of infection, change of the virulence (ability to cause disease) of microorganisms and astronauts dysregulated immune system, significantly increases the infection risk in deep space missions. ]]> Fri, 06 Apr 2018 21:01:45 GMT /slideshow/lecture-at-university-of-wisconsin-madison-april-2-2018-93124724/93124724 mortazavi@slideshare.net(mortazavi) Lecture at University of Wisconsin, Madison - April 2, 2018 mortazavi Large SPEs, especially when the shielding is inadequate, not only increase the risk of cancer, but also the possibility of occurrence of acute radiation syndrome (ARS). As physical shielding alone cannot solve current space radiation problems, in 2003 we introduced the adaptive response as an efficient model of biological protection. The development of this model is discussed in our recent publications. A recently published paper, authored by 30 scientists from countries such as US, UK, Russia, and Belgium has confirmed the need for selection of astronauts based on their adaptive response (this paper cites our reports on how AR helps choosing the astronauts for a deep space mission). Moreover, A NASA report published in 2016 has cited our early report on the importance of radioadaptive response in space missions and states that cells can be expected to be exposed to multiple hits of protons before being traversed by an HZE particle. However, substantial evidence showing that SPEs are a real concern, indicate that our proposed model is more applicable and evidence-based. Regarding the risk of infection, change of the virulence (ability to cause disease) of microorganisms and astronauts dysregulated immune system, significantly increases the infection risk in deep space missions. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/lectureatuniversityofwisconsinmadison-april22018-180406210146-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> Large SPEs, especially when the shielding is inadequate, not only increase the risk of cancer, but also the possibility of occurrence of acute radiation syndrome (ARS). As physical shielding alone cannot solve current space radiation problems, in 2003 we introduced the adaptive response as an efficient model of biological protection. The development of this model is discussed in our recent publications. A recently published paper, authored by 30 scientists from countries such as US, UK, Russia, and Belgium has confirmed the need for selection of astronauts based on their adaptive response (this paper cites our reports on how AR helps choosing the astronauts for a deep space mission). Moreover, A NASA report published in 2016 has cited our early report on the importance of radioadaptive response in space missions and states that cells can be expected to be exposed to multiple hits of protons before being traversed by an HZE particle. However, substantial evidence showing that SPEs are a real concern, indicate that our proposed model is more applicable and evidence-based. Regarding the risk of infection, change of the virulence (ability to cause disease) of microorganisms and astronauts dysregulated immune system, significantly increases the infection risk in deep space missions.
Lecture at University of Wisconsin, Madison - April 2, 2018 from SMJ Mortazavi
]]> 124 8 https://cdn.slidesharecdn.com/ss_thumbnails/lectureatuniversityofwisconsinmadison-april22018-180406210146-thumbnail.jpg?width=120&height=120&fit=bounds presentation Black http://activitystrea.ms/schema/1.0/post http://activitystrea.ms/schema/1.0/posted 0 Strategies for reducing the risk of radiation for astronauts in space missions to mars and beyond /slideshow/strategies-for-reducing-the-risk-of-radiation-for-astronauts-in-space-missions-to-mars-and-beyond/79225691 strategiesforreducingtheriskofradiationforastronautsinspacemissionstomarsandbeyond-170828190539
Exposure to high levels of space radiation and microgravity are two important concerns which need to be addressed before any long-term manned space mission. There are also reports showing that microgravity, through a synergistic effect, increases the radiation susceptibility of living organisms. Other researchers as well as our team have conducted some experiments on design and fabrication of appropriate radiation shields for spacecrafts. However, due to some cardinal barriers such as weight limitations and extreme inadequacy of current physical shields during extravehicular activity, we strongly believe that the physical shielding alone cannot solve the problem of potential exposure to high levels of radiation in a long-term space mission. Therefore, over the past several years, we focused on two solutions; radioadaptive response and other biological-based radiation protection methods. Adaptive response, that is the increased radioresistance in cells or living organisms pre-exposed to a low adapting dose and then exposed to a high challenging dose, was firstly proposed by our team in 2003 as an effective method. This novel idea later formed the basis of many space radiation biology projects around the world. Furthermore, conventional radioprotectors cannot efficiently be used in space due to limitations such as their considerable toxicity and the very narrow time window for their effective use (radioprotectors should be used before or at the time of exposure, while astronauts cannot estimate their doses before a solar particle event). Therefore, we focused on introducing natural radiation mitigators which could be efficiently used several hours after exposure (e.g. when a solar particle event subsides and astronauts are able to estimate their doses). In these experiments, radiation mitigators were introduced by our team which could be used even 24 hours after exposure to high levels of radiation caused by unpredictable sources such as SPEs. Finally, some of our recent experiments were aimed at finding methods which could lead to boosting the immune system of astronauts during long-term missions. We investigated the effect of RF-EMFs-induced adaptive responses on immune system modulation in a mouse model of hindlimb unloading (HU). Hindlimb unloading rodent model is widely accepted by the scientific community as the model of choice for simulating spaceflight. In this study, serum levels of T helper cytokines were determined in HU mice, RF-EMF treated mice and HU mice pre-exposed to RF-EMF compared to those of untreated controls. The findings of this study will be published soon. ]]>
Exposure to high levels of space radiation and microgravity are two important concerns which need to be addressed before any long-term manned space mission. There are also reports showing that microgravity, through a synergistic effect, increases the radiation susceptibility of living organisms. Other researchers as well as our team have conducted some experiments on design and fabrication of appropriate radiation shields for spacecrafts. However, due to some cardinal barriers such as weight limitations and extreme inadequacy of current physical shields during extravehicular activity, we strongly believe that the physical shielding alone cannot solve the problem of potential exposure to high levels of radiation in a long-term space mission. Therefore, over the past several years, we focused on two solutions; radioadaptive response and other biological-based radiation protection methods. Adaptive response, that is the increased radioresistance in cells or living organisms pre-exposed to a low adapting dose and then exposed to a high challenging dose, was firstly proposed by our team in 2003 as an effective method. This novel idea later formed the basis of many space radiation biology projects around the world. Furthermore, conventional radioprotectors cannot efficiently be used in space due to limitations such as their considerable toxicity and the very narrow time window for their effective use (radioprotectors should be used before or at the time of exposure, while astronauts cannot estimate their doses before a solar particle event). Therefore, we focused on introducing natural radiation mitigators which could be efficiently used several hours after exposure (e.g. when a solar particle event subsides and astronauts are able to estimate their doses). In these experiments, radiation mitigators were introduced by our team which could be used even 24 hours after exposure to high levels of radiation caused by unpredictable sources such as SPEs. Finally, some of our recent experiments were aimed at finding methods which could lead to boosting the immune system of astronauts during long-term missions. We investigated the effect of RF-EMFs-induced adaptive responses on immune system modulation in a mouse model of hindlimb unloading (HU). Hindlimb unloading rodent model is widely accepted by the scientific community as the model of choice for simulating spaceflight. In this study, serum levels of T helper cytokines were determined in HU mice, RF-EMF treated mice and HU mice pre-exposed to RF-EMF compared to those of untreated controls. The findings of this study will be published soon. ]]> Mon, 28 Aug 2017 19:05:39 GMT /slideshow/strategies-for-reducing-the-risk-of-radiation-for-astronauts-in-space-missions-to-mars-and-beyond/79225691 mortazavi@slideshare.net(mortazavi) Strategies for reducing the risk of radiation for astronauts in space missions to mars and beyond mortazavi Exposure to high levels of space radiation and microgravity are two important concerns which need to be addressed before any long-term manned space mission. There are also reports showing that microgravity, through a synergistic effect, increases the radiation susceptibility of living organisms. Other researchers as well as our team have conducted some experiments on design and fabrication of appropriate radiation shields for spacecrafts. However, due to some cardinal barriers such as weight limitations and extreme inadequacy of current physical shields during extravehicular activity, we strongly believe that the physical shielding alone cannot solve the problem of potential exposure to high levels of radiation in a long-term space mission. Therefore, over the past several years, we focused on two solutions; radioadaptive response and other biological-based radiation protection methods. Adaptive response, that is the increased radioresistance in cells or living organisms pre-exposed to a low adapting dose and then exposed to a high challenging dose, was firstly proposed by our team in 2003 as an effective method. This novel idea later formed the basis of many space radiation biology projects around the world. Furthermore, conventional radioprotectors cannot efficiently be used in space due to limitations such as their considerable toxicity and the very narrow time window for their effective use (radioprotectors should be used before or at the time of exposure, while astronauts cannot estimate their doses before a solar particle event). Therefore, we focused on introducing natural radiation mitigators which could be efficiently used several hours after exposure (e.g. when a solar particle event subsides and astronauts are able to estimate their doses). In these experiments, radiation mitigators were introduced by our team which could be used even 24 hours after exposure to high levels of radiation caused by unpredictable sources such as SPEs. Finally, some of our recent experiments were aimed at finding methods which could lead to boosting the immune system of astronauts during long-term missions. We investigated the effect of RF-EMFs-induced adaptive responses on immune system modulation in a mouse model of hindlimb unloading (HU). Hindlimb unloading rodent model is widely accepted by the scientific community as the model of choice for simulating spaceflight. In this study, serum levels of T helper cytokines were determined in HU mice, RF-EMF treated mice and HU mice pre-exposed to RF-EMF compared to those of untreated controls. The findings of this study will be published soon. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/strategiesforreducingtheriskofradiationforastronautsinspacemissionstomarsandbeyond-170828190539-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> Exposure to high levels of space radiation and microgravity are two important concerns which need to be addressed before any long-term manned space mission. There are also reports showing that microgravity, through a synergistic effect, increases the radiation susceptibility of living organisms. Other researchers as well as our team have conducted some experiments on design and fabrication of appropriate radiation shields for spacecrafts. However, due to some cardinal barriers such as weight limitations and extreme inadequacy of current physical shields during extravehicular activity, we strongly believe that the physical shielding alone cannot solve the problem of potential exposure to high levels of radiation in a long-term space mission. Therefore, over the past several years, we focused on two solutions; radioadaptive response and other biological-based radiation protection methods. Adaptive response, that is the increased radioresistance in cells or living organisms pre-exposed to a low adapting dose and then exposed to a high challenging dose, was firstly proposed by our team in 2003 as an effective method. This novel idea later formed the basis of many space radiation biology projects around the world. Furthermore, conventional radioprotectors cannot efficiently be used in space due to limitations such as their considerable toxicity and the very narrow time window for their effective use (radioprotectors should be used before or at the time of exposure, while astronauts cannot estimate their doses before a solar particle event). Therefore, we focused on introducing natural radiation mitigators which could be efficiently used several hours after exposure (e.g. when a solar particle event subsides and astronauts are able to estimate their doses). In these experiments, radiation mitigators were introduced by our team which could be used even 24 hours after exposure to high levels of radiation caused by unpredictable sources such as SPEs. Finally, some of our recent experiments were aimed at finding methods which could lead to boosting the immune system of astronauts during long-term missions. We investigated the effect of RF-EMFs-induced adaptive responses on immune system modulation in a mouse model of hindlimb unloading (HU). Hindlimb unloading rodent model is widely accepted by the scientific community as the model of choice for simulating spaceflight. In this study, serum levels of T helper cytokines were determined in HU mice, RF-EMF treated mice and HU mice pre-exposed to RF-EMF compared to those of untreated controls. The findings of this study will be published soon.
Strategies for reducing the risk of radiation for astronauts in space missions to mars and beyond from SMJ Mortazavi
]]> 627 9 https://cdn.slidesharecdn.com/ss_thumbnails/strategiesforreducingtheriskofradiationforastronautsinspacemissionstomarsandbeyond-170828190539-thumbnail.jpg?width=120&height=120&fit=bounds presentation Black http://activitystrea.ms/schema/1.0/post http://activitystrea.ms/schema/1.0/posted 0 How does biological protection help astronauts tolerate high levels of radiation /slideshow/how-does-biological-protection-help-astronauts-tolerate-high-levels-of-radiation-75969061/75969061 howdoesbiologicalprotectionhelpastronautstoleratehighlevelsofradiation-170514233439
Abstract: Exposure to high levels of space radiation and microgravity are two important concerns which need to be addressed before any long-term manned space mission. There are also reports showing that microgravity, through a synergistic effect, increases the radiation susceptibility of living organisms. Other researchers as well as our team have conducted some experiments on design and fabrication of appropriate radiation shields for spacecrafts. However, due to some cardinal barriers such as weight limitations and extreme inadequacy of current physical shields during extravehicular activity, we strongly believe that the physical shielding alone cannot solve the problem of potential exposure to high levels of radiation in a long-term space mission. Therefore, over the past several years, we focused on two solutions; radioadaptive response and other biological-based radiation protection methods. Adaptive response, that is the increased radioresistance in cells or living organisms pre-exposed to a low adapting dose and then exposed to a high challenging dose, was firstly proposed by our team in 2003 as an effective method. This novel idea later formed the basis of many space radiation biology projects around the world. Furthermore, conventional radioprotectors cannot efficiently be used in space due to limitations such as their considerable toxicity and the very narrow time window for their effective use (radioprotectors should be used before or at the time of exposure, while astronauts cannot estimate their doses before a solar particle event). Therefore, we focused on introducing natural radiation mitigators which could be efficiently used several hours after exposure (e.g. when a solar particle event subsides and astronauts are able to estimate their doses). In these experiments, radiation mitigators were introduced by our team which could be used even 24 hours after exposure to high levels of radiation caused by unpredictable sources such as SPEs. Finally, some of our recent experiments were aimed at finding methods which could lead to boosting the immune system of astronauts during long-term missions. We investigated the effect of RF-EMFs-induced adaptive responses on immune system modulation in a mouse model of hindlimb unloading (HU). Hindlimb unloading rodent model is widely accepted by the scientific community as the model of choice for simulating spaceflight. In this study, serum levels of T helper cytokines were determined in HU mice, RF-EMF treated mice and HU mice pre-exposed to RF-EMF compared to those of untreated controls. The findings of this study will be published soon. ]]>
Abstract: Exposure to high levels of space radiation and microgravity are two important concerns which need to be addressed before any long-term manned space mission. There are also reports showing that microgravity, through a synergistic effect, increases the radiation susceptibility of living organisms. Other researchers as well as our team have conducted some experiments on design and fabrication of appropriate radiation shields for spacecrafts. However, due to some cardinal barriers such as weight limitations and extreme inadequacy of current physical shields during extravehicular activity, we strongly believe that the physical shielding alone cannot solve the problem of potential exposure to high levels of radiation in a long-term space mission. Therefore, over the past several years, we focused on two solutions; radioadaptive response and other biological-based radiation protection methods. Adaptive response, that is the increased radioresistance in cells or living organisms pre-exposed to a low adapting dose and then exposed to a high challenging dose, was firstly proposed by our team in 2003 as an effective method. This novel idea later formed the basis of many space radiation biology projects around the world. Furthermore, conventional radioprotectors cannot efficiently be used in space due to limitations such as their considerable toxicity and the very narrow time window for their effective use (radioprotectors should be used before or at the time of exposure, while astronauts cannot estimate their doses before a solar particle event). Therefore, we focused on introducing natural radiation mitigators which could be efficiently used several hours after exposure (e.g. when a solar particle event subsides and astronauts are able to estimate their doses). In these experiments, radiation mitigators were introduced by our team which could be used even 24 hours after exposure to high levels of radiation caused by unpredictable sources such as SPEs. Finally, some of our recent experiments were aimed at finding methods which could lead to boosting the immune system of astronauts during long-term missions. We investigated the effect of RF-EMFs-induced adaptive responses on immune system modulation in a mouse model of hindlimb unloading (HU). Hindlimb unloading rodent model is widely accepted by the scientific community as the model of choice for simulating spaceflight. In this study, serum levels of T helper cytokines were determined in HU mice, RF-EMF treated mice and HU mice pre-exposed to RF-EMF compared to those of untreated controls. The findings of this study will be published soon. ]]> Sun, 14 May 2017 23:34:38 GMT /slideshow/how-does-biological-protection-help-astronauts-tolerate-high-levels-of-radiation-75969061/75969061 mortazavi@slideshare.net(mortazavi) How does biological protection help astronauts tolerate high levels of radiation mortazavi Abstract: Exposure to high levels of space radiation and microgravity are two important concerns which need to be addressed before any long-term manned space mission. There are also reports showing that microgravity, through a synergistic effect, increases the radiation susceptibility of living organisms. Other researchers as well as our team have conducted some experiments on design and fabrication of appropriate radiation shields for spacecrafts. However, due to some cardinal barriers such as weight limitations and extreme inadequacy of current physical shields during extravehicular activity, we strongly believe that the physical shielding alone cannot solve the problem of potential exposure to high levels of radiation in a long-term space mission. Therefore, over the past several years, we focused on two solutions; radioadaptive response and other biological-based radiation protection methods. Adaptive response, that is the increased radioresistance in cells or living organisms pre-exposed to a low adapting dose and then exposed to a high challenging dose, was firstly proposed by our team in 2003 as an effective method. This novel idea later formed the basis of many space radiation biology projects around the world. Furthermore, conventional radioprotectors cannot efficiently be used in space due to limitations such as their considerable toxicity and the very narrow time window for their effective use (radioprotectors should be used before or at the time of exposure, while astronauts cannot estimate their doses before a solar particle event). Therefore, we focused on introducing natural radiation mitigators which could be efficiently used several hours after exposure (e.g. when a solar particle event subsides and astronauts are able to estimate their doses). In these experiments, radiation mitigators were introduced by our team which could be used even 24 hours after exposure to high levels of radiation caused by unpredictable sources such as SPEs. Finally, some of our recent experiments were aimed at finding methods which could lead to boosting the immune system of astronauts during long-term missions. We investigated the effect of RF-EMFs-induced adaptive responses on immune system modulation in a mouse model of hindlimb unloading (HU). Hindlimb unloading rodent model is widely accepted by the scientific community as the model of choice for simulating spaceflight. In this study, serum levels of T helper cytokines were determined in HU mice, RF-EMF treated mice and HU mice pre-exposed to RF-EMF compared to those of untreated controls. The findings of this study will be published soon. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/howdoesbiologicalprotectionhelpastronautstoleratehighlevelsofradiation-170514233439-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> Abstract: Exposure to high levels of space radiation and microgravity are two important concerns which need to be addressed before any long-term manned space mission. There are also reports showing that microgravity, through a synergistic effect, increases the radiation susceptibility of living organisms. Other researchers as well as our team have conducted some experiments on design and fabrication of appropriate radiation shields for spacecrafts. However, due to some cardinal barriers such as weight limitations and extreme inadequacy of current physical shields during extravehicular activity, we strongly believe that the physical shielding alone cannot solve the problem of potential exposure to high levels of radiation in a long-term space mission. Therefore, over the past several years, we focused on two solutions; radioadaptive response and other biological-based radiation protection methods. Adaptive response, that is the increased radioresistance in cells or living organisms pre-exposed to a low adapting dose and then exposed to a high challenging dose, was firstly proposed by our team in 2003 as an effective method. This novel idea later formed the basis of many space radiation biology projects around the world. Furthermore, conventional radioprotectors cannot efficiently be used in space due to limitations such as their considerable toxicity and the very narrow time window for their effective use (radioprotectors should be used before or at the time of exposure, while astronauts cannot estimate their doses before a solar particle event). Therefore, we focused on introducing natural radiation mitigators which could be efficiently used several hours after exposure (e.g. when a solar particle event subsides and astronauts are able to estimate their doses). In these experiments, radiation mitigators were introduced by our team which could be used even 24 hours after exposure to high levels of radiation caused by unpredictable sources such as SPEs. Finally, some of our recent experiments were aimed at finding methods which could lead to boosting the immune system of astronauts during long-term missions. We investigated the effect of RF-EMFs-induced adaptive responses on immune system modulation in a mouse model of hindlimb unloading (HU). Hindlimb unloading rodent model is widely accepted by the scientific community as the model of choice for simulating spaceflight. In this study, serum levels of T helper cytokines were determined in HU mice, RF-EMF treated mice and HU mice pre-exposed to RF-EMF compared to those of untreated controls. The findings of this study will be published soon.
How does biological protection help astronauts tolerate high levels of radiation from SMJ Mortazavi
]]> 334 6 https://cdn.slidesharecdn.com/ss_thumbnails/howdoesbiologicalprotectionhelpastronautstoleratehighlevelsofradiation-170514233439-thumbnail.jpg?width=120&height=120&fit=bounds presentation Black http://activitystrea.ms/schema/1.0/post http://activitystrea.ms/schema/1.0/posted 0 https://cdn.slidesharecdn.com/profile-photo-mortazavi-48x48.jpg?cb=1668444903 Prof SMJ Mortazavi is a visiting Scientist at Fox Chase Cancer Center (FCCC), Philadelphia. He also holds the position of president of the Ionizing and Non-ionizing Radiation Protection Research Center (INIRPRC). He also serves as Professor of Medical Physics in the School of Medicine of Shiraz University of Medical Sciences (SUMS). Mortazavi has authored more than 150 papers in peer reviewed journals in the areas such as non-ionizing radiation, radiation protection, dosimetry, natural radiation, radiation hormesis, radioadaptive response and the possible role of radioadaptive response in radiation protection. He has also published papers on the future role of radioadaptation in long-term... www.foxchase.org/sm-mortazavi https://cdn.slidesharecdn.com/ss_thumbnails/mercuryreleasedfromdentalamalgamfillingsinresponsetodifferentphysicalstressors-221021051614-c057b534-thumbnail.jpg?width=320&height=320&fit=bounds slideshow/mercury-released-from-dental-amalgam-fillings-in-response-to-different-physical-stressorspptx/253740743 Mercury Released from ... https://cdn.slidesharecdn.com/ss_thumbnails/revisedupdated-low-doseradiationtherapyforcovid-19-timerevealsthetruth-220711152931-f2bdac0b-thumbnail.jpg?width=320&height=320&fit=bounds slideshow/lowdose-radiation-therapy-for-covid19-time-reveals-the-truthpptx/252160845 Low-Dose Radiation The... https://cdn.slidesharecdn.com/ss_thumbnails/timerevealsthetruth-220710052312-ade0cbbc-thumbnail.jpg?width=320&height=320&fit=bounds slideshow/time-reveals-the-truthpdf/252153194 Time reveals the truth...