際際滷shows by User: prachipandey924090 / http://www.slideshare.net/images/logo.gif 際際滷shows by User: prachipandey924090 / Wed, 20 Mar 2024 16:56:00 GMT 際際滷Share feed for 際際滷shows by User: prachipandey924090 Niosome An Non-Ionic Surfactant Vesicles.pptx /slideshow/niosome-an-nonionic-surfactant-vesiclespptx/266889926 niosomeannon-ionicsurfactantvesicles-240320165600-592c4e33
Niosomes are nanosized vesicles composed of nonionic surfactants and cholesterol that form when these compounds are dispersed in an aqueous medium. These lipid-based structures are similar to liposomes but differ in their composition, as niosomes use nonionic surfactants instead of phospholipids. The unique characteristic of niosomes lies in their ability to encapsulate both hydrophilic and hydrophobic drugs within their bilayer membrane. This feature makes them promising candidates for drug delivery systems, as they can protect the encapsulated drug from degradation, prolong its release, and enhance its bioavailability. Additionally, niosomes offer advantages such as biocompatibility, stability, and ease of preparation, making them a versatile platform for targeted drug delivery and other biomedical applications.]]>

Niosomes are nanosized vesicles composed of nonionic surfactants and cholesterol that form when these compounds are dispersed in an aqueous medium. These lipid-based structures are similar to liposomes but differ in their composition, as niosomes use nonionic surfactants instead of phospholipids. The unique characteristic of niosomes lies in their ability to encapsulate both hydrophilic and hydrophobic drugs within their bilayer membrane. This feature makes them promising candidates for drug delivery systems, as they can protect the encapsulated drug from degradation, prolong its release, and enhance its bioavailability. Additionally, niosomes offer advantages such as biocompatibility, stability, and ease of preparation, making them a versatile platform for targeted drug delivery and other biomedical applications.]]>
Wed, 20 Mar 2024 16:56:00 GMT /slideshow/niosome-an-nonionic-surfactant-vesiclespptx/266889926 prachipandey924090@slideshare.net(prachipandey924090) Niosome An Non-Ionic Surfactant Vesicles.pptx prachipandey924090 Niosomes are nanosized vesicles composed of nonionic surfactants and cholesterol that form when these compounds are dispersed in an aqueous medium. These lipid-based structures are similar to liposomes but differ in their composition, as niosomes use nonionic surfactants instead of phospholipids. The unique characteristic of niosomes lies in their ability to encapsulate both hydrophilic and hydrophobic drugs within their bilayer membrane. This feature makes them promising candidates for drug delivery systems, as they can protect the encapsulated drug from degradation, prolong its release, and enhance its bioavailability. Additionally, niosomes offer advantages such as biocompatibility, stability, and ease of preparation, making them a versatile platform for targeted drug delivery and other biomedical applications. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/niosomeannon-ionicsurfactantvesicles-240320165600-592c4e33-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> Niosomes are nanosized vesicles composed of nonionic surfactants and cholesterol that form when these compounds are dispersed in an aqueous medium. These lipid-based structures are similar to liposomes but differ in their composition, as niosomes use nonionic surfactants instead of phospholipids. The unique characteristic of niosomes lies in their ability to encapsulate both hydrophilic and hydrophobic drugs within their bilayer membrane. This feature makes them promising candidates for drug delivery systems, as they can protect the encapsulated drug from degradation, prolong its release, and enhance its bioavailability. Additionally, niosomes offer advantages such as biocompatibility, stability, and ease of preparation, making them a versatile platform for targeted drug delivery and other biomedical applications.
Niosome An Non-Ionic Surfactant Vesicles.pptx from Prachi Pandey
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Niosomes (Formulation and evaluation).pptx /slideshow/niosomes-formulation-and-evaluationpptx-1777/266599437 niosomesformulationandevaluation-240303044608-ca334496
Niosomes are a novel drug delivery system that encapsulates the medication in a vesicular system made up of non ionic surfactants. The vesicle is made up of a bilayer of non-ionic surfactants, thus the name niosomes. Niosomes are extremely small and microscopic (on a nanometric scale). Despite having a similar structure to liposomes, they have several advantages over them. Niosomesare biocompatible, nonimmunogenic, and biodegradable in nature and exhibit flexibility in their structured characterization Based on the vesicle size, niosomes can be divided into three groups. Small unilamellar vesicles (SUV, size=0.025-0.05 亮m), Multilamellar vesicles (MLV, size=>0.05 亮m), and Large unilamellar vesicles (LUV, size=>0.10 亮m). In the formulation of niosomes, the selection of surfactants is based on hydrophilic-lipophilic balance (HLB) value. HLB values between 4 and 8 recommended for the facile formation of niosomes and surfactants with an HLB value of more than 8 are required to optimize cholesterol concentration. However, it has been widely observed that HLB value between 4 and 8 is highly recommended for better encapsulation efficiency, of niosomes. For example, long stearyl and short lauryl chain length increase and decrease the entrapment efficiency of niosomes, respectively. Long hydrophilic chains result in increased encapsulation of hydrophilic drugs, and long hydrophobic chains result in improved encapsulation of lipophilic drugs. Long Hydrophilic Chains and Increased Encapsulation of Hydrophilic Drugs: Surfactants with longer hydrophilic chains create larger aqueous compartments within the niosome bilayer. This provides more space for water-soluble drugs to reside, leading to higher encapsulation efficiency. Example: Span 60 (HLB 4.7) has a longer hydrophilic chain compared to Span 20 (HLB 8.6). Studies have shown that using Span 60 in niosomes resulted in significantly higher encapsulation efficiency of the hydrophilic drug gentamicin, compared to formulations using Span 20. Long Hydrophobic Chains and Improved Encapsulation of Lipophilic Drugs: Long hydrophobic chains increase the affinity of the niosome bilayer for lipid-soluble drugs. These drugs can partition and entrap themselves within the bilayer structure, leading to improved encapsulation. Example: Tween 80 (HLB 15) has a longer hydrophobic chain compared to Tween 20 (HLB 16.7). Niosomes prepared with Tween 80 demonstrated superior encapsulation of the lipophilic drug curcumin compared to those made with Tween 20. Pegylation is a process where polyethylene glycol (PEG), a biocompatible and hydrophilic polymer, is attached to the surface of niosomes. This modification offers several advantages for drug delivery: Benefits of Pegylation: Increased Stability:PEG creates a steric barrier,preventing proteins and other molecules in the blood from adhering to the niosome surface.This reduces aggregation and opsonization (recognition by immune cells).]]>

Niosomes are a novel drug delivery system that encapsulates the medication in a vesicular system made up of non ionic surfactants. The vesicle is made up of a bilayer of non-ionic surfactants, thus the name niosomes. Niosomes are extremely small and microscopic (on a nanometric scale). Despite having a similar structure to liposomes, they have several advantages over them. Niosomesare biocompatible, nonimmunogenic, and biodegradable in nature and exhibit flexibility in their structured characterization Based on the vesicle size, niosomes can be divided into three groups. Small unilamellar vesicles (SUV, size=0.025-0.05 亮m), Multilamellar vesicles (MLV, size=>0.05 亮m), and Large unilamellar vesicles (LUV, size=>0.10 亮m). In the formulation of niosomes, the selection of surfactants is based on hydrophilic-lipophilic balance (HLB) value. HLB values between 4 and 8 recommended for the facile formation of niosomes and surfactants with an HLB value of more than 8 are required to optimize cholesterol concentration. However, it has been widely observed that HLB value between 4 and 8 is highly recommended for better encapsulation efficiency, of niosomes. For example, long stearyl and short lauryl chain length increase and decrease the entrapment efficiency of niosomes, respectively. Long hydrophilic chains result in increased encapsulation of hydrophilic drugs, and long hydrophobic chains result in improved encapsulation of lipophilic drugs. Long Hydrophilic Chains and Increased Encapsulation of Hydrophilic Drugs: Surfactants with longer hydrophilic chains create larger aqueous compartments within the niosome bilayer. This provides more space for water-soluble drugs to reside, leading to higher encapsulation efficiency. Example: Span 60 (HLB 4.7) has a longer hydrophilic chain compared to Span 20 (HLB 8.6). Studies have shown that using Span 60 in niosomes resulted in significantly higher encapsulation efficiency of the hydrophilic drug gentamicin, compared to formulations using Span 20. Long Hydrophobic Chains and Improved Encapsulation of Lipophilic Drugs: Long hydrophobic chains increase the affinity of the niosome bilayer for lipid-soluble drugs. These drugs can partition and entrap themselves within the bilayer structure, leading to improved encapsulation. Example: Tween 80 (HLB 15) has a longer hydrophobic chain compared to Tween 20 (HLB 16.7). Niosomes prepared with Tween 80 demonstrated superior encapsulation of the lipophilic drug curcumin compared to those made with Tween 20. Pegylation is a process where polyethylene glycol (PEG), a biocompatible and hydrophilic polymer, is attached to the surface of niosomes. This modification offers several advantages for drug delivery: Benefits of Pegylation: Increased Stability:PEG creates a steric barrier,preventing proteins and other molecules in the blood from adhering to the niosome surface.This reduces aggregation and opsonization (recognition by immune cells).]]>
Sun, 03 Mar 2024 04:46:08 GMT /slideshow/niosomes-formulation-and-evaluationpptx-1777/266599437 prachipandey924090@slideshare.net(prachipandey924090) Niosomes (Formulation and evaluation).pptx prachipandey924090 Niosomes are a novel drug delivery system that encapsulates the medication in a vesicular system made up of non ionic surfactants. The vesicle is made up of a bilayer of non-ionic surfactants, thus the name niosomes. Niosomes are extremely small and microscopic (on a nanometric scale). Despite having a similar structure to liposomes, they have several advantages over them. Niosomesare biocompatible, nonimmunogenic, and biodegradable in nature and exhibit flexibility in their structured characterization Based on the vesicle size, niosomes can be divided into three groups. Small unilamellar vesicles (SUV, size=0.025-0.05 亮m), Multilamellar vesicles (MLV, size=>0.05 亮m), and Large unilamellar vesicles (LUV, size=>0.10 亮m). In the formulation of niosomes, the selection of surfactants is based on hydrophilic-lipophilic balance (HLB) value. HLB values between 4 and 8 recommended for the facile formation of niosomes and surfactants with an HLB value of more than 8 are required to optimize cholesterol concentration. However, it has been widely observed that HLB value between 4 and 8 is highly recommended for better encapsulation efficiency, of niosomes. For example, long stearyl and short lauryl chain length increase and decrease the entrapment efficiency of niosomes, respectively. Long hydrophilic chains result in increased encapsulation of hydrophilic drugs, and long hydrophobic chains result in improved encapsulation of lipophilic drugs. Long Hydrophilic Chains and Increased Encapsulation of Hydrophilic Drugs: Surfactants with longer hydrophilic chains create larger aqueous compartments within the niosome bilayer. This provides more space for water-soluble drugs to reside, leading to higher encapsulation efficiency. Example: Span 60 (HLB 4.7) has a longer hydrophilic chain compared to Span 20 (HLB 8.6). Studies have shown that using Span 60 in niosomes resulted in significantly higher encapsulation efficiency of the hydrophilic drug gentamicin, compared to formulations using Span 20. Long Hydrophobic Chains and Improved Encapsulation of Lipophilic Drugs: Long hydrophobic chains increase the affinity of the niosome bilayer for lipid-soluble drugs. These drugs can partition and entrap themselves within the bilayer structure, leading to improved encapsulation. Example: Tween 80 (HLB 15) has a longer hydrophobic chain compared to Tween 20 (HLB 16.7). Niosomes prepared with Tween 80 demonstrated superior encapsulation of the lipophilic drug curcumin compared to those made with Tween 20. Pegylation is a process where polyethylene glycol (PEG), a biocompatible and hydrophilic polymer, is attached to the surface of niosomes. This modification offers several advantages for drug delivery: Benefits of Pegylation: Increased Stability:PEG creates a steric barrier,preventing proteins and other molecules in the blood from adhering to the niosome surface.This reduces aggregation and opsonization (recognition by immune cells). <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/niosomesformulationandevaluation-240303044608-ca334496-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> Niosomes are a novel drug delivery system that encapsulates the medication in a vesicular system made up of non ionic surfactants. The vesicle is made up of a bilayer of non-ionic surfactants, thus the name niosomes. Niosomes are extremely small and microscopic (on a nanometric scale). Despite having a similar structure to liposomes, they have several advantages over them. Niosomesare biocompatible, nonimmunogenic, and biodegradable in nature and exhibit flexibility in their structured characterization Based on the vesicle size, niosomes can be divided into three groups. Small unilamellar vesicles (SUV, size=0.025-0.05 亮m), Multilamellar vesicles (MLV, size=&gt;0.05 亮m), and Large unilamellar vesicles (LUV, size=&gt;0.10 亮m). In the formulation of niosomes, the selection of surfactants is based on hydrophilic-lipophilic balance (HLB) value. HLB values between 4 and 8 recommended for the facile formation of niosomes and surfactants with an HLB value of more than 8 are required to optimize cholesterol concentration. However, it has been widely observed that HLB value between 4 and 8 is highly recommended for better encapsulation efficiency, of niosomes. For example, long stearyl and short lauryl chain length increase and decrease the entrapment efficiency of niosomes, respectively. Long hydrophilic chains result in increased encapsulation of hydrophilic drugs, and long hydrophobic chains result in improved encapsulation of lipophilic drugs. Long Hydrophilic Chains and Increased Encapsulation of Hydrophilic Drugs: Surfactants with longer hydrophilic chains create larger aqueous compartments within the niosome bilayer. This provides more space for water-soluble drugs to reside, leading to higher encapsulation efficiency. Example: Span 60 (HLB 4.7) has a longer hydrophilic chain compared to Span 20 (HLB 8.6). Studies have shown that using Span 60 in niosomes resulted in significantly higher encapsulation efficiency of the hydrophilic drug gentamicin, compared to formulations using Span 20. Long Hydrophobic Chains and Improved Encapsulation of Lipophilic Drugs: Long hydrophobic chains increase the affinity of the niosome bilayer for lipid-soluble drugs. These drugs can partition and entrap themselves within the bilayer structure, leading to improved encapsulation. Example: Tween 80 (HLB 15) has a longer hydrophobic chain compared to Tween 20 (HLB 16.7). Niosomes prepared with Tween 80 demonstrated superior encapsulation of the lipophilic drug curcumin compared to those made with Tween 20. Pegylation is a process where polyethylene glycol (PEG), a biocompatible and hydrophilic polymer, is attached to the surface of niosomes. This modification offers several advantages for drug delivery: Benefits of Pegylation: Increased Stability:PEG creates a steric barrier,preventing proteins and other molecules in the blood from adhering to the niosome surface.This reduces aggregation and opsonization (recognition by immune cells).
Niosomes (Formulation and evaluation).pptx from Prachi Pandey
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ю: ююю юю ( .-); Advancement and Characteristics of Non-Ionic Surfactant Vesicle (Niosome) And Their Application For Analgesics. /slideshow/advancement-and-characteristics-of-nonionic-surfactant-vesicle-niosome-and-their-application-for-analgesics/265826799 analgesicniosomes-240126132130-40f8f338
Non-ionic surfactant vesicles, commonly referred to as niosomes, have garnered significant attention within the pharmaceutical industry due to their remarkable capacity to encapsulate both hydrophilic and hydrophobic drugs. Recent studies have demonstrated the potential of these vesicles to enhance the bioavailability of drugs, making them a promising strategy for delivering various therapeutic agents such as gene materials, protein therapeutics, and chemical pharmaceuticals. This approach offers minimal toxicity and desirable targeting effectiveness. Niosomes are substantially more stable during the preparation and storage procedure than liposomes. The desired pharmacokinetics property can be attained through the optimization of constituents or surface modifications. This novel method of distribution is also facile to establish and expand, while maintaining cost-effective manufacturing expenses. This review article elucidates the fundamentals of niosomes as non-ionic surfactant vesicles, including their structure and components, as well as various formulation methods. Additionally, the article explores the diverse applications of niosomal in the analgesics.]]>

Non-ionic surfactant vesicles, commonly referred to as niosomes, have garnered significant attention within the pharmaceutical industry due to their remarkable capacity to encapsulate both hydrophilic and hydrophobic drugs. Recent studies have demonstrated the potential of these vesicles to enhance the bioavailability of drugs, making them a promising strategy for delivering various therapeutic agents such as gene materials, protein therapeutics, and chemical pharmaceuticals. This approach offers minimal toxicity and desirable targeting effectiveness. Niosomes are substantially more stable during the preparation and storage procedure than liposomes. The desired pharmacokinetics property can be attained through the optimization of constituents or surface modifications. This novel method of distribution is also facile to establish and expand, while maintaining cost-effective manufacturing expenses. This review article elucidates the fundamentals of niosomes as non-ionic surfactant vesicles, including their structure and components, as well as various formulation methods. Additionally, the article explores the diverse applications of niosomal in the analgesics.]]>
Fri, 26 Jan 2024 13:21:29 GMT /slideshow/advancement-and-characteristics-of-nonionic-surfactant-vesicle-niosome-and-their-application-for-analgesics/265826799 prachipandey924090@slideshare.net(prachipandey924090) ю: ююю юю ( .-); Advancement and Characteristics of Non-Ionic Surfactant Vesicle (Niosome) And Their Application For Analgesics. prachipandey924090 Non-ionic surfactant vesicles, commonly referred to as niosomes, have garnered significant attention within the pharmaceutical industry due to their remarkable capacity to encapsulate both hydrophilic and hydrophobic drugs. Recent studies have demonstrated the potential of these vesicles to enhance the bioavailability of drugs, making them a promising strategy for delivering various therapeutic agents such as gene materials, protein therapeutics, and chemical pharmaceuticals. This approach offers minimal toxicity and desirable targeting effectiveness. Niosomes are substantially more stable during the preparation and storage procedure than liposomes. The desired pharmacokinetics property can be attained through the optimization of constituents or surface modifications. This novel method of distribution is also facile to establish and expand, while maintaining cost-effective manufacturing expenses. This review article elucidates the fundamentals of niosomes as non-ionic surfactant vesicles, including their structure and components, as well as various formulation methods. Additionally, the article explores the diverse applications of niosomal in the analgesics. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/analgesicniosomes-240126132130-40f8f338-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> Non-ionic surfactant vesicles, commonly referred to as niosomes, have garnered significant attention within the pharmaceutical industry due to their remarkable capacity to encapsulate both hydrophilic and hydrophobic drugs. Recent studies have demonstrated the potential of these vesicles to enhance the bioavailability of drugs, making them a promising strategy for delivering various therapeutic agents such as gene materials, protein therapeutics, and chemical pharmaceuticals. This approach offers minimal toxicity and desirable targeting effectiveness. Niosomes are substantially more stable during the preparation and storage procedure than liposomes. The desired pharmacokinetics property can be attained through the optimization of constituents or surface modifications. This novel method of distribution is also facile to establish and expand, while maintaining cost-effective manufacturing expenses. This review article elucidates the fundamentals of niosomes as non-ionic surfactant vesicles, including their structure and components, as well as various formulation methods. Additionally, the article explores the diverse applications of niosomal in the analgesics.
ь罎 罎紮茖嬢 ь茖嬢茖嬢駆錘罎錘筝: 膕駆錘茖嬢ь駆罎錘筝駆罎 駆羮茖嬢ь茖嬢駆茖 (膕蕭綉ィ 羆.羃-羆嬢羃羆嬢羆); Advancement and Characteristics of Non-Ionic Surfactant Vesicle (Niosome) And Their Application For Analgesics. from Prachi Pandey
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The Application of Response Surface Methodology (RSM) In the Computational Optimization of Sustained Release (SR) For Phenothiazine Derivative Matrix Tablet /slideshow/the-application-of-response-surface-methodology-rsm-in-the-computational-optimization-of-sustained-release-sr-for-phenothiazine-derivative-matrix-tablet/265420791 thakur35352024jpri111654-240115065550-a4de0d46
Introduction: This study explores the use of Response Surface Methodology (RSM), a statistical optimization technique, to optimize the SR properties of prochlorperazine maleate (PCM) matrix tablets. PCM is a phenothiazine derivative used for treating schizophrenia, nausea, and vomiting. Sustained-release formulations offer extended drug delivery, potentially improving patient compliance and reducing side effects. RSM helps identify optimal combinations of critical formulation factors influencing drug release, such as polymer type and concentration, filler type, and drug/polymer ratio. The study likely involves designing experiments based on chosen RSM designs (e.g., Box-Behnken) with varying factor levels. Formulate SR tablets with different factor combinations. Evaluating the drug release profiles of each tablet formulation. Analyzing data using RSM software to build mathematical models relating factors to drug release and identifying optimal factor combinations that maximize desired release characteristics. Objective: The ongoing research purpose to improve the advancement of a sustained release tablet containing Phenothiazine derivative PCM loaded matrix. This is achieved by utilizing DoE as a computational method to statistically validate the formulation.]]>

Introduction: This study explores the use of Response Surface Methodology (RSM), a statistical optimization technique, to optimize the SR properties of prochlorperazine maleate (PCM) matrix tablets. PCM is a phenothiazine derivative used for treating schizophrenia, nausea, and vomiting. Sustained-release formulations offer extended drug delivery, potentially improving patient compliance and reducing side effects. RSM helps identify optimal combinations of critical formulation factors influencing drug release, such as polymer type and concentration, filler type, and drug/polymer ratio. The study likely involves designing experiments based on chosen RSM designs (e.g., Box-Behnken) with varying factor levels. Formulate SR tablets with different factor combinations. Evaluating the drug release profiles of each tablet formulation. Analyzing data using RSM software to build mathematical models relating factors to drug release and identifying optimal factor combinations that maximize desired release characteristics. Objective: The ongoing research purpose to improve the advancement of a sustained release tablet containing Phenothiazine derivative PCM loaded matrix. This is achieved by utilizing DoE as a computational method to statistically validate the formulation.]]>
Mon, 15 Jan 2024 06:55:49 GMT /slideshow/the-application-of-response-surface-methodology-rsm-in-the-computational-optimization-of-sustained-release-sr-for-phenothiazine-derivative-matrix-tablet/265420791 prachipandey924090@slideshare.net(prachipandey924090) The Application of Response Surface Methodology (RSM) In the Computational Optimization of Sustained Release (SR) For Phenothiazine Derivative Matrix Tablet prachipandey924090 Introduction: This study explores the use of Response Surface Methodology (RSM), a statistical optimization technique, to optimize the SR properties of prochlorperazine maleate (PCM) matrix tablets. PCM is a phenothiazine derivative used for treating schizophrenia, nausea, and vomiting. Sustained-release formulations offer extended drug delivery, potentially improving patient compliance and reducing side effects. RSM helps identify optimal combinations of critical formulation factors influencing drug release, such as polymer type and concentration, filler type, and drug/polymer ratio. The study likely involves designing experiments based on chosen RSM designs (e.g., Box-Behnken) with varying factor levels. Formulate SR tablets with different factor combinations. Evaluating the drug release profiles of each tablet formulation. Analyzing data using RSM software to build mathematical models relating factors to drug release and identifying optimal factor combinations that maximize desired release characteristics. Objective: The ongoing research purpose to improve the advancement of a sustained release tablet containing Phenothiazine derivative PCM loaded matrix. This is achieved by utilizing DoE as a computational method to statistically validate the formulation. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/thakur35352024jpri111654-240115065550-a4de0d46-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> Introduction: This study explores the use of Response Surface Methodology (RSM), a statistical optimization technique, to optimize the SR properties of prochlorperazine maleate (PCM) matrix tablets. PCM is a phenothiazine derivative used for treating schizophrenia, nausea, and vomiting. Sustained-release formulations offer extended drug delivery, potentially improving patient compliance and reducing side effects. RSM helps identify optimal combinations of critical formulation factors influencing drug release, such as polymer type and concentration, filler type, and drug/polymer ratio. The study likely involves designing experiments based on chosen RSM designs (e.g., Box-Behnken) with varying factor levels. Formulate SR tablets with different factor combinations. Evaluating the drug release profiles of each tablet formulation. Analyzing data using RSM software to build mathematical models relating factors to drug release and identifying optimal factor combinations that maximize desired release characteristics. Objective: The ongoing research purpose to improve the advancement of a sustained release tablet containing Phenothiazine derivative PCM loaded matrix. This is achieved by utilizing DoE as a computational method to statistically validate the formulation.
The Application of Response Surface Methodology (RSM) In the Computational Optimization of Sustained Release (SR) For Phenothiazine Derivative Matrix Tablet from Prachi Pandey
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The Utilization of 32 Full Factorial Design (FFD) for Optimization of Lincomycin Hydrochloride (LNH) Loaded Nanogel Involving; Design of Experiments (DoE) an Advanced Approach /slideshow/the-utilization-of-32-full-factorial-design-ffd-for-optimization-of-lincomycin-hydrochloride-lnh-loaded-nanogel-involving-design-of-experiments-doe-an-advanced-approach/265243460 pal2462023air110951-240109055945-43ac03df
Objectives: The ongoing research aims to enhance the development of LNH-loaded nanogel by utilizing DoE as the computational method to statistically validate their formulation. Methodology: In this research Chitosan used as a natural polymer and Poly (Ethylene glycol) [PEG] as a penetration or permeation enhancer. The different nanogel of LNH were synthesized using the Nanoprecipitation and Dispersion method, with variations in the drug-polymer ratio (1/0.03, 1/0.08, 1/0.12). The process parameters were carefully optimizing for enhance the efficiency of the synthesis. To achieve this, optimization studies were conducted using 3族 FFD, employing the Design Expert Software Trial version 10.0.7. The total of 13 runs were generated to ensure comprehensive analysis and evaluation of the procedure. The selected independent variables included the concentration of Chitosan (R1) and Carbopol 934 (R2). The dependent variables, on the other hand, were particle size (P1), Polydispersity Index (P2), and % Drug release (P3), chosen in that order. By employing this optimization technique, one can acquire valuable information in a manner that is both efficient and cost-effective. This approach facilitates a deeper comprehension of the relationship between controllable independent variables and the performance and quality of the Nanogels being produced]]>

Objectives: The ongoing research aims to enhance the development of LNH-loaded nanogel by utilizing DoE as the computational method to statistically validate their formulation. Methodology: In this research Chitosan used as a natural polymer and Poly (Ethylene glycol) [PEG] as a penetration or permeation enhancer. The different nanogel of LNH were synthesized using the Nanoprecipitation and Dispersion method, with variations in the drug-polymer ratio (1/0.03, 1/0.08, 1/0.12). The process parameters were carefully optimizing for enhance the efficiency of the synthesis. To achieve this, optimization studies were conducted using 3族 FFD, employing the Design Expert Software Trial version 10.0.7. The total of 13 runs were generated to ensure comprehensive analysis and evaluation of the procedure. The selected independent variables included the concentration of Chitosan (R1) and Carbopol 934 (R2). The dependent variables, on the other hand, were particle size (P1), Polydispersity Index (P2), and % Drug release (P3), chosen in that order. By employing this optimization technique, one can acquire valuable information in a manner that is both efficient and cost-effective. This approach facilitates a deeper comprehension of the relationship between controllable independent variables and the performance and quality of the Nanogels being produced]]>
Tue, 09 Jan 2024 05:59:45 GMT /slideshow/the-utilization-of-32-full-factorial-design-ffd-for-optimization-of-lincomycin-hydrochloride-lnh-loaded-nanogel-involving-design-of-experiments-doe-an-advanced-approach/265243460 prachipandey924090@slideshare.net(prachipandey924090) The Utilization of 32 Full Factorial Design (FFD) for Optimization of Lincomycin Hydrochloride (LNH) Loaded Nanogel Involving; Design of Experiments (DoE) an Advanced Approach prachipandey924090 Objectives: The ongoing research aims to enhance the development of LNH-loaded nanogel by utilizing DoE as the computational method to statistically validate their formulation. Methodology: In this research Chitosan used as a natural polymer and Poly (Ethylene glycol) [PEG] as a penetration or permeation enhancer. The different nanogel of LNH were synthesized using the Nanoprecipitation and Dispersion method, with variations in the drug-polymer ratio (1/0.03, 1/0.08, 1/0.12). The process parameters were carefully optimizing for enhance the efficiency of the synthesis. To achieve this, optimization studies were conducted using 3族 FFD, employing the Design Expert Software Trial version 10.0.7. The total of 13 runs were generated to ensure comprehensive analysis and evaluation of the procedure. The selected independent variables included the concentration of Chitosan (R1) and Carbopol 934 (R2). The dependent variables, on the other hand, were particle size (P1), Polydispersity Index (P2), and % Drug release (P3), chosen in that order. By employing this optimization technique, one can acquire valuable information in a manner that is both efficient and cost-effective. This approach facilitates a deeper comprehension of the relationship between controllable independent variables and the performance and quality of the Nanogels being produced <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/pal2462023air110951-240109055945-43ac03df-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> Objectives: The ongoing research aims to enhance the development of LNH-loaded nanogel by utilizing DoE as the computational method to statistically validate their formulation. Methodology: In this research Chitosan used as a natural polymer and Poly (Ethylene glycol) [PEG] as a penetration or permeation enhancer. The different nanogel of LNH were synthesized using the Nanoprecipitation and Dispersion method, with variations in the drug-polymer ratio (1/0.03, 1/0.08, 1/0.12). The process parameters were carefully optimizing for enhance the efficiency of the synthesis. To achieve this, optimization studies were conducted using 3族 FFD, employing the Design Expert Software Trial version 10.0.7. The total of 13 runs were generated to ensure comprehensive analysis and evaluation of the procedure. The selected independent variables included the concentration of Chitosan (R1) and Carbopol 934 (R2). The dependent variables, on the other hand, were particle size (P1), Polydispersity Index (P2), and % Drug release (P3), chosen in that order. By employing this optimization technique, one can acquire valuable information in a manner that is both efficient and cost-effective. This approach facilitates a deeper comprehension of the relationship between controllable independent variables and the performance and quality of the Nanogels being produced
The Utilization of 32 Full Factorial Design (FFD) for Optimization of Lincomycin Hydrochloride (LNH) Loaded Nanogel Involving; Design of Experiments (DoE) an Advanced Approach from Prachi Pandey
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Determination of Partition coefficient of Known and Unknown drug.pdf /slideshow/determination-of-partition-coefficient-of-known-and-unknown-drugpdf/265243415 determinationofpartitioncoefficientofknownandunknowndrug-240109055810-f09254d1
Partition coefficient, often denoted as P or P_oct, is a measure of how a solute distributes between two immiscible (unmixable) solvents. It is commonly used in chemistry, biochemistry, and pharmacology to understand the distribution of a compound between different phases, such as between a hydrophobic organic solvent and water. In experimental settings, the partition coefficient is determined by measuring the concentrations of the solute in each phase. The values obtained provide insights into the solute's behavior and can guide decisions in various scientific and industrial processes.]]>

Partition coefficient, often denoted as P or P_oct, is a measure of how a solute distributes between two immiscible (unmixable) solvents. It is commonly used in chemistry, biochemistry, and pharmacology to understand the distribution of a compound between different phases, such as between a hydrophobic organic solvent and water. In experimental settings, the partition coefficient is determined by measuring the concentrations of the solute in each phase. The values obtained provide insights into the solute's behavior and can guide decisions in various scientific and industrial processes.]]>
Tue, 09 Jan 2024 05:58:10 GMT /slideshow/determination-of-partition-coefficient-of-known-and-unknown-drugpdf/265243415 prachipandey924090@slideshare.net(prachipandey924090) Determination of Partition coefficient of Known and Unknown drug.pdf prachipandey924090 Partition coefficient, often denoted as P or P_oct, is a measure of how a solute distributes between two immiscible (unmixable) solvents. It is commonly used in chemistry, biochemistry, and pharmacology to understand the distribution of a compound between different phases, such as between a hydrophobic organic solvent and water. In experimental settings, the partition coefficient is determined by measuring the concentrations of the solute in each phase. The values obtained provide insights into the solute's behavior and can guide decisions in various scientific and industrial processes. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/determinationofpartitioncoefficientofknownandunknowndrug-240109055810-f09254d1-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> Partition coefficient, often denoted as P or P_oct, is a measure of how a solute distributes between two immiscible (unmixable) solvents. It is commonly used in chemistry, biochemistry, and pharmacology to understand the distribution of a compound between different phases, such as between a hydrophobic organic solvent and water. In experimental settings, the partition coefficient is determined by measuring the concentrations of the solute in each phase. The values obtained provide insights into the solute&#39;s behavior and can guide decisions in various scientific and industrial processes.
Determination of Partition coefficient of Known and Unknown drug.pdf from Prachi Pandey
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Pharmaceutical Suspension Dosage Form (PPT) /slideshow/pharmaceutical-suspension-dosage-form-ppt/265074127 suspension-240102145008-262663de
A pharmaceutical suspension is a heterogeneous system in which finely divided solid particles are dispersed in a liquid medium. Unlike solutions, where solutes are completely dissolved, suspensions involve particles that are only partially soluble or insoluble in the liquid. These suspensions are commonly used in the pharmaceutical industry to deliver medications that may be poorly soluble or unstable in their pure form. The solid particles, often in the form of powders or crystals, are dispersed throughout the liquid phase, creating a stable mixture through the use of suspending agents or stabilizers. These agents prevent the settling of particles, ensuring uniform distribution and ease of redispersion upon shaking before administration. Pharmaceutical suspensions offer advantages in terms of flexibility in dosing and formulation, enabling the delivery of therapeutic agents in various forms such as oral liquids, injectables, or topical preparations, enhancing patient compliance and therapeutic efficacy. The formulation and stability of pharmaceutical suspensions require careful consideration of factors such as particle size, density, and the choice of stabilizers to maintain a consistent and reliable product.]]>

A pharmaceutical suspension is a heterogeneous system in which finely divided solid particles are dispersed in a liquid medium. Unlike solutions, where solutes are completely dissolved, suspensions involve particles that are only partially soluble or insoluble in the liquid. These suspensions are commonly used in the pharmaceutical industry to deliver medications that may be poorly soluble or unstable in their pure form. The solid particles, often in the form of powders or crystals, are dispersed throughout the liquid phase, creating a stable mixture through the use of suspending agents or stabilizers. These agents prevent the settling of particles, ensuring uniform distribution and ease of redispersion upon shaking before administration. Pharmaceutical suspensions offer advantages in terms of flexibility in dosing and formulation, enabling the delivery of therapeutic agents in various forms such as oral liquids, injectables, or topical preparations, enhancing patient compliance and therapeutic efficacy. The formulation and stability of pharmaceutical suspensions require careful consideration of factors such as particle size, density, and the choice of stabilizers to maintain a consistent and reliable product.]]>
Tue, 02 Jan 2024 14:50:08 GMT /slideshow/pharmaceutical-suspension-dosage-form-ppt/265074127 prachipandey924090@slideshare.net(prachipandey924090) Pharmaceutical Suspension Dosage Form (PPT) prachipandey924090 A pharmaceutical suspension is a heterogeneous system in which finely divided solid particles are dispersed in a liquid medium. Unlike solutions, where solutes are completely dissolved, suspensions involve particles that are only partially soluble or insoluble in the liquid. These suspensions are commonly used in the pharmaceutical industry to deliver medications that may be poorly soluble or unstable in their pure form. The solid particles, often in the form of powders or crystals, are dispersed throughout the liquid phase, creating a stable mixture through the use of suspending agents or stabilizers. These agents prevent the settling of particles, ensuring uniform distribution and ease of redispersion upon shaking before administration. Pharmaceutical suspensions offer advantages in terms of flexibility in dosing and formulation, enabling the delivery of therapeutic agents in various forms such as oral liquids, injectables, or topical preparations, enhancing patient compliance and therapeutic efficacy. The formulation and stability of pharmaceutical suspensions require careful consideration of factors such as particle size, density, and the choice of stabilizers to maintain a consistent and reliable product. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/suspension-240102145008-262663de-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> A pharmaceutical suspension is a heterogeneous system in which finely divided solid particles are dispersed in a liquid medium. Unlike solutions, where solutes are completely dissolved, suspensions involve particles that are only partially soluble or insoluble in the liquid. These suspensions are commonly used in the pharmaceutical industry to deliver medications that may be poorly soluble or unstable in their pure form. The solid particles, often in the form of powders or crystals, are dispersed throughout the liquid phase, creating a stable mixture through the use of suspending agents or stabilizers. These agents prevent the settling of particles, ensuring uniform distribution and ease of redispersion upon shaking before administration. Pharmaceutical suspensions offer advantages in terms of flexibility in dosing and formulation, enabling the delivery of therapeutic agents in various forms such as oral liquids, injectables, or topical preparations, enhancing patient compliance and therapeutic efficacy. The formulation and stability of pharmaceutical suspensions require careful consideration of factors such as particle size, density, and the choice of stabilizers to maintain a consistent and reliable product.
Pharmaceutical Suspension Dosage Form (PPT) from Prachi Pandey
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PHARMACEUTICAL SUPPOSITORIES & PESSARIES.ppt /slideshow/pharmaceutical-suppositories-pessariesppt/264815064 pharmaceuticalsuppositoriespessaries-231221050644-a96726f4
Suppositories and pessaries are both types of medication delivery systems that are designed to be inserted into body orifices for therapeutic purposes. While they serve similar functions, they are used in different parts of the body. Suppositories: Usage: Suppositories are typically designed for rectal or vaginal administration. Composition: They are solid, bullet-shaped or cone-shaped dosage forms that contain medication in a base that melts or dissolves at body temperature. Rectal Suppositories: Commonly used for medications that need to bypass the digestive system or when a patient cannot take medications orally. They are inserted into the rectum. Vaginal Suppositories: Often used for localized treatment of gynecological conditions, such as yeast infections or hormonal therapy. They are inserted into the vagina. Pessaries: Usage: Pessaries are specifically designed for vaginal administration. Composition: They are solid, oval-shaped or ring-shaped devices made of various materials such as silicone, rubber, or plastic. Indications: Pessaries are mainly used to support the uterus, bladder, or rectum in cases of pelvic organ prolapse. However, they can also be used for the controlled release of medication into the vagina for the treatment of local conditions. Maintenance: Pessaries need to be fitted by a healthcare professional and should be cleaned and reinserted regularly.]]>

Suppositories and pessaries are both types of medication delivery systems that are designed to be inserted into body orifices for therapeutic purposes. While they serve similar functions, they are used in different parts of the body. Suppositories: Usage: Suppositories are typically designed for rectal or vaginal administration. Composition: They are solid, bullet-shaped or cone-shaped dosage forms that contain medication in a base that melts or dissolves at body temperature. Rectal Suppositories: Commonly used for medications that need to bypass the digestive system or when a patient cannot take medications orally. They are inserted into the rectum. Vaginal Suppositories: Often used for localized treatment of gynecological conditions, such as yeast infections or hormonal therapy. They are inserted into the vagina. Pessaries: Usage: Pessaries are specifically designed for vaginal administration. Composition: They are solid, oval-shaped or ring-shaped devices made of various materials such as silicone, rubber, or plastic. Indications: Pessaries are mainly used to support the uterus, bladder, or rectum in cases of pelvic organ prolapse. However, they can also be used for the controlled release of medication into the vagina for the treatment of local conditions. Maintenance: Pessaries need to be fitted by a healthcare professional and should be cleaned and reinserted regularly.]]>
Thu, 21 Dec 2023 05:06:44 GMT /slideshow/pharmaceutical-suppositories-pessariesppt/264815064 prachipandey924090@slideshare.net(prachipandey924090) PHARMACEUTICAL SUPPOSITORIES & PESSARIES.ppt prachipandey924090 Suppositories and pessaries are both types of medication delivery systems that are designed to be inserted into body orifices for therapeutic purposes. While they serve similar functions, they are used in different parts of the body. Suppositories: Usage: Suppositories are typically designed for rectal or vaginal administration. Composition: They are solid, bullet-shaped or cone-shaped dosage forms that contain medication in a base that melts or dissolves at body temperature. Rectal Suppositories: Commonly used for medications that need to bypass the digestive system or when a patient cannot take medications orally. They are inserted into the rectum. Vaginal Suppositories: Often used for localized treatment of gynecological conditions, such as yeast infections or hormonal therapy. They are inserted into the vagina. Pessaries: Usage: Pessaries are specifically designed for vaginal administration. Composition: They are solid, oval-shaped or ring-shaped devices made of various materials such as silicone, rubber, or plastic. Indications: Pessaries are mainly used to support the uterus, bladder, or rectum in cases of pelvic organ prolapse. However, they can also be used for the controlled release of medication into the vagina for the treatment of local conditions. Maintenance: Pessaries need to be fitted by a healthcare professional and should be cleaned and reinserted regularly. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/pharmaceuticalsuppositoriespessaries-231221050644-a96726f4-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> Suppositories and pessaries are both types of medication delivery systems that are designed to be inserted into body orifices for therapeutic purposes. While they serve similar functions, they are used in different parts of the body. Suppositories: Usage: Suppositories are typically designed for rectal or vaginal administration. Composition: They are solid, bullet-shaped or cone-shaped dosage forms that contain medication in a base that melts or dissolves at body temperature. Rectal Suppositories: Commonly used for medications that need to bypass the digestive system or when a patient cannot take medications orally. They are inserted into the rectum. Vaginal Suppositories: Often used for localized treatment of gynecological conditions, such as yeast infections or hormonal therapy. They are inserted into the vagina. Pessaries: Usage: Pessaries are specifically designed for vaginal administration. Composition: They are solid, oval-shaped or ring-shaped devices made of various materials such as silicone, rubber, or plastic. Indications: Pessaries are mainly used to support the uterus, bladder, or rectum in cases of pelvic organ prolapse. However, they can also be used for the controlled release of medication into the vagina for the treatment of local conditions. Maintenance: Pessaries need to be fitted by a healthcare professional and should be cleaned and reinserted regularly.
PHARMACEUTICAL SUPPOSITORIES & PESSARIES.ppt from Prachi Pandey
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Partition Coefficient Determination.pptx /slideshow/partition-coefficient-determinationpptx/264760413 partitioncoefficientdetermination-231219045909-f35878ed
Partition coefficients are a fascinating and important concept in many fields, from chemistry and environmental science to medicine and pharmacology. They tell us about how a substance will distribute itself between two immiscible phases, like how a drug might move between your blood and tissues, or how a pollutant might spread through soil and water. A partition coefficient, denoted as P or log P, describes the ratio of the concentration of a compound in one phase (usually organic) to its concentration in another phase (often water) at equilibrium. Higher values of P indicate a greater preference for the organic phase, meaning the compound is more lipophilic (fat-loving). Lower values of P suggest a higher affinity for the aqueous phase, implying the compound is more hydrophilic (water-loving).]]>

Partition coefficients are a fascinating and important concept in many fields, from chemistry and environmental science to medicine and pharmacology. They tell us about how a substance will distribute itself between two immiscible phases, like how a drug might move between your blood and tissues, or how a pollutant might spread through soil and water. A partition coefficient, denoted as P or log P, describes the ratio of the concentration of a compound in one phase (usually organic) to its concentration in another phase (often water) at equilibrium. Higher values of P indicate a greater preference for the organic phase, meaning the compound is more lipophilic (fat-loving). Lower values of P suggest a higher affinity for the aqueous phase, implying the compound is more hydrophilic (water-loving).]]>
Tue, 19 Dec 2023 04:59:09 GMT /slideshow/partition-coefficient-determinationpptx/264760413 prachipandey924090@slideshare.net(prachipandey924090) Partition Coefficient Determination.pptx prachipandey924090 Partition coefficients are a fascinating and important concept in many fields, from chemistry and environmental science to medicine and pharmacology. They tell us about how a substance will distribute itself between two immiscible phases, like how a drug might move between your blood and tissues, or how a pollutant might spread through soil and water. A partition coefficient, denoted as P or log P, describes the ratio of the concentration of a compound in one phase (usually organic) to its concentration in another phase (often water) at equilibrium. Higher values of P indicate a greater preference for the organic phase, meaning the compound is more lipophilic (fat-loving). Lower values of P suggest a higher affinity for the aqueous phase, implying the compound is more hydrophilic (water-loving). <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/partitioncoefficientdetermination-231219045909-f35878ed-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> Partition coefficients are a fascinating and important concept in many fields, from chemistry and environmental science to medicine and pharmacology. They tell us about how a substance will distribute itself between two immiscible phases, like how a drug might move between your blood and tissues, or how a pollutant might spread through soil and water. A partition coefficient, denoted as P or log P, describes the ratio of the concentration of a compound in one phase (usually organic) to its concentration in another phase (often water) at equilibrium. Higher values of P indicate a greater preference for the organic phase, meaning the compound is more lipophilic (fat-loving). Lower values of P suggest a higher affinity for the aqueous phase, implying the compound is more hydrophilic (water-loving).
Partition Coefficient Determination.pptx from Prachi Pandey
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Research Methodology_UNIT_V_Declaration of Helsinki M. Pharm (IIIrd Sem.) /slideshow/research-methodologyunitvdeclaration-of-helsinki-m-pharm-iiird-sem/264422428 declarationofhelsinkiunitvrmmrm301t-231207160117-888b75c4
Declaration of Helsinki: History, introduction, basic principles for all medical research, and additional principles for medical research combined with medical care.]]>

Declaration of Helsinki: History, introduction, basic principles for all medical research, and additional principles for medical research combined with medical care.]]>
Thu, 07 Dec 2023 16:01:17 GMT /slideshow/research-methodologyunitvdeclaration-of-helsinki-m-pharm-iiird-sem/264422428 prachipandey924090@slideshare.net(prachipandey924090) Research Methodology_UNIT_V_Declaration of Helsinki M. Pharm (IIIrd Sem.) prachipandey924090 Declaration of Helsinki: History, introduction, basic principles for all medical research, and additional principles for medical research combined with medical care. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/declarationofhelsinkiunitvrmmrm301t-231207160117-888b75c4-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> Declaration of Helsinki: History, introduction, basic principles for all medical research, and additional principles for medical research combined with medical care.
Research Methodology_UNIT_V_Declaration of Helsinki M. Pharm (IIIrd Sem.) from Prachi Pandey
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Research Methodology_UNIT_I_General Research Methodology M. Pharm (IIIrd Sem.) /slideshow/general-research-methodology-iiird-sem-m-pharmpptx/264302281 generalresearchmethodologyiiirdsemm-231205055627-e12ba4d2
General Research Methodology: Research, objective, requirements, practical difficulties, review of literature, study design, types of studies, strategies to eliminate errors/bias, controls, randomization, crossover design, placebo, blinding techniques.]]>

General Research Methodology: Research, objective, requirements, practical difficulties, review of literature, study design, types of studies, strategies to eliminate errors/bias, controls, randomization, crossover design, placebo, blinding techniques.]]>
Tue, 05 Dec 2023 05:56:27 GMT /slideshow/general-research-methodology-iiird-sem-m-pharmpptx/264302281 prachipandey924090@slideshare.net(prachipandey924090) Research Methodology_UNIT_I_General Research Methodology M. Pharm (IIIrd Sem.) prachipandey924090 General Research Methodology: Research, objective, requirements, practical difficulties, review of literature, study design, types of studies, strategies to eliminate errors/bias, controls, randomization, crossover design, placebo, blinding techniques. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/generalresearchmethodologyiiirdsemm-231205055627-e12ba4d2-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> General Research Methodology: Research, objective, requirements, practical difficulties, review of literature, study design, types of studies, strategies to eliminate errors/bias, controls, randomization, crossover design, placebo, blinding techniques.
Research Methodology_UNIT_I_General Research Methodology M. Pharm (IIIrd Sem.) from Prachi Pandey
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THE CURRENT STATUS IN MUCOSALDRUG DELIVERY SYSTEM (MDDS)AND FUTURE PROSPECTUS INDELIVERY: A SYSTEMATIC REVIEW /slideshow/the-current-status-in-mucosaldrug-delivery-system-mddsand-future-prospectus-indelivery-a-systematic-review/264301533 v8i1009-231205053045-549c8ab6
This systematic review aims to provide a comprehensive overview of the current status of mucosal drug delivery systems (MDDS) and explore their future prospects in drug delivery. MDDS have gained significant attention in recent years due to their potential to enhance drug absorption, improve therapeutic efficacy, and minimize systemic side effects. This review critically evaluates the existing literature on MDDS, including various mucosal routes such as oral, nasal, ocular, pulmonary, and vaginal delivery. Additionally, it discusses the challenges associated with MDDS, such as formulation development, stability, and regulatory considerations. Furthermore, this review highlights emerging technologies and innovative strategies that hold promise for the future of MDDS. Overall, this systematic review provides valuable insights into the current landscape of MDDS and offers recommendations for future research and development in this field.]]>

This systematic review aims to provide a comprehensive overview of the current status of mucosal drug delivery systems (MDDS) and explore their future prospects in drug delivery. MDDS have gained significant attention in recent years due to their potential to enhance drug absorption, improve therapeutic efficacy, and minimize systemic side effects. This review critically evaluates the existing literature on MDDS, including various mucosal routes such as oral, nasal, ocular, pulmonary, and vaginal delivery. Additionally, it discusses the challenges associated with MDDS, such as formulation development, stability, and regulatory considerations. Furthermore, this review highlights emerging technologies and innovative strategies that hold promise for the future of MDDS. Overall, this systematic review provides valuable insights into the current landscape of MDDS and offers recommendations for future research and development in this field.]]>
Tue, 05 Dec 2023 05:30:44 GMT /slideshow/the-current-status-in-mucosaldrug-delivery-system-mddsand-future-prospectus-indelivery-a-systematic-review/264301533 prachipandey924090@slideshare.net(prachipandey924090) THE CURRENT STATUS IN MUCOSALDRUG DELIVERY SYSTEM (MDDS)AND FUTURE PROSPECTUS INDELIVERY: A SYSTEMATIC REVIEW prachipandey924090 This systematic review aims to provide a comprehensive overview of the current status of mucosal drug delivery systems (MDDS) and explore their future prospects in drug delivery. MDDS have gained significant attention in recent years due to their potential to enhance drug absorption, improve therapeutic efficacy, and minimize systemic side effects. This review critically evaluates the existing literature on MDDS, including various mucosal routes such as oral, nasal, ocular, pulmonary, and vaginal delivery. Additionally, it discusses the challenges associated with MDDS, such as formulation development, stability, and regulatory considerations. Furthermore, this review highlights emerging technologies and innovative strategies that hold promise for the future of MDDS. Overall, this systematic review provides valuable insights into the current landscape of MDDS and offers recommendations for future research and development in this field. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/v8i1009-231205053045-549c8ab6-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> This systematic review aims to provide a comprehensive overview of the current status of mucosal drug delivery systems (MDDS) and explore their future prospects in drug delivery. MDDS have gained significant attention in recent years due to their potential to enhance drug absorption, improve therapeutic efficacy, and minimize systemic side effects. This review critically evaluates the existing literature on MDDS, including various mucosal routes such as oral, nasal, ocular, pulmonary, and vaginal delivery. Additionally, it discusses the challenges associated with MDDS, such as formulation development, stability, and regulatory considerations. Furthermore, this review highlights emerging technologies and innovative strategies that hold promise for the future of MDDS. Overall, this systematic review provides valuable insights into the current landscape of MDDS and offers recommendations for future research and development in this field.
THE CURRENT STATUS IN MUCOSALDRUG DELIVERY SYSTEM (MDDS)AND FUTURE PROSPECTUS INDELIVERY: A SYSTEMATIC REVIEW from Prachi Pandey
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Research Methodology (M. Pharm, IIIrd Sem.)_UNIT_IV_CPCSEA Guidelines for Laboratory animal facility.pptx /slideshow/research-methodology-m-pharm-iiird-semunitivcpcsea-guidelines-for-laboratory-animal-facilitypptx/264300970 cpcseaguidelinesforlaboratoryanimalfacility-231205051041-375bcaef
CPCSEA guidelines for laboratory animal facility: Goals, veterinary care, quarantine, surveillance, diagnosis, treatment and control of disease, personal hygiene, location of animal facilities to laboratories, anesthesia, euthanasia, physical facilities, environment, animal husbandry, record keeping, SOPs, personnel and training, transport of lab animals.]]>

CPCSEA guidelines for laboratory animal facility: Goals, veterinary care, quarantine, surveillance, diagnosis, treatment and control of disease, personal hygiene, location of animal facilities to laboratories, anesthesia, euthanasia, physical facilities, environment, animal husbandry, record keeping, SOPs, personnel and training, transport of lab animals.]]>
Tue, 05 Dec 2023 05:10:40 GMT /slideshow/research-methodology-m-pharm-iiird-semunitivcpcsea-guidelines-for-laboratory-animal-facilitypptx/264300970 prachipandey924090@slideshare.net(prachipandey924090) Research Methodology (M. Pharm, IIIrd Sem.)_UNIT_IV_CPCSEA Guidelines for Laboratory animal facility.pptx prachipandey924090 CPCSEA guidelines for laboratory animal facility: Goals, veterinary care, quarantine, surveillance, diagnosis, treatment and control of disease, personal hygiene, location of animal facilities to laboratories, anesthesia, euthanasia, physical facilities, environment, animal husbandry, record keeping, SOPs, personnel and training, transport of lab animals. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/cpcseaguidelinesforlaboratoryanimalfacility-231205051041-375bcaef-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> CPCSEA guidelines for laboratory animal facility: Goals, veterinary care, quarantine, surveillance, diagnosis, treatment and control of disease, personal hygiene, location of animal facilities to laboratories, anesthesia, euthanasia, physical facilities, environment, animal husbandry, record keeping, SOPs, personnel and training, transport of lab animals.
Research Methodology (M. Pharm, IIIrd Sem.)_UNIT_IV_CPCSEA Guidelines for Laboratory animal facility.pptx from Prachi Pandey
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ProductManagement-InventroyManagementandControls.pptx /slideshow/productmanagementinventroymanagementandcontrolspptx/264187744 productmanagement-inventroymanagementandcontrols-231202053258-228eff23
Operations management is an area of management concerned with designing and controlling the process of production and redesigning business operations in the production of goods or services.]]>

Operations management is an area of management concerned with designing and controlling the process of production and redesigning business operations in the production of goods or services.]]>
Sat, 02 Dec 2023 05:32:57 GMT /slideshow/productmanagementinventroymanagementandcontrolspptx/264187744 prachipandey924090@slideshare.net(prachipandey924090) ProductManagement-InventroyManagementandControls.pptx prachipandey924090 Operations management is an area of management concerned with designing and controlling the process of production and redesigning business operations in the production of goods or services. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/productmanagement-inventroymanagementandcontrols-231202053258-228eff23-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> Operations management is an area of management concerned with designing and controlling the process of production and redesigning business operations in the production of goods or services.
ProductManagement-InventroyManagementandControls.pptx from Prachi Pandey
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IMPORTSOFDRUGS.pptx /prachipandey924090/importsofdrugspptx importsofdrugs-231202053058-ada3ad23
The application for Registration and import can be made to the Licensing Authority under the Act i.e. to the Drugs Controller General at CDSCO. Drug and Cosmetic Act 1945: It Contains provisions for classification of drugs under given schedules. Guidelines for the storage,sale,display and prescription of each schedule.]]>

The application for Registration and import can be made to the Licensing Authority under the Act i.e. to the Drugs Controller General at CDSCO. Drug and Cosmetic Act 1945: It Contains provisions for classification of drugs under given schedules. Guidelines for the storage,sale,display and prescription of each schedule.]]>
Sat, 02 Dec 2023 05:30:57 GMT /prachipandey924090/importsofdrugspptx prachipandey924090@slideshare.net(prachipandey924090) IMPORTSOFDRUGS.pptx prachipandey924090 The application for Registration and import can be made to the Licensing Authority under the Act i.e. to the Drugs Controller General at CDSCO. Drug and Cosmetic Act 1945: It Contains provisions for classification of drugs under given schedules. Guidelines for the storage,sale,display and prescription of each schedule. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/importsofdrugs-231202053058-ada3ad23-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> The application for Registration and import can be made to the Licensing Authority under the Act i.e. to the Drugs Controller General at CDSCO. Drug and Cosmetic Act 1945: It Contains provisions for classification of drugs under given schedules. Guidelines for the storage,sale,display and prescription of each schedule.
IMPORTSOFDRUGS.pptx from Prachi Pandey
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MicrospheresPreparationandEvaluations.pptx /slideshow/microspherespreparationandevaluationspptx/264187645 microspherespreparationandevaluations-231202052853-23c58161
Microspheres are small spherical particles, with diameter 1 袖m to 1000 袖m. They are spherical free flowing particles consisting of proteins or synthetic polymers which are biodegradable in nature. ]]>

Microspheres are small spherical particles, with diameter 1 袖m to 1000 袖m. They are spherical free flowing particles consisting of proteins or synthetic polymers which are biodegradable in nature. ]]>
Sat, 02 Dec 2023 05:28:53 GMT /slideshow/microspherespreparationandevaluationspptx/264187645 prachipandey924090@slideshare.net(prachipandey924090) MicrospheresPreparationandEvaluations.pptx prachipandey924090 Microspheres are small spherical particles, with diameter 1 袖m to 1000 袖m. They are spherical free flowing particles consisting of proteins or synthetic polymers which are biodegradable in nature. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/microspherespreparationandevaluations-231202052853-23c58161-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> Microspheres are small spherical particles, with diameter 1 袖m to 1000 袖m. They are spherical free flowing particles consisting of proteins or synthetic polymers which are biodegradable in nature.
MicrospheresPreparationandEvaluations.pptx from Prachi Pandey
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Protein and Peptide.pptx /slideshow/protein-and-peptidepptx/264187445 proteinandpeptide-231202052221-8f4b85a0
PROTEINS: Proteins are the large organic compounds made of amino acids arranged in a linear chain and joined together by peptide bonds. Protein > 50 amino acids PEPTIDES: These are short polymers formed from the linking, in a defined order of amino acids. Peptide < 50 amino acids ]]>

PROTEINS: Proteins are the large organic compounds made of amino acids arranged in a linear chain and joined together by peptide bonds. Protein > 50 amino acids PEPTIDES: These are short polymers formed from the linking, in a defined order of amino acids. Peptide < 50 amino acids ]]>
Sat, 02 Dec 2023 05:22:20 GMT /slideshow/protein-and-peptidepptx/264187445 prachipandey924090@slideshare.net(prachipandey924090) Protein and Peptide.pptx prachipandey924090 PROTEINS: Proteins are the large organic compounds made of amino acids arranged in a linear chain and joined together by peptide bonds. Protein > 50 amino acids PEPTIDES: These are short polymers formed from the linking, in a defined order of amino acids. Peptide < 50 amino acids <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/proteinandpeptide-231202052221-8f4b85a0-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> PROTEINS: Proteins are the large organic compounds made of amino acids arranged in a linear chain and joined together by peptide bonds. Protein &gt; 50 amino acids PEPTIDES: These are short polymers formed from the linking, in a defined order of amino acids. Peptide &lt; 50 amino acids
Protein and Peptide.pptx from Prachi Pandey
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NanoTechnology3DEuropeanChemicalBulletin.pdf /slideshow/nanotechnology3deuropeanchemicalbulletinpdf/264187285 nanotechnology3deuropeanchemicalbulletin-231202051806-0784b9ee
Three-dimensional (3-D) printing is elevating various growth in production viewpoint both at nanoscale and macro-scales. 3-D printing is being scouted for numerous bio-pharmaceutical administration and creation of nano-medicines employing supplementary production methods and shows assurance in capability in satisfying the demands for a patient-based customized approach. The previous outcome features the accessibility of novel natural bio-materials and finely designed polymeric substances, which can be created as unique 3-D printed nano-materials for numerous bio-pharmaceutical administrations as nano-medicines. Nano-medicine is described as the utilization of nanoscience in fabricating nano-materials for various pharmaceutical utilization, comprising identification, cure, scan, stopping, and management of diseases. Nano-medicine has also displayed a huge effect in the creation and evolve an accurate drug. In contrary the "one-size-fits-all" benchmark for the traditional drug is a personalized, structured, or accurate drug considering the variation in numerous characteristics, comprising genetics and pharmacokinetics of various victims, which have exhibited better outcomes over traditional cures. This article highlights the approaches advancements in the design and development of customized-made nano-medicine employing 3-D printing science.]]>

Three-dimensional (3-D) printing is elevating various growth in production viewpoint both at nanoscale and macro-scales. 3-D printing is being scouted for numerous bio-pharmaceutical administration and creation of nano-medicines employing supplementary production methods and shows assurance in capability in satisfying the demands for a patient-based customized approach. The previous outcome features the accessibility of novel natural bio-materials and finely designed polymeric substances, which can be created as unique 3-D printed nano-materials for numerous bio-pharmaceutical administrations as nano-medicines. Nano-medicine is described as the utilization of nanoscience in fabricating nano-materials for various pharmaceutical utilization, comprising identification, cure, scan, stopping, and management of diseases. Nano-medicine has also displayed a huge effect in the creation and evolve an accurate drug. In contrary the "one-size-fits-all" benchmark for the traditional drug is a personalized, structured, or accurate drug considering the variation in numerous characteristics, comprising genetics and pharmacokinetics of various victims, which have exhibited better outcomes over traditional cures. This article highlights the approaches advancements in the design and development of customized-made nano-medicine employing 3-D printing science.]]>
Sat, 02 Dec 2023 05:18:06 GMT /slideshow/nanotechnology3deuropeanchemicalbulletinpdf/264187285 prachipandey924090@slideshare.net(prachipandey924090) NanoTechnology3DEuropeanChemicalBulletin.pdf prachipandey924090 Three-dimensional (3-D) printing is elevating various growth in production viewpoint both at nanoscale and macro-scales. 3-D printing is being scouted for numerous bio-pharmaceutical administration and creation of nano-medicines employing supplementary production methods and shows assurance in capability in satisfying the demands for a patient-based customized approach. The previous outcome features the accessibility of novel natural bio-materials and finely designed polymeric substances, which can be created as unique 3-D printed nano-materials for numerous bio-pharmaceutical administrations as nano-medicines. Nano-medicine is described as the utilization of nanoscience in fabricating nano-materials for various pharmaceutical utilization, comprising identification, cure, scan, stopping, and management of diseases. Nano-medicine has also displayed a huge effect in the creation and evolve an accurate drug. In contrary the "one-size-fits-all" benchmark for the traditional drug is a personalized, structured, or accurate drug considering the variation in numerous characteristics, comprising genetics and pharmacokinetics of various victims, which have exhibited better outcomes over traditional cures. This article highlights the approaches advancements in the design and development of customized-made nano-medicine employing 3-D printing science. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/nanotechnology3deuropeanchemicalbulletin-231202051806-0784b9ee-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> Three-dimensional (3-D) printing is elevating various growth in production viewpoint both at nanoscale and macro-scales. 3-D printing is being scouted for numerous bio-pharmaceutical administration and creation of nano-medicines employing supplementary production methods and shows assurance in capability in satisfying the demands for a patient-based customized approach. The previous outcome features the accessibility of novel natural bio-materials and finely designed polymeric substances, which can be created as unique 3-D printed nano-materials for numerous bio-pharmaceutical administrations as nano-medicines. Nano-medicine is described as the utilization of nanoscience in fabricating nano-materials for various pharmaceutical utilization, comprising identification, cure, scan, stopping, and management of diseases. Nano-medicine has also displayed a huge effect in the creation and evolve an accurate drug. In contrary the &quot;one-size-fits-all&quot; benchmark for the traditional drug is a personalized, structured, or accurate drug considering the variation in numerous characteristics, comprising genetics and pharmacokinetics of various victims, which have exhibited better outcomes over traditional cures. This article highlights the approaches advancements in the design and development of customized-made nano-medicine employing 3-D printing science.
NanoTechnology3DEuropeanChemicalBulletin.pdf from Prachi Pandey
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TOTAL QUALITY MANAGEMENT, BUDGET & COST CONTROL.pptx /prachipandey924090/total-quality-management-budget-cost-controlpptx totalqualitymanagementbudgetcostcontrol-231202051612-7eb15695
Definition: TQM has been defined as an integrated organization effort designed to improve quality at every level. The process to produce a perfect product by a series of measures require an organized effort by the entire company to prevent or eliminate errors at every stage in production is called Total Quality Management (TQM). The Aim of TQM is Prevention of defect rather than detection on defect. TQM is very important for pharmaceutical industries to produce the better product and ensure the maximum safety of health care system and also protect waste of money for both government and individual customer. ]]>

Definition: TQM has been defined as an integrated organization effort designed to improve quality at every level. The process to produce a perfect product by a series of measures require an organized effort by the entire company to prevent or eliminate errors at every stage in production is called Total Quality Management (TQM). The Aim of TQM is Prevention of defect rather than detection on defect. TQM is very important for pharmaceutical industries to produce the better product and ensure the maximum safety of health care system and also protect waste of money for both government and individual customer. ]]>
Sat, 02 Dec 2023 05:16:12 GMT /prachipandey924090/total-quality-management-budget-cost-controlpptx prachipandey924090@slideshare.net(prachipandey924090) TOTAL QUALITY MANAGEMENT, BUDGET & COST CONTROL.pptx prachipandey924090 Definition: TQM has been defined as an integrated organization effort designed to improve quality at every level. The process to produce a perfect product by a series of measures require an organized effort by the entire company to prevent or eliminate errors at every stage in production is called Total Quality Management (TQM). The Aim of TQM is Prevention of defect rather than detection on defect. TQM is very important for pharmaceutical industries to produce the better product and ensure the maximum safety of health care system and also protect waste of money for both government and individual customer. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/totalqualitymanagementbudgetcostcontrol-231202051612-7eb15695-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> Definition: TQM has been defined as an integrated organization effort designed to improve quality at every level. The process to produce a perfect product by a series of measures require an organized effort by the entire company to prevent or eliminate errors at every stage in production is called Total Quality Management (TQM). The Aim of TQM is Prevention of defect rather than detection on defect. TQM is very important for pharmaceutical industries to produce the better product and ensure the maximum safety of health care system and also protect waste of money for both government and individual customer.
TOTAL QUALITY MANAGEMENT, BUDGET & COST CONTROL.pptx from Prachi Pandey
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IntroductiontoPharmacyPharmaceutics.pptx /slideshow/introductiontopharmacypharmaceuticspptx/264187151 introductiontopharmacypharmaceutics-231202051409-65414bfa
The word pharmacy is derived from the Greek word Pharmakon, meaning medicine or drug. In other term, Pharmacy may defined as the art and science of preparing (manufacturing) and dispensing of drugs prepared by the natural and synthetic sources and using for the treatment as well as prevention of diseases. In general sense, it is the place where medicine or drugs are sold. Pharmacy is a health profession that links health science with chemical science and aims to ensure the safe and effective use of pharmaceutical drugs. It includes the collection, identification, synthesis, purification, isolation and quality control of medical substance or pharmaceutical products.]]>

The word pharmacy is derived from the Greek word Pharmakon, meaning medicine or drug. In other term, Pharmacy may defined as the art and science of preparing (manufacturing) and dispensing of drugs prepared by the natural and synthetic sources and using for the treatment as well as prevention of diseases. In general sense, it is the place where medicine or drugs are sold. Pharmacy is a health profession that links health science with chemical science and aims to ensure the safe and effective use of pharmaceutical drugs. It includes the collection, identification, synthesis, purification, isolation and quality control of medical substance or pharmaceutical products.]]>
Sat, 02 Dec 2023 05:14:09 GMT /slideshow/introductiontopharmacypharmaceuticspptx/264187151 prachipandey924090@slideshare.net(prachipandey924090) IntroductiontoPharmacyPharmaceutics.pptx prachipandey924090 The word pharmacy is derived from the Greek word Pharmakon, meaning medicine or drug. In other term, Pharmacy may defined as the art and science of preparing (manufacturing) and dispensing of drugs prepared by the natural and synthetic sources and using for the treatment as well as prevention of diseases. In general sense, it is the place where medicine or drugs are sold. Pharmacy is a health profession that links health science with chemical science and aims to ensure the safe and effective use of pharmaceutical drugs. It includes the collection, identification, synthesis, purification, isolation and quality control of medical substance or pharmaceutical products. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/introductiontopharmacypharmaceutics-231202051409-65414bfa-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> The word pharmacy is derived from the Greek word Pharmakon, meaning medicine or drug. In other term, Pharmacy may defined as the art and science of preparing (manufacturing) and dispensing of drugs prepared by the natural and synthetic sources and using for the treatment as well as prevention of diseases. In general sense, it is the place where medicine or drugs are sold. Pharmacy is a health profession that links health science with chemical science and aims to ensure the safe and effective use of pharmaceutical drugs. It includes the collection, identification, synthesis, purification, isolation and quality control of medical substance or pharmaceutical products.
IntroductiontoPharmacyPharmaceutics.pptx from Prachi Pandey
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https://cdn.slidesharecdn.com/profile-photo-prachipandey924090-48x48.jpg?cb=1731940366 Hi everyone, I would like to tell that my B. Pharm from Amity University Lucknow, India and M. Pharm (Pharmaceutics) from NIMS University Jaipur Rajasthan, India. I have recently published 20 articles and 2 research papers along with 3 books that are active on Amazon,Flipkart and e-educational platforms. www.linkedin.com/in/prachi-pandey-0a0984217/ https://cdn.slidesharecdn.com/ss_thumbnails/niosomeannon-ionicsurfactantvesicles-240320165600-592c4e33-thumbnail.jpg?width=320&height=320&fit=bounds slideshow/niosome-an-nonionic-surfactant-vesiclespptx/266889926 Niosome An Non-Ionic S... https://cdn.slidesharecdn.com/ss_thumbnails/niosomesformulationandevaluation-240303044608-ca334496-thumbnail.jpg?width=320&height=320&fit=bounds slideshow/niosomes-formulation-and-evaluationpptx-1777/266599437 Niosomes (Formulation ... https://cdn.slidesharecdn.com/ss_thumbnails/analgesicniosomes-240126132130-40f8f338-thumbnail.jpg?width=320&height=320&fit=bounds slideshow/advancement-and-characteristics-of-nonionic-surfactant-vesicle-niosome-and-their-application-for-analgesics/265826799 ю...