�ݺ�ߣshows by User: simonsilvan

�ݺ�ߣshows by User: simonsilvan / http://www.slideshare.net/images/logo.gif �ݺ�ߣshows by User: simonsilvan / Fri, 27 Sep 2019 15:56:16 GMT �ݺ�ߣShare feed for �ݺ�ߣshows by User: simonsilvan Single nucleotide polymorphism /slideshow/single-nucleotide-polymorphism-176811844/176811844 singlenucleotidepolymorphism-190927155616
Single Nucleotide Polymorphism (SNP) Polymorphism is a generic term that means 'many shapes‘. It is the ability to appsear in different form . A single nucleotide polymorphism (SNP) is a DNA sequence variation occurring when a single nucleotide - A, T, C, or G - in the genome differs between members of a species (or between paired chromosomes in an individual). For example, two sequenced DNA fragments from different individuals, AAGCCTA to AAGCTTA, contain a difference in a single nucleotide. For a variation to be considered a SNP, it must occur in at least 1% of the population. CHARACTERISTICS OF SNP • In human beings, 99.9 percent bases are same. • Remaining 0.1 percent makes a person unique. • Different attributes / characteristics / traits • How a person looks, diseases he or she develops. These variations can be:  Harmless (change in phenotype)  Harmful (diabetes, cancer, heart disease, Huntington's disease, and hemophilia )  Latent (variations found in coding and regulatory regions, are not harmful on their own, and the change in each gene only becomes apparent under certain conditions e.g. susceptibility to lung cancer) TYPES OF SNP NON-CODING REGION A segment of DNA that does comprise a gene and thus does not code for a protein . CODING REGION Regions of DNA/RNA sequences that code for proteins Synonymous A SNP in which both forms lead to the same polypeptide sequence is termed synonymous (sometimes called a silent mutation). Non synonymous If a different polypeptide sequence is produced they are non synonymous . A non synonymous change may either be missense or nonsense, where a missense change results in a different amino acid, while a nonsense change results in a premature stop codon. SNP Applications • Gene discovery and mapping • Association-based candidate polymorphism testing • Diagnostics/risk profiling • Response prediction • Homogeneity testing/study design • Gene function identification ]]>
Single Nucleotide Polymorphism (SNP) Polymorphism is a generic term that means 'many shapes‘. It is the ability to appsear in different form . A single nucleotide polymorphism (SNP) is a DNA sequence variation occurring when a single nucleotide - A, T, C, or G - in the genome differs between members of a species (or between paired chromosomes in an individual). For example, two sequenced DNA fragments from different individuals, AAGCCTA to AAGCTTA, contain a difference in a single nucleotide. For a variation to be considered a SNP, it must occur in at least 1% of the population. CHARACTERISTICS OF SNP • In human beings, 99.9 percent bases are same. • Remaining 0.1 percent makes a person unique. • Different attributes / characteristics / traits • How a person looks, diseases he or she develops. These variations can be:  Harmless (change in phenotype)  Harmful (diabetes, cancer, heart disease, Huntington's disease, and hemophilia )  Latent (variations found in coding and regulatory regions, are not harmful on their own, and the change in each gene only becomes apparent under certain conditions e.g. susceptibility to lung cancer) TYPES OF SNP NON-CODING REGION A segment of DNA that does comprise a gene and thus does not code for a protein . CODING REGION Regions of DNA/RNA sequences that code for proteins Synonymous A SNP in which both forms lead to the same polypeptide sequence is termed synonymous (sometimes called a silent mutation). Non synonymous If a different polypeptide sequence is produced they are non synonymous . A non synonymous change may either be missense or nonsense, where a missense change results in a different amino acid, while a nonsense change results in a premature stop codon. SNP Applications • Gene discovery and mapping • Association-based candidate polymorphism testing • Diagnostics/risk profiling • Response prediction • Homogeneity testing/study design • Gene function identification ]]> Fri, 27 Sep 2019 15:56:16 GMT /slideshow/single-nucleotide-polymorphism-176811844/176811844 simonsilvan@slideshare.net(simonsilvan) Single nucleotide polymorphism simonsilvan Single Nucleotide Polymorphism (SNP) Polymorphism is a generic term that means 'many shapes‘. It is the ability to appsear in different form . A single nucleotide polymorphism (SNP) is a DNA sequence variation occurring when a single nucleotide - A, T, C, or G - in the genome differs between members of a species (or between paired chromosomes in an individual). For example, two sequenced DNA fragments from different individuals, AAGCCTA to AAGCTTA, contain a difference in a single nucleotide. For a variation to be considered a SNP, it must occur in at least 1% of the population. CHARACTERISTICS OF SNP • In human beings, 99.9 percent bases are same. • Remaining 0.1 percent makes a person unique. • Different attributes / characteristics / traits • How a person looks, diseases he or she develops. These variations can be:  Harmless (change in phenotype)  Harmful (diabetes, cancer, heart disease, Huntington's disease, and hemophilia )  Latent (variations found in coding and regulatory regions, are not harmful on their own, and the change in each gene only becomes apparent under certain conditions e.g. susceptibility to lung cancer) TYPES OF SNP NON-CODING REGION A segment of DNA that does comprise a gene and thus does not code for a protein . CODING REGION Regions of DNA/RNA sequences that code for proteins Synonymous A SNP in which both forms lead to the same polypeptide sequence is termed synonymous (sometimes called a silent mutation). Non synonymous If a different polypeptide sequence is produced they are non synonymous . A non synonymous change may either be missense or nonsense, where a missense change results in a different amino acid, while a nonsense change results in a premature stop codon. SNP Applications • Gene discovery and mapping • Association-based candidate polymorphism testing • Diagnostics/risk profiling • Response prediction • Homogeneity testing/study design • Gene function identification <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/singlenucleotidepolymorphism-190927155616-thumbnail.jpg?width=120&height=120&fit=bounds" /><br> Single Nucleotide Polymorphism (SNP) Polymorphism is a generic term that means 'many shapes‘. It is the ability to appsear in different form . A single nucleotide polymorphism (SNP) is a DNA sequence variation occurring when a single nucleotide - A, T, C, or G - in the genome differs between members of a species (or between paired chromosomes in an individual). For example, two sequenced DNA fragments from different individuals, AAGCCTA to AAGCTTA, contain a difference in a single nucleotide. For a variation to be considered a SNP, it must occur in at least 1% of the population. CHARACTERISTICS OF SNP • In human beings, 99.9 percent bases are same. • Remaining 0.1 percent makes a person unique. • Different attributes / characteristics / traits • How a person looks, diseases he or she develops. These variations can be:  Harmless (change in phenotype)  Harmful (diabetes, cancer, heart disease, Huntington's disease, and hemophilia )  Latent (variations found in coding and regulatory regions, are not harmful on their own, and the change in each gene only becomes apparent under certain conditions e.g. susceptibility to lung cancer) TYPES OF SNP NON-CODING REGION A segment of DNA that does comprise a gene and thus does not code for a protein . CODING REGION Regions of DNA/RNA sequences that code for proteins Synonymous A SNP in which both forms lead to the same polypeptide sequence is termed synonymous (sometimes called a silent mutation). Non synonymous If a different polypeptide sequence is produced they are non synonymous . A non synonymous change may either be missense or nonsense, where a missense change results in a different amino acid, while a nonsense change results in a premature stop codon. SNP Applications • Gene discovery and mapping • Association-based candidate polymorphism testing • Diagnostics/risk profiling • Response prediction • Homogeneity testing/study design • Gene function identification

Single nucleotide polymorphism from Simon Silvan

]]> 257 0 https://cdn.slidesharecdn.com/ss_thumbnails/singlenucleotidepolymorphism-190927155616-thumbnail.jpg?width=120&height=120&fit=bounds document Black http://activitystrea.ms/schema/1.0/post

http://activitystrea.ms/schema/1.0/posted

0 Structure of chromosome /slideshow/structure-of-chromosome/176808065 structureofchromosome-190927154433
to understand the structure chromosome and function]]>
to understand the structure chromosome and function]]> Fri, 27 Sep 2019 15:44:33 GMT /slideshow/structure-of-chromosome/176808065 simonsilvan@slideshare.net(simonsilvan) Structure of chromosome simonsilvan to understand the structure chromosome and function <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/structureofchromosome-190927154433-thumbnail.jpg?width=120&height=120&fit=bounds" /><br> to understand the structure chromosome and function

Structure of chromosome from Simon Silvan

]]> 1992 0 https://cdn.slidesharecdn.com/ss_thumbnails/structureofchromosome-190927154433-thumbnail.jpg?width=120&height=120&fit=bounds document Black http://activitystrea.ms/schema/1.0/post

http://activitystrea.ms/schema/1.0/posted

0 https://cdn.slidesharecdn.com/profile-photo-simonsilvan-48x48.jpg?cb=1708955047 i am a good . https://cdn.slidesharecdn.com/ss_thumbnails/singlenucleotidepolymorphism-190927155616-thumbnail.jpg?width=320&height=320&fit=bounds slideshow/single-nucleotide-polymorphism-176811844/176811844 Single nucleotide poly... https://cdn.slidesharecdn.com/ss_thumbnails/structureofchromosome-190927154433-thumbnail.jpg?width=320&height=320&fit=bounds slideshow/structure-of-chromosome/176808065 Structure of chromosome