Presentation slides shows the problems and health disorders due to Vitamin A deficiency, Sources, treatment and diagnostic method. Also about the factor affecting the utilization of Vitamin A.
2. Introduction:
Vitamin A is a fat soluble vitamin that is also a
powerful antioxidant.
Vitamin A is an essential nutrient requirement
for vital functions in man and animals.
Vitamin A plays a critical role in maintaining
healthy vision, neurological function, healthy
skin, and more.
3. Prolonged inadequate intake of Vitamin causes the
apparent signs like
Anorexia
Weight loss
Keratinization
Reduced secretion from mucus secreting glands
Nervous disorder
Reproductive inefficiency
Impairment of visions
Reduced resistance to infection and ultimate
death.
4. Sources:
Vitamin A is found in two primary forms:
active Vitamin A and beta carotene.
Some of the best sources of Vitamin A include
eggs, milk, liver, carrots, yellow or orange
vegetables such as squash, spinach, and other
leafy green vegetables.
6. Factors affecting the utilization of
Vitamin-A
Environmental temperature
Ration
Inclement weather
Hypothyroidism
Hypophosphatemia
Cathartic drug (paraffin)
Nitrate and Nitrites
Disease
Carotinase
Vitamin E
7. Deficiency:
1. Poor growth:
Essential for growth of tissue.
Deficient diet causes poor appetite and
emaciation in growing animals.
8. 2. Vision:
There is impairment of vision.
Change in eye may be primary or secondary.
A. Primary:
a) Conjuctival Xerosis: Dryness, Loss of transparency, thickening,
wrinkling, pigmentation, accumulation of debris.
b) Biots spot: Appears as small silver grey raised plague of
conjunctiva.
c) Corneal xerosis: Cornea turn hazy due to cellular infiltration
and assume bluish milky appearance.
d) Corneal ulceration: There is denudation of epithelial surface.
e) Keratomalacia : Softening of cornea due to coagulative
necrosis.
9. B) Secondary:
a) Night blindness: Less supply of vitamin A to
the rod cells of the retina causes an
impairment of dark adaption.
b) Xeropthalmia: Dry eye.
c) Corneal Scar: Healed of corneal ulcer,
keratomalacia may be taken over as scar.
10. 3. Compression of brain
4. Neurological disorder: Incoordination and
paralysis of skeletal muscles.
5. Bone formation: Decrease osteoblastic
activity and poor osteogenesis
6. Degenerative changes in alimentary,
respiratory and urinary tract epithelium.
7. Reproduction: Degenerative changes in testis
leading to impairment of spermatogenesis,
oogenesis in female is also impaired.
Reproduction failure in both sex.
11. Diagnosis:
a) History of diet
b) Clinical signs
c) Plasma and liver vitamin level can be
determined by
Ultraviolet absorption spectrophotometry
Fluorimetry
Colorimetry