1 of 6
Download to read offline
Ad
Recommended
ADULT RESPIRATORY DISTRESS SYNDROME (ARDS)
ADULT RESPIRATORY DISTRESS SYNDROME (ARDS)Rajendran Surendran
油
Non-cardiogenic pulmonary edema, also known as acute respiratory distress syndrome (ARDS), is characterized by severe arterial hypoxemia, bilateral alveolar infiltrates on chest imaging, and a normal left atrial pressure. It results from increased vascular permeability in the lungs leading to fluid accumulation in the alveoli and impaired gas exchange. The underlying pathophysiology involves diffuse damage to the alveolar-capillary membrane by various insults such as sepsis, infection, or injury. This disrupts the normal barrier function and leads to flooding of the lungs with protein-rich fluid.Ards
ArdsSmritikana Pan
油
ARDS is characterized by acute lung injury and hypoxemia. The document discusses definitions, pathophysiology, and treatment strategies for ARDS. Regarding treatment, the key principles are providing adequate gas exchange while minimizing ventilator-induced lung injury through gentle ventilation with low tidal volumes, optimal PEEP, and permissive hypercapnia. Additional strategies like prone positioning and inhaled nitric oxide may improve oxygenation, but their effects on long-term outcomes are unclear. Overall, ARDS carries a high mortality rate due to its association with multi-organ dysfunction syndrome.Rob Mac Sweeney's FFICM Hot Topics Talk March 2016
Rob Mac Sweeney's FFICM Hot Topics Talk March 2016robmacsweeney
油
The document summarizes major research studies and clinical trials from 2012 to 2016, focusing on critical care and emergency medicine topics such as sepsis, fluid resuscitation, and nutritional support. Each study highlights findings on patient outcomes, mortality rates, and treatment efficacy, noting contrasts between various interventions like paracetamol use, resuscitation fluids, and ventilation strategies. The document serves as a comprehensive review of evolving practices and guidelines in intensive care based on recent evidence.Acute Lung Injury & ARDS
Acute Lung Injury & ARDScairo1957
油
The document provides an overview of acute lung injury (ALI) and acute respiratory distress syndrome (ARDS), including definitions, risk factors, pathogenesis, management approaches, and results from major clinical trials. It discusses how lower tidal volume ventilation as tested in the ARDS Network trial was the first intervention shown to improve survival for patients with ALI/ARDS.ARDS: An Evidence-based Update. By Mac Sweeney.
ARDS: An Evidence-based Update. By Mac Sweeney.SMACC Conference
油
The document presents an evidence-based update on Acute Respiratory Distress Syndrome (ARDS) highlighting diagnostic challenges, limited treatment options, and the need for critical evaluation of existing research. It discusses various therapeutic interventions, their efficacy, and the complexity of identifying the underlying causes of ARDS. The document concludes by questioning the utility of ARDS as a clinical syndrome and emphasizes the necessity for improved identification of alveolar injury in future studies.Acute Respiratory Distress Syndrome
Acute Respiratory Distress SyndromeMekelle Universty
油
This document provides an overview of acute respiratory distress syndrome (ARDS). It defines ARDS and describes its three phases: exudative, proliferative, and fibrotic. ARDS is caused by lung injury from medical or surgical disorders and results in hypoxemia. Treatment focuses on treating the underlying cause, mechanical ventilation with low tidal volumes to prevent further lung injury, and maintaining a normal fluid balance to reduce pulmonary edema. While various adjunctive therapies have been investigated, supportive care remains the primary treatment approach.Splenomegaly with answers
Splenomegaly with answersmccrad
油
There is an old splenic infarct seen as an area of low attenuation on CT scan without contrast. This area of low attenuation remains poorly visualized following intravenous contrast administration, consistent with an old splenic infarct. The splenic infarct appears as an area of low attenuation both before and after contrast administration.Ct sah answer
Ct sah answermccrad
油
The document describes a patient with enlarged ventricles due to hydrocephalus and a small aneurysm on a branch of the right middle cerebral artery. A 4x2mm saccular aneurysm was found on the M1 branch of the right middle cerebral artery in addition to prominent ventricles caused by hydrocephalus.Case 1 answer
Case 1 answermccrad
油
This document discusses portal venous gas seen on chest x-rays. Portal venous gas occurs when air enters the portal vein, usually due to necrosis of the stomach or gut wall, and is a very serious sign. It needs to be differentiated from pneumobilia, where air is in the bile ducts. Portal venous gas has a peripheral distribution of air in the liver, while pneumobilia is more centrally located. The document also mentions pneumatosis intestinalis, where air is found in the gut wall, which can indicate necrotizing enterocolitis or gut infarction.5-Lift Analysis in ergonomics focuses on evaluating the safety and efficienc...
5-Lift Analysis in ergonomics focuses on evaluating the safety and efficienc...Bolan University of Medical and Health Sciences ,Quetta
油
Lift Analysis in ergonomics focuses on evaluating the safety and efficiency of manual lifting tasks in the workplace. It involves assessing the physical demands placed on the human body during lifting activities to prevent musculoskeletal disorders (MSDs), particularly lower back injuriesState of the Art LVAD Care: What Does the Year 2025 Bring?
State of the Art LVAD Care: What Does the Year 2025 Bring?Duke Heart
油
Elizabeth Volz, MD
University of North Carolina-Chapel HillGrowth hormone by Dr Kondam AmbareeshaGoud
Growth hormone by Dr Kondam AmbareeshaGoudDr K Ambareesha Goud PhD
油
Growth hormone (GH) secretion from anterior pituitary is regulated by the hypothalamus and the mediators of GH actions. Major regulatory factors include GH releasing hormone (GHRH), somatostatin (SRIF), GH releasing peptide (ghrerin) and insulin-like growth factor (IGF-I).Ratricharya according to ayurveda along with day and night pattern in various...
Ratricharya according to ayurveda along with day and night pattern in various...DR DHARMENDRA BINJHWAR
油
This slide are more importents for ayurveda students and teachers because i have mentioned in this slide night time routine in ayurveda the ancient science of India along with day and night pattern in various counteries within in one ppt. thanks for watching i will be greatful for your suggestion and feedback... please like share and suppourtEvolution of Diagnostic and Treatment Options in ATTR Cardiac Amyloidosis
Evolution of Diagnostic and Treatment Options in ATTR Cardiac AmyloidosisDuke Heart
油
Michel Khouri, MD
Duke UniversityPalliative Care for Patients with Heart Failure
Palliative Care for Patients with Heart FailureDuke Heart
油
Vishal Rao, MD, MPH
Medical University of South CarolinaCOUGH AND THIER DRUGS AND MODE OF ACTION.pptx
COUGH AND THIER DRUGS AND MODE OF ACTION.pptxPackialakshmiP
油
COUGH AND THIER DRUGS AND MODE OF ACTIONUpdates_in Head__Neck TNM staging- 9th edition.pptx
Updates_in Head__Neck TNM staging- 9th edition.pptxDr. Maroti Wadewale
油
The Union for International Cancer Control (UICC) and the American Joint Committee on Cancer (AJCC) collaborate closely to produce the globally recognized TNM Classification of Malignant Tumours. Therefore, when discussing the "9th edition of UICC head and neck staging," it's largely in alignment with the updates introduced by the AJCC's Version 9. The UICC's TNM Core Committee finalized the 9th edition of the TNM Classification, with publication anticipated in August 2025.
The key updates for head and neck cancers in the 9th edition (or Version 9) reflect an ongoing effort to improve prognostic accuracy and align staging with contemporary clinical understanding and treatment outcomes. Here are the significant changes, particularly those relevant to head and neck:
* Emphasis on Personalized Care and Prognostic Refinements: The 9th edition reflects a greater focus on personalized care, incorporating refinements that aim to better predict patient outcomes.
* Revised Criteria for Specific Head and Neck Cancers:
* Nasopharyngeal Carcinoma (NPC): This site has seen substantial revisions, as highlighted in the previous response on AJCC updates. Key changes include:
* More precise definition of T3 disease (unequivocal evidence of bone involvement).
* Introduction of advanced radiologic extranodal extension (ENE) as an N3 criterion. This acknowledges the prognostic impact of ENE seen on imaging.
* Subclassification of M1 disease into M1a (3 or fewer metastatic lesions) and M1b (more than 3 lesions) to better stratify prognosis in metastatic settings.
* Redefined Stage Groups for NPC, with T1-2N0-1 now often falling into Stage I, and Stage IV being exclusively for metastatic disease, further subdivided by the M1a/M1b categories.
* Salivary Gland Cancers: Revised criteria based on updated imaging and anatomical features are being incorporated.
* HPV-Related Oropharyngeal Cancers: New staging is introduced for HPV-associated oropharyngeal cancers to better reflect their distinct biological behavior and prognosis, which is generally more favorable than HPV-negative oropharyngeal cancers. This often involves specific considerations for nodal burden.
* Integration of Imaging and Anatomical Features: The updates are grounded in recent evidence, incorporating insights from advanced imaging techniques and a deeper understanding of anatomical spread.
* International Collaboration: These updates are the result of collaborative efforts between the AJCC and UICC, involving input from cancer registries, clinical outcomes data, and disease-specific experts worldwide. The goal is to provide a unified and globally applicable staging system.
* Dynamic Update Process: Similar to the AJCC's shift from "Editions" to "Versions" for specific sites, the UICC is also exploring more flexible ways to share future TNM updates.
In essence, the 9th edition of the UICC staging system for head and neck cancers, particularly in areas like NPC and HPVMore Related Content
More from mccrad (11)
Splenomegaly with answers
Splenomegaly with answersmccrad
油
There is an old splenic infarct seen as an area of low attenuation on CT scan without contrast. This area of low attenuation remains poorly visualized following intravenous contrast administration, consistent with an old splenic infarct. The splenic infarct appears as an area of low attenuation both before and after contrast administration.Ct sah answer
Ct sah answermccrad
油
The document describes a patient with enlarged ventricles due to hydrocephalus and a small aneurysm on a branch of the right middle cerebral artery. A 4x2mm saccular aneurysm was found on the M1 branch of the right middle cerebral artery in addition to prominent ventricles caused by hydrocephalus.Case 1 answer
Case 1 answermccrad
油
This document discusses portal venous gas seen on chest x-rays. Portal venous gas occurs when air enters the portal vein, usually due to necrosis of the stomach or gut wall, and is a very serious sign. It needs to be differentiated from pneumobilia, where air is in the bile ducts. Portal venous gas has a peripheral distribution of air in the liver, while pneumobilia is more centrally located. The document also mentions pneumatosis intestinalis, where air is found in the gut wall, which can indicate necrotizing enterocolitis or gut infarction.Recently uploaded (20)
5-Lift Analysis in ergonomics focuses on evaluating the safety and efficienc...
5-Lift Analysis in ergonomics focuses on evaluating the safety and efficienc...Bolan University of Medical and Health Sciences ,Quetta
油
Lift Analysis in ergonomics focuses on evaluating the safety and efficiency of manual lifting tasks in the workplace. It involves assessing the physical demands placed on the human body during lifting activities to prevent musculoskeletal disorders (MSDs), particularly lower back injuriesState of the Art LVAD Care: What Does the Year 2025 Bring?
State of the Art LVAD Care: What Does the Year 2025 Bring?Duke Heart
油
Elizabeth Volz, MD
University of North Carolina-Chapel HillGrowth hormone by Dr Kondam AmbareeshaGoud
Growth hormone by Dr Kondam AmbareeshaGoudDr K Ambareesha Goud PhD
油
Growth hormone (GH) secretion from anterior pituitary is regulated by the hypothalamus and the mediators of GH actions. Major regulatory factors include GH releasing hormone (GHRH), somatostatin (SRIF), GH releasing peptide (ghrerin) and insulin-like growth factor (IGF-I).Ratricharya according to ayurveda along with day and night pattern in various...
Ratricharya according to ayurveda along with day and night pattern in various...DR DHARMENDRA BINJHWAR
油
This slide are more importents for ayurveda students and teachers because i have mentioned in this slide night time routine in ayurveda the ancient science of India along with day and night pattern in various counteries within in one ppt. thanks for watching i will be greatful for your suggestion and feedback... please like share and suppourtEvolution of Diagnostic and Treatment Options in ATTR Cardiac Amyloidosis
Evolution of Diagnostic and Treatment Options in ATTR Cardiac AmyloidosisDuke Heart
油
Michel Khouri, MD
Duke UniversityPalliative Care for Patients with Heart Failure
Palliative Care for Patients with Heart FailureDuke Heart
油
Vishal Rao, MD, MPH
Medical University of South CarolinaCOUGH AND THIER DRUGS AND MODE OF ACTION.pptx
COUGH AND THIER DRUGS AND MODE OF ACTION.pptxPackialakshmiP
油
COUGH AND THIER DRUGS AND MODE OF ACTIONUpdates_in Head__Neck TNM staging- 9th edition.pptx
Updates_in Head__Neck TNM staging- 9th edition.pptxDr. Maroti Wadewale
油
The Union for International Cancer Control (UICC) and the American Joint Committee on Cancer (AJCC) collaborate closely to produce the globally recognized TNM Classification of Malignant Tumours. Therefore, when discussing the "9th edition of UICC head and neck staging," it's largely in alignment with the updates introduced by the AJCC's Version 9. The UICC's TNM Core Committee finalized the 9th edition of the TNM Classification, with publication anticipated in August 2025.
The key updates for head and neck cancers in the 9th edition (or Version 9) reflect an ongoing effort to improve prognostic accuracy and align staging with contemporary clinical understanding and treatment outcomes. Here are the significant changes, particularly those relevant to head and neck:
* Emphasis on Personalized Care and Prognostic Refinements: The 9th edition reflects a greater focus on personalized care, incorporating refinements that aim to better predict patient outcomes.
* Revised Criteria for Specific Head and Neck Cancers:
* Nasopharyngeal Carcinoma (NPC): This site has seen substantial revisions, as highlighted in the previous response on AJCC updates. Key changes include:
* More precise definition of T3 disease (unequivocal evidence of bone involvement).
* Introduction of advanced radiologic extranodal extension (ENE) as an N3 criterion. This acknowledges the prognostic impact of ENE seen on imaging.
* Subclassification of M1 disease into M1a (3 or fewer metastatic lesions) and M1b (more than 3 lesions) to better stratify prognosis in metastatic settings.
* Redefined Stage Groups for NPC, with T1-2N0-1 now often falling into Stage I, and Stage IV being exclusively for metastatic disease, further subdivided by the M1a/M1b categories.
* Salivary Gland Cancers: Revised criteria based on updated imaging and anatomical features are being incorporated.
* HPV-Related Oropharyngeal Cancers: New staging is introduced for HPV-associated oropharyngeal cancers to better reflect their distinct biological behavior and prognosis, which is generally more favorable than HPV-negative oropharyngeal cancers. This often involves specific considerations for nodal burden.
* Integration of Imaging and Anatomical Features: The updates are grounded in recent evidence, incorporating insights from advanced imaging techniques and a deeper understanding of anatomical spread.
* International Collaboration: These updates are the result of collaborative efforts between the AJCC and UICC, involving input from cancer registries, clinical outcomes data, and disease-specific experts worldwide. The goal is to provide a unified and globally applicable staging system.
* Dynamic Update Process: Similar to the AJCC's shift from "Editions" to "Versions" for specific sites, the UICC is also exploring more flexible ways to share future TNM updates.
In essence, the 9th edition of the UICC staging system for head and neck cancers, particularly in areas like NPC and HPVGAIT in Biomechanics along with abnormal gait
GAIT in Biomechanics along with abnormal gaitNerusu sai priyanka
油
Gait , ab normal gait,normal biomechanics,pathomechanics of gait,unilateral stance,factors affectoing gait REFRAMING OF EXPERTISE AND INFORMATION IN HEALTH
REFRAMING OF EXPERTISE AND INFORMATION IN HEALTHTina Purnat
油
A talk I gave at CDIC 2025 on how information and expertise in health are being reframed and how this demands change from public health.General Pharmacology
General Pharmacology Umanath Singh Autonomous State Medical College, Jaunpur
油
This is ppt of general pharmacology and its aspectMultidisciplinary Strategies in GDMT Implementation
Multidisciplinary Strategies in GDMT ImplementationDuke Heart
油
Aferdita Spahillari, MD
Duke University Why Dental Implants Fail Quality Care for Your Smile
Why Dental Implants Fail Quality Care for Your SmileReveal Dental
油
Explore the critical factors behind dental implant failures and discover essential tips for ensuring lasting, quality care that enhances your smile's health and longevity.Devices in the Management of Acute Heart Failure (or) Cardiogenic Shock
Devices in the Management of Acute Heart Failure (or) Cardiogenic ShockDuke Heart
油
M. Imran Aslam, MD
Duke University 5-Lift Analysis in ergonomics focuses on evaluating the safety and efficienc...
5-Lift Analysis in ergonomics focuses on evaluating the safety and efficienc...Bolan University of Medical and Health Sciences ,Quetta
油
Ratricharya according to ayurveda along with day and night pattern in various...
Ratricharya according to ayurveda along with day and night pattern in various...DR DHARMENDRA BINJHWAR
油
Ad