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H. pyloriAssociated Ulcers
NSAID-Induced Ulcers
Stress-Related Mucosal Disease (SRMD)
ZollingerEllison Syndrome (gastrinoma-related)
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1. Acid Suppression Therapy
Class Examples Mechanism
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2. Mucosal Protective Agents
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Mucosal Coating Agents Sucralfate Forms protective barrier over ulcer site
Bismuth Compounds Bismuth subsalicylate Antimicrobial, mucosal protective, and anti-inflammatory
3. Eradication Therapy (for H. pylori)
Combination of:
PPI + Two Antibiotics (e.g., amoxicillin + clarithromycin OR metronidazole + tetracycline)
Duration: 714 days depending on local guidelines
See BNF regimens above for detailed protocols
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Non-Pharmacologic Measures
Avoid NSAIDs, smoking, alcohol, and spicy foods
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Endoscopic therapy in case of bleeding or perforation
Surgical Indications (rarely needed)
Perforated ulcer
Gastric outlet obstruction
Refractory ulcers not responding to medical therapy
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Yoga postures are commonly depicted in ancient paintings, carvings, and sculptures in almost all civilizations and religions, thus Yoga cant be described as an act of Hinduism. It originated long before any religion on Earth, with the emergence of life on the Planet. All yoga poses are natural, and what is not natural is not yoga; it is油Viyoga.
Besides Vedic Yoga, Hatha, Vinyasa, Ashtanga, Iyengar, Yin, Restorative, Kundalini, Bikram, Sahaj, and Power yoga are some popular types.
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Open PPT for detail description: Peptic Ulcer Disease (PUD)
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Classification of Peptic Ulcers
Based on Location
Gastric Ulcers Occur in the stomach lining.
Duodenal Ulcers Occur in the first part of the small intestine (duodenum).
Based on Etiology
H. pyloriAssociated Ulcers
NSAID-Induced Ulcers
Stress-Related Mucosal Disease (SRMD)
ZollingerEllison Syndrome (gastrinoma-related)
Cushings Ulcer (due to intracranial injury)
Curlings Ulcer (seen in burn patients)
Pharmacological Management
1. Acid Suppression Therapy
Class Examples Mechanism
Proton Pump Inhibitors (PPIs) Omeprazole, Pantoprazole Irreversibly inhibit H+/K+ ATPase pump
H2-Receptor Antagonists Ranitidine, Famotidine Block histamine-mediated gastric acid secretion
2. Mucosal Protective Agents
Class Examples Mechanism
Prostaglandin Analogues Misoprostol Increases mucus & bicarbonate; decreases acid; protects mucosa
Mucosal Coating Agents Sucralfate Forms protective barrier over ulcer site
Bismuth Compounds Bismuth subsalicylate Antimicrobial, mucosal protective, and anti-inflammatory
3. Eradication Therapy (for H. pylori)
Combination of:
PPI + Two Antibiotics (e.g., amoxicillin + clarithromycin OR metronidazole + tetracycline)
Duration: 714 days depending on local guidelines
See BNF regimens above for detailed protocols
4. Cytoprotective/Adjunctive Agents
Class Examples Role in PUD
Somatostatin Analogues Octreotide Used in bleeding ulcers; reduces splanchnic blood flow and gastric secretions
Antacids Magnesium hydroxide, Aluminium hydroxide Neutralize gastric acid; provide symptomatic relief
Non-Pharmacologic Measures
Avoid NSAIDs, smoking, alcohol, and spicy foods
Small, frequent meals in symptomatic patients
Stress reduction
Endoscopic therapy in case of bleeding or perforation
Surgical Indications (rarely needed)
Perforated ulcer
Gastric outlet obstruction
Refractory ulcers not responding to medical therapy
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Besides Vedic Yoga, Hatha, Vinyasa, Ashtanga, Iyengar, Yin, Restorative, Kundalini, Bikram, Sahaj, and Power yoga are some popular types.
Vinyasa油Yoga is the closest form to Vedic Yoga; it is known for its flowing movements, not very rigorous, not too much straining, actions flow with the breath.
Though all yoga may lead to meditation (Dhyan) for your inner upliftment, it is not the same as described in Hinduism for self-liberation.
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The 2024 social media marketing trends report highlights significant shifts influenced by generative AI, including the emergence of personalized content, the rise of virtual influencers, and a stronger focus on user-generated content. Insights were gathered from 33 experts across 23 leading independent agencies, providing a perspective that emphasizes creativity and authenticity in marketing strategies. Key trends also include the blending of B2B and B2C approaches, reflecting changes in consumer behavior and the evolving landscape of social media engagement.Trends In Paid Search: Navigating The Digital Landscape In 2024
Trends In Paid Search: Navigating The Digital Landscape In 2024Search Engine Journal
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The document discusses trends in paid search for 2024, highlighting changes in user behavior, the implications for financial services, and privacy challenges. It emphasizes the importance of adapting search strategies, utilizing AI-driven tools like performance max and smart bidding, and leveraging first-party data for better marketing efficacy. Key takeaways include holistic SEO and SEM approaches, monitoring shifting user intents, and the need for continuous performance evaluation.5 Public speaking tips from TED - Visualized summary
5 Public speaking tips from TED - Visualized summarySpeakerHub
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The document outlines five public speaking tips from Chris Anderson, TED Talks curator, emphasizing the importance of eye contact, vulnerability, humor, humility, and storytelling. These skills are presented as essential for engaging audiences effectively and are increasingly valuable in today's economy. The article posits that mastering these techniques can enhance speakers' ability to communicate ideas powerfully.ChatGPT and the Future of Work - Clark Boyd
ChatGPT and the Future of Work - Clark Boyd Clark Boyd
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The document provides an overview of generative AI, particularly focusing on ChatGPT and its implications for business and the job market. It discusses the rapid growth of generative AI, its applications in marketing, and the skills needed for the AI era while addressing potential job displacement and the need for adaptation. The agenda includes a Q&A session and emphasizes rethinking work in collaboration with AI technology.Getting into the tech field. what next
Getting into the tech field. what next Tessa Mero
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The document provides career advice for getting into the tech field, including:
- Doing projects and internships in college to build a portfolio.
- Learning about different roles and technologies through industry research.
- Contributing to open source projects to build experience and network.
- Developing a personal brand through a website and social media presence.
- Networking through events, communities, and finding a mentor.
- Practicing interviews through mock interviews and whiteboarding coding questions.Google's Just Not That Into You: Understanding Core Updates & Search Intent
Google's Just Not That Into You: Understanding Core Updates & Search IntentLily Ray
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1. Core updates from Google periodically change how its algorithms assess and rank websites and pages. This can impact rankings through shifts in user intent, site quality issues being caught up to, world events influencing queries, and overhauls to search like the E-A-T framework.
2. There are many possible user intents beyond just transactional, navigational and informational. Identifying intent shifts is important during core updates. Sites may need to optimize for new intents through different content types and sections.
3. Responding effectively to core updates requires analyzing "before and after" data to understand changes, identifying new intents or page types, and ensuring content matches appropriate intents across video, images, knowledge graphs and more.How to have difficult conversations
How to have difficult conversations Rajiv Jayarajah, MAppComm, ACC
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The document provides essential tips on how to handle difficult conversations in a workplace setting, emphasizing the importance of preparation, environment, and timing. It highlights that many employees dread such conversations, often leading to avoidance and worsening situations. Ultimately, the guide aims to promote positive outcomes while maintaining professional relationships.Introduction to Data Science
Introduction to Data ScienceChristy Abraham Joy
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The document discusses the rise and importance of data science and machine learning, highlighting the growing demand for data scientists and the challenges they face. It explains machine learning concepts such as supervised and unsupervised learning, along with various real-world applications and the necessary steps involved in a machine learning workflow. Additionally, the document emphasizes the iterative process of model improvement and feature engineering used to enhance machine learning outcomes.Time Management & Productivity - Best Practices
Time Management & Productivity - Best PracticesVit Horky
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The document outlines best practices for time management and productivity, focusing on effective meeting habits, structured work blocks, and the importance of reflection and goal setting. It emphasizes the need for proper planning, the use of appropriate tools, and prioritizing tasks to enhance both personal and team efficiency. Additionally, personal anecdotes and strategies are shared to encourage a positive mindset and enjoyment in achieving work-related goals.The six step guide to practical project management
The six step guide to practical project managementMindGenius
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The document outlines a simplified six-step guide to project management designed for individuals lacking formal training. It emphasizes the importance of understanding project objectives, gathering stakeholder requirements, defining project scope, scheduling tasks, monitoring progress, and conducting a retrospective meeting. Additionally, it promotes the use of the MindGenius tool for effective project planning and execution.Ad