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California Department of Public Health  Occupational Health Branch

Worker Fatality Alert
April 2009                                                                 Prevention Points
                                                                 Train and supervise all researchers and staff
Laboratory Research                                               on the proper procedures for using
                                                                  pyrophoric chemicals
Associate Dies of                                                Consider using other chemicals that are not
Burns From a                                                      spontaneously flammable in air
                                                              
Pyrophoric Chemical                                               Track the purchase and use of pyrophoric
                                                                  chemicals

The California Fatality Assessment and Control Evaluation (CA/FACE) program tracks and
investigates cases of fatal injuries at work, and makes prevention recommendations for employers and
employees. CA/FACE is investigating the death of a research associate who was working in a
biochemistry research laboratory at a major university. The research associate was extracting t-butyl
lithium from a reagent bottle. The chemical splashed onto her clothing and ignited, causing serious burns.
t-butyl lithium is one of a class of chemicals that are spontaneously flammable in air (pyrophoric).

                                                                         The research associate had recently
                                                                         graduated from a local college and was
                                                                         working for the year while applying to
                                                                         law school. She was working in the
                                                                         laboratory over the December holiday
                                                                         break when the incident occurred.

                                                                         The specific actions and conditions that
                                                                         led to this incident are still under
                                                                         investigation. As an immediate step to
                                                                         prevent future incidents, employers
                                                                         should ensure that safe work
                                                                         procedures are followed by all
                                                                         researchers and their staff when they
                                                                         are using pyrophoric chemicals. When
                                                                         possible, consider using chemicals that
                                                                         are not pyrophoric as this will decrease
                                                                         the risk of a serious injury if an incident
                                                                         occurs. Employers should also consider
                                                                         implementing a chemical purchasing
                                                                         and usage tracking system. This will
                                                                         help keep track of where pyrophoric
Note: Example only. Exact setup will depend on specific                  chemicals are used so that compliance
requirements. (Photo provided courtesy of John Palmer of UC San Diego)   with training and supervision can be
                                                                         ensured.

              Guidance on the safe use of pyrophoric organolithium reagents is available:
                http://membership.acs.org/c/chas/techarchive/organolithium%20paper.pdf.
(This is provided as an example only and has not been endorsed by the California Department of Public Health)


                       A complete investigation (#09CA001) of this incident is available at
                      http://www.cdph.ca.gov/programs/ohb-face/Pages/FACEReports.aspx.

                The Occupational Health Branch in the California Department of Public Health is
                 devoted to improving worker health and safety through prevention activities.
                                See http://www.cdph.ca.gov/programs/ohb

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CA/FACE Report on Pyrophoric Fatality Ucla

  • 1. California Department of Public Health Occupational Health Branch Worker Fatality Alert April 2009 Prevention Points Train and supervise all researchers and staff Laboratory Research on the proper procedures for using pyrophoric chemicals Associate Dies of Consider using other chemicals that are not Burns From a spontaneously flammable in air Pyrophoric Chemical Track the purchase and use of pyrophoric chemicals The California Fatality Assessment and Control Evaluation (CA/FACE) program tracks and investigates cases of fatal injuries at work, and makes prevention recommendations for employers and employees. CA/FACE is investigating the death of a research associate who was working in a biochemistry research laboratory at a major university. The research associate was extracting t-butyl lithium from a reagent bottle. The chemical splashed onto her clothing and ignited, causing serious burns. t-butyl lithium is one of a class of chemicals that are spontaneously flammable in air (pyrophoric). The research associate had recently graduated from a local college and was working for the year while applying to law school. She was working in the laboratory over the December holiday break when the incident occurred. The specific actions and conditions that led to this incident are still under investigation. As an immediate step to prevent future incidents, employers should ensure that safe work procedures are followed by all researchers and their staff when they are using pyrophoric chemicals. When possible, consider using chemicals that are not pyrophoric as this will decrease the risk of a serious injury if an incident occurs. Employers should also consider implementing a chemical purchasing and usage tracking system. This will help keep track of where pyrophoric Note: Example only. Exact setup will depend on specific chemicals are used so that compliance requirements. (Photo provided courtesy of John Palmer of UC San Diego) with training and supervision can be ensured. Guidance on the safe use of pyrophoric organolithium reagents is available: http://membership.acs.org/c/chas/techarchive/organolithium%20paper.pdf. (This is provided as an example only and has not been endorsed by the California Department of Public Health) A complete investigation (#09CA001) of this incident is available at http://www.cdph.ca.gov/programs/ohb-face/Pages/FACEReports.aspx. The Occupational Health Branch in the California Department of Public Health is devoted to improving worker health and safety through prevention activities. See http://www.cdph.ca.gov/programs/ohb