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The Central Dogma of
Molecular Biology
By
Engr. Ijaz-Ul-Haq
The Flow of Information
A gene is expressed in two ways
DNA is transcribed into RNA
Then RNA is translated into protein
Theme of Central Dogma
Replication
Transcription Translation
DNA RNA Protein
DNA Polymerase
Replication
DNA to DNA
RNA Polymerase
Transcription
DNA to RNA
Ribosome
Translation
RNA to Protein
DNA
RNA
Protein
Transcription Translation
DNA RNA Protein
Replication
Reverse
Transcription
Description
DNA
Stored information inside nucleus
Copied to make new cell = REPLICATION
RNA
Copied from a piece of DNA (GENE) to make a
single protein = TRANSCRIPTION
Moves information from nucleus to cytoplasm
Protein
Information from a single RNA used to make a
single protein = TRANSLATION

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Central dogma of molecular biology