1) Epidemics and pandemics typically follow 5 phases: infection peak, decline. COVID-19 has shown this pattern similarly to past viruses like H1N1 and Spanish Flu.
2) The exact causes of COVID-19 mutations and changing strains remain unknown despite research. Mathematical models of the virus's spread have often been inaccurate.
3) Potential causes of mutation include early use of antiviral drugs (inducing drug resistance), lockdowns, changing health policies and protocols, and cytokine reactions in the body.
2. *FACTS
*Any epidemic or pandemic were mostly based on 5
phases
*4th phase is the pick of the infection and 5th is the
phase of decline
*like H1N1 Every flu we observed the same phase
wise increase and decrease of the infections.
*It has high virulence factor than any other virus.
*Same scenario has been observed earlier in case of
Spanish flu.
3. *cont
*Despite of plenty of research, still we have not received
clearer picture on virus pathogenesis , cause of infection and
inclination .
*Many mathematical models or predictions has been proven
wrong around every corner of the globe at different stages.
*The actual reason behind changing of strains or mutation has
been unknown. RNA virus are often mutates but the cause of
mutation was still a big question ?
4. *Possible cause
*Use of oral antiviral drugs at early stages of
infection.
I.e. like antibiotic resistance virus may gets
resistance
*Lockdown
*shut down
*Changing guidelines, policies and medications
protocols
*Cytokine reaction