Daniel
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Furio is a contemporary Italian restaurant in Phoenix divided into three dining areas with modern decor. Dishes such as lasagna filled with crab and mushrooms and lamb with caramelized fennel showcase contemporary takes on Italian cuisine. The chocolate fondue for dessert, accompanied by berries, marshmallows and brownies, provides a decadent ending to the meal.
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- The beer selection lists various international beers like Staropramen Dark Lager, Tuborg, and Grimbergen Blonde.
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I. Nucleic Acids & Nucleotides
1. Review of the Cell
Cells are the basic structural and functional units of life. Within cells, nucleic acids (DNA and RNA) serve as essential biomolecules responsible for storing, transmitting, and expressing genetic information.
2. Structure of Nucleic Acids
Nucleic acids are long chains of nucleotides. Each nucleotide consists of three components:
A nitrogenous base (adenine, guanine, cytosine, thymine in DNA; uracil replaces thymine in RNA)
A five-carbon sugar (deoxyribose in DNA, ribose in RNA)
A phosphate group
3. Chemistry of Nucleic Acids
Nucleotides in nucleic acids are joined by phosphodiester bonds between the 3'-hydroxyl group of one sugar and the 5'-phosphate of the next, creating a sugar-phosphate backbone.
4. Nucleosides and Nucleotides
Nucleoside: Nitrogenous base + sugar
Nucleotide: Nucleoside + phosphate group Nucleotides are key components in DNA/RNA synthesis and cellular energy transfer.
5. Functions of Nucleic Acids
DNA: Stores genetic information
RNA: Involved in protein synthesis, gene regulation, and as catalytic RNA (ribozymes)
6. Biological Importance of Nucleotides
Energy carriers: e.g., ATP, GTP
Signaling molecules: e.g., cAMP
Components of coenzymes: e.g., NAD, FAD, Coenzyme A
II. Enzymology
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Enzymes act as biological catalysts, accelerating chemical reactions essential for cellular functions such as metabolism, DNA replication, and signal transduction.
2. Enzyme as Proteins
Most enzymes are globular proteins composed of specific amino acid sequences that fold into unique 3D conformations, determining the shape and specificity of the active site.
3. Properties of Enzymes
Catalytic efficiency
Specificity
Regulation
Reversibility
Sensitivity to environmental conditions (temperature, pH, etc.)
4. Enzyme Specificity
Enzymes demonstrate substrate specificity due to the geometric and chemical complementarity between the substrate and the eny denature enzymes.
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