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¡¶Á«»¨º£¡·(38) ¡¸ÎÊÓë´ð¡¹Ç£³ö¡¸Öǻۡ¹(9)-û¡¸ÃÜ×Ú¡¹µÄ¡¸×Ö¡¹£¬ÓС¸×ð¹óÃÜ¡¹µÄÒâ˼£¬´ú±íʲôÄØ£¿-Æ¡Âð¹þ×ð½ð¸ÕÉÏʦ-¶ØÖé·ðѧ»áDudjomBuddhistAssociation
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This document describes a novel protocol for the construction of 3-spiropyrrolidines and 3-spiropyrrolizidines using Baylis-Hillman adducts derived from nitroolefins via 1,3-dipolar cycloaddition reaction. Specifically, it details the successful synthesis of compound 3, a 3-spiropyrrolidine, from the Baylis-Hillman adduct 2 treated with isatin and N-methyl glycine. The compound was characterized through various analytical techniques and obtained in 62% yield. This reaction demonstrates the utility of Baylis-Hillman adducts from nitroolefins in azomethine ylide-based cycloaddition to form nitrogen-containing
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