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Evaluation of Headache in Adults

                  Bita Fakhri, MD, MPH

                  Boston Medical Center
                  Shapiro Primary Care
                   Clinic
                  2/27/2013
Evaluation of Headache in Adults

 History
 Danger signs on history
 Physical exam
 Danger signs on physical exam
 Three main classes of primary headaches
 Indications for imaging studies
History

 Age at onset
 Presence or absence of aura and prodrome
 Frequency, intensity, and duration of attack
 Number of headache days per months
 Time and mode of onset
 Quality, site and radiation of pain
 Associated symptoms and abnormalities
 Family history of migraine
 Precipitating and relieving factors
 Effect of activity on pain
History

 Relationship with food and alcohol
 Response to any previous treatment
 Any recent change in vision
 Association with recent trauma
 Any recent changes in sleep, exercise, weight, or diet
 State of general health
 Change in work or life style (disability)
 Change in method of birth control
 Possible association with environmental factors
 Effects of menstrual cycle and exogenous hormones
Danger Signs on history

 Sudden onset of headache, or severe persistent
  headache that reaches maximal intensity within a
  few seconds or minutes (? SAH)
 The absence of similar headaches in the past  the
  first or worst headache of my life (ICH, CNS
  infection)
 A worsening pattern of headache (mass
  lesion, subdural hematoma, medication overuse
  headache)
 Focal neurologic symptoms other than typical visual
  or sensory aura (mass lesion, AVM, collagen vascular
  disease)
Danger Signs on history

 Fever (infection, SAH)
 Any change in mental status, personality, or
  fluctuation in the level of consciousness
 The rapid onset of headache with strenuous exercise
  (? Carotid artery dissection or ICH)
 Head pain that spreads into the lower neck and
  between the shoulders may indicate meningeal
  irritation (infection, SAH)
 New headache in patients <5 or >50
Danger Signs on history

 New headache type in a patient with cancer suggests
  metastasis.
 New headache type in a patient with Lyme disease
  suggests meningoencephalitis.
 New headache type in a patient with HIV suggests an
  opportunistic infection or tumor.
 Headache during pregnancy or postpartum suggests
  possible cortical vein or venous sinus
  thrombosis, carotid dissection
Physical Exam

 Obtain BP and pulse
 Listen for bruits at neck, eyes, and head for clinical
    signs of AVM
   Palpate the head, neck, and shoulder regions
   Check temporal and neck arteries
   Examine the spine and neck muscles
   Functional neurologic examination
Danger Signs on Examination

 Neck stiffness and especially meningismus
  (resistance to neck flexion) suggests meningitis
 Papilledema (intracranial mass
  lesion, pseudotumorcerebri, encephalitis, or
  meningitis)
 Focal neurologic signs (intracranial
  mass, AVM, collagen vascular disease)
Characteristics of Common Headache Syndromes


   SYMPTOM          MIGRAINE             TENSION            CLUSTER
                    HEADACHE             HEADACH           HEADACHE
                                            E
   LOCATION        Unilateral in 60-       Bilateral          ALWAYS
                  70% -- bilateral or                         unilateral
                    glabal in 30%

CHARACTERISTICS     Gradual in onset,      Pressure or       Pain begins
                   crescendo pattern;    tightness that   quickly, reaches a
                  pulsating; moderate      waxes and      crescendo within
                  or severe intensity;       wanes         minutes; pain is
                     aggravated by                        deep, continuous,
                    routine physical                      excruciating, and
                         activity                            explosive in
                                                               quality
Characteristics of Common Headache Syndromes

 SYMPTOM         MIGRAINE             TENSION             CLUSTER
                 HEADACHE            HEADACHE            HEADACHE
   Patient    Patient prefers to rest Patient may       Patient remains
 appearance   in a dark, quiet room remain active or         active
                                      may need to
                                          rest
  Duration         4-72 hours           Variable          0.5-3 hours
 Associated    Nausea, vomiting,         None          Ipsilaterallacrimati
 symptoms         photophobia,                          on and redness of
               phonophobia; may                           the eye, stuffy
               have aura (usually                       nose; rhinorrhea;
                 visual, but can                        pallor; sweating;
              invlove other senses                           Horners
               or cause speech or                        syndrome; focal
                 motor deficits)                            neurologic
                                                         symptoms rare;
                                                           sensitivity to
                                                             alcohol
Treatment of Migraine Headaches

 Abortive therapy:
  ASA, tylenol, caffeine, high dose NSAIDs, triptans
 Prophylaxis:
  TCA, BB, CCB, Valproic acid, topiramate
Criteria for Transformed Migraine and Medication-Overuse Headache.




    Dodick DW. N Engl J Med 2006;354:158-165.
Preventive Medications Used in Cases of Transformed Migraine or Medication-Overuse
                                     Headache.




         Dodick DW. N Engl J Med 2006;354:158-165.
Headache
Treatment of Cluster Headaches

 Acute treatment: O2, triptans
 Chronic prophylaxis: CCB
Indications for Imaging Studies

 Recent significant change in pattern, ferequency, or
    severity of headache
   Progressive worsening of headache despite
    appropriate therapy
   Focal neurologic signs and symptoms
   Onset of headache with exertion, cough, or sexual
    activity
   Orbital bruit
   Onset of headache after age 40
CT vs. MRI

 There is no evidence that MRI > CT
 CT-brain and brainstem with and without contrast is
  sufficient in most patients.
 MRI along with MRA are indicated when posterior
  fossa or vascular lesions are suspected.
The Pain of Cluster Headache

 http://www.youtube.com/watch?v=glBmSQRxaIg

More Related Content

Headache

  • 1. Evaluation of Headache in Adults Bita Fakhri, MD, MPH Boston Medical Center Shapiro Primary Care Clinic 2/27/2013
  • 2. Evaluation of Headache in Adults History Danger signs on history Physical exam Danger signs on physical exam Three main classes of primary headaches Indications for imaging studies
  • 3. History Age at onset Presence or absence of aura and prodrome Frequency, intensity, and duration of attack Number of headache days per months Time and mode of onset Quality, site and radiation of pain Associated symptoms and abnormalities Family history of migraine Precipitating and relieving factors Effect of activity on pain
  • 4. History Relationship with food and alcohol Response to any previous treatment Any recent change in vision Association with recent trauma Any recent changes in sleep, exercise, weight, or diet State of general health Change in work or life style (disability) Change in method of birth control Possible association with environmental factors Effects of menstrual cycle and exogenous hormones
  • 5. Danger Signs on history Sudden onset of headache, or severe persistent headache that reaches maximal intensity within a few seconds or minutes (? SAH) The absence of similar headaches in the past the first or worst headache of my life (ICH, CNS infection) A worsening pattern of headache (mass lesion, subdural hematoma, medication overuse headache) Focal neurologic symptoms other than typical visual or sensory aura (mass lesion, AVM, collagen vascular disease)
  • 6. Danger Signs on history Fever (infection, SAH) Any change in mental status, personality, or fluctuation in the level of consciousness The rapid onset of headache with strenuous exercise (? Carotid artery dissection or ICH) Head pain that spreads into the lower neck and between the shoulders may indicate meningeal irritation (infection, SAH) New headache in patients <5 or >50
  • 7. Danger Signs on history New headache type in a patient with cancer suggests metastasis. New headache type in a patient with Lyme disease suggests meningoencephalitis. New headache type in a patient with HIV suggests an opportunistic infection or tumor. Headache during pregnancy or postpartum suggests possible cortical vein or venous sinus thrombosis, carotid dissection
  • 8. Physical Exam Obtain BP and pulse Listen for bruits at neck, eyes, and head for clinical signs of AVM Palpate the head, neck, and shoulder regions Check temporal and neck arteries Examine the spine and neck muscles Functional neurologic examination
  • 9. Danger Signs on Examination Neck stiffness and especially meningismus (resistance to neck flexion) suggests meningitis Papilledema (intracranial mass lesion, pseudotumorcerebri, encephalitis, or meningitis) Focal neurologic signs (intracranial mass, AVM, collagen vascular disease)
  • 10. Characteristics of Common Headache Syndromes SYMPTOM MIGRAINE TENSION CLUSTER HEADACHE HEADACH HEADACHE E LOCATION Unilateral in 60- Bilateral ALWAYS 70% -- bilateral or unilateral glabal in 30% CHARACTERISTICS Gradual in onset, Pressure or Pain begins crescendo pattern; tightness that quickly, reaches a pulsating; moderate waxes and crescendo within or severe intensity; wanes minutes; pain is aggravated by deep, continuous, routine physical excruciating, and activity explosive in quality
  • 11. Characteristics of Common Headache Syndromes SYMPTOM MIGRAINE TENSION CLUSTER HEADACHE HEADACHE HEADACHE Patient Patient prefers to rest Patient may Patient remains appearance in a dark, quiet room remain active or active may need to rest Duration 4-72 hours Variable 0.5-3 hours Associated Nausea, vomiting, None Ipsilaterallacrimati symptoms photophobia, on and redness of phonophobia; may the eye, stuffy have aura (usually nose; rhinorrhea; visual, but can pallor; sweating; invlove other senses Horners or cause speech or syndrome; focal motor deficits) neurologic symptoms rare; sensitivity to alcohol
  • 12. Treatment of Migraine Headaches Abortive therapy: ASA, tylenol, caffeine, high dose NSAIDs, triptans Prophylaxis: TCA, BB, CCB, Valproic acid, topiramate
  • 13. Criteria for Transformed Migraine and Medication-Overuse Headache. Dodick DW. N Engl J Med 2006;354:158-165.
  • 14. Preventive Medications Used in Cases of Transformed Migraine or Medication-Overuse Headache. Dodick DW. N Engl J Med 2006;354:158-165.
  • 16. Treatment of Cluster Headaches Acute treatment: O2, triptans Chronic prophylaxis: CCB
  • 17. Indications for Imaging Studies Recent significant change in pattern, ferequency, or severity of headache Progressive worsening of headache despite appropriate therapy Focal neurologic signs and symptoms Onset of headache with exertion, cough, or sexual activity Orbital bruit Onset of headache after age 40
  • 18. CT vs. MRI There is no evidence that MRI > CT CT-brain and brainstem with and without contrast is sufficient in most patients. MRI along with MRA are indicated when posterior fossa or vascular lesions are suspected.
  • 19. The Pain of Cluster Headache http://www.youtube.com/watch?v=glBmSQRxaIg