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Homeostasis
Biology 2: Form and Function
MOHD ASIF KANTH
M.SC ZOOLOGY ,B.ED
9070262786
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Overview
 Homeostasis = maintenance of
constant internal environment
 Physiological controls
 Negative feedback loops
 Positive feedback loops
 Behavioral controls
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Osmoregulation
 Water is vital to the chemistry of life
 Therefore, must attain a water balance
within the body
 Water balance systems are based on three
processes:
 Diffusion
 Osmosis
 Active transport
 Osmoregulation processes often tied to
excretion aasifibrahim786@gmail.com/asifkant
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 Diffusion
 The spread of molecules along a
concentration gradient by brownian motion,
towards a state of entropy
 Osmosis (the diffusion of water)
 Water moves from a low solute
concentration (hypotonic) to a high solute
concentration (hypertonic)
 Active transport
 The movement of molecules across a
membrane, usually against a gradient,
involving the expenditure of energy
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Osmoregulation in invertebrates
 Since most invertebrate phyla evolved
in water, no shortage
 However, differences in concentration
between the cell and the solution
surrounding it may cause problems
 e.g., Amoeba in freshwater: hypertonic cell
in hypotonic solution
 Result: movement of water into cell
 Defense: Contractile vacuole pumps out
water aasifibrahim786@gmail.com/asifkant
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 Multicellular organisms use transport
epithelia to control water loss and excretion
 Platyhelminthes
 Protonephridia (flame cells) collect excess water in
addition to nitrogenous wastes, empty into
nephridiopore, excretes NH3
 Annelida
 Metanephridia organized on a per segment basis
collect waste from coelom via the nephrostome,
counters water uptake by epidermis, excretes NH3
 Insecta
 Malpigian tubules collect nitrogenous wastes from
haemocoel, excretes Uric Acidaasifibrahim786@gmail.com/asifkant
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Osmoregulation in fish
 Depends on environment
 Freshwater
 Cells are hypertonic to environment, must
defend against water uptake
 Excretion of dilute urine
 Mucous covering of epidermis
 Marine
 Cells are hypotonic to environment, must
defend against water loss
 Water gain through food uptake and drinking
 Concentration of urine
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Filtration
 Occurs in Bowmans capule
 Afferent arteriole from renal artery enters
glomerulus, exits via efferent arteriole
 Blood filtered by capsule: all non-cellular
products pushed into nephron (proximal
tubule)
 Filtrate includes products that must be
retained: blood sugars, salts and vitamins
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Secretion
 Occurs in proximal and distal tubule
 Secretion is initially active, although
certain molecular transport occurs
passively as a result
 e.g., NaCl actively pumped out, H2O
follows
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Reabsorption
 Materials that must be retained are
brought back by active transport or
passive diffusion
 Result of absorption/secretion in Loop
of Henle is highly concentrated urine
 Nephron tubule is lined by transport
epithelia
 Amount of water retained is controlled
by hormones that control activity of
transport epitheliaaasifibrahim786@gmail.com/asifkant
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The Loop of Henle
 Descending limb is permeable to water but
not NaCl
 H2O moves by osmosis to high salt
concentration in interstitial fluid
 Thin segment of ascending limb is
permeable to NaCl which moves passively
by diffusion to equalize gradient
 Thick segment of ascending limb actively
transports NaClaasifibrahim786@gmail.com/asifkant
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