The document discusses size reduction, which is the process of reducing the size of solid materials through mechanisms like impact, attrition, compression, and cutting. Size reduction is important to increase surface area for applications like reactions. Common size reduction equipment includes crushers, grinders, and cutting machines. Crushers are used for coarse size reduction through impacts. Grinders provide intermediate and fine size reduction through impacts or abrasion. Factors that influence equipment choice include the feed and desired product sizes, material properties, and capacity needs. The efficiency of size reduction depends on factors like the energy required to generate new surface area.
This document discusses size reduction, which is the process of decreasing the size of particles through mechanical means. It defines size reduction and describes various factors that affect the process, such as hardness, moisture content, and material structure. Several common size reduction methods are also outlined, including hammer mills, ball mills, roller mills, and colloidal mills. The key theories relating to energy input and particle size are explained as well. Overall, the document provides an overview of size reduction techniques and considerations.
The document discusses size reduction which involves reducing the size of solid particles through various techniques. It describes the objectives of size reduction such as obtaining specific particle sizes and surface areas. It then covers different types of size reduction equipment used for coarse, intermediate and fine size reduction such as jaw crushers, cone crushers and ball mills. It also discusses factors that influence size reduction like material properties, moisture content and reduction ratio. Laws governing energy requirements during size reduction like Kick's law, Rittinger's law and Bond's law are also summarized.
This document discusses size reduction in food processing. It covers the principles of size reduction using forces like compression, impact, shear and cutting. It describes various size reduction equipment like crushers, hammer mills, attrition mills, ball mills and cutting machines. It also discusses size reduction in liquid foods through emulsification and homogenization using high shear mixers, pressure homogenizers, colloid mills and ultrasonic homogenizers.
This document discusses size reduction and comminution. It outlines the objectives of size reduction such as improving flow properties and increasing surface area. It examines how material properties like brittleness, toughness, and hardness influence size reduction. Different size reduction methods are described, including cutting, compression, impact, attrition, and combined impact/attrition. Specific equipment like ball mills, hammer mills, and fluidized mills are discussed in terms of how they achieve size reduction through impacts and attrition. Factors that influence particle size distribution changes during milling are also covered.
This document discusses size reduction in pharmaceutical engineering. It begins with an introduction that defines size reduction as reducing large solid masses into smaller particles through mechanical means like grinding and cutting. It then covers the main size reduction mechanisms of compression, impact, attrition and cutting. Several laws governing size reduction are presented, including Kick's law, Rittinger's law, and Bond's law. The key factors affecting size reduction are listed as material hardness, toughness, stickiness, and moisture content. Common size reduction equipment like hammer mills, ball mills and fluid energy mills are also described. The objectives and advantages of size reduction in pharmaceutical applications are stated.
Size reduction is a process of reducing large solid unit masses into small unit masses, coarse particles or fine particles.
Size reduction process is also termed as
Comminution/Diminution/Pulverizations.
Solid pieces of food is reduced by the
application of grinding, compression
or impact forces.
In many food processes it is frequently
necessary to reduce the size of solid
materials for different purposes.
Size reduction is a process of reducing large solid unit masses into small unit masses, coarse particles or fine particles.
Size reduction process is also termed as
Comminution/Diminution/Pulverizations.
Solid pieces of food is reduced by the
application of grinding, compression
or impact forces.
In many food processes it is frequently
necessary to reduce the size of solid
materials for different purposes
This will provide indetail information about Size reduction such as in brief about size reduction, major principles governing to size reduction, Laws for size reduction and Major Size reduction equipment using in food industries,
The document discusses size reduction techniques. It defines size reduction as reducing substances to smaller particles through mechanical means like milling. The objectives of size reduction include improving drug dissolution and absorption. Size reduction is achieved through mechanisms like cutting, compression, impact and attrition. Factors that affect size reduction include the material properties, product requirements, and safety and economic considerations. Common equipment for size reduction discussed are hammer mills, ball mills, fluid energy mills, edge runner mills, and end runner mills.
size reduction,laws involved in size reduction ,application & millsM Swetha
油
size reduction basic principles,laws&machanism of size reduction with all mills .I gave a note on size separation .it is very useful for the teaching staff &students of B.pharmacy
The document presents information on size reduction in food processing. It discusses the principles and mechanisms of size reduction using forces like compression, impact, attrition and shear. It covers the energy requirements and classification of size reduction processes. Various size reduction equipment are described, including crushers, grinders, cutting machines and fine grinders. Crushers like roll crushers are used to break large pieces into small lumps. Grinders like attrition mills, hammer mills and ball mills reduce materials to powders using forces like impact and shear. Cutting machines slice, dice, shred and pulp foods.
Size reduction is the process of decreasing the physical dimensions of objects or materials by breaking them into smaller pieces. It is done by applying external forces to break larger particles into smaller ones. The main objectives of size reduction are to increase surface area for reactions, separate materials, improve handling and mixing. Some common size reduction methods are impact, compression, shear and attrition. Key factors that affect size reduction are the material's hardness, structure, abrasiveness, softening temperature and moisture content. Several theories describe the energy required for size reduction, including Rittinger's, Bond's and Kick's theories. Only about 10% of the total energy input is actually used to reduce particle size.
The document discusses various methods of size reduction used in pharmaceutical processing. It describes common size reduction equipment like ball mills, fluid energy mills, colloidal mills, and hammer mills. For each method and equipment, it provides details on working principles, advantages, disadvantages, and applications. It also discusses theories of size reduction proposed by Rittinger, Bond, and Kick which relate energy requirements to changes in particle size and surface area.
The document discusses various theories of size reduction and milling equipment used in size reduction processes. It describes Rittinger's, Bond's, Kick's, and Walker's theories of size reduction, which propose relationships between energy input and particle size reduction. It also outlines advantages and disadvantages of common size reduction equipment like hammer mills, ball mills, and roller mills. Roller mills can be used to grind hard, non-fibrous materials into a narrow particle size range.
SIZE REDUCTION AND FACTORS AFFECTING SIZE REDUCTION IN PHARMACEUTICAL INDUSTRYAkankshaPatel55
油
In the realm of pharmacy, size truly matters! Particle size reduction, often referred to as comminution, plays a crucial role in transforming raw materials into effective and readily absorbable medications. It's like shrinking giants - turning bulky substances into microscopic warriors ready to combat ailments.
Why is size reduction so important? Imagine trying to swallow a whole apple compared to taking a bite. The smaller the pieces, the greater the surface area exposed, and the faster and more efficiently something dissolves or reacts. In the world of medicine, this translates to:
Enhanced drug bioavailability: Smaller particles dissolve quicker and more readily in the digestive system, leading to faster absorption and action of the medication. Think of it as opening wider doors for the drug to enter the bloodstream and reach its target.
Improved drug stability: Smaller particles tend to be more stable and less prone to degradation, ensuring the medication's potency and effectiveness over time.
Uniformity and mixing: Precise size control allows for consistent drug distribution within a dosage form, guaranteeing accurate and reliable dosing.
Tailored drug delivery: Size reduction facilitates the development of specialized drug delivery systems, like inhalers or sublingual tablets, where minute particles are crucial for targeted action.
How is size reduction achieved? A variety of techniques are employed, each with its own advantages and best suited for specific materials:
Milling: Mechanical grinding using ball mills, hammer mills, or jet mills physically breaks down larger particles into smaller ones.
Micronization: Specialized techniques like air jet milling or fluidized bed milling achieve ultra-fine particle sizes in the micron range (1-10 micrometers).
Cryo-milling: Grinding at cryogenic temperatures minimizes heat generation, preserving sensitive drug compounds.
Size reduction isn't just about brute force. Choosing the right technique and particle size depends on various factors, including the drug's physical and chemical properties, desired release profile, and dosage form. It's a delicate dance between effectiveness, stability, and manufacturability.
The impact of size reduction extends far beyond individual medications. It enables the development of innovative drug delivery systems, like controlled-release tablets or transdermal patches, that improve patient compliance and treatment outcomes. It also plays a vital role in research and development, allowing scientists to study drug interactions and optimize formulations at the microscopic level.
So, the next time you pop a pill, remember the invisible giants behind it - the power of size reduction silently working its magic to deliver healing and hope.
The document discusses various theories of size reduction, including Rittinger's, Bond's, Kick's, and Walker's theories. It also covers different types of equipment used for size reduction, including hammer mills, ball mills, and roller mills. Rittinger's theory suggests energy required is proportional to new surface area created. Bond's theory states energy used for crack propagation is proportional to new crack length. Kick's theory relates energy to ratio of size change, and Walker's theory generalized the energy-size relationship. Advantages and disadvantages of hammer mills, ball mills, and roller mills are provided.
This document discusses size reduction, which is the process of reducing large solid masses into smaller particles or powder. It can be achieved through mechanical or chemical methods. The key factors that affect size reduction are the hardness, toughness, abrasiveness, stickiness, and moisture content of the material. Larger surface area and smaller particle size can increase properties like solubility, adsorption, and absorption. Common size reduction methods include cutting, compression, impact, and attrition. Ball mills and fluid energy mills are described as examples. Energy requirements depend on theories like Rittinger's, Bond's, and Kick's, relating to the work required based on new surface area, particle size, and material properties.
Size reduction is the process of reducing larger particles into smaller particles using external forces. The key mechanisms of size reduction are cutting, compression, impact, attrition, and a combination of impact and attrition. Different types of mills use these mechanisms, including hammer mills, ball mills, fluid energy mills, edge runner mills, and end runner mills. The energy required for size reduction depends on factors like the material hardness, toughness, stickiness, and moisture content. Proper mill selection and operation are necessary to efficiently reduce particle sizes.
Size reduction is the process of reducing larger particles into smaller particles using external forces. The key mechanisms of size reduction are cutting, compression, impact, attrition, and a combination of impact and attrition. Different types of mills use these mechanisms, including hammer mills, ball mills, fluid energy mills, edge runner mills, and end runner mills. Factors like hardness, toughness, stickiness, softening temperature, and moisture content affect how easily a material can undergo size reduction. Laws of Rittinger, Kick, and Bond govern the energy requirements for size reduction.
This document discusses size reduction and comminution. It outlines the objectives of size reduction such as improving flow properties and increasing surface area. It examines how material properties like brittleness, toughness, and hardness influence size reduction. Different size reduction methods are described, including cutting, compression, impact, attrition, and combined impact/attrition. Specific equipment like ball mills, hammer mills, and fluidized mills are discussed in terms of how they achieve size reduction through impacts and attrition. Factors that influence particle size distribution changes during milling are also covered.
This document discusses size reduction in pharmaceutical engineering. It begins with an introduction that defines size reduction as reducing large solid masses into smaller particles through mechanical means like grinding and cutting. It then covers the main size reduction mechanisms of compression, impact, attrition and cutting. Several laws governing size reduction are presented, including Kick's law, Rittinger's law, and Bond's law. The key factors affecting size reduction are listed as material hardness, toughness, stickiness, and moisture content. Common size reduction equipment like hammer mills, ball mills and fluid energy mills are also described. The objectives and advantages of size reduction in pharmaceutical applications are stated.
Size reduction is a process of reducing large solid unit masses into small unit masses, coarse particles or fine particles.
Size reduction process is also termed as
Comminution/Diminution/Pulverizations.
Solid pieces of food is reduced by the
application of grinding, compression
or impact forces.
In many food processes it is frequently
necessary to reduce the size of solid
materials for different purposes.
Size reduction is a process of reducing large solid unit masses into small unit masses, coarse particles or fine particles.
Size reduction process is also termed as
Comminution/Diminution/Pulverizations.
Solid pieces of food is reduced by the
application of grinding, compression
or impact forces.
In many food processes it is frequently
necessary to reduce the size of solid
materials for different purposes
This will provide indetail information about Size reduction such as in brief about size reduction, major principles governing to size reduction, Laws for size reduction and Major Size reduction equipment using in food industries,
The document discusses size reduction techniques. It defines size reduction as reducing substances to smaller particles through mechanical means like milling. The objectives of size reduction include improving drug dissolution and absorption. Size reduction is achieved through mechanisms like cutting, compression, impact and attrition. Factors that affect size reduction include the material properties, product requirements, and safety and economic considerations. Common equipment for size reduction discussed are hammer mills, ball mills, fluid energy mills, edge runner mills, and end runner mills.
size reduction,laws involved in size reduction ,application & millsM Swetha
油
size reduction basic principles,laws&machanism of size reduction with all mills .I gave a note on size separation .it is very useful for the teaching staff &students of B.pharmacy
The document presents information on size reduction in food processing. It discusses the principles and mechanisms of size reduction using forces like compression, impact, attrition and shear. It covers the energy requirements and classification of size reduction processes. Various size reduction equipment are described, including crushers, grinders, cutting machines and fine grinders. Crushers like roll crushers are used to break large pieces into small lumps. Grinders like attrition mills, hammer mills and ball mills reduce materials to powders using forces like impact and shear. Cutting machines slice, dice, shred and pulp foods.
Size reduction is the process of decreasing the physical dimensions of objects or materials by breaking them into smaller pieces. It is done by applying external forces to break larger particles into smaller ones. The main objectives of size reduction are to increase surface area for reactions, separate materials, improve handling and mixing. Some common size reduction methods are impact, compression, shear and attrition. Key factors that affect size reduction are the material's hardness, structure, abrasiveness, softening temperature and moisture content. Several theories describe the energy required for size reduction, including Rittinger's, Bond's and Kick's theories. Only about 10% of the total energy input is actually used to reduce particle size.
The document discusses various methods of size reduction used in pharmaceutical processing. It describes common size reduction equipment like ball mills, fluid energy mills, colloidal mills, and hammer mills. For each method and equipment, it provides details on working principles, advantages, disadvantages, and applications. It also discusses theories of size reduction proposed by Rittinger, Bond, and Kick which relate energy requirements to changes in particle size and surface area.
The document discusses various theories of size reduction and milling equipment used in size reduction processes. It describes Rittinger's, Bond's, Kick's, and Walker's theories of size reduction, which propose relationships between energy input and particle size reduction. It also outlines advantages and disadvantages of common size reduction equipment like hammer mills, ball mills, and roller mills. Roller mills can be used to grind hard, non-fibrous materials into a narrow particle size range.
SIZE REDUCTION AND FACTORS AFFECTING SIZE REDUCTION IN PHARMACEUTICAL INDUSTRYAkankshaPatel55
油
In the realm of pharmacy, size truly matters! Particle size reduction, often referred to as comminution, plays a crucial role in transforming raw materials into effective and readily absorbable medications. It's like shrinking giants - turning bulky substances into microscopic warriors ready to combat ailments.
Why is size reduction so important? Imagine trying to swallow a whole apple compared to taking a bite. The smaller the pieces, the greater the surface area exposed, and the faster and more efficiently something dissolves or reacts. In the world of medicine, this translates to:
Enhanced drug bioavailability: Smaller particles dissolve quicker and more readily in the digestive system, leading to faster absorption and action of the medication. Think of it as opening wider doors for the drug to enter the bloodstream and reach its target.
Improved drug stability: Smaller particles tend to be more stable and less prone to degradation, ensuring the medication's potency and effectiveness over time.
Uniformity and mixing: Precise size control allows for consistent drug distribution within a dosage form, guaranteeing accurate and reliable dosing.
Tailored drug delivery: Size reduction facilitates the development of specialized drug delivery systems, like inhalers or sublingual tablets, where minute particles are crucial for targeted action.
How is size reduction achieved? A variety of techniques are employed, each with its own advantages and best suited for specific materials:
Milling: Mechanical grinding using ball mills, hammer mills, or jet mills physically breaks down larger particles into smaller ones.
Micronization: Specialized techniques like air jet milling or fluidized bed milling achieve ultra-fine particle sizes in the micron range (1-10 micrometers).
Cryo-milling: Grinding at cryogenic temperatures minimizes heat generation, preserving sensitive drug compounds.
Size reduction isn't just about brute force. Choosing the right technique and particle size depends on various factors, including the drug's physical and chemical properties, desired release profile, and dosage form. It's a delicate dance between effectiveness, stability, and manufacturability.
The impact of size reduction extends far beyond individual medications. It enables the development of innovative drug delivery systems, like controlled-release tablets or transdermal patches, that improve patient compliance and treatment outcomes. It also plays a vital role in research and development, allowing scientists to study drug interactions and optimize formulations at the microscopic level.
So, the next time you pop a pill, remember the invisible giants behind it - the power of size reduction silently working its magic to deliver healing and hope.
The document discusses various theories of size reduction, including Rittinger's, Bond's, Kick's, and Walker's theories. It also covers different types of equipment used for size reduction, including hammer mills, ball mills, and roller mills. Rittinger's theory suggests energy required is proportional to new surface area created. Bond's theory states energy used for crack propagation is proportional to new crack length. Kick's theory relates energy to ratio of size change, and Walker's theory generalized the energy-size relationship. Advantages and disadvantages of hammer mills, ball mills, and roller mills are provided.
This document discusses size reduction, which is the process of reducing large solid masses into smaller particles or powder. It can be achieved through mechanical or chemical methods. The key factors that affect size reduction are the hardness, toughness, abrasiveness, stickiness, and moisture content of the material. Larger surface area and smaller particle size can increase properties like solubility, adsorption, and absorption. Common size reduction methods include cutting, compression, impact, and attrition. Ball mills and fluid energy mills are described as examples. Energy requirements depend on theories like Rittinger's, Bond's, and Kick's, relating to the work required based on new surface area, particle size, and material properties.
Size reduction is the process of reducing larger particles into smaller particles using external forces. The key mechanisms of size reduction are cutting, compression, impact, attrition, and a combination of impact and attrition. Different types of mills use these mechanisms, including hammer mills, ball mills, fluid energy mills, edge runner mills, and end runner mills. The energy required for size reduction depends on factors like the material hardness, toughness, stickiness, and moisture content. Proper mill selection and operation are necessary to efficiently reduce particle sizes.
Size reduction is the process of reducing larger particles into smaller particles using external forces. The key mechanisms of size reduction are cutting, compression, impact, attrition, and a combination of impact and attrition. Different types of mills use these mechanisms, including hammer mills, ball mills, fluid energy mills, edge runner mills, and end runner mills. Factors like hardness, toughness, stickiness, softening temperature, and moisture content affect how easily a material can undergo size reduction. Laws of Rittinger, Kick, and Bond govern the energy requirements for size reduction.
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Lect 8-Seperation Process 1 Dr. ALI AL-SHATRI .pdf
1. Mixing equipment
The efficiency and homogeneity of the mixing process significantly impact
the quality of the final product. Several types of equipment are employed
in industrial to achieve optimal mixing of solid particles. Here's an
overview of some commonly used industrial solid particles mixing
equipment:
For paste and heavy material
Pony mixer
Beater mixer
Kneader mixer
For granular solids
Tumbling mixer
Ribbon mixer
Vertical screw mixer
Paddle mixer
2. Mixers for paste and heavy material
Change can mixers:
Theses devices blend viscous liquids
or light pastes, as in food processing
or paint manufactures. A small
removable can 5-100 gal size holds
the material to be mixed.
3. Mixers for free-flowing solids (granular solids)
(a) (b)
Ribbon mixer: it has its unique twisted blades shaped like the inner
blade bar, are set up within static shell by rotating blades.
- Main mechanism is convective mixing
- Accompanied with diffuse and shear mixing
Tumbling mixer: Closed vessel rotating about its axis (cube, cone, or V shape).
- Main mechanism is diffuse mixing
- Problem segregation in free-flowing powders (to minimize use baffles)
4. Mixers for free-flowing solids (granular solids)
Vertical screw mixer
Paddle mixer
Paddle mixer: it I known as paddle blender, it has efficient and gentle
mixing action making it suitable for fragile or heat-sensitive material..
- Main mechanism is convective mixing with rotational motion.
Vertical screw mixer: it has its uniform mixing of materials through the
rotation and pushing screw. It has difficulty in handling sticky or
cohesive materials.
- Main mechanism is convective mixing
- Accompanied with diffuse and shear mixing
5. SIZE REDUCTION
What is the meaning of size reduction?
Size refers to physical dimension of an object.
Reduction refers to decrement or the process of
decreasing the size.
10. Type of IMPACT
Gravity impact
In gravity impact ,the free falling material is momentarily stopped by
the stationary object.
Example coal dropped onto a hard steel surface.
Dynamic impact
Most often used when it is necessary to separate two materials which
have relatively different friability.
Example material dropping in front of a moving hammer.
13. Energy for size reduction
It was shown that the energy (dE) required to effect a small change in
the size of unit mass of material (dL) is a simple power function of
size.
Where; P is a constant
C is a coefficient
Three empirical laws have been proposed to solve the above
14. Energy for size reduction
1. Rittingers law (1867): In this law, P is put equal to (-2) Energy for size reduction
Put
Where is Rittingers constant ( )
is the crushing strength of the material ( )
The interpretation of this law is that the energy required for size reduction is
directly proportional to the increase in surface.
/
/
= 告
15. Energy for size reduction
2. Kicks law (1885): In this law, P is put equal to (-1)
Put
Where is Kicks constant ( )
is the crushing strength of the material ( )
The energy required to crush a given amount is directly related to the reduction
ratio
叶
叶
.
/
/
= 告
= 告
叶
叶
C
16. Energy for size reduction
Neither of these two laws give an accurate calculation of the energy
requirements.
Rittingers law is applicable mainly to that part of the process where
the increase in surface per unit mass of material is large, i.e. used for
fine grinding.
Kicks law, however, is more accurate than Rittingers law for coarse
crushing where the amount of surface produced is considerably less.
17. Energy for size reduction
3. Bonds law (1952): Bond has suggested a law intermediate between Rittingers and
Kicks laws, by putting P = 3/2. After integration we get:
Where : the work index which represents the amount of energy required to reduce unit mass
of material from an particle size 叶 to a size 叶 of 100 亮m.
The size of material is taken as the size of the square hole through which 80 % of the
material will pass.
20. What is the power required to crush 100 ton/h of limestone if 80 percent of the feed
passes a 2-in screen and 80 percent of the product a 1/8-in screen?
Solution:
Form pervious Table, the work index for limestone is 12.74 (KW.h/ton)
The power required to crush is
Example:
= 艶.
. 艶
= 169.57 KW
叶 = . = . 叶 = . . = .
動
= /
=
叶
叶
=