The document provides tips for making the best use of one's time. It recommends prioritizing tasks using a priority matrix and to-do list, developing a bias for action while minimizing distractions and avoiding multitasking. It also suggests thinking strategically by learning how to think, sharpening skills, developing oneself, learning skills that require no talent, being conscious of intentions, and dedicating time to reading everyday. The overall guidance is to manage one's self effectively through prioritizing and strategic thinking to make the most of time.