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Prepared by:
Shorouq Alhoutary
Physiology of thirst
Physiology of thirst
Physiology of thirst
Physiology of thirst
Physiology of thirst
Physiology of thirst
Physiology of thirst
Physiology of thirst
Physiology of thirst
Physiology of thirst
Physiology of thirst
Physiology of thirst
 Under normal conditions, most
water intake is due NOT to thirst but
to
 social factors
 cultural factors
 (e.g. drinking with meals or at
work breaks, water in food)
Fluid Physiology
Thirst
Thirst
How do we feel
thirsty?
There are 4
stimuli for thirst
Hypertonicity
Hypertonicity
Hypovolaemia
Hypertonicity
Hypovolaemia
Hypotension
Hypertonicity
Hypovolaemia
Hypotension
Angiotensin II
I. Hypertonicity
 Higher concentration of
solutes outside the cell
than inside the cell >
cellular dehydration
 Causes:
 High sodium diet
II. Hypovolaemia
 Decreased blood volume;
more specifically, decrease
in volume of blood plasma
(ICF volume is decreased)
 Causes:
 Haemorrhage
III. Hypotension
 = low blood pressure
 Causes:
 Pregnancy
 Heart problems
 Endocrine problems
 Haemorrhage
 Dehydration .. etc
VI. Angiotensin II
Hypertonicity
Osmorec
eptors
in the
hypothala
mus
Hypertonicity
Hypovolaemia
Osmorec
eptors
in the
hypothala
mus
Low
pressure
baroreceptor
s in the great
veins and
right atrium
Hypertonicity
Hypovolaemia
Hypotension
Osmorec
eptors
in the
hypothala
mus
Low
pressure
baroreceptor
s in the great
veins and
right atrium
High
pressure
baroreceptor
s in carotid
sinus & aorta
Hypertonicity
Hypovolaemia
Hypotension
Angiotensin II
Osmorec
eptors
in the
hypothala
mus
Low
pressure
baroreceptor
s in the great
veins and
right atrium
High
pressure
baroreceptor
s in carotid
sinus & aorta
consequent to
the release of
renin by the
kidney (in
response to
renal
hypotension)
In
Summary ..
Physiology of thirst
Physiology of thirst
Thank You
Any Question?
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Physiology of thirst