2. Broad objective
By the end of this presentation the participants should be able to
acquire knowledge , attitude and skill toward pneumocystic
jirovecii pneumonia
3. Specific objective
By the end of this presentation participants should be able to :
Explain the aetiology of pneumocystic jirovecci pneumonia
Describe the causative organisms of pneumocystic jirovecci
pneumonia
Explain the clinical manifestation of of pneumocystic jirovecci
pneumonia
Explain the medical management of this condition
Explain the nursing management of pneumocystic jirovecci
pneumonia
4. Description
It is a rare, serious lung infection that causes inflammation and
fluid build up.
It is caused by a fungi known as pneumocystis jirovecii. This fungi
spreads by air.
This infection is very common in people who have a weaken
immunity which includes those people living with HIV and AIDS.
In very rare cases, the infection can infect other parts of the body
such as the liver, lymph nodes and the bone marrow.
5. Epidimiology
before the widespread use of prophylaxis for pjp the
frequency of the disease was high
pjp occured in 70-80% of patients with HIV infections
in developing countries pjp was thought to be lower but
atudies showed that this was a failure to diagnose pjp
accurately
in 2005 pnuemocystis infection increased in africa 80%
of infants with pnuemonia who had HIV infection
6. Risk factors
Patients with HIV and immunocompromised patients
Age less than 1yr
People whove had organ transplants
People who take drugs for autoimmune diseases
People with blood cancers
7. Pathophysiology
The pneumonia attaches to the alveolar epithelium where it
transforms from its smallest trophic form to larger cystic form.
This attachment causes the body to react causing injury and
impaired gas exchange which can later result in respiratory
failure.
10. Clinical signs
Patients present with the following:
Extreme shortness of breath
Dry cough
Fever may or may not be present
(Tachypnoea, dyspnoea and hypoxia)
In infants less than 2 months, signs of severe pneumonia will be
seen(Tachypnoea, dyspnoea and hypoxia)
12. Medical management
Give cotrimoxazole 120mg/kg/day in three divided doses. Give IV
or through an NGT if patient is unable to swallow.
If hypoxic or in respiratory distress, give prednisolone 2mg/kg in
24hrs for 7 days then 1mg/kg in 24hrs for 7 days then 0.5mg/kg in
24hrs for 7 days.
Start ARVs if AIDS is causing the condition.
administer benzyl penicillin 50000 units/kg/dose 12hrly,
thereafter 6hrly for children in their first week of life.
13. NURSING DIAGNOSIS
Ineffective airway clearance related to increased production of
secretions as evidenced by presence of crackles.
Impaired gas exchange related to inflammation and presence of
fluid and mucus in the lungs as evidenced by dyspnoea
Ineffective coping mechanism(anxiety) related to disease
prognosis as evidenced guardians asking too many questions.
14. Nursing management goal
Patient should maintain clear, patent airway
Patient manifests absence of signs and symptoms of respiratory
distress
Guardians verbalise concerns about the health status of the child.
15. NURSING MANAGEMENT
Ensure adequate hydration assist in thing secretions
Allow and encourage the child to assume position of choice
Administer analgesics if there is pain due to coughing as
prescribed
Provide supplemental oxygen
Provide education to parents and guardians
administer prescribed drugs
16. complications
Lymphadenopathy
Bone marrow involvement
Involvement of the GIT and thyroid
Acute respiratory distress syndrome
Respiratory failure
17. Prevention
Lifelong maintenance of cotrimoxazole
Keep up with ART
children born to mothers with HIV infection ahould recieve
prophylaxis