This patient has a rare blood disorder called TTP and is at high risk of infection due to immunosuppressant treatments. While starting a new treatment, the medical team will closely monitor for infection given other health issues. A tracheostomy may be needed to help breathing but will only be considered carefully over the next week based on the patient's condition and risks versus benefits. The team is very concerned about the patient's frailty and limited chances of survival due to the disease and prior health.
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28. This frail patient has recurrent, resistant TTP with cerebral
involvement. He is due to start rituximab after having high dose
steroids, immunosuppressants, PLEX and TTP. He has a high urea which
is a concern given his steroid use and the possibility of GI bleeding. He
is clearly at high risk of infection and we will actively monitor for this.
Given his challenges and no evidence of seizures on an EEG, a
tracheostomy may be needed but will need to be carefully timed.
Given the benefits and burdens of this in the context of his illness and
treatments, and that he is now starting to follow some commands, we
will consider this carefully over the coming week.