3. Thread 1:
You cant begin to understand things like
aggression, competition, cooperation, and
empathy without biology. But youre
just as
much up
the creek
if you only
rely on
biology
(pg. 4)
4. Thread 2:
Hot-blooded badness and warm-hearted
goodness raise a key point, encapsulated in
a quote from Elie Wiesel: The opposite of
love is not hate
its indifference.
The biologies of
strong love and
strong hate are
similar in
many ways.
(pg. 19)
5. Thread 3:
There really arent centers in the brain for
particular behaviors. There arent centers for
feeling pissy or horny, for feeling bittersweet
nostalgia, or warm
protectiveness tinged
with contempt. No
surprise then that
circuitry connecting
various limbic struc-
tures is immensely
complex.
(pg. 25)
6. Thread 4:
Depression is fundamentally a patho-
logical sense of loss of control (learned
helplessness)
When childhood
traumas produce
depression, there
is overgeneral-
ization:Life will
always be uncon-
trollably awful.
(pg. 197)
7. Thread 5:
Nearly every facet of
the nuts and bolts of
neurotransmitterology
can be changed by
experience.
(pg. 694)
9. Thread 7:
People (who feel anothers pain most
strongly), with the most pronounced
arousal and
anxiety, are
actually less
likely to act
prosocially.
(pg. 169)
10. Thread 8:
Because it is the last (area of the brain)
to mature, by definition the frontal cortex
is the brain
region least
constrained
by genes
and most
sculpted by
experience.
(pg. 173)
12. Thread 10:
Some things that can influence grit:
prenatal environment
birth family socioeconomics
blood glucose levels
sleep quality & quantity
childhood abuse
dopamine D4 receptors
parasite infection
lead levels in tapwater
glucocorticoid levels
(pg. 597)
13. Thread 11:
Some facts: the amygdala activates when
seeing the face of another race; oxytocin
makes us crappy to strangers; gene variants
can make us antisocial; if youre poor,
frontal development lags behind average;
there are
grounds for
optimism !
(pg. 614)