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 What is Vitamin
?
INTRODUCTION
Vitamins (English: vital amine, vitamins) are a
group of small-molecular-weight organic
compound which has a vital function in the
metabolism of every organism, which can not
be produced by the body. The name is derived
from the combination of the Latin word vita
which means "life" and amine(amine) that
refers to an organic group that has a nitrogen
atom (N)
Vitamins have a specific role
in the body and can also
provide health benefits. If
levels of these compounds is
insufficient, the body can
suffer a disease.
There are 13 types
of vitamins needed by the
body to be able to grow and
develop properly.
VITAMIN E
Scientific name of vitamin E is
Tocopherol.
Vitamin E plays a role in maintaining the
health of various tissues in the body,
ranging from skin tissue, eyes, red blood
cells to the liver. In addition,
this vitamin can also protect human lungs
from air pollution. Vitamin E is found in
fish, chicken, egg yolks, yeast, and
oilseeds.
CHEMISTRYOF VITAMINE
STRUCTURE
STRUCTURE
Sources of vitamin
SunflowerSeeds
 One ounce of dry-
roasted sunflower
seeds delivers 7.4 mg
of vitamin E.
 ALMONDS (7.3 mg of
vitamin E per ounce)
 HAZELNUTS (4.3 mg of
vitamin E per ounce)
 PEANUTS (2.2 mg of
vitamin E per ounce)
 PINENUTS(One ounce of
pine nuts contains 2.6
mg of vitamin E)
Turnip Greens
 A half cup has 2.9 mg
of vitamin E
TOMATOES
 A quarter cup of
tomato paste has
2.8 mg of
vitamin E.
AVOCADO
 Half an avocado
has 2.1 mg of
vitamin E and
161 calories.
Pharmacological properties
1. Prevention of oxidative stress
2. Supporting healthy skin
3. Vitamin E inhibits platelet aggregation
4. Vitamin E may be involved in signal transduction in
neuronal cells
Therapeutic indications
 Angina
pectoris
 Acne
 Alzheimers
disease
 Cancer
 Cataracts
 Diabetes
 Psoriasis
 Parkinsons disease
 Respiratory infection
etc.
CATARACTS
Cataract is caused by metabolic by-products
called free radical
vitamin E supplements can reduce the risk of
cataracts.
It is powerful antioxidant helps to prevent
cataract
Diabetes
1:High does vitamin E appeared to temporarily
improve insulin resistance
2:Vitamin E has also been shown to help some
diabetics gain better control over their blood sugar
Parkinsons disease
High dose vitamin E dietary supplementation or
parenteral vitamin E administration (e.g. vitamin E
succinate) may serve as a successful therapeutic strategy
for the prevention or treatment of PD (by enriching
substantia nigra mito with protective levels of T).
Respiratory Infections
 Vitamin E supplementation has been shown to improve
immune response in the elderly.
 Supplementation with 200 IU per day E significantly
reduced the incidence of common colds in elderly nursing
home residents by 20%
It decrease the risk of acquiring a cold by 21%
deficiency
 In humans, deficiency of vitamin E is seen in
Premature infants
 Transfer of vitamin E from maternal blood occur
during last few weeks of pregnancy
 Premature infants will have vitamin E deficiency
 Impaired absorption: seen in conditions such as
 Abetalipoproteinemia (fat malabsorption)
 Obstructive jaundice
 Intestinal diseases such as celiac sprue
 Genetic vitamin E deficiency:
it is caused by lack of protein that normally
transports 留tocopherol from hepatocytes to
VLDL
 Clinical features:
Hemolytic anemia or macrocytic anemia seen in
premature infants
In adults, increased susceptibility of erythrocytes
for hemolysis under oxidative stress
Muscles weakness and proteinuria is seen.
SIDE EFFECTS/ADVERSE EFFECT
 Taking vitamin E supplements for up to 4 months at doses of 530mg or
800 IU (35 times that current RDA) had no negative side-effect on general
health,
 Body weight
 Level of body proteins lipids level
 liver or kidney function
 Thyroid hormones
 Amount or kinds of blood cells
 And bleeding time over doses may cause nausea, vomiting, diarrheoa
 Vitamin E products in excess of 1200 IU daily may interfere with
absorption and metabolism of vitamins A and k but one can get benefits
with much lower levels of vitamin.
 Individuals who are vitamin K (people who are on blood thinners) deficient
should not take alpha-tocopherol supplements without close medical
supervision because of the increased risk of hemorrhage
Contraindications
 Contraindications have not yet been
identified.
Interactions
1. Vitamin E may increase the anticoagulant
effect of warfarin.
2. may decrease the benefits of atorvastatin
therapy.
3. Plasma levels of vitamin E may be lowered by
anticonvulsants.
PRODUCTS
VITAMINE-GEL:
 An oxidant that repairs and rebuild tissues
 Help to reduce inflammation and damage to
hair follicle.
 Encourages hair growth
BRANDS:
 Vitamin e-gel of desnert brand
 Vitamin E-gel of wallgreens
VITAMINE-OIL:
 It acts as a moisture to your skin.
 It is used as an antiaging products.
 Any kind of scar mainly surgery scars can be
healed
 It hydrates the dehydrated skin.
BRAND NAMES:
 Bella-Terra vitamin E-oil
 Sun-Down vitamin E-oil
NATUREMADE E SUPPLIMENT
 Helps to maintain a healthy heart
 Made up of d-alpha tocopherol the most
active in terms of antioxidant activity.
 A product by USP (united states
pharmacopeia)
Nutrient Interactions
1. Vitamin C
2. Glutathione
3. Selenium
4. Vitamin B3
Deficiency syndrome
1.digestive system problems
2.peripheral neuropathy
Hypervitaminosis
1. Intestinal cramps
2. Diarrhea
3. Fatigue
4. Double vision
5. Muscle weakness
Sources
1. http://www.whfoods.com/genpage.php?tname=nutrient&dbid=111
2. http://painandbrainhealingcenter.com/vitaminearticle.html#.UnnXhHCBlfB
3. http://news.vanderbilt.edu/2012/07/high-consumption-of-vitamin-e-may-lower-
liver-cancer-risk/
4. http://www.antioxidantsdetective.com/vitamin-e-facts.html
5. http://www.webmd.com/vitamins-supplements/ingredientmono-954-
VITAMIN%20E.aspx?activeIngredientId=954&activeIngredientName=VITA
MIN%20E
Thank you.

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Vitamin e by javeria

  • 1. What is Vitamin ?
  • 2. INTRODUCTION Vitamins (English: vital amine, vitamins) are a group of small-molecular-weight organic compound which has a vital function in the metabolism of every organism, which can not be produced by the body. The name is derived from the combination of the Latin word vita which means "life" and amine(amine) that refers to an organic group that has a nitrogen atom (N)
  • 3. Vitamins have a specific role in the body and can also provide health benefits. If levels of these compounds is insufficient, the body can suffer a disease. There are 13 types of vitamins needed by the body to be able to grow and develop properly.
  • 4. VITAMIN E Scientific name of vitamin E is Tocopherol. Vitamin E plays a role in maintaining the health of various tissues in the body, ranging from skin tissue, eyes, red blood cells to the liver. In addition, this vitamin can also protect human lungs from air pollution. Vitamin E is found in fish, chicken, egg yolks, yeast, and oilseeds.
  • 9. SunflowerSeeds One ounce of dry- roasted sunflower seeds delivers 7.4 mg of vitamin E.
  • 10. ALMONDS (7.3 mg of vitamin E per ounce) HAZELNUTS (4.3 mg of vitamin E per ounce) PEANUTS (2.2 mg of vitamin E per ounce) PINENUTS(One ounce of pine nuts contains 2.6 mg of vitamin E)
  • 11. Turnip Greens A half cup has 2.9 mg of vitamin E
  • 12. TOMATOES A quarter cup of tomato paste has 2.8 mg of vitamin E.
  • 13. AVOCADO Half an avocado has 2.1 mg of vitamin E and 161 calories.
  • 14. Pharmacological properties 1. Prevention of oxidative stress 2. Supporting healthy skin 3. Vitamin E inhibits platelet aggregation 4. Vitamin E may be involved in signal transduction in neuronal cells
  • 15. Therapeutic indications Angina pectoris Acne Alzheimers disease Cancer Cataracts Diabetes Psoriasis Parkinsons disease Respiratory infection etc.
  • 16. CATARACTS Cataract is caused by metabolic by-products called free radical vitamin E supplements can reduce the risk of cataracts. It is powerful antioxidant helps to prevent cataract
  • 17. Diabetes 1:High does vitamin E appeared to temporarily improve insulin resistance 2:Vitamin E has also been shown to help some diabetics gain better control over their blood sugar
  • 18. Parkinsons disease High dose vitamin E dietary supplementation or parenteral vitamin E administration (e.g. vitamin E succinate) may serve as a successful therapeutic strategy for the prevention or treatment of PD (by enriching substantia nigra mito with protective levels of T).
  • 19. Respiratory Infections Vitamin E supplementation has been shown to improve immune response in the elderly. Supplementation with 200 IU per day E significantly reduced the incidence of common colds in elderly nursing home residents by 20% It decrease the risk of acquiring a cold by 21%
  • 20. deficiency In humans, deficiency of vitamin E is seen in Premature infants Transfer of vitamin E from maternal blood occur during last few weeks of pregnancy Premature infants will have vitamin E deficiency Impaired absorption: seen in conditions such as Abetalipoproteinemia (fat malabsorption) Obstructive jaundice Intestinal diseases such as celiac sprue
  • 21. Genetic vitamin E deficiency: it is caused by lack of protein that normally transports 留tocopherol from hepatocytes to VLDL Clinical features: Hemolytic anemia or macrocytic anemia seen in premature infants In adults, increased susceptibility of erythrocytes for hemolysis under oxidative stress Muscles weakness and proteinuria is seen.
  • 22. SIDE EFFECTS/ADVERSE EFFECT Taking vitamin E supplements for up to 4 months at doses of 530mg or 800 IU (35 times that current RDA) had no negative side-effect on general health, Body weight Level of body proteins lipids level liver or kidney function Thyroid hormones Amount or kinds of blood cells And bleeding time over doses may cause nausea, vomiting, diarrheoa Vitamin E products in excess of 1200 IU daily may interfere with absorption and metabolism of vitamins A and k but one can get benefits with much lower levels of vitamin. Individuals who are vitamin K (people who are on blood thinners) deficient should not take alpha-tocopherol supplements without close medical supervision because of the increased risk of hemorrhage
  • 23. Contraindications Contraindications have not yet been identified.
  • 24. Interactions 1. Vitamin E may increase the anticoagulant effect of warfarin. 2. may decrease the benefits of atorvastatin therapy. 3. Plasma levels of vitamin E may be lowered by anticonvulsants.
  • 25. PRODUCTS VITAMINE-GEL: An oxidant that repairs and rebuild tissues Help to reduce inflammation and damage to hair follicle. Encourages hair growth BRANDS: Vitamin e-gel of desnert brand Vitamin E-gel of wallgreens
  • 26. VITAMINE-OIL: It acts as a moisture to your skin. It is used as an antiaging products. Any kind of scar mainly surgery scars can be healed It hydrates the dehydrated skin. BRAND NAMES: Bella-Terra vitamin E-oil Sun-Down vitamin E-oil
  • 27. NATUREMADE E SUPPLIMENT Helps to maintain a healthy heart Made up of d-alpha tocopherol the most active in terms of antioxidant activity. A product by USP (united states pharmacopeia)
  • 28. Nutrient Interactions 1. Vitamin C 2. Glutathione 3. Selenium 4. Vitamin B3
  • 29. Deficiency syndrome 1.digestive system problems 2.peripheral neuropathy
  • 30. Hypervitaminosis 1. Intestinal cramps 2. Diarrhea 3. Fatigue 4. Double vision 5. Muscle weakness
  • 31. Sources 1. http://www.whfoods.com/genpage.php?tname=nutrient&dbid=111 2. http://painandbrainhealingcenter.com/vitaminearticle.html#.UnnXhHCBlfB 3. http://news.vanderbilt.edu/2012/07/high-consumption-of-vitamin-e-may-lower- liver-cancer-risk/ 4. http://www.antioxidantsdetective.com/vitamin-e-facts.html 5. http://www.webmd.com/vitamins-supplements/ingredientmono-954- VITAMIN%20E.aspx?activeIngredientId=954&activeIngredientName=VITA MIN%20E