* Over 18 years of research experiences in pharmaceutical company and academic institutions with focus on ophthalmic drug discovery and vascular physiology.
* One patent on novel gene discovery, awarded 4-year research grant from American heart association, two book chapters, several national awards, and over 30 papers in peer-reviewed journals including Nature, PNAS, Circulation.
* Expertise in small interference RNA (siRNA)-based drug target validation and RNA therapeutics. including 1) selection of siRNAs lacking immunostimulatory properties; 2) in vivo siRNA-mediated cleavage assay development; 3) in vivo siRNA efficacy evaluation and 4) in vivo siRNA pharmacokinetics (PK) assay d...