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aortic regurgitation valvular heart disease rhumatic valvular disease cardiology bls acls antiplatelet anticoagulant atrial fibrillation tte asd mitral stenosis rheumatic heart disease rhc cath lab ppm tpm aortic stenosis stent thrombosis timi grade heart failure stemi myocardial infarction unstable angina ventricular arrhythmia atrial arrhythmia hypertension definitions in hypertension mechanical ventilator positive pressure ventilation