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unani medicine unani lateef siddiqui myocardial infarction management of heart failure healthy heart hypertension unani therapy regimenal therapy amal e taleeq leech therapy istefragh irsal e alaq leech hirudo therapy failure cardiac failure cardiac lateef heart failure immunology b cells t cells auto immune diseases cell mediated humoral antibody antigen immune system immunity benefits of leech therapy history of leech therapy hyaluronidase leech saliva composition asbab e sitta zarooriya gntc moalejat govt. nizamia tibbi college regimental therapy risk factors for heart heart