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nephrology mndu dm ckd hd pregnancy kideny mndu8 ln hemodialysis esrd mansoura transplantation women health ckd-mbd challenges in hemodialysis adequacy of hemodialysis renal aki kidney potassium hypomagnesemia hyperkalema hypokalemia vitamin d heart htn therapy volume status colloids plr test crystalloids fluid starch medicine rate ecg axis basics thrombotic microangiopathy tma arrythemia cardiac samir sally uremia vaccination anemia vascular complication hf power gpower pass p value beta alpha error medical statistics size sample hd membrane gn 2018 calcium hypocalcemia hypercalcemia phosphate hyperphosphatemia cvd dynamic static ringer saline rrt plasma lyte