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orthopaedic surgery orthopaedic trauma orthopaedics orthopaedic implants shoulder surgery shoulder trauma ankle joint anatomy biomechanics locking plate philos proximal humerus fractures osteoporosis treatment osteoporotic bone osteoporosis varus deformity knee osteoarthritis dr rohil singh kakkar total knee replacement osteoarthritis surgery shoulder biomechanics clavicle upper limb trauma precontoured plate locking compression plate lcp elbow joint surgery olecranon elbow joint ankle joint biomechanics ankle joint surgery malleolar fractures ankle joint tka tkr oa