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statistics primary care meta-analysis qof ipd heterogeneity general practice databases clinical system emis vision power satisfaction nihr school for primary care cprd ipdforest incentives tci team climate inventory questionnaire quality and outcomes framework cochrane library quality of care royal statistical society systmone diabetes statisti sapc simulation sem gprd structural equation modelling incentivisation hsrn uk primary care databases big data data health and social care information centre hscic mortality international society for clinical biostatistics iscb meta secondary care cochrane library data clinical performance metaeasy one stage exception reporting exceptions stata forest plot metaeasy. royal statistical society rss health services research network