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pcr dna libraray biosafety biopatent agrobacterium tumefaceins bacillus thurengiensis recombinant dna biopiracy restriction fragments bacteriophage ren plasmids gene amplification vector restriction endonuclese transposon polymerase chain reaction cosmids recombinat dna technology biotechnology production of scp from algae scp uses biomass utilization scp protein production in yeast heterologus protein gene expression steroid receptor steroid hormone gene regulation std 12th biology