Assistant Professor at University of Nebraska Medical Center
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My research is focused on the molecular basis of B-cell lymphoma; a disease characterized by the arrested differentiation of B-cells that interact on multiple levels with the immune microenvironment. Specifically, I am interested in the intersection of genetics and immunology, and defining how the mutations in B-cell lymphoma perturb normal B-cell biology and alter interactions with non-malignant immune cells. My approach employs genomic screens and bioinformatics for the discovery of disease-specific or subtype-specific alterations that alter B-cell differentiation or immune interactions and have potential for therapeutic correction. I define the biological consequences of these alterati...
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