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Why Artemisinin Based Combination effectively cure malaria?

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Min Zaw
Min Zaw

ACT is one of the effective treatment of Malaria especially in the areas where multi-drug resistant issues raise.

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What is malaria?
What causes malaria? X X
How many types of Malaria parasites in Myanmar? 4Uncomplicated Severe & lethal Caused by all Caused by f malaria
Why is f malaria dangerous? 1 30,000 0.25-1million 7days 2days = X8-30 every 2 days
How do we recognize severe malaria caused by f malaria? Can we guess what is she suffering? Can we recognize f malaria from other malaria?
What will happen if not treat? Especially f malaria Loss of consciousness fits Jaundice due to Liver damage Severe anemia
How can we immediately know malaria infection?
Malaria treatment drugs in the market and their efficacy: Chloroquin Quinine Mefloquin Artesunate Artemether Tx days Side effects resistance 3 5 1 3 moderate moderate moderate rare High High High minimal Which drug will you choose?
If use Artemisinin drug alone? Parasite burden; 100 millions to 1000 billions Parasite burden reduces to 80% Artemether or Artesunate Artemisinin resistant parasite Artemisinin sensitive parasite
If Artemisinin and other effective drug are given together: Parasite burden; 100 millions to 1000 billions Parasite burden reduces to 80% Gradual clearance of parasite Artemether or Artesunate Lumefantrine or Mefloquin +
Is it curable?
Can we prevent it? Sleeping under insecticide treated bednet Taking ACT as early as possible

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Why Artemisinin Based Combination effectively cure malaria?

  • 3. How many types of Malaria parasites in Myanmar? 4Uncomplicated Severe & lethal Caused by all Caused by f malaria
  • 4. Why is f malaria dangerous? 1 30,000 0.25-1million 7days 2days = X8-30 every 2 days
  • 5. How do we recognize severe malaria caused by f malaria? Can we guess what is she suffering? Can we recognize f malaria from other malaria?
  • 6. What will happen if not treat? Especially f malaria Loss of consciousness fits Jaundice due to Liver damage Severe anemia
  • 7. How can we immediately know malaria infection?
  • 8. Malaria treatment drugs in the market and their efficacy: Chloroquin Quinine Mefloquin Artesunate Artemether Tx days Side effects resistance 3 5 1 3 moderate moderate moderate rare High High High minimal Which drug will you choose?
  • 9. If use Artemisinin drug alone? Parasite burden; 100 millions to 1000 billions Parasite burden reduces to 80% Artemether or Artesunate Artemisinin resistant parasite Artemisinin sensitive parasite
  • 10. If Artemisinin and other effective drug are given together: Parasite burden; 100 millions to 1000 billions Parasite burden reduces to 80% Gradual clearance of parasite Artemether or Artesunate Lumefantrine or Mefloquin +
  • 12. Can we prevent it? Sleeping under insecticide treated bednet Taking ACT as early as possible