This document summarizes the clinical features, treatment options, and pharmacotherapy for alcohol use disorder. The clinical features include drinking large amounts and being unable to cut down, craving alcohol, drinking in hazardous situations, and continued drinking despite health or relationship problems. Treatment involves motivational interviewing, cognitive-behavioral therapy, residential programs, and mutual help groups. Pharmacotherapy includes naltrexone, acamprosate which is preferred for liver disease or opioid use, and disulfiram as second-line therapy for highly motivated patients.
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Alcohol use disorder HY
1. Alcohol use disorder
Clinical features
• Drinking in larger amounts, inability to cut down,
cravings
• Drinking in hazardous situations, failure to fulfill role
obligations, continued drinking despite health/
psychological/ interpersonal problems
• Evidence of tolerance & withdrawal
Psychosocial
treatment
• Motivational interviewing
• Cognitive-behavioral therapy
• Residential treatment/rehabilitation
• Mutual help groups (eg, Alcoholics Anonymous)
Pharmacotherapy
• Naltrexone
• Acamprosate (preferred in patients with liver disease or
opioid use)
• Disulfiram is second-line therapy in highly motivated
patients