This document discusses the four main types of lung cancer: adenocarcinoma, squamous cell carcinoma, small cell carcinoma, and large cell carcinoma. It provides information on the incidence, typical location in the lungs, and common clinical associations for each type of lung cancer. Adenocarcinoma makes up 40-50% of lung cancers and is usually located in the periphery of the lungs. Squamous cell carcinoma accounts for 20-25% of cases and is typically central. Small cell carcinoma comprises 10-15% of lung cancers and is also usually central. Large cell carcinoma represents 5-10% of lung cancers and tends to be peripheral.
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Lung cancer HY
1. Lung cancer
Tumor type Incidence Location Clinical associations
Adenocarcinoma 40%-50% Peripheral
? Clubbing
? Hypertrophic
osteoarthropathy
Squamous cell
carcinoma
20%-25% Central
? Hypercalcemia
? Necrosis & cavitation
Small cell
carcinoma
10%-15% Central
? Cushing syndrome
? SIADH
? Lambert-Eaton syndrome
Large cell
carcinoma
5%-10% Peripheral
? Gynecomastia
? Galactorrhea
SIADH = syndrome of inappropriate antidiuretic hormone.