I'm working and also playing with the most beautiful creature in nature, namely fruit fly Drosophila melanogaster. I trained as a molecular virologist at POSTECH in Korea working on the relationship between inflammatory response and eukartyotic translational initiation mechanism. During that period, I firstly identified TRAF2 which is very important adapter protein for TNF-alpha signaling interacts with eIF4GI which is key scaffold protein bridging the most of translational initiation factors. Important aspect of this interaction is their context-dependecy. By this interaction, cells can be prepared to be healed from the heat shock stress. I also identified 15d-PGJ2 which had been known t...
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