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Cost Benefit study of vaccination
A cost benefit study applied to
vaccination compares
the costs of vaccination vs the
costs if no-vaccination
Cost savings
= (indirect + direct costs if no
vaccination) - (indirect + direct
costs of vaccination)

 Direct costs are the
costs of disease
(outpatient visits,
hospitalization days)
 Indirect costs are the
costs of absenteeism
Economic benefit of Flu vaccination in company
during winter
(Poland)

No of Absenteeism days

Vaccinated

Unvaccinated

350

Cost for prevention Cost due to Flu
Direct cost

300

Vaccine cost=$4364

250

Direct Costs

Administration cost=$154

200

Indirect costs

150

Cost of side
effects=$290

100
50
0

Total cost=$4808
D辿c

Janv

Feb

Mar

Reduction of
absenteeism
by 50 %

Medical costs=0

Indirect costs
Absenteeism
costs=$5985

Total cost=$5985

Apr

Direct savings : $1177 per year
Radiziszewski N, British Camber of commerce in
Poland, No 4/97
Economic benefit of flu vaccination in Healthy
Working Population (United States)
Saved lost workdays
%
Unvaccinated Vaccinated
70
60
50
40
30
20
10
0

Saved lost workdays
%
Unvaccinated Vaccinated
35
30
25
20
15
10
5
0

Reduction of
Reduction of missed
Influenza Like Illness
work
by 60 %
Direct savings : $22,36 per saved work days by 50 %
$2.58 per dollars invested in the vaccination
Campbell et al, JOEM vol 39, Number 5 May
1997
Sickness absence following a campaign of
vaccination against influenza in the workplace



Retrospective cohort study (UK);
Outcome: self reported I.L.I., reduction in sickness
absence;
 Sample: 601 vaccinated w/ flu vaccine,
1956 unvaccinated;
 Results:
 46 % reduction in influenza sickness.

Leighton et al., Occup Med (1995) 46(2):146-50
The effectiveness of vaccination
agains influenza in healthy working adults
Health-related benefits associated with vaccination in 1994-95 season
in 849 subjects from 18 to 64 years of age (USA)
No vaccinated
Vaccinated
125
100

Absenteeism:
Reduced 43%

75
50
25
0

Total sick day
NICHOL KL, Lind A, Margolis KL and al. The effectiveness of vaccination against influenza in
healthy
working adults NEJM 1995;333:889-893
Conclusion:

Vaccination is the best tools against
communicable diseases
 Preventive is better than curative







Reduce the probability of being sick,
Reduce absenteeism
Reduce hospitalization cost
Reduce Medical cost
Prevent other costs
No guilty feeling (spreading infectious
diseases to friends and family)

In Short: Cost effective !
Conclusion:

Vaccination is the best tools against
communicable diseases
 Preventive is better than curative







Reduce the probability of being sick,
Reduce absenteeism
Reduce hospitalization cost
Reduce Medical cost
Prevent other costs
No guilty feeling (spreading infectious
diseases to friends and family)

In Short: Cost effective !

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Cost benefit ratio

  • 1. Cost Benefit study of vaccination A cost benefit study applied to vaccination compares the costs of vaccination vs the costs if no-vaccination Cost savings = (indirect + direct costs if no vaccination) - (indirect + direct costs of vaccination) Direct costs are the costs of disease (outpatient visits, hospitalization days) Indirect costs are the costs of absenteeism
  • 2. Economic benefit of Flu vaccination in company during winter (Poland) No of Absenteeism days Vaccinated Unvaccinated 350 Cost for prevention Cost due to Flu Direct cost 300 Vaccine cost=$4364 250 Direct Costs Administration cost=$154 200 Indirect costs 150 Cost of side effects=$290 100 50 0 Total cost=$4808 D辿c Janv Feb Mar Reduction of absenteeism by 50 % Medical costs=0 Indirect costs Absenteeism costs=$5985 Total cost=$5985 Apr Direct savings : $1177 per year Radiziszewski N, British Camber of commerce in Poland, No 4/97
  • 3. Economic benefit of flu vaccination in Healthy Working Population (United States) Saved lost workdays % Unvaccinated Vaccinated 70 60 50 40 30 20 10 0 Saved lost workdays % Unvaccinated Vaccinated 35 30 25 20 15 10 5 0 Reduction of Reduction of missed Influenza Like Illness work by 60 % Direct savings : $22,36 per saved work days by 50 % $2.58 per dollars invested in the vaccination Campbell et al, JOEM vol 39, Number 5 May 1997
  • 4. Sickness absence following a campaign of vaccination against influenza in the workplace Retrospective cohort study (UK); Outcome: self reported I.L.I., reduction in sickness absence; Sample: 601 vaccinated w/ flu vaccine, 1956 unvaccinated; Results: 46 % reduction in influenza sickness. Leighton et al., Occup Med (1995) 46(2):146-50
  • 5. The effectiveness of vaccination agains influenza in healthy working adults Health-related benefits associated with vaccination in 1994-95 season in 849 subjects from 18 to 64 years of age (USA) No vaccinated Vaccinated 125 100 Absenteeism: Reduced 43% 75 50 25 0 Total sick day NICHOL KL, Lind A, Margolis KL and al. The effectiveness of vaccination against influenza in healthy working adults NEJM 1995;333:889-893
  • 6. Conclusion: Vaccination is the best tools against communicable diseases Preventive is better than curative Reduce the probability of being sick, Reduce absenteeism Reduce hospitalization cost Reduce Medical cost Prevent other costs No guilty feeling (spreading infectious diseases to friends and family) In Short: Cost effective !
  • 7. Conclusion: Vaccination is the best tools against communicable diseases Preventive is better than curative Reduce the probability of being sick, Reduce absenteeism Reduce hospitalization cost Reduce Medical cost Prevent other costs No guilty feeling (spreading infectious diseases to friends and family) In Short: Cost effective !