The document discusses organ preservation techniques for cancer patients at Mahatma Gandhi Cancer Hospital & Research Institute in Visakhapatnam, India. It provides examples of patients who underwent organ preservation procedures for cancers of the lip, tongue, soft palate and other sites. Intracavitary radiation therapy and brachytherapy are used to deliver high radiation doses directly to tumors while sparing surrounding healthy tissues and organs. This allows for organ preservation and improved quality of life outcomes for patients.
Dr. Zhen Yang - Understanding frequency of PCV3 Infection and PCV3-Associated...John Blue
油
This document discusses the frequency of PCV3 infection and associated disease. Some key points:
- PCV3 was first identified in the US in 2016 and has since been found in many countries worldwide.
- Historical sampling found evidence of PCV3 circulation globally for years prior to 2016 identification.
- PCV3 is genetically distinct from PCV1 and PCV2, sharing less than 50% genetic identity.
- The document analyzes PCV3 prevalence in US samples and its association with clinical signs and lesions. PCV3 was found in 27% of US samples and was associated with abortion, myocarditis, and vasculitis.
This research article investigated associations between polymorphisms in the NRAMP1 and VDR genes and susceptibility to tuberculosis infection and disease progression in a Venezuelan population. The results showed that variants in the NRAMP1 3'UTR region were associated with susceptibility to M. tuberculosis infection, as seen in comparisons between tuberculosis-infected and uninfected controls, and with progression to active tuberculosis disease, as shown in comparisons between tuberculosis patients and infected controls. In contrast, no associations were found between variants in the VDR gene and tuberculosis susceptibility. This study confirms that NRAMP1 3'UTR polymorphisms are associated with M. tuberculosis infection and disease progression in this Venezuelan population.
Los d鱈as 7 y 8 de mayo organizamos en la Fundaci坦n Ram坦n Areces con la Fundaci坦n General CSIC el Simposio Internacional 'Microbiolog鱈a: transmisi坦n'. La "transmisi坦n" en microbiolog鱈a hace referencia al proceso por el que material gen辿tico es transferido de una c辿lula a otra, de una poblaci坦n a otra. Es un proceso clave para entender el origen y la evoluci坦n de los seres vivos. El objetivo de esta reuni坦n era conocer mejor la log鱈stica de la transmisi坦n para ser capaces de modular o suprimir algunos procesos de transmisi坦n da単inos.
Japanese encephalitis is a mosquito-borne viral disease transmitted between pigs and birds, with Culex mosquitoes as vectors. It was first reported in Japan in 1871 and India in 1952. It is a leading cause of viral neurological disease in Asia, with up to 50,000 reported cases and 10,000-15,000 deaths annually. The virus causes fever, headache, abnormal behavior and potentially seizures, paralysis or death. A vaccine was developed in 1983 and is now used in vaccination programs in affected areas, though efficacy must be monitored. Analysis of samples from northeast India found a 36.88% positivity rate, with most cases in children living near pigs without mosquito nets or in water-logged areas near
Tetanus is caused by Clostridium tetani which produces a neurotoxin called tetanospasmin. This neurotoxin binds to motor neurons and prevents the release of inhibitory neurotransmitters, leading to uncontrolled muscle contractions characteristic of tetanus. Treatment involves wound cleaning, tetanus immunoglobulin, antibiotics such as metronidazole, and muscle relaxants like diazepam to control spasms. Prognosis depends on the severity and location of symptoms, with generalized tetanus carrying the highest risk.
The document discusses depression and psychosis, including their diagnosis, treatment, and management. It covers pharmacological interventions like antidepressants and antipsychotics, as well as psychosocial interventions. Key points include:
- Amitriptyline can be used for depression but avoided in cardiovascular disease. Fluoxetine is preferred for adolescents, pregnant/breastfeeding women, and those with suicidal ideation.
- Diagnosis of depression includes markedly diminished interest or pleasure in activities.
- Psychosis treatment requires starting antipsychotics immediately. Injection is not always preferred due to adherence issues.
- Psychosocial interventions for both include psychoeducation, encouraging activities, and clarifying misconceptions to avoid criticism and long
The document discusses various concepts in epidemiology including:
1) The epidemiologic triangle which includes the agent, host, and environment as factors that influence disease.
2) Observational study designs like cross-sectional studies which assess disease prevalence at a point in time, and cohort studies which follow groups over time to compare disease rates between exposed and unexposed individuals.
3) Key figures in the history of epidemiology like John Snow who conducted seminal investigations tracing cholera outbreaks to contaminated water sources in London in the 1850s.
4) The overall goal of epidemiology is to identify and quantify relationships between exposures and health outcomes in populations in order to control disease. Descriptive and analytical approaches are used.
1. The document discusses how genetic information is carried from generation to generation through inheritance.
2. It provides information on chromosomes, DNA, genes, and how genetic traits are passed down based on whether they are dominant or recessive.
3. Specifically, it examines the inheritance patterns of thalassemia, an autosomal recessive blood disorder common in the region, and how carriers of the genes can be found in up to 40% of the local population.
At Macafem, we provide 100% natural support for women navigating menopause. For over 20 years, we've helped women manage symptoms, and in 2024, we're proud to share their heartfelt experiences.
Flag Screening in Physiotherapy Examination.pptxBALAJI SOMA
油
Flag screening is a crucial part of physiotherapy assessment that helps in identifying medical, psychological, occupational, and social barriers to recovery. Recognizing these flags ensures that physiotherapists make informed decisions, provide holistic care, and refer patients appropriately when necessary. By integrating flag screening into practice, physiotherapists can optimize patient outcomes and prevent chronicity of conditions.
Presentaci坦 que va acompanyar la demostraci坦 prctica de metge d'Innovaci坦 Jos辿 Ferrer sobre el projecte Benestar de BSA, nom d'IDIAP Pere Gol, el 5 de mar巽 de 2025 a l'estand de XarSMART al Mobible Word Congress.
Acute & Chronic Inflammation, Chemical mediators in Inflammation and Wound he...Ganapathi Vankudoth
油
A complete information of Inflammation, it includes types of Inflammation, purpose of Inflammation, pathogenesis of acute inflammation, chemical mediators in inflammation, types of chronic inflammation, wound healing and Inflammation in skin repair, phases of wound healing, factors influencing wound healing and types of wound healing.
The course covers the steps undertaken from tissue collection, reception, fixation,
sectioning, tissue processing and staining. It covers all the general and special
techniques in histo/cytology laboratory. This course will provide the student with the
basic knowledge of the theory and practical aspect in the diagnosis of tumour cells
and non-malignant conditions in body tissues and for cytology focusing on
gynaecological and non-gynaecological samples.
Stability of Dosage Forms as per ICH GuidelinesKHUSHAL CHAVAN
油
This presentation covers the stability testing of pharmaceutical dosage forms according to ICH guidelines (Q1A-Q1F). It explains the definition of stability, various testing protocols, storage conditions, and evaluation criteria required for regulatory submissions. Key topics include stress testing, container closure systems, stability commitment, and photostability testing. The guidelines ensure that pharmaceutical products maintain their identity, purity, strength, and efficacy throughout their shelf life. This resource is valuable for pharmaceutical professionals, researchers, and regulatory experts.
Rabies Bali 2008-2020_WRD Webinar_WSAVA 2020_Final.pptxWahid Husein
油
A decade of rabies control programmes in Bali with support from FAO ECTAD Indonesia with Mass Dog Vaccination, Integrated Bite Case Management, Dog Population Management, and Risk Communication as the backbone of the programmes
1. Explain the physiological control of glomerular filtration and renal blood flow
2. Describe the humoral and autoregulatory feedback mechanisms that mediate the autoregulation of renal plasma flow and glomerular filtration rate
Tetanus is caused by Clostridium tetani which produces a neurotoxin called tetanospasmin. This neurotoxin binds to motor neurons and prevents the release of inhibitory neurotransmitters, leading to uncontrolled muscle contractions characteristic of tetanus. Treatment involves wound cleaning, tetanus immunoglobulin, antibiotics such as metronidazole, and muscle relaxants like diazepam to control spasms. Prognosis depends on the severity and location of symptoms, with generalized tetanus carrying the highest risk.
The document discusses depression and psychosis, including their diagnosis, treatment, and management. It covers pharmacological interventions like antidepressants and antipsychotics, as well as psychosocial interventions. Key points include:
- Amitriptyline can be used for depression but avoided in cardiovascular disease. Fluoxetine is preferred for adolescents, pregnant/breastfeeding women, and those with suicidal ideation.
- Diagnosis of depression includes markedly diminished interest or pleasure in activities.
- Psychosis treatment requires starting antipsychotics immediately. Injection is not always preferred due to adherence issues.
- Psychosocial interventions for both include psychoeducation, encouraging activities, and clarifying misconceptions to avoid criticism and long
The document discusses various concepts in epidemiology including:
1) The epidemiologic triangle which includes the agent, host, and environment as factors that influence disease.
2) Observational study designs like cross-sectional studies which assess disease prevalence at a point in time, and cohort studies which follow groups over time to compare disease rates between exposed and unexposed individuals.
3) Key figures in the history of epidemiology like John Snow who conducted seminal investigations tracing cholera outbreaks to contaminated water sources in London in the 1850s.
4) The overall goal of epidemiology is to identify and quantify relationships between exposures and health outcomes in populations in order to control disease. Descriptive and analytical approaches are used.
1. The document discusses how genetic information is carried from generation to generation through inheritance.
2. It provides information on chromosomes, DNA, genes, and how genetic traits are passed down based on whether they are dominant or recessive.
3. Specifically, it examines the inheritance patterns of thalassemia, an autosomal recessive blood disorder common in the region, and how carriers of the genes can be found in up to 40% of the local population.
At Macafem, we provide 100% natural support for women navigating menopause. For over 20 years, we've helped women manage symptoms, and in 2024, we're proud to share their heartfelt experiences.
Flag Screening in Physiotherapy Examination.pptxBALAJI SOMA
油
Flag screening is a crucial part of physiotherapy assessment that helps in identifying medical, psychological, occupational, and social barriers to recovery. Recognizing these flags ensures that physiotherapists make informed decisions, provide holistic care, and refer patients appropriately when necessary. By integrating flag screening into practice, physiotherapists can optimize patient outcomes and prevent chronicity of conditions.
Presentaci坦 que va acompanyar la demostraci坦 prctica de metge d'Innovaci坦 Jos辿 Ferrer sobre el projecte Benestar de BSA, nom d'IDIAP Pere Gol, el 5 de mar巽 de 2025 a l'estand de XarSMART al Mobible Word Congress.
Acute & Chronic Inflammation, Chemical mediators in Inflammation and Wound he...Ganapathi Vankudoth
油
A complete information of Inflammation, it includes types of Inflammation, purpose of Inflammation, pathogenesis of acute inflammation, chemical mediators in inflammation, types of chronic inflammation, wound healing and Inflammation in skin repair, phases of wound healing, factors influencing wound healing and types of wound healing.
The course covers the steps undertaken from tissue collection, reception, fixation,
sectioning, tissue processing and staining. It covers all the general and special
techniques in histo/cytology laboratory. This course will provide the student with the
basic knowledge of the theory and practical aspect in the diagnosis of tumour cells
and non-malignant conditions in body tissues and for cytology focusing on
gynaecological and non-gynaecological samples.
Stability of Dosage Forms as per ICH GuidelinesKHUSHAL CHAVAN
油
This presentation covers the stability testing of pharmaceutical dosage forms according to ICH guidelines (Q1A-Q1F). It explains the definition of stability, various testing protocols, storage conditions, and evaluation criteria required for regulatory submissions. Key topics include stress testing, container closure systems, stability commitment, and photostability testing. The guidelines ensure that pharmaceutical products maintain their identity, purity, strength, and efficacy throughout their shelf life. This resource is valuable for pharmaceutical professionals, researchers, and regulatory experts.
Rabies Bali 2008-2020_WRD Webinar_WSAVA 2020_Final.pptxWahid Husein
油
A decade of rabies control programmes in Bali with support from FAO ECTAD Indonesia with Mass Dog Vaccination, Integrated Bite Case Management, Dog Population Management, and Risk Communication as the backbone of the programmes
1. Explain the physiological control of glomerular filtration and renal blood flow
2. Describe the humoral and autoregulatory feedback mechanisms that mediate the autoregulation of renal plasma flow and glomerular filtration rate
Optimization in Pharmaceutical Formulations: Concepts, Methods & ApplicationsKHUSHAL CHAVAN
油
This presentation provides a comprehensive overview of optimization in pharmaceutical formulations. It explains the concept of optimization, different types of optimization problems (constrained and unconstrained), and the mathematical principles behind formulation development. Key topics include:
Methods for optimization (Sequential Simplex Method, Classical Mathematical Methods)
Statistical analysis in optimization (Mean, Standard Deviation, Regression, Hypothesis Testing)
Factorial Design & Quality by Design (QbD) for process improvement
Applications of optimization in drug formulation
This resource is beneficial for pharmaceutical scientists, R&D professionals, regulatory experts, and students looking to understand pharmaceutical process optimization and quality by design approaches.
1. WHO HIV STAGING IN
ADULT
DR. ARKAR LINN NAING
CLINICAL CONSULTANT
MAE TAO CLINIC
22ND AUGUST 2017
Dr. Rebecca
Volunteer Doctor
Mae Tao Clinic
May to July 2017
Reference: WHO case definition for HIV staging, 2007