This document provides an overview of Good Manufacturing Practices (GMP) guidelines from various regulatory authorities like WHO, US FDA, ICH, and MHRA. It discusses the objectives of GMPs, including ensuring product quality and compliance. The key GMP guidelines from WHO, US FDA, and ICH are summarized, covering topics like pharmaceutical quality systems, sanitation procedures, and guidelines for quality control. Validation is also discussed as important for quality assurance and reducing compliance issues.
Este documento describe los efectos halo y Pigmali坦n. El efecto halo es la tendencia a evaluar a alguien de manera positiva o negativa basado en una caracter鱈stica en particular. El efecto Pigmali坦n ocurre cuando las expectativas que se tienen de alguien afectan su comportamiento de tal forma que se cumple la profec鱈a. Estos efectos pueden ser positivos o negativos y ocurren en 叩mbitos como la educaci坦n, el trabajo y la sociedad.
When a plano-convex lens is placed on a glass plate, an air film of varying thickness is formed between the two surfaces. Light reflected from the two surfaces interferes, producing concentric bright and dark rings called Newton's rings. The document describes the theory of interference in the air film and how it relates to the thickness of the film and the radii of the interference rings observed. It provides procedures for using a traveling microscope to measure the ring radii and calculate the wavelength of monochromatic light from the relationship between ring order number and optical path difference.
Rapid prototyping techniques allow designers to quickly produce physical prototypes directly from 3D CAD models without special tooling. While useful for visualization, RP prototypes often cannot undergo functional testing due to different material properties than production parts. Rapid tooling produces molds or tools using RP to enable functional prototype testing and production of multiple prototype parts. It has advantages over conventional tooling like shorter timelines, lower costs, and longer tool life. Common rapid tooling methods include soft tooling using silicone rubber molds, epoxy or hybrid molds, and direct metal laser sintering or wire arc spray to produce metal tool inserts.
Rapid prototyping techniques allow designers to quickly produce physical prototypes directly from 3D CAD models without special tooling. While useful for visualization, RP prototypes often cannot undergo functional testing due to different material properties than production parts. Rapid tooling produces molds or tools using RP to enable functional prototype testing and production of multiple prototype parts. It has advantages over conventional tooling like shorter timelines, lower costs, and longer tool life. Common rapid tooling methods include soft tooling using silicone rubber molds, epoxy or hybrid molds, and direct metal laser sintering or wire arc spray to produce metal tool inserts.