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brain hypertension pregnancy cerebral cortex sle posterior circulation blood pressure hypothyroidism thyroid hyperthyroidism lupus jnc 7 hypoglycaemia beta blockers hypoglycemia anemia anaemia spinal cord blood supply hyperosmolar coma hhs honc brodmann cerebral aace statins acc ldl esc dyslipidemia pre-ecclampsia ecclampsia nice pih sadiq dash morning surge cardiovascular disease vulvovaginitis watery leak pv pprom ectopic cerazette ramadan diabetes sick euthyroid syndrome subclinical hypothyroidism